new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 348 hits with Last Name = 'denora' and Initial = 'n'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274351
PNG
(2-(6,8-Dichloro-2-(4-nitrophenyl)imidazo[1,2-a]pyr...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C21H22Cl2N4O3/c1-3-9-25(10-4-2)19(28)12-18-20(14-5-7-16(8-6-14)27(29)30)24-21-17(23)11-15(22)13-26(18)21/h5-8,11,13H,3-4,9-10,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.150n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159077
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES CN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H16Cl3N3O/c1-27(17-5-3-2-4-6-17)20(29)12-19-21(14-7-9-15(23)10-8-14)26-22-18(25)11-16(24)13-28(19)22/h2-11,13H,12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.203n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274260
PNG
(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Show SMILES COc1ccc(cc1)-c1nc2c(Cl)cc(Cl)cn2c1CC(=O)N(C)c1ccccc1
Show InChI InChI=1S/C23H19Cl2N3O2/c1-27(17-6-4-3-5-7-17)21(29)13-20-22(15-8-10-18(30-2)11-9-15)26-23-19(25)12-16(24)14-28(20)23/h3-12,14H,13H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.230n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274403
PNG
(2-(6,8-Dichloro-2-(4-chloro-3-nitrophenyl)imidazo[...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C21H21Cl3N4O3/c1-3-7-26(8-4-2)19(29)11-18-20(13-5-6-15(23)17(9-13)28(30)31)25-21-16(24)10-14(22)12-27(18)21/h5-6,9-10,12H,3-4,7-8,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.240n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274404
PNG
(CHEMBL521180 | N-Butyl-2-(6,8-dichloro-2-(4-chloro...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H19Cl3N4O3/c1-3-4-7-25(2)18(28)10-17-19(12-5-6-14(22)16(8-12)27(29)30)24-20-15(23)9-13(21)11-26(17)20/h5-6,8-9,11H,3-4,7,10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.300n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159075
PNG
(CHEMBL180210 | N-Butyl-2-[6,8-dichloro-2-(4-chloro...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H20Cl3N3O/c1-3-4-9-25(2)18(27)11-17-19(13-5-7-14(21)8-6-13)24-20-16(23)10-15(22)12-26(17)20/h5-8,10,12H,3-4,9,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.302n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274258
PNG
(2-(6,8-Dichloro-2-(4-methoxyphenyl)imidazo[1,2-a]p...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C22H25Cl2N3O2/c1-4-10-26(11-5-2)20(28)13-19-21(15-6-8-17(29-3)9-7-15)25-22-18(24)12-16(23)14-27(19)22/h6-9,12,14H,4-5,10-11,13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.310n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274219
PNG
(2-(6,8-Dichloro-2-(4-hydroxyphenyl)imidazo[1,2-a]p...)
Show SMILES CN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(O)cc1)c1ccccc1
Show InChI InChI=1S/C22H17Cl2N3O2/c1-26(16-5-3-2-4-6-16)20(29)12-19-21(14-7-9-17(28)10-8-14)25-22-18(24)11-15(23)13-27(19)22/h2-11,13,28H,12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.320n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274406
PNG
(2-(2-(3-Amino-4-chlorophenyl)-6,8-dichloroimidazo[...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)c(N)c1
Show InChI InChI=1S/C21H23Cl3N4O/c1-3-7-27(8-4-2)19(29)11-18-20(13-5-6-15(23)17(25)9-13)26-21-16(24)10-14(22)12-28(18)21/h5-6,9-10,12H,3-4,7-8,11,25H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.330n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM22032
PNG
(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Show SMILES CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl
Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
0.400n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat C6 cell membrane after 90 mins by radioligand binding assay


ACS Med Chem Lett 5: 685-9 (2014)


Article DOI: 10.1021/ml5000788
BindingDB Entry DOI: 10.7270/Q26D5VKG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274406
PNG
(2-(2-(3-Amino-4-chlorophenyl)-6,8-dichloroimidazo[...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)c(N)c1
Show InChI InChI=1S/C21H23Cl3N4O/c1-3-7-27(8-4-2)19(29)11-18-20(13-5-6-15(23)17(25)9-13)26-21-16(24)10-14(22)12-28(18)21/h5-6,9-10,12H,3-4,7-8,11,25H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.450n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Cholinesterase


(Equus caballus (Horse))
BDBM50210854
PNG
(CHEMBL3960040)
Show SMILES Fc1cccc(CCn2c3CCCNC(=O)c3c3ccccc23)c1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.700n/an/an/an/an/an/an/an/a



University of Bari"A. Moro"

Curated by ChEMBL


Assay Description
Competitive inhibition of horse serum BChE in presence of varying levels of butyrylthiocholine iodide substrate by Lineweaver-burk plot method


Eur J Med Chem 125: 288-298 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.037
BindingDB Entry DOI: 10.7270/Q2G44S9D
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274259
PNG
(CHEMBL521186 | N-Butyl-2-(6,8-dichloro-2-(4-methox...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OC)cc1
Show InChI InChI=1S/C21H23Cl2N3O2/c1-4-5-10-25(2)19(27)12-18-20(14-6-8-16(28-3)9-7-14)24-21-17(23)11-15(22)13-26(18)21/h6-9,11,13H,4-5,10,12H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.730n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274484
PNG
(2-(2-(3-Amino-4-chlorophenyl)-6,8-dichloroimidazo[...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)c(N)c1
Show InChI InChI=1S/C20H21Cl3N4O/c1-3-4-7-26(2)18(28)10-17-19(12-5-6-14(22)16(24)8-12)25-20-15(23)9-13(21)11-27(17)20/h5-6,8-9,11H,3-4,7,10,24H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.780n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50419716
PNG
(CHEMBL1946777)
Show SMILES COc1ccccc1N1CCN(CC2COC(O2)(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C27H30N2O3/c1-30-26-15-9-8-14-25(26)29-18-16-28(17-19-29)20-24-21-31-27(32-24,22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15,24H,16-21H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.813n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274561
PNG
(4-(2-(4-Chlorophenyl)-3-(2-(dipropylamino)-2-oxoet...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(NC(=O)CCC(=O)OCC)cccn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C27H33ClN4O4/c1-4-15-31(16-5-2)24(34)18-22-26(19-9-11-20(28)12-10-19)30-27-21(8-7-17-32(22)27)29-23(33)13-14-25(35)36-6-3/h7-12,17H,4-6,13-16,18H2,1-3H3,(H,29,33)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.860n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274218
PNG
(2-(6,8-Dichloro-2-(4-hydroxyphenyl)imidazo[1,2-a]p...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(O)cc1
Show InChI InChI=1S/C20H21Cl2N3O2/c1-3-4-9-24(2)18(27)11-17-19(13-5-7-15(26)8-6-13)23-20-16(22)10-14(21)12-25(17)20/h5-8,10,12,26H,3-4,9,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.870n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159085
PNG
(CHEMBL359593 | N-Butyl-2-[6-chloro-2-(4-chloro-phe...)
Show SMILES CCCCN(C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H23Cl2N3O/c1-2-3-15-29(21-7-5-4-6-8-21)24(31)16-22-25(18-9-11-19(26)12-10-18)28-23-14-13-20(27)17-30(22)23/h4-14,17H,2-3,15-16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.884n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50210789
PNG
(CHEMBL3938383)
Show SMILES COc1ccccc1OCCNCC1CSC2(CCCCC2)S1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.933n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274485
PNG
(2-(2-(3-Amino-4-chlorophenyl)-8-chloroimidazo[1,2-...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cccn12)-c1ccc(Cl)c(N)c1
Show InChI InChI=1S/C20H22Cl2N4O/c1-3-4-9-25(2)18(27)12-17-19(13-7-8-14(21)16(23)11-13)24-20-15(22)6-5-10-26(17)20/h5-8,10-11H,3-4,9,12,23H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.04n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM22032
PNG
(1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...)
Show SMILES CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl
Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
1.14n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274405
PNG
(CHEMBL485218 | N-Butyl-2-(8-chloro-2-(4-chloro-3-n...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cccn12)-c1ccc(Cl)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C20H20Cl2N4O3/c1-3-4-9-24(2)18(27)12-17-19(23-20-15(22)6-5-10-25(17)20)13-7-8-14(21)16(11-13)26(28)29/h5-8,10-11H,3-4,9,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.16n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159077
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES CN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H16Cl3N3O/c1-27(17-5-3-2-4-6-17)20(29)12-19-21(14-7-9-15(23)10-8-14)26-22-18(25)11-16(24)13-28(19)22/h2-11,13H,12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Alpha-1D adrenergic receptor


(Homo sapiens (Human))
BDBM50026917
PNG
(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50026917
PNG
(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
Show InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274217
PNG
(2-(6,8-Dichloro-2-(4-hydroxyphenyl)imidazo[1,2-a]p...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(O)cc1
Show InChI InChI=1S/C21H23Cl2N3O2/c1-3-9-25(10-4-2)19(28)12-18-20(14-5-7-16(27)8-6-14)24-21-17(23)11-15(22)13-26(18)21/h5-8,11,13,27H,3-4,9-10,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.31n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159102
PNG
(CHEMBL430139 | N-Benzyl-2-[6,8-dichloro-2-(4-chlor...)
Show SMILES CN(Cc1ccccc1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H18Cl3N3O/c1-28(13-15-5-3-2-4-6-15)21(30)12-20-22(16-7-9-17(24)10-8-16)27-23-19(26)11-18(25)14-29(20)23/h2-11,14H,12-13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.40n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274562
PNG
(2-(6,8-dichloro-2-(thiazol-2-yl)H-imidazo[1,2-a]py...)
Show SMILES CN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1nccs1)c1ccccc1
Show InChI InChI=1S/C19H14Cl2N4OS/c1-24(13-5-3-2-4-6-13)16(26)10-15-17(19-22-7-8-27-19)23-18-14(21)9-12(20)11-25(15)18/h2-9,11H,10H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.44n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50210792
PNG
(CHEMBL3917316)
Show SMILES C(COc1ccccc1)NCC1CSC2(CCCCC2)S1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274261
PNG
(4-(6,8-Dichloro-3-(2-(dipropylamino)-2-oxoethyl)im...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OC(=O)CN)cc1
Show InChI InChI=1S/C23H26Cl2N4O3/c1-3-9-28(10-4-2)20(30)12-19-22(27-23-18(25)11-16(24)14-29(19)23)15-5-7-17(8-6-15)32-21(31)13-26/h5-8,11,14H,3-4,9-10,12-13,26H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.52n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50408728
PNG
(CHEMBL339816)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(N)cccn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H25ClN4O/c1-3-11-25(12-4-2)19(27)14-18-20(15-7-9-16(22)10-8-15)24-21-17(23)6-5-13-26(18)21/h5-10,13H,3-4,11-12,14,23H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Bari"A. Moro"

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in rat C6 cell membrane after 90 mins by radioligand binding assay


ACS Med Chem Lett 5: 685-9 (2014)


Article DOI: 10.1021/ml5000788
BindingDB Entry DOI: 10.7270/Q26D5VKG
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159093
PNG
(CHEMBL179432 | N,N-Dibutyl-2-[6-chloro-2-(4-chloro...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H27Cl2N3O/c1-3-5-13-27(14-6-4-2)22(29)15-20-23(17-7-9-18(24)10-8-17)26-21-12-11-19(25)16-28(20)21/h7-12,16H,3-6,13-15H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.69n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274350
PNG
(4-(6,8-Dichloro-3-(2-(dipropylamino)-2-oxoethyl)im...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(OC(=O)CCC(=O)OC)cc1
Show InChI InChI=1S/C26H29Cl2N3O5/c1-4-12-30(13-5-2)22(32)15-21-25(29-26-20(28)14-18(27)16-31(21)26)17-6-8-19(9-7-17)36-24(34)11-10-23(33)35-3/h6-9,14,16H,4-5,10-13,15H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.69n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159076
PNG
(CHEMBL180279 | N-Butyl-2-(6,8-dichloro-2-phenyl-im...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C20H21Cl2N3O/c1-3-4-10-24(2)18(26)12-17-19(14-8-6-5-7-9-14)23-20-16(22)11-15(21)13-25(17)20/h5-9,11,13H,3-4,10,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.70n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159086
PNG
(8-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid...)
Show SMILES CCC(C)N(C)C(=O)c1cc2cccc(-c3ccccc3Cl)c2cn1
Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)20-12-15-8-7-10-16(18(15)13-23-20)17-9-5-6-11-19(17)22/h5-14H,4H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.70n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50204648
PNG
(2-(6,8-dichloro-2-(thiazol-2-yl)H-imidazo[1,2-a]py...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1nccs1
Show InChI InChI=1S/C18H20Cl2N4OS/c1-3-6-23(7-4-2)15(25)10-14-16(18-21-5-8-26-18)22-17-13(20)9-12(19)11-24(14)17/h5,8-9,11H,3-4,6-7,10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.07n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50210791
PNG
(CHEMBL3901382)
Show SMILES COc1ccccc1OCCNCC1CSC2(CCCCC2)O1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159076
PNG
(CHEMBL180279 | N-Butyl-2-(6,8-dichloro-2-phenyl-im...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1
Show InChI InChI=1S/C20H21Cl2N3O/c1-3-4-10-24(2)18(26)12-17-19(14-8-6-5-7-9-14)23-20-16(22)11-15(21)13-25(17)20/h5-9,11,13H,3-4,10,12H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.20n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274352
PNG
(2-(2-(4-Aminophenyl)-6,8-dichloroimidazo[1,2-a]pyr...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(N)cc1
Show InChI InChI=1S/C21H24Cl2N4O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-16(24)8-6-14)25-21-17(23)11-15(22)13-27(18)21/h5-8,11,13H,3-4,9-10,12,24H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.22n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159075
PNG
(CHEMBL180210 | N-Butyl-2-[6,8-dichloro-2-(4-chloro...)
Show SMILES CCCCN(C)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C20H20Cl3N3O/c1-3-4-9-25(2)18(27)11-17-19(13-5-7-14(21)8-6-13)24-20-16(23)10-15(22)12-26(17)20/h5-8,10,12H,3-4,9,11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.5n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159089
PNG
(CHEMBL180523 | N,N-Dibutyl-2-[6,8-dichloro-2-(4-ch...)
Show SMILES CCCCN(CCCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H26Cl3N3O/c1-3-5-11-28(12-6-4-2)21(30)14-20-22(16-7-9-17(24)10-8-16)27-23-19(26)13-18(25)15-29(20)23/h7-10,13,15H,3-6,11-12,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.68n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50274352
PNG
(2-(2-(4-Aminophenyl)-6,8-dichloroimidazo[1,2-a]pyr...)
Show SMILES CCCN(CCC)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(N)cc1
Show InChI InChI=1S/C21H24Cl2N4O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-16(24)8-6-14)25-21-17(23)11-15(22)13-27(18)21/h5-8,11,13H,3-4,9-10,12,24H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.76n/an/an/an/an/an/an/an/a



Universita degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation counting


J Med Chem 51: 6876-88 (2008)


Article DOI: 10.1021/jm8006728
BindingDB Entry DOI: 10.7270/Q23B612K
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50210795
PNG
(CHEMBL3929328)
Show SMILES COc1ccccc1N1CCN(CC2CSC3(CCCCC3)S2)CC1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (Human))
BDBM50210790
PNG
(CHEMBL3981480)
Show SMILES COc1ccccc1OCCNCC1COC2(CCCCC2)O1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Modena e Reggio Emilia

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...


Eur J Med Chem 125: 435-452 (2017)


Article DOI: 10.1016/j.ejmech.2016.09.050
BindingDB Entry DOI: 10.7270/Q2BG2R46
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159106
PNG
(2-[6-Chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyri...)
Show SMILES CCCCCCN(CCCCCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C27H35Cl2N3O/c1-3-5-7-9-17-31(18-10-8-6-4-2)26(33)19-24-27(21-11-13-22(28)14-12-21)30-25-16-15-23(29)20-32(24)25/h11-16,20H,3-10,17-19H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.01n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159104
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES Clc1ccc(cc1)-c1nc2c(Cl)cc(Cl)cn2c1CC(=O)N1CCCCC1
Show InChI InChI=1S/C20H18Cl3N3O/c21-14-6-4-13(5-7-14)19-17(11-18(27)25-8-2-1-3-9-25)26-12-15(22)10-16(23)20(26)24-19/h4-7,10,12H,1-3,8-9,11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.10n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159105
PNG
(CHEMBL368040 | N-Butyl-2-(6,8-dichloro-2-phenyl-im...)
Show SMILES CCCCN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H23Cl2N3O/c1-2-3-14-29(20-12-8-5-9-13-20)23(31)16-22-24(18-10-6-4-7-11-18)28-25-21(27)15-19(26)17-30(22)25/h4-13,15,17H,2-3,14,16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.5n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159078
PNG
(CHEMBL179675 | N-Butyl-2-[6,8-dichloro-2-(4-chloro...)
Show SMILES CCCCN(C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C25H22Cl3N3O/c1-2-3-13-30(20-7-5-4-6-8-20)23(32)15-22-24(17-9-11-18(26)12-10-17)29-25-21(28)14-19(27)16-31(22)25/h4-12,14,16H,2-3,13,15H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.70n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159096
PNG
(CHEMBL178676 | N,N-Diallyl-2-[6,8-dichloro-2-(4-ch...)
Show SMILES Clc1ccc(cc1)-c1nc2c(Cl)cc(Cl)cn2c1CC(=O)N(CC=C)CC=C
Show InChI InChI=1S/C21H18Cl3N3O/c1-3-9-26(10-4-2)19(28)12-18-20(14-5-7-15(22)8-6-14)25-21-17(24)11-16(23)13-27(18)21/h3-8,11,13H,1-2,9-10,12H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.06n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159086
PNG
(8-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid...)
Show SMILES CCC(C)N(C)C(=O)c1cc2cccc(-c3ccccc3Cl)c2cn1
Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)20-12-15-8-7-10-16(18(15)13-23-20)17-9-5-6-11-19(17)22/h5-14H,4H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.27n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 348 total )  |  Next  |  Last  >>
Jump to: