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Compile Data Set for Download or QSAR

Found 1018 hits with Last Name = 'dzierba' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50074364
PNG
(CHEMBL350356 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...)
Show SMILES CCCCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C22H33BrN4/c1-7-10-13-26(8-2)21-14-17(6)24-22(25-21)27(9-3)20-12-11-18(16(4)5)15-19(20)23/h11-12,14-16H,7-10,13H2,1-6H3
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18n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1


J Med Chem 47: 5783-90 (2004)


Article DOI: 10.1021/jm049737f
BindingDB Entry DOI: 10.7270/Q2S75FT6
More data for this
Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase gamma


(Homo sapiens (Human))
BDBM50355636
PNG
(CHEMBL1403981)
Show SMILES OC(=O)c1sccc1SCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C12H8Cl2O2S2/c13-8-2-1-7(5-9(8)14)6-18-10-3-4-17-11(10)12(15)16/h1-5H,6H2,(H,15,16)
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2.50E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of RPTPgamma expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincub...


J Med Chem 54: 6548-62 (2011)


Article DOI: 10.1021/jm2003766
BindingDB Entry DOI: 10.7270/Q2862GTG
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311218
PNG
((S)-1-(2-cyclopropyl-4-(quinolin-4-yl)phenoxy)-2,4...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C1CC1)-c1ccnc2ccccc12 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311290
PNG
((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-4-...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cc(c(OC[C@@](C)(N)CC(C)C)cn1)C(F)(F)F |r|
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n/an/a 0.190n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311339
PNG
((S)-methyl (6-((2-amino-2,4-dimethylpentyl)oxy)-5-...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cnc(OC[C@@](C)(N)CC(C)C)c(c1)C(F)F |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311347
PNG
((S)-1-((3-(difluoromethyl)-5-(quinolin-4-yl)pyridi...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc2ccccc12 |r|
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n/an/a 0.230n/an/an/an/an/an/a



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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311289
PNG
((S)-2,4-dimethyl-1-((6-(quinolin-4-yl)-4-(trifluor...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)(F)F)-c1ccnc2ccccc12 |r|
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n/an/a 0.240n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311338
PNG
((S)-1-((3-(difluoromethyl)-5-(7-fluoroquinolin-4-y...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc2cc(F)ccc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50155982
PNG
(8-(Butyl-ethyl-amino)-4-(2-chloro-4-methoxy-phenyl...)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(OC)cc1Cl
Show InChI InChI=1S/C21H27ClN4O2/c1-5-7-10-25(6-2)18-11-14(3)23-21-20(18)24-19(27)13-26(21)17-9-8-15(28-4)12-16(17)22/h8-9,11-12H,5-7,10,13H2,1-4H3,(H,24,27)
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n/an/a 0.300n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1


J Med Chem 47: 5783-90 (2004)


Article DOI: 10.1021/jm049737f
BindingDB Entry DOI: 10.7270/Q2S75FT6
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311155
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-cyanop...)
Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C#N)-c1ccnc(NC(C)=O)c1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311265
PNG
((S)-1-((4-(difluoromethyl)-6-(quinolin-4-yl)pyridi...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1ccnc2ccccc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311340
PNG
((S)-1-((5-(7-chloroquinolin-4-yl)-3-(difluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc2cc(Cl)ccc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311229
PNG
((S)-1-(4-(1,6-naphthyridin-4-yl)-2-(trifluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2ccncc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311189
PNG
((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C1CC1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311176
PNG
((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C(F)(F)F |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311292
PNG
((S)-1-((4-(difluoromethyl)-5′-fluoro-2′...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1cc(C)ncc1F |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311170
PNG
((S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(t...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc(NC(C)=O)c1 |r|
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n/an/a 0.360n/an/an/an/an/an/a



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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311378
PNG
((S)-1-((4-chloro-6-(6-fluoroquinolin-4-yl)pyridin-...)
Show SMILES CC(C)C[C@@](C)(COc1cnc(cc1Cl)-c1ccnc2ccc(F)cc12)NC(=O)OC(C)(C)C |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311206
PNG
((S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(C)c1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311363
PNG
((S)-methyl (6-((2-amino-2,4-dimethylpentyl)oxy)-5-...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cnc(OC[C@@](C)(N)CC(C)C)c(c1)C(F)(F)F |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311382
PNG
((S)-1-((4-chloro-6-(6-chloroquinolin-4-yl)pyridin-...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1Cl)-c1ccnc2ccc(Cl)cc12 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM321130
PNG
((S)-8-((2-amino-2,4-dimethylpentyl)oxy)-7-chloro-6...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc-2c(COc3cnc(N)cc-23)c1Cl |r|
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n/an/a 0.410n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10174044 (2019)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q2222WVN
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311375
PNG
((S)-1-((6-(7-fluoroquinolin-4-yl)-4-methylpyridin-...)
Show SMILES CC(C)C[C@@](C)(COc1cnc(cc1C)-c1ccnc2cc(F)ccc12)NC(=O)OC(C)(C)C |r|
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n/an/a 0.410n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311159
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-methyl...)
Show SMILES CC(C)C[C@@H](COc1ccc(Br)cc1C)NC(=O)OC(C)(C)C |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311287
PNG
((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1cc(Cl)ncc1F |r|
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n/an/a 0.450n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311232
PNG
((S)-1-(4-(7-chloroquinolin-4-yl)-2-(trifluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(Cl)ccc12 |r|
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n/an/a 0.460n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311374
PNG
((S)-1-((6-(7-chloroquinolin-4-yl)-4-methylpyridin-...)
Show SMILES CC(C)C[C@@](C)(COc1cnc(cc1C)-c1ccnc2cc(Cl)ccc12)NC(=O)OC(C)(C)C |r|
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n/an/a 0.470n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311158
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-(trifl...)
Show SMILES CC(C)C[C@H](N)COc1ccc(cc1OC(F)(F)F)-c1ccnc(NC(C)=O)c1 |r|
PDB

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n/an/a 0.470n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311332
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...)
Show SMILES CC(C)C[C@@](C)(COc1ncc(cc1Cl)-c1ccnc2cc(F)cc(F)c12)NC(=O)OC(C)(C)C |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311222
PNG
((S)-1-((3-chloro-5-(quinolin-4-yl)pyridin-2-yl)oxy...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1Cl)-c1ccnc2ccccc12 |r|
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US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50155974
PNG
(8-(Butyl-ethyl-amino)-4-(2,4-dichloro-phenyl)-6-me...)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H24Cl2N4O/c1-4-6-9-25(5-2)17-10-13(3)23-20-19(17)24-18(27)12-26(20)16-8-7-14(21)11-15(16)22/h7-8,10-11H,4-6,9,12H2,1-3H3,(H,24,27)
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n/an/a 0.490n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1


J Med Chem 47: 5783-90 (2004)


Article DOI: 10.1021/jm049737f
BindingDB Entry DOI: 10.7270/Q2S75FT6
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50155964
PNG
(8-(Butyl-ethyl-amino)-4-(2-chloro-5-fluoro-4-metho...)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1cc(F)c(OC)cc1Cl
Show InChI InChI=1S/C21H26ClFN4O2/c1-5-7-8-26(6-2)17-9-13(3)24-21-20(17)25-19(28)12-27(21)16-11-15(23)18(29-4)10-14(16)22/h9-11H,5-8,12H2,1-4H3,(H,25,28)
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Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1


J Med Chem 47: 5783-90 (2004)


Article DOI: 10.1021/jm049737f
BindingDB Entry DOI: 10.7270/Q2S75FT6
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311157
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-(trifl...)
Show SMILES CC(C)C[C@H](N)COc1ccc(cc1C(F)(F)F)-c1ccnc(NC(C)=O)c1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311217
PNG
((S)-1-(4-(6-fluoroquinolin-4-yl)-2-(trifluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2ccc(F)cc12 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311193
PNG
((S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyr...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)F)-c1ccnc(c1)C(F)F |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311266
PNG
((S)-1-((4-(difluoromethyl)-2′-methyl-[2,4...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1ccnc(C)c1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311264
PNG
((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-4-...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1cc(C(F)F)c(OC[C@@](C)(N)CC(C)C)cn1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311216
PNG
((S)-1-(4-(5,7-difluoroquinolin-4-yl)-2-(trifluorom...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(F)cc(F)c12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311160
PNG
((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-chloro...)
Show SMILES CC(C)C[C@@H](COc1ccc(Br)cc1Cl)NC(=O)OC(C)(C)C |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311215
PNG
((S)-1-(4-(7-fluoroquinolin-4-yl)-2-(trifluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(F)ccc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311291
PNG
((S)-1-((2′-chloro-4-(difluoromethyl)-[2,4...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1ccnc(Cl)c1 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311360
PNG
((S)-1-(4-(6-chloroquinolin-4-yl)-2-(trifluoromethy...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccnc2ccc(Cl)cc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311362
PNG
((S)-2,4-dimethyl-1-((5-(quinolin-4-yl)-3-(trifluor...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)(F)F)-c1ccnc2ccccc12 |r|
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US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM321107
PNG
((S)-ethyl (8-((2-amino-2,4-dimethylpentyl)oxy)-6H-...)
Show SMILES CCOC(=O)Nc1cc-2c(OCc3cc(OC[C@@](C)(N)CC(C)C)ccc-23)cn1 |r|
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US Patent




US Patent US10174044 (2019)


Article DOI: 10.1016/j.bmcl.2009.03.077
BindingDB Entry DOI: 10.7270/Q2222WVN
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311250
PNG
((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Show SMILES COC(=O)Nc1cc(c(F)cn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C#N |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311180
PNG
((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C(F)F |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311344
PNG
((S)-1-((3-(difluoromethyl)-5-(5,7-difluoroquinolin...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc2cc(F)cc(F)c12 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311199
PNG
((S)-2,4-dimethyl-1-(4-(pyridin-4-yl)-2-(trifluorom...)
Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1ccncc1 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311210
PNG
((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(Cl)n1 |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311178
PNG
((S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)...)
Show SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(c1)C#N |r|
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Bristol-Myers Squibb Company

US Patent




US Patent US10155760 (2018)


Article DOI: 10.1021/jm070311l
BindingDB Entry DOI: 10.7270/Q2F191S4
More data for this
Ligand-Target Pair
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