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Compile Data Set for Download or QSAR

Found 1508 hits with Last Name = 'gnamm' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SYK (aa 342-635)


(Homo sapiens (Human))
BDBM311138
PNG
(example 6.09 on page 559 of WO15017610)
Show SMILES C[C@@H](Oc1cc(cn2ncc(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r|
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n/an/a 0.100n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent




US Patent US10155751 (2018)


BindingDB Entry DOI: 10.7270/Q2PK0J60
More data for this
Ligand-Target Pair
SYK (aa 342-635)


(Homo sapiens (Human))
BDBM311136
PNG
(example 5.20 on page 506 of WO15017610)
Show SMILES C[C@@H](Oc1nc(cn2ncc(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r|
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n/an/a 0.200n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent




US Patent US10155751 (2018)


BindingDB Entry DOI: 10.7270/Q2PK0J60
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173054
PNG
(US9096579, 156)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)C(=O)NCc1ccccn1
Show InChI InChI=1S/C24H22N8O/c1-15-9-18(29-24-26-8-6-19(31-24)21-13-32(2)14-28-21)10-16-11-20(30-22(15)16)23(33)27-12-17-5-3-4-7-25-17/h3-11,13-14,30H,12H2,1-2H3,(H,27,33)(H,26,29,31)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173073
PNG
(US9096579, 175)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)-c1nnco1
Show InChI InChI=1S/C19H16N8O/c1-11-5-13(6-12-7-15(24-17(11)12)18-26-22-10-28-18)23-19-20-4-3-14(25-19)16-8-27(2)9-21-16/h3-10,24H,1-2H3,(H,20,23,25)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172902
PNG
(US9096579, 4)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)C(N)=O
Show InChI InChI=1S/C18H17N7O/c1-10-5-12(6-11-7-14(17(19)26)23-16(10)11)22-18-20-4-3-13(24-18)15-8-25(2)9-21-15/h3-9,23H,1-2H3,(H2,19,26)(H,20,22,24)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172932
PNG
(US9096579, 34)
Show SMILES CN1C(=O)COCC11CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(C)c2[nH]1
Show InChI InChI=1S/C27H30N8O3/c1-17-10-19(30-26-28-7-4-20(32-26)22-13-33(2)16-29-22)11-18-12-21(31-24(17)18)25(37)35-8-5-27(6-9-35)15-38-14-23(36)34(27)3/h4,7,10-13,16,31H,5-6,8-9,14-15H2,1-3H3,(H,28,30,32)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172939
PNG
(US9096579, 41)
Show SMILES CCN(CC)C1CN(C1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(Cl)c2[nH]1
Show InChI InChI=1S/C24H27ClN8O/c1-4-32(5-2)17-11-33(12-17)23(34)20-9-15-8-16(10-18(25)22(15)29-20)28-24-26-7-6-19(30-24)21-13-31(3)14-27-21/h6-10,13-14,17,29H,4-5,11-12H2,1-3H3,(H,26,28,30)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173021
PNG
(US9096579, 123)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)C(=O)NCc1nc2ccncc2[nH]1
Show InChI InChI=1S/C25H22N10O/c1-14-7-16(30-25-27-6-4-18(34-25)21-12-35(2)13-29-21)8-15-9-19(33-23(14)15)24(36)28-11-22-31-17-3-5-26-10-20(17)32-22/h3-10,12-13,33H,11H2,1-2H3,(H,28,36)(H,31,32)(H,27,30,34)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173008
PNG
(US9096579, 110)
Show SMILES CCn1ccc(CNC(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(C)c3[nH]2)n1
Show InChI InChI=1S/C24H25N9O/c1-4-33-8-6-17(31-33)12-26-23(34)20-11-16-10-18(9-15(2)22(16)29-20)28-24-25-7-5-19(30-24)21-13-32(3)14-27-21/h5-11,13-14,29H,4,12H2,1-3H3,(H,26,34)(H,25,28,30)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172947
PNG
(US9096579, 49)
Show SMILES CN1C(=O)COCC11CCN(CC1)C(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(Cl)c2[nH]1
Show InChI InChI=1S/C26H27ClN8O3/c1-33-12-21(29-15-33)19-3-6-28-25(32-19)30-17-9-16-10-20(31-23(16)18(27)11-17)24(37)35-7-4-26(5-8-35)14-38-13-22(36)34(26)2/h3,6,9-12,15,31H,4-5,7-8,13-14H2,1-2H3,(H,28,30,32)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
SYK (aa 342-635)


(Homo sapiens (Human))
BDBM311139
PNG
(example 3B.22 on page 219 of WO15017610)
Show SMILES C[C@@H](Oc1cc(cc2ncn(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r|
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n/an/a 0.800n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent




US Patent US10155751 (2018)


BindingDB Entry DOI: 10.7270/Q2PK0J60
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172943
PNG
(US9096579, 45)
Show SMILES CN1CCN(C2CCN(CC2)C(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(Cl)c3[nH]2)C1=O
Show InChI InChI=1S/C26H28ClN9O2/c1-33-14-22(29-15-33)20-3-6-28-25(32-20)30-17-11-16-12-21(31-23(16)19(27)13-17)24(37)35-7-4-18(5-8-35)36-10-9-34(2)26(36)38/h3,6,11-15,18,31H,4-5,7-10H2,1-2H3,(H,28,30,32)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173019
PNG
(US9096579, 121)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)C(=O)NCc1ccccc1F
Show InChI InChI=1S/C25H22FN7O/c1-15-9-18(30-25-27-8-7-20(32-25)22-13-33(2)14-29-22)10-17-11-21(31-23(15)17)24(34)28-12-16-5-3-4-6-19(16)26/h3-11,13-14,31H,12H2,1-2H3,(H,28,34)(H,27,30,32)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
SYK (aa 342-635)


(Homo sapiens (Human))
BDBM311126
PNG
(US10155751, Example 13)
Show SMILES C[C@@H](Oc1cc(cc2nn(C)c(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r|
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n/an/a 0.900n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent




US Patent US10155751 (2018)


BindingDB Entry DOI: 10.7270/Q2PK0J60
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172927
PNG
(US9096579, 29)
Show SMILES CC(C)n1cnc(c1)-c1ccnc(Nc2cc(Cl)c3[nH]c(cc3c2)C(=O)N2CCN(C)CC2)n1
Show InChI InChI=1S/C24H27ClN8O/c1-15(2)33-13-21(27-14-33)19-4-5-26-24(30-19)28-17-10-16-11-20(29-22(16)18(25)12-17)23(34)32-8-6-31(3)7-9-32/h4-5,10-15,29H,6-9H2,1-3H3,(H,26,28,30)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173073
PNG
(US9096579, 175)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)-c1nnco1
Show InChI InChI=1S/C19H16N8O/c1-11-5-13(6-12-7-15(24-17(11)12)18-26-22-10-28-18)23-19-20-4-3-14(25-19)16-8-27(2)9-21-16/h3-10,24H,1-2H3,(H,20,23,25)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172915
PNG
(US9096579, 17)
Show SMILES CC(C)n1cnc(c1)-c1ccnc(Nc2cc(Cl)c3[nH]c(cc3c2)C(=O)N(C)C)n1
Show InChI InChI=1S/C21H22ClN7O/c1-12(2)29-10-18(24-11-29)16-5-6-23-21(27-16)25-14-7-13-8-17(20(30)28(3)4)26-19(13)15(22)9-14/h5-12,26H,1-4H3,(H,23,25,27)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172906
PNG
(US9096579, 8)
Show SMILES CNC(=O)c1cc2cc(Nc3nccc(n3)-c3cn(C)cn3)cc(C)c2[nH]1
Show InChI InChI=1S/C19H19N7O/c1-11-6-13(7-12-8-15(18(27)20-2)24-17(11)12)23-19-21-5-4-14(25-19)16-9-26(3)10-22-16/h4-10,24H,1-3H3,(H,20,27)(H,21,23,25)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM173010
PNG
(US9096579, 112)
Show SMILES Cc1c(CNC(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(C)c3[nH]2)cnn1C
Show InChI InChI=1S/C24H25N9O/c1-14-7-18(29-24-25-6-5-19(31-24)21-12-32(3)13-27-21)8-16-9-20(30-22(14)16)23(34)26-10-17-11-28-33(4)15(17)2/h5-9,11-13,30H,10H2,1-4H3,(H,26,34)(H,25,29,31)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM172902
PNG
(US9096579, 4)
Show SMILES Cc1cc(Nc2nccc(n2)-c2cn(C)cn2)cc2cc([nH]c12)C(N)=O
Show InChI InChI=1S/C18H17N7O/c1-10-5-12(6-11-7-14(17(19)26)23-16(10)11)22-18-20-4-3-13(24-18)15-8-25(2)9-21-15/h3-9,23H,1-2H3,(H2,19,26)(H,20,22,24)
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Boehringer Ingelheim International GmbH

US Patent


Assay Description
Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...


US Patent US9096579 (2015)


BindingDB Entry DOI: 10.7270/Q2F76B9H
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310019
PNG
(US9657015, Example 12 | US9657015, Example 12.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310019
PNG
(US9657015, Example 12 | US9657015, Example 12.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310019
PNG
(US9657015, Example 12 | US9657015, Example 12.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310019
PNG
(US9657015, Example 12 | US9657015, Example 12.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310019
PNG
(US9657015, Example 12 | US9657015, Example 12.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310046
PNG
(US9657015, Example 15 | US9657015, Example 15.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCN(C)C2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310046
PNG
(US9657015, Example 15 | US9657015, Example 15.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCN(C)C2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310046
PNG
(US9657015, Example 15 | US9657015, Example 15.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCN(C)C2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310046
PNG
(US9657015, Example 15 | US9657015, Example 15.1 | ...)
Show SMILES CNC(=O)CN1C(C2=C(CCN(C)C2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:7|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310053
PNG
(US9657015, Example 16)
Show SMILES CNC(=O)N1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C#N |t:6|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310054
PNG
(BDBM310055 | US9657015, Example 17)
Show SMILES OCCNC(=O)N1CCC2=C(C(NC(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2)C#N)C1=O |t:9|
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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310059
PNG
(US9657015, Example 22)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1Br)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310060
PNG
(US9657015, Example 23)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=O)NC(C2=C1CCNC2=O)c1ccc(cc1-c1cnco1)C#N |c:16|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310061
PNG
(US9657015, Example 24)
Show SMILES Cn1cc(cn1)-c1cc(ccc1C1NC(=O)N(C2=C1C(=O)NCC2)c1cccc(c1)C(F)(F)F)C#N |c:19|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310062
PNG
(US9657015, Example 25 | US9657015, Example 30A)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1cnco1)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310063
PNG
(US9657015, Example 26)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1cnn(C)c1)C#N |t:3|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310064
PNG
(US9657015, Example 27)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=O)NC(C2=C1CCNC2=O)c1ccc(cc1C(F)(F)F)C#N |c:16|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310065
PNG
(US9657015, Example 28)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1C(F)(F)F)C#N |t:3|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310066
PNG
(US9657015, Example 29)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1CO)C#N |t:3|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310062
PNG
(US9657015, Example 25 | US9657015, Example 30A)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1cnco1)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310069
PNG
(US9657015, Example 31A)
Show SMILES CN1[C@@H](C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1cnn(C)c1)C#N |r,t:3|
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Boehringer Ingelheim International GmbH

US Patent




US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310071
PNG
(US9657015, Example 32A)
Show SMILES CN1[C@@H](C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1CO)C#N |r,t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310073
PNG
(US9657015, Example 33)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1ccncc1)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310074
PNG
(US9657015, Example 34)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1cccnc1)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310075
PNG
(US9657015, Example 35)
Show SMILES CN1C(C2=C(CCNC2=O)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1-c1ccncn1)C#N |t:3|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310076
PNG
(US9657015, Example 36 | US9657015, Example 36.1 | ...)
Show SMILES CN1CCC2=C(C(N(C)C(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2-c2cnn(C)c2)C#N)C1=O |t:4|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310080
PNG
(US9657015, Example 37)
Show SMILES CN1CCC2=C(C(N(C)C(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2-c2cnco2)C#N)C1=O |t:4|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310081
PNG
(US9657015, Example 38)
Show SMILES CN1CCC2=C(C(N(C)C(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2CO)C#N)C1=O |t:4|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310082
PNG
(US9657015, Example 39 | US9657015, Example 39.1 | ...)
Show SMILES CN1CCC2=C(C(N(C)C(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2C(N)=O)C#N)C1=O |t:4|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM310082
PNG
(US9657015, Example 39 | US9657015, Example 39.1 | ...)
Show SMILES CN1CCC2=C(C(N(C)C(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2C(N)=O)C#N)C1=O |t:4|
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Boehringer Ingelheim International GmbH

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US Patent US9657015 (2017)


BindingDB Entry DOI: 10.7270/Q28G8NRP
More data for this
Ligand-Target Pair
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