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Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'forsyth' and Initial = 'ne'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Mus musculus)
BDBM50142891
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1C1=NCCN1 |t:19|
Show InChI InChI=1S/C18H19BrN2O/c1-22-17-9-8-15(19)12-14(17)7-6-13-4-2-3-5-16(13)18-20-10-11-21-18/h2-5,8-9,12H,6-7,10-11H2,1H3,(H,20,21)
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39n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142894
PNG
(2-[2-(5-Bromo-2-methoxy-benzylsulfanyl)-phenyl]-1,...)
Show SMILES COc1ccc(Br)cc1CSc1ccccc1C1=NCCCN1 |t:19|
Show InChI InChI=1S/C18H19BrN2OS/c1-22-16-8-7-14(19)11-13(16)12-23-17-6-3-2-5-15(17)18-20-9-4-10-21-18/h2-3,5-8,11H,4,9-10,12H2,1H3,(H,20,21)
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67n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148972
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1-c1nc(C)c(C)n1C
Show InChI InChI=1S/C21H23BrN2O/c1-14-15(2)24(3)21(23-14)19-8-6-5-7-16(19)9-10-17-13-18(22)11-12-20(17)25-4/h5-8,11-13H,9-10H2,1-4H3
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140n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142895
PNG
(2-(2-(5-bromo-2-methoxyphenethyl)-3-fluorophenyl)-...)
Show SMILES COc1ccc(Br)cc1CCc1c(F)cccc1C1=NCCN1 |t:20|
Show InChI InChI=1S/C18H18BrFN2O/c1-23-17-8-6-13(19)11-12(17)5-7-14-15(3-2-4-16(14)20)18-21-9-10-22-18/h2-4,6,8,11H,5,7,9-10H2,1H3,(H,21,22)
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160n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148977
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1-c1ncc(C)n1C
Show InChI InChI=1S/C20H21BrN2O/c1-14-13-22-20(23(14)2)18-7-5-4-6-15(18)8-9-16-12-17(21)10-11-19(16)24-3/h4-7,10-13H,8-9H2,1-3H3
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180n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148974
PNG
(3-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1ncc2CCCn12
Show InChI InChI=1S/C21H20BrClN2O/c1-26-20-10-8-15(22)12-14(20)7-9-17-18(5-2-6-19(17)23)21-24-13-16-4-3-11-25(16)21/h2,5-6,8,10,12-13H,3-4,7,9,11H2,1H3
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180n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142897
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1C1=NCCCN1 |t:19|
Show InChI InChI=1S/C19H21BrN2O/c1-23-18-10-9-16(20)13-15(18)8-7-14-5-2-3-6-17(14)19-21-11-4-12-22-19/h2-3,5-6,9-10,13H,4,7-8,11-12H2,1H3,(H,21,22)
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220n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148976
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1-c1nc(C)cn1C
Show InChI InChI=1S/C20H21BrN2O/c1-14-13-23(2)20(22-14)18-7-5-4-6-15(18)8-9-16-12-17(21)10-11-19(16)24-3/h4-7,10-13H,8-9H2,1-3H3
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270n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148967
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1nccn1C
Show InChI InChI=1S/C19H18BrClN2O/c1-23-11-10-22-19(23)16-4-3-5-17(21)15(16)8-6-13-12-14(20)7-9-18(13)24-2/h3-5,7,9-12H,6,8H2,1-2H3
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300n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148969
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES CCn1ccnc1-c1cccc(Cl)c1CCc1cc(Br)ccc1OC
Show InChI InChI=1S/C20H20BrClN2O/c1-3-24-12-11-23-20(24)17-5-4-6-18(22)16(17)9-7-14-13-15(21)8-10-19(14)25-2/h4-6,8,10-13H,3,7,9H2,1-2H3
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310n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148973
PNG
(3-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Show SMILES COc1ccc(Br)cc1CCc1c(F)cccc1-c1ncc2CCCn12
Show InChI InChI=1S/C21H20BrFN2O/c1-26-20-10-8-15(22)12-14(20)7-9-17-18(5-2-6-19(17)23)21-24-13-16-4-3-11-25(16)21/h2,5-6,8,10,12-13H,3-4,7,9,11H2,1H3
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320n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148978
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES CCc1cnc(-c2ccccc2CCc2cc(Br)ccc2OC)n1C
Show InChI InChI=1S/C21H23BrN2O/c1-4-18-14-23-21(24(18)2)19-8-6-5-7-15(19)9-10-16-13-17(22)11-12-20(16)25-3/h5-8,11-14H,4,9-10H2,1-3H3
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320n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148983
PNG
(3-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1ncc2CCCCn12
Show InChI InChI=1S/C22H22BrClN2O/c1-27-21-11-9-16(23)13-15(21)8-10-18-19(6-4-7-20(18)24)22-25-14-17-5-2-3-12-26(17)22/h4,6-7,9,11,13-14H,2-3,5,8,10,12H2,1H3
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340n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148981
PNG
(3-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-fluoro...)
Show SMILES COc1ccc(Br)cc1CCc1c(F)cccc1-c1ncc2CCCCn12
Show InChI InChI=1S/C22H22BrFN2O/c1-27-21-11-9-16(23)13-15(21)8-10-18-19(6-4-7-20(18)24)22-25-14-17-5-2-3-12-26(17)22/h4,6-7,9,11,13-14H,2-3,5,8,10,12H2,1H3
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620n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148971
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1nccn1C(C)C
Show InChI InChI=1S/C21H22BrClN2O/c1-14(2)25-12-11-24-21(25)18-5-4-6-19(23)17(18)9-7-15-13-16(22)8-10-20(15)26-3/h4-6,8,10-14H,7,9H2,1-3H3
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670n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148984
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES CCc1cn(C)c(n1)-c1ccccc1CCc1cc(Br)ccc1OC
Show InChI InChI=1S/C21H23BrN2O/c1-4-18-14-24(2)21(23-18)19-8-6-5-7-15(19)9-10-16-13-17(22)11-12-20(16)25-3/h5-8,11-14H,4,9-10H2,1-3H3
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690n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148980
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES CCCn1ccnc1-c1cccc(Cl)c1CCc1cc(Br)ccc1OC
Show InChI InChI=1S/C21H22BrClN2O/c1-3-12-25-13-11-24-21(25)18-5-4-6-19(23)17(18)9-7-15-14-16(22)8-10-20(15)26-2/h4-6,8,10-11,13-14H,3,7,9,12H2,1-2H3
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1.30E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148970
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1ncc[nH]1
Show InChI InChI=1S/C18H16BrClN2O/c1-23-17-8-6-13(19)11-12(17)5-7-14-15(3-2-4-16(14)20)18-21-9-10-22-18/h2-4,6,8-11H,5,7H2,1H3,(H,21,22)
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1.50E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148975
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-phenyl}-...)
Show SMILES COc1ccc(Br)cc1CCc1ccccc1-c1nc(cn1C)C(C)C
Show InChI InChI=1S/C22H25BrN2O/c1-15(2)20-14-25(3)22(24-20)19-8-6-5-7-16(19)9-10-17-13-18(23)11-12-21(17)26-4/h5-8,11-15H,9-10H2,1-4H3
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1.60E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148968
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1nccn1CC1CC1
Show InChI InChI=1S/C22H22BrClN2O/c1-27-21-10-8-17(23)13-16(21)7-9-18-19(3-2-4-20(18)24)22-25-11-12-26(22)14-15-5-6-15/h2-4,8,10-13,15H,5-7,9,14H2,1H3
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2.00E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142893
PNG
(2-[2-(2,5-Dichloro-thiophen-3-ylmethylsulfanyl)-ph...)
Show SMILES Clc1cc(CSc2ccccc2C2=NCCCN2)c(Cl)s1 |t:13|
Show InChI InChI=1S/C15H14Cl2N2S2/c16-13-8-10(14(17)21-13)9-20-12-5-2-1-4-11(12)15-18-6-3-7-19-15/h1-2,4-5,8H,3,6-7,9H2,(H,18,19)
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2.20E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148979
PNG
(2-{2-[2-(5-Bromo-2-methoxy-phenyl)-ethyl]-3-chloro...)
Show SMILES CCC(C)n1ccnc1-c1cccc(Cl)c1CCc1cc(Br)ccc1OC
Show InChI InChI=1S/C22H24BrClN2O/c1-4-15(2)26-13-12-25-22(26)19-6-5-7-20(24)18(19)10-8-16-14-17(23)9-11-21(16)27-3/h5-7,9,11-15H,4,8,10H2,1-3H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142896
PNG
(2-[2-(2-Chloro-6-fluoro-benzylsulfanyl)-phenyl]-1,...)
Show SMILES Fc1cccc(Cl)c1CSc1ccccc1C1=NCCCN1 |t:18|
Show InChI InChI=1S/C17H16ClFN2S/c18-14-6-3-7-15(19)13(14)11-22-16-8-2-1-5-12(16)17-20-9-4-10-21-17/h1-3,5-8H,4,9-11H2,(H,20,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
2.70E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50148982
PNG
(4-Bromo-2-{2-[2-chloro-6-(1-methyl-1H-imidazol-2-y...)
Show SMILES Cn1ccnc1-c1cccc(Cl)c1CCc1cc(Br)ccc1O
Show InChI InChI=1S/C18H16BrClN2O/c1-22-10-9-21-18(22)15-3-2-4-16(20)14(15)7-5-12-11-13(19)6-8-17(12)23/h2-4,6,8-11,23H,5,7H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
9.30E+3n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro binding affinity towards melanocortin 4 receptor.


Bioorg Med Chem Lett 14: 3721-5 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.003
BindingDB Entry DOI: 10.7270/Q2JS9PWV
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Mus musculus)
BDBM50142892
PNG
(2-[2-(2,6-Difluoro-benzylsulfanyl)-phenyl]-1,4,5,6...)
Show SMILES Fc1cccc(F)c1CSc1ccccc1C1=NCCCN1 |t:18|
Show InChI InChI=1S/C17H16F2N2S/c18-14-6-3-7-15(19)13(14)11-22-16-8-2-1-5-12(16)17-20-9-4-10-21-17/h1-3,5-8H,4,9-11H2,(H,20,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
1.58E+4n/an/an/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonistic activity of the compound was determined against mice melanocortin 4 receptor using [125I]-[NDP]-R-MSH as radioligand in a membranefiltra...


J Med Chem 47: 1602-4 (2004)


Article DOI: 10.1021/jm034244g
BindingDB Entry DOI: 10.7270/Q2JQ10GG
More data for this
Ligand-Target Pair