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Compile Data Set for Download or QSAR

Found 51 hits with Last Name = 'gay' and Initial = 'ea'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023665
PNG
(CHEMBL3341759)
Show SMILES CN(C)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H19ClN4O/c1-25(2)19-8-4-7-18(24-19)14-5-3-6-17(13-14)23-20(26)22-16-11-9-15(21)10-12-16/h3-13H,1-2H3,(H2,22,23,26)
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n/an/a 27n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023667
PNG
(CHEMBL3341878)
Show SMILES Fc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21FN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/a 32n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023629
PNG
(CHEMBL3341861)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/a 33n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023633
PNG
(CHEMBL3341880)
Show SMILES O=C(Nc1ccc(cc1)C#N)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C23H21N5O/c24-16-17-9-11-19(12-10-17)25-23(29)26-20-6-3-5-18(15-20)21-7-4-8-22(27-21)28-13-1-2-14-28/h3-12,15H,1-2,13-14H2,(H2,25,26,29)
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n/an/a 33n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023704
PNG
(CHEMBL3341873)
Show SMILES CCN(C)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C21H21ClN4O/c1-3-26(2)20-9-5-8-19(25-20)15-6-4-7-18(14-15)24-21(27)23-17-12-10-16(22)11-13-17/h4-14H,3H2,1-2H3,(H2,23,24,27)
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n/an/a 54n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023666
PNG
(CHEMBL3341869)
Show SMILES CCCCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C22H23ClN4O/c1-2-3-14-24-21-9-5-8-20(27-21)16-6-4-7-19(15-16)26-22(28)25-18-12-10-17(23)11-13-18/h4-13,15H,2-3,14H2,1H3,(H,24,27)(H2,25,26,28)
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n/an/a 93n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023630
PNG
(CHEMBL3341862)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCCC2)cc1
Show InChI InChI=1S/C23H23ClN4O/c24-18-10-12-19(13-11-18)25-23(29)26-20-7-4-6-17(16-20)21-8-5-9-22(27-21)28-14-2-1-3-15-28/h4-13,16H,1-3,14-15H2,(H2,25,26,29)
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n/an/a 95n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023724
PNG
(CHEMBL3341879)
Show SMILES Brc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21BrN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/a 98n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50098802
PNG
(CHEMBL3341881)
Show SMILES [O-][N+](=O)c1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21N5O3/c28-22(23-17-9-11-19(12-10-17)27(29)30)24-18-6-3-5-16(15-18)20-7-4-8-21(25-20)26-13-1-2-14-26/h3-12,15H,1-2,13-14H2,(H2,23,24,28)
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n/an/a 100n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023719
PNG
(CHEMBL3341875)
Show SMILES CCCCN(C)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C23H25ClN4O/c1-3-4-15-28(2)22-10-6-9-21(27-22)17-7-5-8-20(16-17)26-23(29)25-19-13-11-18(24)12-14-19/h5-14,16H,3-4,15H2,1-2H3,(H2,25,26,29)
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n/an/a 104n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023687
PNG
(CHEMBL3341863)
Show SMILES CCN(CC)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C22H23ClN4O/c1-3-27(4-2)21-10-6-9-20(26-21)16-7-5-8-19(15-16)25-22(28)24-18-13-11-17(23)12-14-18/h5-15H,3-4H2,1-2H3,(H2,24,25,28)
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n/an/a 125n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023669
PNG
(CHEMBL3341894)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cn1
Show InChI InChI=1S/C21H20ClN5O/c22-19-10-9-17(14-23-19)25-21(28)24-16-6-3-5-15(13-16)18-7-4-8-20(26-18)27-11-1-2-12-27/h3-10,13-14H,1-2,11-12H2,(H2,24,25,28)
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n/an/a 135n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023715
PNG
(CHEMBL3341874)
Show SMILES CCCN(C)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C22H23ClN4O/c1-3-14-27(2)21-9-5-8-20(26-21)16-6-4-7-19(15-16)25-22(28)24-18-12-10-17(23)11-13-18/h4-13,15H,3,14H2,1-2H3,(H2,24,25,28)
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n/an/a 156n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023663
PNG
(CHEMBL3341892)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1Cl
Show InChI InChI=1S/C22H20Cl2N4O/c23-18-10-9-17(14-19(18)24)26-22(29)25-16-6-3-5-15(13-16)20-7-4-8-21(27-20)28-11-1-2-12-28/h3-10,13-14H,1-2,11-12H2,(H2,25,26,29)
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n/an/a 161n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023723
PNG
(CHEMBL3341877)
Show SMILES O=C(Nc1ccccc1)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C22H22N4O/c27-22(23-18-9-2-1-3-10-18)24-19-11-6-8-17(16-19)20-12-7-13-21(25-20)26-14-4-5-15-26/h1-3,6-13,16H,4-5,14-15H2,(H2,23,24,27)
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n/an/a 166n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023691
PNG
(CHEMBL3341867)
Show SMILES CCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H19ClN4O/c1-2-22-19-8-4-7-18(25-19)14-5-3-6-17(13-14)24-20(26)23-16-11-9-15(21)10-12-16/h3-13H,2H2,1H3,(H,22,25)(H2,23,24,26)
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n/an/a 181n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023671
PNG
(CHEMBL3341883)
Show SMILES COc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C23H24N4O2/c1-29-20-12-10-18(11-13-20)24-23(28)25-19-7-4-6-17(16-19)21-8-5-9-22(26-21)27-14-2-3-15-27/h4-13,16H,2-3,14-15H2,1H3,(H2,24,25,28)
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n/an/a 189n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023670
PNG
(CHEMBL3341882)
Show SMILES Cc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C23H24N4O/c1-17-10-12-19(13-11-17)24-23(28)25-20-7-4-6-18(16-20)21-8-5-9-22(26-21)27-14-2-3-15-27/h4-13,16H,2-3,14-15H2,1H3,(H2,24,25,28)
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n/an/a 203n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023679
PNG
(CHEMBL3341891)
Show SMILES Clc1cccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1
Show InChI InChI=1S/C22H21ClN4O/c23-17-7-4-9-19(15-17)25-22(28)24-18-8-3-6-16(14-18)20-10-5-11-21(26-20)27-12-1-2-13-27/h3-11,14-15H,1-2,12-13H2,(H2,24,25,28)
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n/an/a 228n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023632
PNG
(CHEMBL3341876)
Show SMILES CC(=O)Nc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H17ClN4O2/c1-13(26)22-19-7-3-6-18(25-19)14-4-2-5-17(12-14)24-20(27)23-16-10-8-15(21)9-11-16/h2-12H,1H3,(H,22,25,26)(H2,23,24,27)
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n/an/a 251n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023692
PNG
(CHEMBL3341868)
Show SMILES CCCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C21H21ClN4O/c1-2-13-23-20-8-4-7-19(26-20)15-5-3-6-18(14-15)25-21(27)24-17-11-9-16(22)10-12-17/h3-12,14H,2,13H2,1H3,(H,23,26)(H2,24,25,27)
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n/an/a 311n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023673
PNG
(CHEMBL3341885)
Show SMILES O=C(Nc1ccc2OCOc2c1)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C23H22N4O3/c28-23(25-18-9-10-20-21(14-18)30-15-29-20)24-17-6-3-5-16(13-17)19-7-4-8-22(26-19)27-11-1-2-12-27/h3-10,13-14H,1-2,11-12,15H2,(H2,24,25,28)
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n/an/a 312n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023690
PNG
(CHEMBL3341866)
Show SMILES CNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H17ClN4O/c1-21-18-7-3-6-17(24-18)13-4-2-5-16(12-13)23-19(25)22-15-10-8-14(20)9-11-15/h2-12H,1H3,(H,21,24)(H2,22,23,25)
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n/an/a 317n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023688
PNG
(CHEMBL3341864)
Show SMILES CCCN(CCC)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C24H27ClN4O/c1-3-15-29(16-4-2)23-10-6-9-22(28-23)18-7-5-8-21(17-18)27-24(30)26-20-13-11-19(25)12-14-20/h5-14,17H,3-4,15-16H2,1-2H3,(H2,26,27,30)
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n/an/a 372n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023631
PNG
(CHEMBL3341872)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(NC3CCCC3)n2)cc1
Show InChI InChI=1S/C23H23ClN4O/c24-17-11-13-19(14-12-17)26-23(29)27-20-8-3-5-16(15-20)21-9-4-10-22(28-21)25-18-6-1-2-7-18/h3-5,8-15,18H,1-2,6-7H2,(H,25,28)(H2,26,27,29)
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n/an/a 501n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023689
PNG
(CHEMBL3341865)
Show SMILES CCCCN(CCCC)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C26H31ClN4O/c1-3-5-17-31(18-6-4-2)25-12-8-11-24(30-25)20-9-7-10-23(19-20)29-26(32)28-22-15-13-21(27)14-16-22/h7-16,19H,3-6,17-18H2,1-2H3,(H2,28,29,32)
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n/an/a 693n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023664
PNG
(CHEMBL3341893)
Show SMILES Clc1cc(Cl)cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1
Show InChI InChI=1S/C22H20Cl2N4O/c23-16-12-17(24)14-19(13-16)26-22(29)25-18-6-3-5-15(11-18)20-7-4-8-21(27-20)28-9-1-2-10-28/h3-8,11-14H,1-2,9-10H2,(H2,25,26,29)
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n/an/a 716n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023693
PNG
(CHEMBL3341870)
Show SMILES CCCCCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C23H25ClN4O/c1-2-3-4-15-25-22-10-6-9-21(28-22)17-7-5-8-20(16-17)27-23(29)26-19-13-11-18(24)12-14-19/h5-14,16H,2-4,15H2,1H3,(H,25,28)(H2,26,27,29)
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n/an/a 867n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023686
PNG
(CHEMBL3341896)
Show SMILES O=C(Nc1cccc(c1)-c1cccc(n1)N1CCCC1)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C26H24N4O/c31-26(28-23-14-13-19-7-1-2-8-20(19)17-23)27-22-10-5-9-21(18-22)24-11-6-12-25(29-24)30-15-3-4-16-30/h1-2,5-14,17-18H,3-4,15-16H2,(H2,27,28,31)
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n/an/a 888n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023701
PNG
(CHEMBL3341871)
Show SMILES CCCCCCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C24H27ClN4O/c1-2-3-4-5-16-26-23-11-7-10-22(29-23)18-8-6-9-21(17-18)28-24(30)27-20-14-12-19(25)13-15-20/h6-15,17H,2-5,16H2,1H3,(H,26,29)(H2,27,28,30)
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n/an/a 1.36E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023672
PNG
(CHEMBL3341884)
Show SMILES CN(C)c1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C24H27N5O/c1-28(2)21-13-11-19(12-14-21)25-24(30)26-20-8-5-7-18(17-20)22-9-6-10-23(27-22)29-15-3-4-16-29/h5-14,17H,3-4,15-16H2,1-2H3,(H2,25,26,30)
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n/an/a 1.64E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023674
PNG
(CHEMBL3341887)
Show SMILES Cc1cc(C)cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1
Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-21(14-17)26-24(29)25-20-8-5-7-19(16-20)22-9-6-10-23(27-22)28-11-3-4-12-28/h5-10,13-16H,3-4,11-12H2,1-2H3,(H2,25,26,29)
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n/an/a 1.88E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023632
PNG
(CHEMBL3341876)
Show SMILES CC(=O)Nc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H17ClN4O2/c1-13(26)22-19-7-3-6-18(25-19)14-4-2-5-17(12-14)24-20(27)23-16-10-8-15(21)9-11-16/h2-12H,1H3,(H,22,25,26)(H2,23,24,27)
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n/an/a 5.12E+3n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023677
PNG
(CHEMBL3341890)
Show SMILES CC(C)c1ccccc1NC(=O)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C25H28N4O/c1-18(2)21-11-3-4-12-23(21)28-25(30)26-20-10-7-9-19(17-20)22-13-8-14-24(27-22)29-15-5-6-16-29/h3-4,7-14,17-18H,5-6,15-16H2,1-2H3,(H2,26,28,30)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023663
PNG
(CHEMBL3341892)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1Cl
Show InChI InChI=1S/C22H20Cl2N4O/c23-18-10-9-17(14-19(18)24)26-22(29)25-16-6-3-5-15(13-16)20-7-4-8-21(27-20)28-11-1-2-12-28/h3-10,13-14H,1-2,11-12H2,(H2,25,26,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023664
PNG
(CHEMBL3341893)
Show SMILES Clc1cc(Cl)cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)c1
Show InChI InChI=1S/C22H20Cl2N4O/c23-16-12-17(24)14-19(13-16)26-22(29)25-18-6-3-5-15(11-18)20-7-4-8-21(27-20)28-9-1-2-10-28/h3-8,11-14H,1-2,9-10H2,(H2,25,26,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023634
PNG
(CHEMBL3341886)
Show SMILES COc1cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc(OC)c1OC
Show InChI InChI=1S/C25H28N4O4/c1-31-21-15-19(16-22(32-2)24(21)33-3)27-25(30)26-18-9-6-8-17(14-18)20-10-7-11-23(28-20)29-12-4-5-13-29/h6-11,14-16H,4-5,12-13H2,1-3H3,(H2,26,27,30)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023685
PNG
(CHEMBL3341895)
Show SMILES O=C(Nc1cccc(c1)-c1cccc(n1)N1CCCC1)Nc1cccc2ccccc12
Show InChI InChI=1S/C26H24N4O/c31-26(29-24-14-6-9-19-8-1-2-12-22(19)24)27-21-11-5-10-20(18-21)23-13-7-15-25(28-23)30-16-3-4-17-30/h1-2,5-15,18H,3-4,16-17H2,(H2,27,29,31)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023631
PNG
(CHEMBL3341872)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(NC3CCCC3)n2)cc1
Show InChI InChI=1S/C23H23ClN4O/c24-17-11-13-19(14-12-17)26-23(29)27-20-8-3-5-16(15-20)21-9-4-10-22(28-21)25-18-6-1-2-7-18/h3-5,8-15,18H,1-2,6-7H2,(H,25,28)(H2,26,27,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB2 receptor stably expressed in CHO-RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization afte...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023630
PNG
(CHEMBL3341862)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCCC2)cc1
Show InChI InChI=1S/C23H23ClN4O/c24-18-10-12-19(13-11-18)25-23(29)26-20-7-4-6-17(16-20)21-8-5-9-22(27-21)28-14-2-1-3-15-28/h4-13,16H,1-3,14-15H2,(H2,25,26,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023633
PNG
(CHEMBL3341880)
Show SMILES O=C(Nc1ccc(cc1)C#N)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C23H21N5O/c24-16-17-9-11-19(12-10-17)25-23(29)26-20-6-3-5-18(15-20)21-7-4-8-22(27-21)28-13-1-2-14-28/h3-12,15H,1-2,13-14H2,(H2,25,26,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50023629
PNG
(CHEMBL3341861)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023675
PNG
(CHEMBL3341888)
Show SMILES Cc1cccc(C)c1NC(=O)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C24H26N4O/c1-17-8-5-9-18(2)23(17)27-24(29)25-20-11-6-10-19(16-20)21-12-7-13-22(26-21)28-14-3-4-15-28/h5-13,16H,3-4,14-15H2,1-2H3,(H2,25,27,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023634
PNG
(CHEMBL3341886)
Show SMILES COc1cc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc(OC)c1OC
Show InChI InChI=1S/C25H28N4O4/c1-31-21-15-19(16-22(32-2)24(21)33-3)27-25(30)26-18-9-6-8-17(14-18)20-10-7-11-23(28-20)29-12-4-5-13-29/h6-11,14-16H,4-5,12-13H2,1-3H3,(H2,26,27,30)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023676
PNG
(CHEMBL3341889)
Show SMILES CCc1ccccc1NC(=O)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C24H26N4O/c1-2-18-9-3-4-12-21(18)27-24(29)25-20-11-7-10-19(17-20)22-13-8-14-23(26-22)28-15-5-6-16-28/h3-4,7-14,17H,2,5-6,15-16H2,1H3,(H2,25,27,29)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023633
PNG
(CHEMBL3341880)
Show SMILES O=C(Nc1ccc(cc1)C#N)Nc1cccc(c1)-c1cccc(n1)N1CCCC1
Show InChI InChI=1S/C23H21N5O/c24-16-17-9-11-19(12-10-17)25-23(29)26-20-6-3-5-18(15-20)21-7-4-8-22(27-21)28-13-1-2-14-28/h3-12,15H,1-2,13-14H2,(H2,25,26,29)
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n/an/an/an/a 55n/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from human CB1 receptor expressed in HEK293 cells after 1 hr by scintillation counting


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023667
PNG
(CHEMBL3341878)
Show SMILES Fc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21FN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/an/an/a 207n/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023665
PNG
(CHEMBL3341759)
Show SMILES CN(C)c1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C20H19ClN4O/c1-25(2)19-8-4-7-18(24-19)14-5-3-6-17(13-14)23-20(26)22-16-11-9-15(21)10-12-16/h3-13H,1-2H3,(H2,22,23,26)
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n/an/an/an/a 663n/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023666
PNG
(CHEMBL3341869)
Show SMILES CCCCNc1cccc(n1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1
Show InChI InChI=1S/C22H23ClN4O/c1-2-3-14-24-21-9-5-8-20(27-21)16-6-4-7-19(15-16)26-22(28)25-18-12-10-17(23)11-13-18/h4-13,15H,2-3,14H2,1H3,(H,24,27)(H2,25,26,28)
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n/an/an/an/a 1.52E+3n/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50023629
PNG
(CHEMBL3341861)
Show SMILES Clc1ccc(NC(=O)Nc2cccc(c2)-c2cccc(n2)N2CCCC2)cc1
Show InChI InChI=1S/C22H21ClN4O/c23-17-9-11-18(12-10-17)24-22(28)25-19-6-3-5-16(15-19)20-7-4-8-21(26-20)27-13-1-2-14-27/h3-12,15H,1-2,13-14H2,(H2,24,25,28)
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n/an/an/an/a 167n/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor stably expressed in RD-HGA16 cells assessed as inhibition of CP55,940-induced calcium mobilization after 15...


J Med Chem 57: 7758-69 (2014)


Article DOI: 10.1021/jm501042u
BindingDB Entry DOI: 10.7270/Q26W9CNX
More data for this
Ligand-Target Pair
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