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Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'eleutheriades' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382166
PNG
(CHEMBL2023825)
Show SMILES C1CCC(CC1)N1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:18:25:28.27.32:30,THB:26:27:30:34.25.33,26:25:28.27.32:30,33:25:28:32.31.30,33:31:28:34.26.25,18:25:28:32.31.30|
Show InChI InChI=1S/C33H44N2/c1-3-7-28(8-4-1)32(33-22-25-19-26(23-33)21-27(20-25)24-33)29-11-13-31(14-12-29)35-17-15-34(16-18-35)30-9-5-2-6-10-30/h1,3-4,7-8,11-14,25-27,30,32H,2,5-6,9-10,15-24H2
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n/an/a 0.270n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401861
PNG
(CHEMBL2204672)
Show SMILES CN1CCN(CCc2ccc(cc2)C(c2ccccc2)C23CC4CC(CC(C4)C2)C3)CC1 |TLB:13:20:23.22.27:25,THB:21:22:25:29.20.28,21:20:23.22.27:25,28:20:23:27.26.25,28:26:23:29.21.20,13:20:23:27.26.25|
Show InChI InChI=1S/C30H40N2/c1-31-13-15-32(16-14-31)12-11-23-7-9-28(10-8-23)29(27-5-3-2-4-6-27)30-20-24-17-25(21-30)19-26(18-24)22-30/h2-10,24-26,29H,11-22H2,1H3
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n/an/a 2.90n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382169
PNG
(CHEMBL2023824)
Show SMILES CCN1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:14:21:24.23.28:26,THB:22:23:26:30.21.29,22:21:24.23.28:26,29:21:24:28.27.26,29:27:24:30.22.21,14:21:24:28.27.26|
Show InChI InChI=1S/C29H38N2/c1-2-30-12-14-31(15-13-30)27-10-8-26(9-11-27)28(25-6-4-3-5-7-25)29-19-22-16-23(20-29)18-24(17-22)21-29/h3-11,22-24,28H,2,12-21H2,1H3
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n/an/a 2.90n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382165
PNG
(CHEMBL2023823)
Show SMILES CN1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:13:20:23.22.27:25,THB:21:22:25:29.20.28,21:20:23.22.27:25,28:20:23:27.26.25,28:26:23:29.21.20,13:20:23:27.26.25|
Show InChI InChI=1S/C28H36N2/c1-29-11-13-30(14-12-29)26-9-7-25(8-10-26)27(24-5-3-2-4-6-24)28-18-21-15-22(19-28)17-23(16-21)20-28/h2-10,21-23,27H,11-20H2,1H3
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n/an/a 3.20n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401862
PNG
(CHEMBL2204668)
Show SMILES CN1CCN(Cc2ccc(cc2)C(c2ccccc2)C23CC4CC(CC(C4)C2)C3)CC1 |TLB:12:19:22.21.26:24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19,12:19:22:26.25.24|
Show InChI InChI=1S/C29H38N2/c1-30-11-13-31(14-12-30)21-22-7-9-27(10-8-22)28(26-5-3-2-4-6-26)29-18-23-15-24(19-29)17-25(16-23)20-29/h2-10,23-25,28H,11-21H2,1H3
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n/an/a 5.20n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401857
PNG
(CHEMBL2204679)
Show SMILES C(CN1CCCCC1)Cc1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:15:22:25.24.29:27,THB:15:22:25:29.28.27,23:24:27:31.22.30,23:22:25.24.29:27,30:22:25:29.28.27,30:28:25:31.23.22|
Show InChI InChI=1S/C31H41N/c1-3-9-28(10-4-1)30(31-21-25-18-26(22-31)20-27(19-25)23-31)29-13-11-24(12-14-29)8-7-17-32-15-5-2-6-16-32/h1,3-4,9-14,25-27,30H,2,5-8,15-23H2
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n/an/a 12.3n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382168
PNG
(CHEMBL2023827)
Show SMILES C1CN(CCN1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:12:19:22.21.26:24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19,12:19:22:26.25.24|
Show InChI InChI=1S/C27H34N2/c1-2-4-23(5-3-1)26(27-17-20-14-21(18-27)16-22(15-20)19-27)24-6-8-25(9-7-24)29-12-10-28-11-13-29/h1-9,20-22,26,28H,10-19H2
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n/an/a 12.4n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401859
PNG
(CHEMBL2204677)
Show SMILES C(CN1CCN(Cc2ccccc2)CC1)Cc1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:22:29:32.31.36:34,THB:22:29:32:36.35.34,37:29:32:36.35.34,37:35:32:38.30.29,30:31:34:38.29.37,30:29:32.31.36:34|
Show InChI InChI=1S/C37H46N2/c1-3-8-30(9-4-1)28-39-20-18-38(19-21-39)17-7-10-29-13-15-35(16-14-29)36(34-11-5-2-6-12-34)37-25-31-22-32(26-37)24-33(23-31)27-37/h1-6,8-9,11-16,31-33,36H,7,10,17-28H2
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n/an/a 36.1n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401858
PNG
(CHEMBL2204678)
Show SMILES C(CN1CCNCC1)Cc1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:15:22:25.24.29:27,THB:15:22:25:29.28.27,23:24:27:31.22.30,23:22:25.24.29:27,30:22:25:29.28.27,30:28:25:31.23.22|
Show InChI InChI=1S/C30H40N2/c1-2-6-27(7-3-1)29(30-20-24-17-25(21-30)19-26(18-24)22-30)28-10-8-23(9-11-28)5-4-14-32-15-12-31-13-16-32/h1-3,6-11,24-26,29,31H,4-5,12-22H2
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n/an/a 42n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50401860
PNG
(CHEMBL2204675)
Show SMILES CN1CCN(CCCc2ccc(cc2)C(c2ccccc2)C23CC4CC(CC(C4)C2)C3)CC1 |TLB:14:21:24.23.28:26,THB:14:21:24:28.27.26,29:21:24:28.27.26,29:27:24:30.22.21,22:23:26:30.21.29,22:21:24.23.28:26|
Show InChI InChI=1S/C31H42N2/c1-32-14-16-33(17-15-32)13-5-6-24-9-11-29(12-10-24)30(28-7-3-2-4-8-28)31-21-25-18-26(22-31)20-27(19-25)23-31/h2-4,7-12,25-27,30H,5-6,13-23H2,1H3
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n/an/a 48.1n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in human Jurkat cell membrane


J Med Chem 55: 10241-61 (2012)


Article DOI: 10.1021/jm3013008
BindingDB Entry DOI: 10.7270/Q2736S3Z
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382167
PNG
(CHEMBL2023826)
Show SMILES C(N1CCN(CC1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2)c1ccccc1 |TLB:13:20:23.22.27:25,THB:21:22:25:29.20.28,21:20:23.22.27:25,28:20:23:27.26.25,28:26:23:29.21.20,13:20:23:27.26.25|
Show InChI InChI=1S/C34H40N2/c1-3-7-26(8-4-1)25-35-15-17-36(18-16-35)32-13-11-31(12-14-32)33(30-9-5-2-6-10-30)34-22-27-19-28(23-34)21-29(20-27)24-34/h1-14,27-29,33H,15-25H2
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n/an/a 63.3n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50382164
PNG
(CHEMBL2023828)
Show SMILES C1CN(CCO1)c1ccc(cc1)C(c1ccccc1)C12CC3CC(CC(C3)C1)C2 |TLB:12:19:22.21.26:24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19,12:19:22:26.25.24|
Show InChI InChI=1S/C27H33NO/c1-2-4-23(5-3-1)26(27-17-20-14-21(18-27)16-22(15-20)19-27)24-6-8-25(9-7-24)28-10-12-29-13-11-28/h1-9,20-22,26H,10-19H2
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n/an/a>100n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy


Bioorg Med Chem 20: 3323-31 (2012)


Article DOI: 10.1016/j.bmc.2012.03.038
BindingDB Entry DOI: 10.7270/Q20V8DT0
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423058
PNG
(CHEMBL244471)
Show SMILES O=C(NCCc1cn2CCCc3cccc1c23)C1CC1
Show InChI InChI=1S/C17H20N2O/c20-17(13-6-7-13)18-9-8-14-11-19-10-2-4-12-3-1-5-15(14)16(12)19/h1,3,5,11,13H,2,4,6-10H2,(H,18,20)
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n/an/a 282n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423056
PNG
(CHEMBL243002)
Show SMILES CC(=O)NCC1(CCCCC1)c1cn2CCCc3cccc1c23
Show InChI InChI=1S/C20H26N2O/c1-15(23)21-14-20(10-3-2-4-11-20)18-13-22-12-6-8-16-7-5-9-17(18)19(16)22/h5,7,9,13H,2-4,6,8,10-12,14H2,1H3,(H,21,23)
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n/an/a 1.18E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423059
PNG
(CHEMBL244472)
Show SMILES CCCC(=O)NCCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C18H24N2O/c1-2-6-17(21)19-11-4-8-15-13-20-12-5-9-14-7-3-10-16(15)18(14)20/h3,7,10,13H,2,4-6,8-9,11-12H2,1H3,(H,19,21)
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n/an/a 1.41E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423057
PNG
(CHEMBL242573)
Show SMILES O=C(NCCCc1cn2CCCc3cccc1c23)C1CC1
Show InChI InChI=1S/C18H22N2O/c21-18(14-8-9-14)19-10-2-5-15-12-20-11-3-6-13-4-1-7-16(15)17(13)20/h1,4,7,12,14H,2-3,5-6,8-11H2,(H,19,21)
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n/an/a 1.51E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423062
PNG
(CHEMBL242786)
Show SMILES O=C(NCCCc1cn2CCCc3cccc1c23)C1CCC1
Show InChI InChI=1S/C19H24N2O/c22-19(15-6-1-7-15)20-11-3-8-16-13-21-12-4-9-14-5-2-10-17(16)18(14)21/h2,5,10,13,15H,1,3-4,6-9,11-12H2,(H,20,22)
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n/an/a 1.59E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423063
PNG
(CHEMBL396501)
Show SMILES CCCC(=O)NCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C17H22N2O/c1-2-5-16(20)18-10-9-14-12-19-11-4-7-13-6-3-8-15(14)17(13)19/h3,6,8,12H,2,4-5,7,9-11H2,1H3,(H,18,20)
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n/an/a 1.70E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423061
PNG
(CHEMBL243003)
Show SMILES CCCC(=O)NCC1(CCCCC1)c1cn2CCCc3cccc1c23
Show InChI InChI=1S/C22H30N2O/c1-2-8-20(25)23-16-22(12-4-3-5-13-22)19-15-24-14-7-10-17-9-6-11-18(19)21(17)24/h6,9,11,15H,2-5,7-8,10,12-14,16H2,1H3,(H,23,25)
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n/an/a 2.04E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423055
PNG
(CHEMBL244957)
Show SMILES CCC(=O)NCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C16H20N2O/c1-2-15(19)17-9-8-13-11-18-10-4-6-12-5-3-7-14(13)16(12)18/h3,5,7,11H,2,4,6,8-10H2,1H3,(H,17,19)
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n/an/a 2.19E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM85065
PNG
(CAS_117946-91-5 | Luzindole | NSC_122162)
Show SMILES CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12
Show InChI InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
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n/an/a 2.46E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423064
PNG
(CHEMBL244263)
Show SMILES CCC(=O)NCCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C17H22N2O/c1-2-16(20)18-10-4-7-14-12-19-11-5-8-13-6-3-9-15(14)17(13)19/h3,6,9,12H,2,4-5,7-8,10-11H2,1H3,(H,18,20)
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n/an/a 4.68E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423060
PNG
(CHEMBL241928)
Show SMILES CC(=O)NCCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C16H20N2O/c1-12(19)17-9-3-6-14-11-18-10-4-7-13-5-2-8-15(14)16(13)18/h2,5,8,11H,3-4,6-7,9-10H2,1H3,(H,17,19)
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n/an/a 5.13E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50423065
PNG
(CHEMBL242806)
Show SMILES CC(=O)NCCc1cn2CCCc3cccc1c23
Show InChI InChI=1S/C15H18N2O/c1-11(18)16-8-7-13-10-17-9-3-5-12-4-2-6-14(13)15(12)17/h2,4,6,10H,3,5,7-9H2,1H3,(H,16,18)
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n/an/a 6.17E+3n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair
Melatonin 1C


(Xenopus)
BDBM50411361
PNG
(CHEMBL396991)
Show SMILES CC(=O)NCC(C)(C)c1cn2CCCc3cccc1c23
Show InChI InChI=1S/C17H22N2O/c1-12(20)18-11-17(2,3)15-10-19-9-5-7-13-6-4-8-14(15)16(13)19/h4,6,8,10H,5,7,9,11H2,1-3H3,(H,18,20)
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n/an/a 1.00E+5n/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Antagonist activity in Xenopus laevis melanophores assessed as melatoninergic activity after 60 mins


Eur J Med Chem 42: 1004-13 (2007)


Article DOI: 10.1016/j.ejmech.2007.01.005
BindingDB Entry DOI: 10.7270/Q2B859BK
More data for this
Ligand-Target Pair