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Compile Data Set for Download or QSAR

Found 187 hits with Last Name = 'goh' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207038
PNG
(CHEMBL3961596)
Show SMILES CNCC1Cc2cc3ccn(c3cc12)S(=O)(=O)c1cccc2ccccc12
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1n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50206981
PNG
(CHEMBL3948819)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1cccc2ccccc12
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1n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207046
PNG
(CHEMBL3929918)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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1.60n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207039
PNG
(CHEMBL3890882)
Show SMILES CN[C@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))
BDBM18793
PNG
(6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]...)
Show SMILES CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(Cl)c(Cl)cc1Cl |t:3,6|
Show InChI InChI=1S/C14H18Cl3N5O2/c1-14(2)21-12(18)20-13(19)22(14)24-5-3-4-23-11-7-9(16)8(15)6-10(11)17/h6-7H,3-5H2,1-2H3,(H4,18,19,20,21)
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7.70n/an/an/an/an/an/an/an/a



Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assay


Antimicrob Agents Chemother 54: 2603-10 (2010)


Article DOI: 10.1128/AAC.01526-09
BindingDB Entry DOI: 10.7270/Q2VX0GQW
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207042
PNG
(CHEMBL3895173)
Show SMILES CN[C@@H]1[C@H](CCO)c2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1 |r|
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7.90n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207043
PNG
(CHEMBL3959964)
Show SMILES CN[C@@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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10n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))
BDBM50035483
PNG
(5-Chloro-N*6*-(2,5-dimethoxy-benzyl)-quinazoline-2...)
Show SMILES COc1ccc(OC)c(CNc2ccc3nc(N)nc(N)c3c2Cl)c1
Show InChI InChI=1S/C17H18ClN5O2/c1-24-10-3-6-13(25-2)9(7-10)8-21-12-5-4-11-14(15(12)18)16(19)23-17(20)22-11/h3-7,21H,8H2,1-2H3,(H4,19,20,22,23)
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10.2n/an/an/an/an/an/an/an/a



Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assay


Antimicrob Agents Chemother 54: 2603-10 (2010)


Article DOI: 10.1128/AAC.01526-09
BindingDB Entry DOI: 10.7270/Q2VX0GQW
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207045
PNG
(CHEMBL3944687)
Show SMILES CN(C)[C@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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13n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50206983
PNG
(CHEMBL3908917)
Show SMILES CN[C@H]1[C@@H](CCO)c2c1ccc1n(ccc21)S(=O)(=O)c1ccccc1 |r|
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25n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))
BDBM18512
PNG
(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Show SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
Show InChI InChI=1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
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30.8n/an/an/an/an/an/an/an/a



Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assay


Antimicrob Agents Chemother 54: 2603-10 (2010)


Article DOI: 10.1128/AAC.01526-09
BindingDB Entry DOI: 10.7270/Q2VX0GQW
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207044
PNG
(CHEMBL3916787)
Show SMILES CN(C)[C@@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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40n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207037
PNG
(CHEMBL3889852)
Show SMILES [H][C@]12CCNCC[C@@]1([H])c1c2ccc2n(ccc12)S(=O)(=O)c1ccccc1 |r|
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50n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
Dihydrofolate reductase


(Homo sapiens (Human))
BDBM18792
PNG
(1-(4-chlorophenyl)-6,6-dimethyl-1,6-dihydro-1,3,5-...)
Show SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1 |t:3,6|
Show InChI InChI=1S/C11H14ClN5/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h3-6H,1-2H3,(H4,13,14,15,16)
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55.6n/an/an/an/an/an/an/an/a



Kenya Medical Research Institute/Wellcome Trust Collaborative Research Program

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant DHFR expressed in Escherichia coli BL21(DE3) by competitive binding assay


Antimicrob Agents Chemother 54: 2603-10 (2010)


Article DOI: 10.1128/AAC.01526-09
BindingDB Entry DOI: 10.7270/Q2VX0GQW
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207047
PNG
(CHEMBL3910287)
Show SMILES CN(CCc1ccc(NC(C)=O)cc1)CC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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79n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50206982
PNG
(CHEMBL3971039)
Show SMILES CN[C@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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126n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207049
PNG
(CHEMBL3919497)
Show SMILES CN(C)[C@@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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126n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50206980
PNG
(CHEMBL3979230)
Show SMILES CN[C@@H]1[C@@H](CCO)c2c1ccc1n(ccc21)S(=O)(=O)c1ccccc1 |r|
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158n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207041
PNG
(CHEMBL3938498)
Show SMILES [H][C@@]12CCNCC[C@]1([H])c1cc3n(ccc3cc21)S(=O)(=O)c1ccccc1 |r|
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158n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207040
PNG
(CHEMBL3963688)
Show SMILES CN[C@@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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158n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207036
PNG
(CHEMBL3966484)
Show SMILES CN[C@@H]1[C@@H](CCO)c2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1 |r|
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200n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207040
PNG
(CHEMBL3963688)
Show SMILES CN[C@@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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251n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50206981
PNG
(CHEMBL3948819)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1cccc2ccccc12
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251n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207047
PNG
(CHEMBL3910287)
Show SMILES CN(CCc1ccc(NC(C)=O)cc1)CC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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251n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207048
PNG
(CHEMBL3947289)
Show SMILES CN(C)[C@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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316n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50207049
PNG
(CHEMBL3919497)
Show SMILES CN(C)[C@@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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316n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human 5-HT6R expressed in CHO cell membranes by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207044
PNG
(CHEMBL3916787)
Show SMILES CN(C)[C@@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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398n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207047
PNG
(CHEMBL3910287)
Show SMILES CN(CCc1ccc(NC(C)=O)cc1)CC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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501n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207048
PNG
(CHEMBL3947289)
Show SMILES CN(C)[C@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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631n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207037
PNG
(CHEMBL3889852)
Show SMILES [H][C@]12CCNCC[C@@]1([H])c1c2ccc2n(ccc12)S(=O)(=O)c1ccccc1 |r|
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794n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207038
PNG
(CHEMBL3961596)
Show SMILES CNCC1Cc2cc3ccn(c3cc12)S(=O)(=O)c1cccc2ccccc12
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794n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50206981
PNG
(CHEMBL3948819)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1cccc2ccccc12
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1.00E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50206982
PNG
(CHEMBL3971039)
Show SMILES CN[C@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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1.00E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207037
PNG
(CHEMBL3889852)
Show SMILES [H][C@]12CCNCC[C@@]1([H])c1c2ccc2n(ccc12)S(=O)(=O)c1ccccc1 |r|
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1.00E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207045
PNG
(CHEMBL3944687)
Show SMILES CN(C)[C@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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1.26E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207046
PNG
(CHEMBL3929918)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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1.26E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50206980
PNG
(CHEMBL3979230)
Show SMILES CN[C@@H]1[C@@H](CCO)c2c1ccc1n(ccc21)S(=O)(=O)c1ccccc1 |r|
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1.26E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207043
PNG
(CHEMBL3959964)
Show SMILES CN[C@@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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1.26E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207036
PNG
(CHEMBL3966484)
Show SMILES CN[C@@H]1[C@@H](CCO)c2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1 |r|
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1.26E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207039
PNG
(CHEMBL3890882)
Show SMILES CN[C@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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2.00E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207046
PNG
(CHEMBL3929918)
Show SMILES CNCC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
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2.00E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207038
PNG
(CHEMBL3961596)
Show SMILES CNCC1Cc2cc3ccn(c3cc12)S(=O)(=O)c1cccc2ccccc12
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2.51E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207041
PNG
(CHEMBL3938498)
Show SMILES [H][C@@]12CCNCC[C@]1([H])c1cc3n(ccc3cc21)S(=O)(=O)c1ccccc1 |r|
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3.16E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207040
PNG
(CHEMBL3963688)
Show SMILES CN[C@@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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6.31E+3n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50206983
PNG
(CHEMBL3908917)
Show SMILES CN[C@H]1[C@@H](CCO)c2c1ccc1n(ccc21)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50206982
PNG
(CHEMBL3971039)
Show SMILES CN[C@H]1[C@@H](CCO)c2cc3ccn(c3cc12)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207042
PNG
(CHEMBL3895173)
Show SMILES CN[C@@H]1[C@H](CCO)c2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207044
PNG
(CHEMBL3916787)
Show SMILES CN(C)[C@@H]1[C@H](CCO)c2cc3n(ccc3cc12)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50207042
PNG
(CHEMBL3895173)
Show SMILES CN[C@@H]1[C@H](CCO)c2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D3 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation counting


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50207041
PNG
(CHEMBL3938498)
Show SMILES [H][C@@]12CCNCC[C@]1([H])c1cc3n(ccc3cc21)S(=O)(=O)c1ccccc1 |r|
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<1.00E+4n/an/an/an/an/an/an/an/a



Universit£ de Montr£al

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyl-spiperone from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by radioligand binding assay


Bioorg Med Chem 25: 38-52 (2017)


Article DOI: 10.1016/j.bmc.2016.10.010
BindingDB Entry DOI: 10.7270/Q2VT1V3Q
More data for this
Ligand-Target Pair
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