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Compile Data Set for Download or QSAR

Found 492 hits with Last Name = 'dickson' and Initial = 'bm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194448
PNG
(CHEMBL3972289)
Show SMILES CCCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C45H70N6O8/c1-11-24-51(30(4)5)25-16-15-19-35(41(55)50-38(28-52)44(58)59-10)47-43(57)36(26-29(2)3)48-39(53)31(6)46-42(56)37(27-32-17-13-12-14-18-32)49-40(54)33-20-22-34(23-21-33)45(7,8)9/h12-14,17-18,20-23,29-31,35-38,52H,11,15-16,19,24-28H2,1-10H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t31-,35-,36-,37-,38-/s2
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n/an/a 32n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194466
PNG
(CHEMBL3958557)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C |r|
Show InChI InChI=1/C42H64N6O8/c1-27(2)24-33(40(54)44-32(18-14-15-23-48(7,8)9)38(52)47-35(26-49)41(55)56-10)45-36(50)28(3)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(4,5)6/h11-13,16-17,19-22,27-28,32-35,49H,14-15,18,23-26H2,1-10H3,(H4-,43,44,45,46,47,50,51,52,53,54)/p+1/t28-,32-,33-,34-,35-/s2
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n/an/a 35n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194475
PNG
(CHEMBL3889586)
Show SMILES CCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C44H68N6O8/c1-11-50(29(4)5)24-16-15-19-34(40(54)49-37(27-51)43(57)58-10)46-42(56)35(25-28(2)3)47-38(52)30(6)45-41(55)36(26-31-17-13-12-14-18-31)48-39(53)32-20-22-33(23-21-32)44(7,8)9/h12-14,17-18,20-23,28-30,34-37,51H,11,15-16,19,24-27H2,1-10H3,(H,45,55)(H,46,56)(H,47,52)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/s2
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n/an/a 35n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194259
PNG
(CHEMBL3939958)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t29-,33-,34-,35-,36-/s2
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n/an/a 37n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194476
PNG
(CHEMBL3942693)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)N(C)C |r|
Show InChI InChI=1/C44H69N7O7/c1-11-51(12-2)25-17-16-20-34(40(55)49-37(28-52)43(58)50(9)10)46-42(57)35(26-29(3)4)47-38(53)30(5)45-41(56)36(27-31-18-14-13-15-19-31)48-39(54)32-21-23-33(24-22-32)44(6,7)8/h13-15,18-19,21-24,29-30,34-37,52H,11-12,16-17,20,25-28H2,1-10H3,(H,45,56)(H,46,57)(H,47,53)(H,48,54)(H,49,55)/t30-,34-,35-,36-,37-/s2
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n/an/a 47n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194477
PNG
(CHEMBL3916023)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C49H77N7O10/c1-13-56(14-2)26-16-15-17-37(43(60)55-40(30-57)46(63)65-12)52-45(62)38(27-31(3)4)53-41(58)32(5)51-44(61)39(54-42(59)35-22-24-36(25-23-35)48(6,7)8)28-33-18-20-34(21-19-33)29-50-47(64)66-49(9,10)11/h18-25,31-32,37-40,57H,13-17,26-30H2,1-12H3,(H,50,64)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,55,60)/t32-,37-,38-,39-,40-/s2
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n/an/a 56n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194258
PNG
(CHEMBL3934881)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C42H64N6O8/c1-9-48(10-2)23-15-14-18-33(39(52)47-36(26-49)42(55)56-8)44-41(54)34(24-27(3)4)45-37(50)29(7)43-40(53)35(25-30-16-12-11-13-17-30)46-38(51)32-21-19-31(20-22-32)28(5)6/h11-13,16-17,19-22,27-29,33-36,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)/t29-,33-,34-,35-,36-/s2
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n/an/a 61n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194448
PNG
(CHEMBL3972289)
Show SMILES CCCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C45H70N6O8/c1-11-24-51(30(4)5)25-16-15-19-35(41(55)50-38(28-52)44(58)59-10)47-43(57)36(26-29(2)3)48-39(53)31(6)46-42(56)37(27-32-17-13-12-14-18-32)49-40(54)33-20-22-34(23-21-33)45(7,8)9/h12-14,17-18,20-23,29-31,35-38,52H,11,15-16,19,24-28H2,1-10H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t31-,35-,36-,37-,38-/s2
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n/an/a 62n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194458
PNG
(CHEMBL3987134)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CN)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H69N7O8/c1-10-51(11-2)23-13-12-14-34(40(55)50-37(27-52)43(58)59-9)47-42(57)35(24-28(3)4)48-38(53)29(5)46-41(56)36(25-30-15-17-31(26-45)18-16-30)49-39(54)32-19-21-33(22-20-32)44(6,7)8/h15-22,28-29,34-37,52H,10-14,23-27,45H2,1-9H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t29-,34-,35-,36-,37-/s2
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n/an/a 63n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194466
PNG
(CHEMBL3958557)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C |r|
Show InChI InChI=1/C42H64N6O8/c1-27(2)24-33(40(54)44-32(18-14-15-23-48(7,8)9)38(52)47-35(26-49)41(55)56-10)45-36(50)28(3)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(4,5)6/h11-13,16-17,19-22,27-28,32-35,49H,14-15,18,23-26H2,1-10H3,(H4-,43,44,45,46,47,50,51,52,53,54)/p+1/t28-,32-,33-,34-,35-/s2
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n/an/a 75n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194457
PNG
(CHEMBL3969494)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)NCCO |r|
Show InChI InChI=1/C41H64N6O6/c1-9-47(10-2)24-15-14-18-33(38(51)42-23-25-48)44-40(53)34(26-28(3)4)45-36(49)29(5)43-39(52)35(27-30-16-12-11-13-17-30)46-37(50)31-19-21-32(22-20-31)41(6,7)8/h11-13,16-17,19-22,28-29,33-35,48H,9-10,14-15,18,23-27H2,1-8H3,(H,42,51)(H,43,52)(H,44,53)(H,45,49)(H,46,50)/t29-,33-,34-,35-/s2
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n/an/a 75n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194458
PNG
(CHEMBL3987134)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CN)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H69N7O8/c1-10-51(11-2)23-13-12-14-34(40(55)50-37(27-52)43(58)59-9)47-42(57)35(24-28(3)4)48-38(53)29(5)46-41(56)36(25-30-15-17-31(26-45)18-16-30)49-39(54)32-19-21-33(22-20-32)44(6,7)8/h15-22,28-29,34-37,52H,10-14,23-27,45H2,1-9H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t29-,34-,35-,36-,37-/s2
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n/an/a 75n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194475
PNG
(CHEMBL3889586)
Show SMILES CCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C44H68N6O8/c1-11-50(29(4)5)24-16-15-19-34(40(54)49-37(27-51)43(57)58-10)46-42(56)35(25-28(2)3)47-38(52)30(6)45-41(55)36(26-31-17-13-12-14-18-31)48-39(53)32-20-22-33(23-21-32)44(7,8)9/h12-14,17-18,20-23,28-30,34-37,51H,11,15-16,19,24-27H2,1-10H3,(H,45,55)(H,46,56)(H,47,52)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/s2
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n/an/a 75n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194474
PNG
(CHEMBL3953637)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(CC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C41H62N6O8/c1-8-29-19-21-31(22-20-29)37(50)45-34(25-30-16-12-11-13-17-30)39(52)42-28(6)36(49)44-33(24-27(4)5)40(53)43-32(18-14-15-23-47(9-2)10-3)38(51)46-35(26-48)41(54)55-7/h11-13,16-17,19-22,27-28,32-35,48H,8-10,14-15,18,23-26H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t28-,32-,33-,34-,35-/s2
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n/an/a 81n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194259
PNG
(CHEMBL3939958)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t29-,33-,34-,35-,36-/s2
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n/an/a 83n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194447
PNG
(CHEMBL3978944)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H62N6O8/c1-7-50(8-2)23-15-14-20-35(41(54)49-38(28-51)44(57)58-6)47-43(56)36(24-29(3)4)48-40(53)30(5)45-42(55)37(26-31-16-10-9-11-17-31)46-39(52)27-32-21-22-33-18-12-13-19-34(33)25-32/h9-13,16-19,21-22,25,29-30,35-38,51H,7-8,14-15,20,23-24,26-28H2,1-6H3,(H,45,55)(H,46,52)(H,47,56)(H,48,53)(H,49,54)/t30-,35-,36-,37-,38-/s2
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n/an/a 84n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194477
PNG
(CHEMBL3916023)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C49H77N7O10/c1-13-56(14-2)26-16-15-17-37(43(60)55-40(30-57)46(63)65-12)52-45(62)38(27-31(3)4)53-41(58)32(5)51-44(61)39(54-42(59)35-22-24-36(25-23-35)48(6,7)8)28-33-18-20-34(21-19-33)29-50-47(64)66-49(9,10)11/h18-25,31-32,37-40,57H,13-17,26-30H2,1-12H3,(H,50,64)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,55,60)/t32-,37-,38-,39-,40-/s2
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n/an/a 98n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194474
PNG
(CHEMBL3953637)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(CC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C41H62N6O8/c1-8-29-19-21-31(22-20-29)37(50)45-34(25-30-16-12-11-13-17-30)39(52)42-28(6)36(49)44-33(24-27(4)5)40(53)43-32(18-14-15-23-47(9-2)10-3)38(51)46-35(26-48)41(54)55-7/h11-13,16-17,19-22,27-28,32-35,48H,8-10,14-15,18,23-26H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t28-,32-,33-,34-,35-/s2
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n/an/a 100n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194258
PNG
(CHEMBL3934881)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C42H64N6O8/c1-9-48(10-2)23-15-14-18-33(39(52)47-36(26-49)42(55)56-8)44-41(54)34(24-27(3)4)45-37(50)29(7)43-40(53)35(25-30-16-12-11-13-17-30)46-38(51)32-21-19-31(20-22-32)28(5)6/h11-13,16-17,19-22,27-29,33-36,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)/t29-,33-,34-,35-,36-/s2
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n/an/a 100n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194262
PNG
(CHEMBL3949885)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C42H61N7O8/c1-7-49(8-2)21-15-14-20-33(39(53)48-36(26-50)42(56)57-6)46-41(55)34(22-27(3)4)47-38(52)28(5)44-40(54)35(23-29-16-10-9-11-17-29)45-37(51)24-30-25-43-32-19-13-12-18-31(30)32/h9-13,16-19,25,27-28,33-36,43,50H,7-8,14-15,20-24,26H2,1-6H3,(H,44,54)(H,45,51)(H,46,55)(H,47,52)(H,48,53)/t28-,33-,34-,35-,36-/s2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194466
PNG
(CHEMBL3958557)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C |r|
Show InChI InChI=1/C42H64N6O8/c1-27(2)24-33(40(54)44-32(18-14-15-23-48(7,8)9)38(52)47-35(26-49)41(55)56-10)45-36(50)28(3)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(4,5)6/h11-13,16-17,19-22,27-28,32-35,49H,14-15,18,23-26H2,1-10H3,(H4-,43,44,45,46,47,50,51,52,53,54)/p+1/t28-,32-,33-,34-,35-/s2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194448
PNG
(CHEMBL3972289)
Show SMILES CCCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C45H70N6O8/c1-11-24-51(30(4)5)25-16-15-19-35(41(55)50-38(28-52)44(58)59-10)47-43(57)36(26-29(2)3)48-39(53)31(6)46-42(56)37(27-32-17-13-12-14-18-32)49-40(54)33-20-22-34(23-21-33)45(7,8)9/h12-14,17-18,20-23,29-31,35-38,52H,11,15-16,19,24-28H2,1-10H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t31-,35-,36-,37-,38-/s2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194471
PNG
(CHEMBL3943850)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(=O)OC)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C41H60N6O10/c1-8-47(9-2)22-14-13-17-31(37(51)46-34(25-48)41(55)57-7)43-39(53)32(23-26(3)4)44-35(49)27(5)42-38(52)33(24-28-15-11-10-12-16-28)45-36(50)29-18-20-30(21-19-29)40(54)56-6/h10-12,15-16,18-21,26-27,31-34,48H,8-9,13-14,17,22-25H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t27-,31-,32-,33-,34-/s2
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n/an/a 110n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194475
PNG
(CHEMBL3889586)
Show SMILES CCN(CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC)C(C)C |r|
Show InChI InChI=1/C44H68N6O8/c1-11-50(29(4)5)24-16-15-19-34(40(54)49-37(27-51)43(57)58-10)46-42(56)35(25-28(2)3)47-38(52)30(6)45-41(55)36(26-31-17-13-12-14-18-31)48-39(53)32-20-22-33(23-21-32)44(7,8)9/h12-14,17-18,20-23,28-30,34-37,51H,11,15-16,19,24-27H2,1-10H3,(H,45,55)(H,46,56)(H,47,52)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/s2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194260
PNG
(CHEMBL3973366)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H57F3N6O8/c1-7-49(8-2)21-13-12-16-30(36(53)48-33(24-50)39(56)57-6)45-38(55)31(22-25(3)4)46-34(51)26(5)44-37(54)32(23-27-14-10-9-11-15-27)47-35(52)28-17-19-29(20-18-28)40(41,42)43/h9-11,14-15,17-20,25-26,30-33,50H,7-8,12-13,16,21-24H2,1-6H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t26-,30-,31-,32-,33-/s2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194450
PNG
(CHEMBL3933207)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(O)=O |r|
Show InChI InChI=1/C42H64N6O8/c1-9-48(10-2)23-15-14-18-32(38(52)47-35(26-49)41(55)56)44-40(54)33(24-27(3)4)45-36(50)28(5)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(6,7)8/h11-13,16-17,19-22,27-28,32-35,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)(H,55,56)/t28-,32-,33-,34-,35-/s2
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n/an/a 130n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194476
PNG
(CHEMBL3942693)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)N(C)C |r|
Show InChI InChI=1/C44H69N7O7/c1-11-51(12-2)25-17-16-20-34(40(55)49-37(28-52)43(58)50(9)10)46-42(57)35(26-29(3)4)47-38(53)30(5)45-41(56)36(27-31-18-14-13-15-19-31)48-39(54)32-21-23-33(24-22-32)44(6,7)8/h13-15,18-19,21-24,29-30,34-37,52H,11-12,16-17,20,25-28H2,1-10H3,(H,45,56)(H,46,57)(H,47,53)(H,48,54)(H,49,55)/t30-,34-,35-,36-,37-/s2
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194259
PNG
(CHEMBL3939958)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C43H66N6O8/c1-10-49(11-2)24-16-15-19-33(39(53)48-36(27-50)42(56)57-9)45-41(55)34(25-28(3)4)46-37(51)29(5)44-40(54)35(26-30-17-13-12-14-18-30)47-38(52)31-20-22-32(23-21-31)43(6,7)8/h12-14,17-18,20-23,28-29,33-36,50H,10-11,15-16,19,24-27H2,1-9H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t29-,33-,34-,35-,36-/s2
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n/an/a 140n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194258
PNG
(CHEMBL3934881)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C42H64N6O8/c1-9-48(10-2)23-15-14-18-33(39(52)47-36(26-49)42(55)56-8)44-41(54)34(24-27(3)4)45-37(50)29(7)43-40(53)35(25-30-16-12-11-13-17-30)46-38(51)32-21-19-31(20-22-32)28(5)6/h11-13,16-17,19-22,27-29,33-36,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)/t29-,33-,34-,35-,36-/s2
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n/an/a 160n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194477
PNG
(CHEMBL3916023)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C49H77N7O10/c1-13-56(14-2)26-16-15-17-37(43(60)55-40(30-57)46(63)65-12)52-45(62)38(27-31(3)4)53-41(58)32(5)51-44(61)39(54-42(59)35-22-24-36(25-23-35)48(6,7)8)28-33-18-20-34(21-19-33)29-50-47(64)66-49(9,10)11/h18-25,31-32,37-40,57H,13-17,26-30H2,1-12H3,(H,50,64)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,55,60)/t32-,37-,38-,39-,40-/s2
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n/an/a 160n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194458
PNG
(CHEMBL3987134)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CN)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H69N7O8/c1-10-51(11-2)23-13-12-14-34(40(55)50-37(27-52)43(58)59-9)47-42(57)35(24-28(3)4)48-38(53)29(5)46-41(56)36(25-30-15-17-31(26-45)18-16-30)49-39(54)32-19-21-33(22-20-32)44(6,7)8/h15-22,28-29,34-37,52H,10-14,23-27,45H2,1-9H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t29-,34-,35-,36-,37-/s2
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n/an/a 170n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194474
PNG
(CHEMBL3953637)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(CC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C41H62N6O8/c1-8-29-19-21-31(22-20-29)37(50)45-34(25-30-16-12-11-13-17-30)39(52)42-28(6)36(49)44-33(24-27(4)5)40(53)43-32(18-14-15-23-47(9-2)10-3)38(51)46-35(26-48)41(54)55-7/h11-13,16-17,19-22,27-28,32-35,48H,8-10,14-15,18,23-26H2,1-7H3,(H,42,52)(H,43,53)(H,44,49)(H,45,50)(H,46,51)/t28-,32-,33-,34-,35-/s2
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n/an/a 190n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194261
PNG
(CHEMBL3970686)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H68N6O8/c1-10-50(11-2)24-16-15-19-34(40(54)49-37(28-51)43(57)58-9)47-42(56)35(25-29(3)4)48-39(53)30(5)45-41(55)36(26-31-17-13-12-14-18-31)46-38(52)27-32-20-22-33(23-21-32)44(6,7)8/h12-14,17-18,20-23,29-30,34-37,51H,10-11,15-16,19,24-28H2,1-9H3,(H,45,55)(H,46,52)(H,47,56)(H,48,53)(H,49,54)/t30-,34-,35-,36-,37-/s2
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n/an/a 200n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194457
PNG
(CHEMBL3969494)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)NCCO |r|
Show InChI InChI=1/C41H64N6O6/c1-9-47(10-2)24-15-14-18-33(38(51)42-23-25-48)44-40(53)34(26-28(3)4)45-36(49)29(5)43-39(52)35(27-30-16-12-11-13-17-30)46-37(50)31-19-21-32(22-20-31)41(6,7)8/h11-13,16-17,19-22,28-29,33-35,48H,9-10,14-15,18,23-27H2,1-8H3,(H,42,51)(H,43,52)(H,44,53)(H,45,49)(H,46,50)/t29-,33-,34-,35-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194257
PNG
(CHEMBL3925993)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(C)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O8/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(23-26(3)4)43-35(48)28(6)41-38(51)33(24-29-15-11-10-12-16-29)44-36(49)30-20-18-27(5)19-21-30/h10-12,15-16,18-21,26,28,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194260
PNG
(CHEMBL3973366)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H57F3N6O8/c1-7-49(8-2)21-13-12-16-30(36(53)48-33(24-50)39(56)57-6)45-38(55)31(22-25(3)4)46-34(51)26(5)44-37(54)32(23-27-14-10-9-11-15-27)47-35(52)28-17-19-29(20-18-28)40(41,42)43/h9-11,14-15,17-20,25-26,30-33,50H,7-8,12-13,16,21-24H2,1-6H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t26-,30-,31-,32-,33-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194450
PNG
(CHEMBL3933207)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(O)=O |r|
Show InChI InChI=1/C42H64N6O8/c1-9-48(10-2)23-15-14-18-32(38(52)47-35(26-49)41(55)56)44-40(54)33(24-27(3)4)45-36(50)28(5)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(6,7)8/h11-13,16-17,19-22,27-28,32-35,49H,9-10,14-15,18,23-26H2,1-8H3,(H,43,53)(H,44,54)(H,45,50)(H,46,51)(H,47,52)(H,55,56)/t28-,32-,33-,34-,35-/s2
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n/an/a 240n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194462
PNG
(CHEMBL3898460)
Show SMILES CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN(CC)CC)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H68N6O8/c1-10-33(45-42(56)36(27-30-18-14-13-15-19-30)47-38(52)31-21-23-32(24-22-31)44(6,7)8)39(53)48-35(26-29(4)5)41(55)46-34(20-16-17-25-50(11-2)12-3)40(54)49-37(28-51)43(57)58-9/h13-15,18-19,21-24,29,33-37,51H,10-12,16-17,20,25-28H2,1-9H3,(H,45,56)(H,46,55)(H,47,52)(H,48,53)(H,49,54)/t33-,34-,35-,36-,37-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromobox protein homolog 7


(Homo sapiens (Human))
BDBM50194469
PNG
(CHEMBL3937936)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(OC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O9/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)55-7)42-39(52)32(23-26(3)4)43-35(48)27(5)41-38(51)33(24-28-15-11-10-12-16-28)44-36(49)29-18-20-30(54-6)21-19-29/h10-12,15-16,18-21,26-27,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t27-,31-,32-,33-,34-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194469
PNG
(CHEMBL3937936)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(OC)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O9/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)55-7)42-39(52)32(23-26(3)4)43-35(48)27(5)41-38(51)33(24-28-15-11-10-12-16-28)44-36(49)29-18-20-30(54-6)21-19-29/h10-12,15-16,18-21,26-27,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t27-,31-,32-,33-,34-/s2
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n/an/a 260n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194257
PNG
(CHEMBL3925993)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(C)cc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O8/c1-8-46(9-2)22-14-13-17-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(23-26(3)4)43-35(48)28(6)41-38(51)33(24-29-15-11-10-12-16-29)44-36(49)30-20-18-27(5)19-21-30/h10-12,15-16,18-21,26,28,31-34,47H,8-9,13-14,17,22-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/s2
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n/an/a 280n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194256
PNG
(CHEMBL3944916)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(C)c1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O8/c1-8-46(9-2)21-14-13-20-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(22-26(3)4)43-35(48)28(6)41-38(51)33(24-29-17-11-10-12-18-29)44-36(49)30-19-15-16-27(5)23-30/h10-12,15-19,23,26,28,31-34,47H,8-9,13-14,20-22,24-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/s2
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n/an/a 340n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194255
PNG
(CHEMBL3935965)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C39H58N6O8/c1-7-45(8-2)22-16-15-21-30(36(49)44-33(25-46)39(52)53-6)41-38(51)31(23-26(3)4)42-34(47)27(5)40-37(50)32(24-28-17-11-9-12-18-28)43-35(48)29-19-13-10-14-20-29/h9-14,17-20,26-27,30-33,46H,7-8,15-16,21-25H2,1-6H3,(H,40,50)(H,41,51)(H,42,47)(H,43,48)(H,44,49)/t27-,30-,31-,32-,33-/s2
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n/an/a 340n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194476
PNG
(CHEMBL3942693)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)N(C)C |r|
Show InChI InChI=1/C44H69N7O7/c1-11-51(12-2)25-17-16-20-34(40(55)49-37(28-52)43(58)50(9)10)46-42(57)35(26-29(3)4)47-38(53)30(5)45-41(56)36(27-31-18-14-13-15-19-31)48-39(54)32-21-23-33(24-22-32)44(6,7)8/h13-15,18-19,21-24,29-30,34-37,52H,11-12,16-17,20,25-28H2,1-10H3,(H,45,56)(H,46,57)(H,47,53)(H,48,54)(H,49,55)/t30-,34-,35-,36-,37-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194457
PNG
(CHEMBL3969494)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)NCCO |r|
Show InChI InChI=1/C41H64N6O6/c1-9-47(10-2)24-15-14-18-33(38(51)42-23-25-48)44-40(53)34(26-28(3)4)45-36(49)29(5)43-39(52)35(27-30-16-12-11-13-17-30)46-37(50)31-19-21-32(22-20-31)41(6,7)8/h11-13,16-17,19-22,28-29,33-35,48H,9-10,14-15,18,23-27H2,1-8H3,(H,42,51)(H,43,52)(H,44,53)(H,45,49)(H,46,50)/t29-,33-,34-,35-/s2
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n/an/a 410n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194387
PNG
(CHEMBL3986571)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN(C)C(=O)c1ccccc1 |r|
Show InChI InChI=1/C41H61N7O9/c1-27(2)23-32(39(54)44-31(21-15-16-22-48(5,6)7)37(52)46-34(26-49)41(56)57-8)45-36(51)28(3)42-38(53)33(24-29-17-11-9-12-18-29)43-35(50)25-47(4)40(55)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,49H,15-16,21-26H2,1-8H3,(H4-,42,43,44,45,46,50,51,52,53,54)/p+1/t28-,31-,32-,33-,34-/s2
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University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
E3 SUMO-protein ligase CBX4


(Homo sapiens (Human))
BDBM50194260
PNG
(CHEMBL3973366)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H57F3N6O8/c1-7-49(8-2)21-13-12-16-30(36(53)48-33(24-50)39(56)57-6)45-38(55)31(22-25(3)4)46-34(51)26(5)44-37(54)32(23-27-14-10-9-11-15-27)47-35(52)28-17-19-29(20-18-28)40(41,42)43/h9-11,14-15,17-20,25-26,30-33,50H,7-8,12-13,16,21-24H2,1-6H3,(H,44,54)(H,45,55)(H,46,51)(H,47,52)(H,48,53)/t26-,30-,31-,32-,33-/s2
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n/an/a 480n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX4 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194462
PNG
(CHEMBL3898460)
Show SMILES CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN(CC)CC)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C44H68N6O8/c1-10-33(45-42(56)36(27-30-18-14-13-15-19-30)47-38(52)31-21-23-32(24-22-31)44(6,7)8)39(53)48-35(26-29(4)5)41(55)46-34(20-16-17-25-50(11-2)12-3)40(54)49-37(28-51)43(57)58-9/h13-15,18-19,21-24,29,33-37,51H,10-12,16-17,20,25-28H2,1-9H3,(H,45,56)(H,46,55)(H,47,52)(H,48,53)(H,49,54)/t33-,34-,35-,36-,37-/s2
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n/an/a 500n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194468
PNG
(CHEMBL3966329)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r|
Show InChI InChI=1/C42H61N7O9/c1-28(2)24-33(41(56)46-32(39(54)48-35(27-50)42(57)58-4)20-12-15-23-49-21-13-7-14-22-49)47-37(52)29(3)44-40(55)34(25-30-16-8-5-9-17-30)45-36(51)26-43-38(53)31-18-10-6-11-19-31/h5-6,8-11,16-19,28-29,32-35,50H,7,12-15,20-27H2,1-4H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t29-,32-,33-,34-,35-/s2
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n/an/a 540n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
Chromodomain Y-like protein 2


(Homo sapiens (Human))
BDBM50194473
PNG
(CHEMBL3916999)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1/C40H60N6O8/c1-8-46(9-2)22-16-15-21-31(37(50)45-34(25-47)40(53)54-7)42-39(52)32(23-26(3)4)43-35(48)28(6)41-38(51)33(24-29-18-11-10-12-19-29)44-36(49)30-20-14-13-17-27(30)5/h10-14,17-20,26,28,31-34,47H,8-9,15-16,21-25H2,1-7H3,(H,41,51)(H,42,52)(H,43,48)(H,44,49)(H,45,50)/t28-,31-,32-,33-,34-/s2
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n/an/a 560n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CDYL2 chromodomain (1 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair
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