new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 818 hits with Last Name = 'dong' and Initial = 'y'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305990
PNG
(CHEMBL596388 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES CCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C21H23ClF4N2O6S3/c1-2-20(14-27-37(33,34)21(24,25)26)9-11-28(12-10-20)36(31,32)18-8-7-15(22)13-19(18)35(29,30)17-6-4-3-5-16(17)23/h3-8,13,27H,2,9-12,14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.200n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305989
PNG
(CHEMBL596387 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES CC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C20H21ClF4N2O6S3/c1-19(13-26-36(32,33)20(23,24)25)8-10-27(11-9-19)35(30,31)17-7-6-14(21)12-18(17)34(28,29)16-5-3-2-4-15(16)22/h2-7,12,26H,8-11,13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.390n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306002
PNG
(CHEMBL595705 | N-(6-(5-chloro-2-(4-methoxyphenylsu...)
Show SMILES COc1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1
Show InChI InChI=1S/C21H22ClF3N2O7S3/c1-34-15-3-5-16(6-4-15)35(28,29)17-7-2-14(22)12-18(17)36(30,31)27-10-8-20(9-11-27)13-19(20)26-37(32,33)21(23,24)25/h2-7,12,19,26H,8-11,13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.650n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50211605
PNG
((S)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Show SMILES C[C@H](NS(=O)(=O)C(F)(F)F)c1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C21H16ClF4NO6S3/c1-13(27-36(32,33)21(24,25)26)14-6-9-16(10-7-14)34(28,29)19-11-8-15(22)12-20(19)35(30,31)18-5-3-2-4-17(18)23/h2-13,27H,1H3/t13-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.700n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306008
PNG
(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)-5-(...)
Show SMILES FC(F)(F)Oc1ccc(c(c1)S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C20H19F6N3O7S3/c21-19(22,23)36-13-4-5-14(37(30,31)17-3-1-2-8-27-17)15(11-13)38(32,33)29-9-6-18(7-10-29)12-16(18)28-39(34,35)20(24,25)26/h1-5,8,11,16,28H,6-7,9-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.900n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306000
PNG
(CHEMBL596133 | N-(6-(5-chloro-2-(2-fluorophenylsul...)
Show SMILES CS(=O)(=O)NC1CC11CCN(CC1)S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C20H22ClFN2O6S3/c1-31(25,26)23-19-13-20(19)8-10-24(11-9-20)33(29,30)18-12-14(21)6-7-17(18)32(27,28)16-5-3-2-4-15(16)22/h2-7,12,19,23H,8-11,13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306017
PNG
(CHEMBL604704 | N-((1R,5S,6s)-3-(4-chloro-2-(2-fluo...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1C[C@H]2[C@@H](C1)[C@@H]2NS(=O)(=O)C(F)(F)F |r|
Show InChI InChI=1S/C18H15ClF4N2O6S3/c19-10-5-6-15(16(7-10)32(26,27)14-4-2-1-3-13(14)20)33(28,29)25-8-11-12(9-25)17(11)24-34(30,31)18(21,22)23/h1-7,11-12,17,24H,8-9H2/t11-,12+,17+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306007
PNG
(CHEMBL592896 | N-(6-(5-chloro-2-(pyridin-2-ylsulfo...)
Show SMILES FC(F)(F)S(=O)(=O)NC1CC11CCN(CC1)S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C19H19ClF3N3O6S3/c20-13-4-5-14(33(27,28)17-3-1-2-8-24-17)15(11-13)34(29,30)26-9-6-18(7-10-26)12-16(18)25-35(31,32)19(21,22)23/h1-5,8,11,16,25H,6-7,9-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306016
PNG
(CHEMBL596579 | N-(6-(4-chloro-2-(2-fluorophenylsul...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1
Show InChI InChI=1S/C20H19ClF4N2O6S3/c21-13-5-6-16(17(11-13)34(28,29)15-4-2-1-3-14(15)22)35(30,31)27-9-7-19(8-10-27)12-18(19)26-36(32,33)20(23,24)25/h1-6,11,18,26H,7-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.70n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306003
PNG
(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Show SMILES Fc1ccccc1S(=O)(=O)c1ccc(cc1S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1)C(F)(F)F
Show InChI InChI=1S/C21H19F7N2O6S3/c22-14-3-1-2-4-15(14)37(31,32)16-6-5-13(20(23,24)25)11-17(16)38(33,34)30-9-7-19(8-10-30)12-18(19)29-39(35,36)21(26,27)28/h1-6,11,18,29H,7-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305993
PNG
(CHEMBL594300 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES OCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C20H21ClF4N2O7S3/c21-14-5-6-17(18(11-14)35(29,30)16-4-2-1-3-15(16)22)36(31,32)27-9-7-19(13-28,8-10-27)12-26-37(33,34)20(23,24)25/h1-6,11,26,28H,7-10,12-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306005
PNG
(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Show SMILES Fc1ccccc1S(=O)(=O)c1ccc(OC(F)(F)F)cc1S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1
Show InChI InChI=1S/C21H19F7N2O7S3/c22-14-3-1-2-4-15(14)38(31,32)16-6-5-13(37-20(23,24)25)11-17(16)39(33,34)30-9-7-19(8-10-30)12-18(19)29-40(35,36)21(26,27)28/h1-6,11,18,29H,7-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161407
PNG
(CHEMBL178447 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.30n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161407
PNG
(CHEMBL178447 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.30n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306004
PNG
(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)-5-(...)
Show SMILES FC(F)(F)c1ccc(c(c1)S(=O)(=O)N1CCC2(CC2NS(=O)(=O)C(F)(F)F)CC1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C20H19F6N3O6S3/c21-19(22,23)13-4-5-14(36(30,31)17-3-1-2-8-27-17)15(11-13)37(32,33)29-9-6-18(7-10-29)12-16(18)28-38(34,35)20(24,25)26/h1-5,8,11,16,28H,6-7,9-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305994
PNG
(CHEMBL593595 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES CC(O)C1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C21H23ClF4N2O7S3/c1-14(29)20(13-27-38(34,35)21(24,25)26)8-10-28(11-9-20)37(32,33)18-7-6-15(22)12-19(18)36(30,31)17-5-3-2-4-16(17)23/h2-7,12,14,27,29H,8-11,13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305991
PNG
(CHEMBL595481 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H25ClF4N2O6S3/c1-2-9-21(15-28-38(34,35)22(25,26)27)10-12-29(13-11-21)37(32,33)19-8-7-16(23)14-20(19)36(30,31)18-6-4-3-5-17(18)24/h3-8,14,28H,2,9-13,15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.40n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306006
PNG
(CHEMBL603321 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
Show InChI InChI=1S/C19H19ClF4N2O6S3/c20-14-5-6-17(18(11-14)33(27,28)16-4-2-1-3-15(16)21)34(29,30)26-9-7-13(8-10-26)12-25-35(31,32)19(22,23)24/h1-6,11,13,25H,7-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
5.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306018
PNG
(CHEMBL595460 | N-(((3R,4S)-1-(4-chloro-2-(2-fluoro...)
Show SMILES C[C@H]1CN(CC[C@@H]1CNS(=O)(=O)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F |r|
Show InChI InChI=1S/C20H21ClF4N2O6S3/c1-13-12-27(9-8-14(13)11-26-36(32,33)20(23,24)25)35(30,31)18-7-6-15(21)10-19(18)34(28,29)17-5-3-2-4-16(17)22/h2-7,10,13-14,26H,8-9,11-12H2,1H3/t13-,14+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Macaca mulatta)
BDBM50161407
PNG
(CHEMBL178447 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES OC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H31Cl2N3O2/c29-25-5-3-19(15-26(25)30)14-20-7-11-33(17-23(20)18-34)24-8-12-32(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-31-27/h1-6,10,15-16,20,23-24,34H,7-9,11-14,17-18H2/t20-,23+/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
7.20n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against monkey CC chemokine receptor 3


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305995
PNG
(CHEMBL593596 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1CCC(F)(CNS(=O)(=O)C(F)(F)F)CC1
Show InChI InChI=1S/C19H18ClF5N2O6S3/c20-13-5-6-16(17(11-13)34(28,29)15-4-2-1-3-14(15)21)35(30,31)27-9-7-18(22,8-10-27)12-26-36(32,33)19(23,24)25/h1-6,11,26H,7-10,12H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306019
PNG
((+/-)-N-(((2S)-1-(4-chloro-2-(2-fluorophenylsulfon...)
Show SMILES C[C@H]1CC(CNS(=O)(=O)C(F)(F)F)CCN1S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F |r|
Show InChI InChI=1S/C20H21ClF4N2O6S3/c1-13-10-14(12-26-36(32,33)20(23,24)25)8-9-27(13)35(30,31)18-7-6-15(21)11-19(18)34(28,29)17-5-3-2-4-16(17)22/h2-7,11,13-14,26H,8-10,12H2,1H3/t13-,14?/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
8n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306001
PNG
(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)phen...)
Show SMILES FC(F)(F)S(=O)(=O)NC1CC11CCN(CC1)S(=O)(=O)c1ccccc1S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C19H20F3N3O6S3/c20-19(21,22)34(30,31)24-16-13-18(16)8-11-25(12-9-18)33(28,29)15-6-2-1-5-14(15)32(26,27)17-7-3-4-10-23-17/h1-7,10,16,24H,8-9,11-13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
11n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161419
PNG
(CHEMBL178818 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(12-8-21(27)15-19-4-6-24(29)25(30)16-19)23-9-13-32(14-10-23)28(34)22-5-7-26-20(17-22)3-2-11-31-26/h2-7,11,16-17,21,23,27H,8-10,12-15,18H2,1H3/t21-,27-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
11n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161419
PNG
(CHEMBL178818 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(12-8-21(27)15-19-4-6-24(29)25(30)16-19)23-9-13-32(14-10-23)28(34)22-5-7-26-20(17-22)3-2-11-31-26/h2-7,11,16-17,21,23,27H,8-10,12-15,18H2,1H3/t21-,27-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
11n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161432
PNG
(CHEMBL181273 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2cccnc2n1
Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-25-17-33(12-8-20(25)15-18-4-6-22(28)23(29)16-18)21-9-13-32(14-10-21)27(34)24-7-5-19-3-2-11-30-26(19)31-24/h2-7,11,16,20-21,25H,8-10,12-15,17H2,1H3/t20-,25-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
15n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161420
PNG
(CHEMBL362040 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cccc2cccnc12
Show InChI InChI=1S/C28H31Cl2N3O2/c1-35-26-18-33(13-9-21(26)16-19-7-8-24(29)25(30)17-19)22-10-14-32(15-11-22)28(34)23-6-2-4-20-5-3-12-31-27(20)23/h2-8,12,17,21-22,26H,9-11,13-16,18H2,1H3/t21-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
18n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161439
PNG
(CHEMBL181034 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1nccc2ccccc12
Show InChI InChI=1S/C28H31Cl2N3O2/c1-35-26-18-33(13-9-21(26)16-19-6-7-24(29)25(30)17-19)22-10-14-32(15-11-22)28(34)27-23-5-3-2-4-20(23)8-12-31-27/h2-8,12,17,21-22,26H,9-11,13-16,18H2,1H3/t21-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
20n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305992
PNG
(CHEMBL605932 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES CC(C)C1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C22H25ClF4N2O6S3/c1-15(2)21(14-28-38(34,35)22(25,26)27)9-11-29(12-10-21)37(32,33)19-8-7-16(23)13-20(19)36(30,31)18-6-4-3-5-17(18)24/h3-8,13,15,28H,9-12,14H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
21n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161430
PNG
(CHEMBL178887 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES Clc1ccc(C[C@H]2CCN(C[C@H]2C=C)C2CCN(CC2)C(=O)c2ccc3ncccc3c2)cc1Cl
Show InChI InChI=1S/C29H31Cl2N3O/c1-2-21-19-34(13-9-22(21)16-20-5-7-26(30)27(31)17-20)25-10-14-33(15-11-25)29(35)24-6-8-28-23(18-24)4-3-12-32-28/h2-8,12,17-18,21-22,25H,1,9-11,13-16,19H2/t21-,22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
23n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161418
PNG
(CHEMBL180621 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccnc2ccccc12
Show InChI InChI=1S/C28H31Cl2N3O2/c1-35-27-18-33(13-9-20(27)16-19-6-7-24(29)25(30)17-19)21-10-14-32(15-11-21)28(34)23-8-12-31-26-5-3-2-4-22(23)26/h2-8,12,17,20-21,27H,9-11,13-16,18H2,1H3/t20-,27-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
26n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161423
PNG
(CHEMBL178136 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C29H33Cl2N3O/c1-2-21-19-34(13-9-22(21)16-20-5-7-26(30)27(31)17-20)25-10-14-33(15-11-25)29(35)24-6-8-28-23(18-24)4-3-12-32-28/h3-8,12,17-18,21-22,25H,2,9-11,13-16,19H2,1H3/t21-,22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
29n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161421
PNG
(CHEMBL362649 | [4-(3,4-Dichloro-benzyl)-[1,4'']bip...)
Show SMILES Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccc3ncccc3c2)cc1Cl
Show InChI InChI=1S/C27H29Cl2N3O/c28-24-5-3-20(17-25(24)29)16-19-7-12-31(13-8-19)23-9-14-32(15-10-23)27(33)22-4-6-26-21(18-22)2-1-11-30-26/h1-6,11,17-19,23H,7-10,12-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
30n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161422
PNG
(CHEMBL181379 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CCO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C29H33Cl2N3O2/c1-2-36-28-19-34(13-9-22(28)16-20-5-7-25(30)26(31)17-20)24-10-14-33(15-11-24)29(35)23-6-8-27-21(18-23)4-3-12-32-27/h3-8,12,17-18,22,24,28H,2,9-11,13-16,19H2,1H3/t22-,28-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
33n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161424
PNG
(CHEMBL181137 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnc2ccccc2n1
Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-8-19(26)14-18-6-7-21(28)22(29)15-18)20-9-12-32(13-10-20)27(34)25-16-30-23-4-2-3-5-24(23)31-25/h2-7,15-16,19-20,26H,8-14,17H2,1H3/t19-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
34n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161429
PNG
(CHEMBL179490 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2cnccc2n1
Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-7-19(26)14-18-2-4-22(28)23(29)15-18)21-8-12-32(13-9-21)27(34)25-5-3-20-16-30-10-6-24(20)31-25/h2-6,10,15-16,19,21,26H,7-9,11-14,17H2,1H3/t19-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
35n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50305996
PNG
(CHEMBL593838 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)(CC1)C#N
Show InChI InChI=1S/C20H18ClF4N3O6S3/c21-14-5-6-17(18(11-14)35(29,30)16-4-2-1-3-15(16)22)36(31,32)28-9-7-19(12-26,8-10-28)13-27-37(33,34)20(23,24)25/h1-6,11,27H,7-10,13H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
37.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161443
PNG
(CHEMBL180813 | [4-(3,4-Dichloro-benzyl)-[1,4'']bip...)
Show SMILES Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2ccnc3ccccc23)cc1Cl
Show InChI InChI=1S/C27H29Cl2N3O/c28-24-6-5-20(18-25(24)29)17-19-8-13-31(14-9-19)21-10-15-32(16-11-21)27(33)23-7-12-30-26-4-2-1-3-22(23)26/h1-7,12,18-19,21H,8-11,13-17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
38n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161449
PNG
(1-[4-(3,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1'...)
Show SMILES Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-22(19)18-26(31)30-14-10-23(11-15-30)29-12-8-20(9-13-29)16-21-6-7-24(27)25(28)17-21/h2-7,17,20,23H,8-16,18H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
40n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161436
PNG
(CHEMBL178438 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161436
PNG
(CHEMBL178438 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES COC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C29H33Cl2N3O2/c1-36-19-24-18-34(12-8-21(24)15-20-4-6-26(30)27(31)16-20)25-9-13-33(14-10-25)29(35)23-5-7-28-22(17-23)3-2-11-32-28/h2-7,11,16-17,21,24-25H,8-10,12-15,18-19H2,1H3/t21-,24+/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306012
PNG
(CHEMBL604683 | trans-4-chloro-2-(2-fluorophenylsul...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N[C@H]1CC[C@H](CNS(=O)(=O)C(F)(F)F)CC1 |r,wU:24.26,wD:21.22,(.36,-16.33,;-.98,-15.56,;-2.32,-16.33,;-3.65,-15.57,;-3.65,-14.02,;-2.32,-13.24,;-.98,-14.01,;.35,-13.23,;.74,-14.72,;1.83,-13.62,;.34,-11.7,;-.99,-10.94,;-1.01,-9.41,;-2.35,-8.64,;.33,-8.63,;1.67,-9.39,;1.67,-10.93,;3.01,-11.7,;2.6,-13.17,;4.33,-12.46,;3.76,-10.36,;5.3,-10.34,;6.08,-11.66,;7.61,-11.65,;8.37,-10.31,;9.9,-10.3,;10.66,-8.97,;12.19,-8.95,;12.17,-7.39,;13.52,-8.14,;12.99,-10.26,;14.53,-10.24,;12.24,-11.61,;13.77,-11.58,;7.59,-8.98,;6.04,-8.99,)|
Show InChI InChI=1S/C20H21ClF4N2O6S3/c21-14-7-10-18(19(11-14)34(28,29)17-4-2-1-3-16(17)22)35(30,31)27-15-8-5-13(6-9-15)12-26-36(32,33)20(23,24)25/h1-4,7,10-11,13,15,26-27H,5-6,8-9,12H2/t13-,15-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
43n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161409
PNG
(CHEMBL362017 | Cinnolin-4-yl-[4-(3,4-dichloro-benz...)
Show SMILES Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cnnc3ccccc23)cc1Cl
Show InChI InChI=1S/C26H28Cl2N4O/c27-23-6-5-19(16-24(23)28)15-18-7-11-31(12-8-18)20-9-13-32(14-10-20)26(33)22-17-29-30-25-4-2-1-3-21(22)25/h1-6,16-18,20H,7-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
46n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161425
PNG
(CHEMBL178422 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES FC[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2ncccc2c1
Show InChI InChI=1S/C28H30Cl2FN3O/c29-25-5-3-19(15-26(25)30)14-20-7-11-34(18-23(20)17-31)24-8-12-33(13-9-24)28(35)22-4-6-27-21(16-22)2-1-10-32-27/h1-6,10,15-16,20,23-24H,7-9,11-14,17-18H2/t20-,23-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
46n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161433
PNG
(CHEMBL441848 | [(3S,4S)-4-(3,4-Dichloro-benzyl)-3-...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1ccc2nccnc2c1
Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-6-19(26)14-18-2-4-22(28)23(29)15-18)21-7-12-32(13-8-21)27(34)20-3-5-24-25(16-20)31-10-9-30-24/h2-5,9-10,15-16,19,21,26H,6-8,11-14,17H2,1H3/t19-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
48n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161426
PNG
(1-[4-(2,4-Dichloro-benzyl)-[1,4'']bipiperidinyl-1'...)
Show SMILES Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Cl)cc2Cl)CC1
Show InChI InChI=1S/C26H32Cl2N2O/c1-19-4-2-3-5-21(19)17-26(31)30-14-10-24(11-15-30)29-12-8-20(9-13-29)16-22-6-7-23(27)18-25(22)28/h2-7,18,20,24H,8-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
56n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161431
PNG
(1-[4-(4-Bromo-benzyl)-[1,4'']bipiperidinyl-1''-yl]...)
Show SMILES Cc1ccccc1CC(=O)N1CCC(CC1)N1CCC(Cc2ccc(Br)cc2)CC1
Show InChI InChI=1S/C26H33BrN2O/c1-20-4-2-3-5-23(20)19-26(30)29-16-12-25(13-17-29)28-14-10-22(11-15-28)18-21-6-8-24(27)9-7-21/h2-9,22,25H,10-19H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
66n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161438
PNG
(CHEMBL178875 | [4-(3,4-Dichloro-benzyl)-[1,4'']bip...)
Show SMILES Clc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2cccc3cccnc23)cc1Cl
Show InChI InChI=1S/C27H29Cl2N3O/c28-24-7-6-20(18-25(24)29)17-19-8-13-31(14-9-19)22-10-15-32(16-11-22)27(33)23-5-1-3-21-4-2-12-30-26(21)23/h1-7,12,18-19,22H,8-11,13-17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
68n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50161406
PNG
(CHEMBL181929 | Cinnolin-4-yl-[(3S,4S)-4-(3,4-dichl...)
Show SMILES CO[C@@H]1CN(CC[C@@H]1Cc1ccc(Cl)c(Cl)c1)C1CCN(CC1)C(=O)c1cnnc2ccccc12
Show InChI InChI=1S/C27H30Cl2N4O2/c1-35-26-17-33(11-8-19(26)14-18-6-7-23(28)24(29)15-18)20-9-12-32(13-10-20)27(34)22-16-30-31-25-5-3-2-4-21(22)25/h2-7,15-16,19-20,26H,8-14,17H2,1H3/t19-,26-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
86n/an/an/an/an/an/an/an/a



Schering Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro binding affinity against C-C chemokine receptor type 3 expressing in rat Y3 cell line


Bioorg Med Chem Lett 15: 1375-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.016
BindingDB Entry DOI: 10.7270/Q2B857NS
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50306014
PNG
(CHEMBL594536 | N-(2-(1-(4-chloro-2-(2-fluorophenyl...)
Show SMILES Fc1ccccc1S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)N1CC(CCNS(=O)(=O)C(F)(F)F)C1
Show InChI InChI=1S/C18H17ClF4N2O6S3/c19-13-5-6-16(17(9-13)32(26,27)15-4-2-1-3-14(15)20)33(28,29)25-10-12(11-25)7-8-24-34(30,31)18(21,22)23/h1-6,9,12,24H,7-8,10-11H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
92n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 20: 608-11 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.084
BindingDB Entry DOI: 10.7270/Q2SB45V0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 818 total )  |  Next  |  Last  >>
Jump to: