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Compile Data Set for Download or QSAR

Found 75 hits with Last Name = 'dobos' and Initial = 'j'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389576
PNG
(N-{6-bromo-2-[(E)-2-(4- methoxyphenyl)vinyl]quinaz...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 74n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389583
PNG
(N-{2-[(E)-2-(4- methoxyphenyl)vinyl]quinazolin-4- ...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 134n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389615
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 246n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389591
PNG
(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 258n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50396483
PNG
(PLX-4032 | RG 7204 | Ro 5185426 | US9388165, Refer...)
Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F
Show InChI InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)
PDB
MMDB

NCI pathway
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PubMed
n/an/a 280n/an/an/an/an/an/a



Semmelweis University

Curated by ChEMBL


Assay Description
Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...


Eur J Med Chem 108: 623-43 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60QX5
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389604
PNG
(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylsulfonyl)phen...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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PC sid
UniChem
Article
n/an/a 326n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389608
PNG
(N'-{6-chloro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 412n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389616
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 440n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389586
PNG
(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
n/an/a 461n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389611
PNG
(N'-{6-fluoro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 582n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389574
PNG
(N'-{2-[(E)-2-(4- fluorophenyl)vinyl]quinazolin-4-y...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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GoogleScholar
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PC cid
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UniChem
Article
n/an/a 811n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389613
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 873n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389612
PNG
(N,N-diethyl-N'-{6-fluoro-2-[(E)-2-(4- isopropylphe...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 874n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389585
PNG
(N,N-dimethyl-N'-{2-[(E)-2-(2- thienyl)vinyl]benzo[...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 950n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50396483
PNG
(PLX-4032 | RG 7204 | Ro 5185426 | US9388165, Refer...)
Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F
Show InChI InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)
PDB
MMDB

NCI pathway
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KEGG

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PDB
UniChem
PDB
PubMed
n/an/a 1.14E+3n/an/an/an/an/an/a



Semmelweis University

Curated by ChEMBL


Assay Description
Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...


Eur J Med Chem 108: 623-43 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60QX5
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389610
PNG
(N'-{6-fluoro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 1.26E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389602
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylthio)phenyl]vinyl...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 1.26E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389606
PNG
(N'-{6-chloro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
n/an/a 1.27E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389559
PNG
(N'-{6-bromo-2-[(E)-2-(4- methoxyphenyl)vinyl]quina...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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UniChem
Article
n/an/a 1.39E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389609
PNG
(N'-{6-chloro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 1.40E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389558
PNG
(N'-{6-bromo-2-[(E)-2-(4- methoxyphenyl)vinyl]quina...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
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UniChem
Article
n/an/a 1.42E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389590
PNG
(N,N-diethyl-N'-{2-[(E)-2-(4- isopropylphenyl)vinyl...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 1.51E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389603
PNG
(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylsulfonyl)phen...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 1.51E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389562
PNG
(N'-{6-bromo-2-[(E)-2-(4- fluorophenyl)vinyl]quinaz...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
n/an/a 1.55E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389582
PNG
(N,N-dimethyl-N'-{2-[(E)-2-(2- thienyl)vinyl]benzo[...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem
Article
n/an/a 1.64E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389581
PNG
(N'-{6-chloro-2-[(E)-2-(3,4- difluorophenyl)vinyl]q...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
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UniChem
Article
n/an/a 1.70E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389578
PNG
(N,N-diethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]vi...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
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UniChem
Article
n/an/a 1.76E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389554
PNG
(N'-{6-chloro-2-[(E)-2-(4- methoxyphenyl)vinyl]quin...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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UniChem
Article
n/an/a 1.91E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389560
PNG
(N'-{6-bromo-2-[(E)-2-(4- methoxyphenyl)vinyl]quina...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
n/an/a 1.96E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389614
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylsulfonyl)phenyl]v...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
n/an/a 1.98E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389573
PNG
(N'-{6-bromo-2-[(E)-2-(3,4- difluorophenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
n/an/a 2.00E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389589
PNG
(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
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UniChem
Article
n/an/a 2.02E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389575
PNG
(N,N-diethyl-N'-{2-[(E)-2-(4- fluorophenyl)vinyl]qu...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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UniChem
Article
n/an/a 2.12E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389567
PNG
(N'-{6-chloro-2-[(E)-2-(4- fluorophenyl)vinyl]quina...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
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UniChem
Article
n/an/a 2.26E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389565
PNG
(N'-{6-bromo-2-[(E)-2-(4- fluorophenyl)vinyl]quinaz...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
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UniChem
Article
n/an/a 2.28E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389595
PNG
(N'-{6-chloro-2-[(E)-2-(2- thienyl)vinyl]quinazolin...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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UniChem
Article
n/an/a 2.31E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389584
PNG
(N,N-diethyl-N'-{2-[(E)-2-(2- thienyl)vinyl]benzo[g...)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
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UniChem
Article
n/an/a 2.33E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389599
PNG
(N'-(6-chloro-2-{(E)-2-[4- (methylthio)phenyl]vinyl...)
PDB
MMDB

KEGG

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UniChem
Article
n/an/a 2.39E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389566
PNG
(N'-{6-chloro-2-[(E)-2-(4- fluorophenyl)vinyl]quina...)
PDB
MMDB

KEGG

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Article
n/an/a 2.39E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389594
PNG
(N'-{6-chloro-2-[(E)-2-(2- thienyl)vinyl]quinazolin...)
PDB
MMDB

KEGG

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n/an/a 2.93E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389607
PNG
(N'-{6-chloro-2-[(E)-2-(4- isopropylphenyl)vinyl]qu...)
PDB
MMDB

KEGG

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n/an/a 2.97E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389563
PNG
(N'-{2-[(E)-2-(4- fluorophenyl)vinyl]quinazolin-4-y...)
PDB
MMDB

KEGG

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n/an/a 3.08E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389588
PNG
(N'-{2-[(E)-2-(3,4- difluorophenyl)vinyl]quinazolin...)
PDB
MMDB

KEGG

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n/an/a 3.25E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389577
PNG
(N-[3-({6-bromo-2-[(E)-2-(4- methoxyphenyl)vinyl]qu...)
PDB
MMDB

KEGG

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n/an/a 3.70E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389605
PNG
(2-{(E)-2-[4- (methylsulfonyl)phenyl]vinyl}-N- prop...)
PDB
MMDB

KEGG

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n/an/a 3.82E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389568
PNG
(N'-{6-fluoro-2-[(E)-2-(4- fluorophenyl)vinyl]quina...)
PDB
MMDB

KEGG

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Article
n/an/a 4.20E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389579
PNG
(N,N-dimethyl-N'-(2-{(E)-2-[4- (methylthio)phenyl]v...)
PDB
MMDB

KEGG

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Article
n/an/a 4.50E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389569
PNG
(N,N-diethyl-N'-{6-fluoro-2-[(E)-2-(4- fluorophenyl...)
PDB
MMDB

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n/an/a 4.76E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase B-raf


(Homo sapiens (Human))
BDBM50146591
PNG
(CHEMBL3763692)
Show SMILES Fc1ccc(cc1C(F)(F)F)C(=O)Nc1nccn2c(cnc12)-c1cccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)c1
Show InChI InChI=1S/C28H16ClF7N6O2/c29-20-6-5-17(12-18(20)27(31,32)33)40-26(44)39-16-3-1-2-14(10-16)22-13-38-24-23(37-8-9-42(22)24)41-25(43)15-4-7-21(30)19(11-15)28(34,35)36/h1-13H,(H,37,41,43)(H2,39,40,44)
PDB
MMDB

NCI pathway
Reactome pathway
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n/an/a 5.01E+3n/an/an/an/an/an/a



Semmelweis University

Curated by ChEMBL


Assay Description
Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...


Eur J Med Chem 108: 623-43 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60QX5
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor FLT3


(Homo sapiens (Human))
BDBM389561
PNG
(N'-{2-[(E)-2-(4- methoxyphenyl)vinyl]quinazolin-4-...)
PDB
MMDB

KEGG

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n/an/a 5.11E+3n/an/an/an/an/an/a



Georgia Institute of Technology





J Med Chem 52: 456-68 (2009)


Article DOI: 10.1021/jm801128g
More data for this
Ligand-Target Pair
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