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Compile Data Set for Download or QSAR

Found 463 hits with Last Name = 'hayhow' and Initial = 'tg'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone acetyltransferase KAT2A/KAT2B


(Homo sapiens (Human))
BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
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1.30n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2A/KAT2B


(Homo sapiens (Human))
BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
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1.30n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Histone acetyltransferase KAT2A/KAT2B


(Homo sapiens (Human))
BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
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1.40n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Histone acetyltransferase KAT2A/KAT2B


(Homo sapiens (Human))
BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
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1.40n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50259548
PNG
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O
Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1
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2.51n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50183182
PNG
(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)
Show SMILES OC(=O)c1cccc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C26H19ClO3/c27-21-13-14-25(30-17-18-7-2-1-3-8-18)24(16-21)23-12-5-4-11-22(23)19-9-6-10-20(15-19)26(28)29/h1-16H,17H2,(H,28,29)
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31.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at EP1 receptor assessed as calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412231
PNG
(CHEMBL520438)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CO)cc1
Show InChI InChI=1S/C26H24ClN3O3/c1-18-13-24(26(32)28-23-10-7-19(16-31)8-11-23)29-30(18)15-21-14-22(27)9-12-25(21)33-17-20-5-3-2-4-6-20/h2-14,31H,15-17H2,1H3,(H,28,32)
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39.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412241
PNG
(CHEMBL495091)
Show SMILES CCN1CCc2ccc(cc2CC1)C(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCC(C)C)n1
Show InChI InChI=1S/C28H35ClN4O2/c1-5-32-12-10-21-6-7-23(15-22(21)11-13-32)28(34)30-27-14-20(4)33(31-27)17-24-16-25(29)8-9-26(24)35-18-19(2)3/h6-9,14-16,19H,5,10-13,17-18H2,1-4H3,(H,30,31,34)
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50.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412239
PNG
(CHEMBL492237)
Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1
Show InChI InChI=1S/C24H29ClN4O2/c1-16(2)15-31-23-10-7-20(25)12-19(23)14-29-17(3)11-22(28-29)24(30)27-21-8-5-18(6-9-21)13-26-4/h5-12,16,26H,13-15H2,1-4H3,(H,27,30)
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79.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412232
PNG
(CHEMBL523216)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN(CCO)CCO)cc1
Show InChI InChI=1S/C27H35ClN4O4/c1-19(2)18-36-26-9-6-23(28)15-22(26)17-32-20(3)14-25(30-32)27(35)29-24-7-4-21(5-8-24)16-31(10-12-33)11-13-34/h4-9,14-15,19,33-34H,10-13,16-18H2,1-3H3,(H,29,35)
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79.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412224
PNG
(CHEMBL479591)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C30H31ClN4O3/c1-22-17-28(30(36)32-27-10-7-23(8-11-27)19-34-13-15-37-16-14-34)33-35(22)20-25-18-26(31)9-12-29(25)38-21-24-5-3-2-4-6-24/h2-12,17-18H,13-16,19-21H2,1H3,(H,32,36)
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79.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Bromodomain and PHD finger-containing protein 3


(Homo sapiens (Human))
BDBM50234923
PNG
(CHEMBL4069412)
Show SMILES CN1C[C@@H](C[C@@H](C1)c1ccccc1)Nc1cnn(C)c(=O)c1Br |r|
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100n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412209
PNG
(CHEMBL494466)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc(cc2)C2CCCN2)cc1C
Show InChI InChI=1S/C26H31ClN4O2/c1-17(2)16-33-24-11-10-22(27)14-21(24)15-31-18(3)13-25(30-31)29-26(32)20-8-6-19(7-9-20)23-5-4-12-28-23/h6-11,13-14,17,23,28H,4-5,12,15-16H2,1-3H3,(H,29,30,32)
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100n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412233
PNG
(CHEMBL495107)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CNCCO)cc1
Show InChI InChI=1S/C25H31ClN4O3/c1-17(2)16-33-24-9-6-21(26)13-20(24)15-30-18(3)12-23(29-30)25(32)28-22-7-4-19(5-8-22)14-27-10-11-31/h4-9,12-13,17,27,31H,10-11,14-16H2,1-3H3,(H,28,32)
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100n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412225
PNG
(CHEMBL480789)
Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C27H27ClN4O2/c1-19-14-25(27(33)30-24-11-8-20(9-12-24)16-29-2)31-32(19)17-22-15-23(28)10-13-26(22)34-18-21-6-4-3-5-7-21/h3-15,29H,16-18H2,1-2H3,(H,30,33)
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126n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412208
PNG
(CHEMBL493254)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc3CNCCc3c2)cc1C
Show InChI InChI=1S/C25H29ClN4O2/c1-16(2)15-32-23-7-6-22(26)12-21(23)14-30-17(3)10-24(29-30)28-25(31)19-4-5-20-13-27-9-8-18(20)11-19/h4-7,10-12,16,27H,8-9,13-15H2,1-3H3,(H,28,29,31)
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126n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412215
PNG
(CHEMBL481870)
Show SMILES CCNCc1ccc(cc1)C(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCC(C)C)n1
Show InChI InChI=1S/C25H31ClN4O2/c1-5-27-14-19-6-8-20(9-7-19)25(31)28-24-12-18(4)30(29-24)15-21-13-22(26)10-11-23(21)32-16-17(2)3/h6-13,17,27H,5,14-16H2,1-4H3,(H,28,29,31)
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158n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412213
PNG
(CHEMBL481689)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc(CN3CCCC3)cc2)cc1C
Show InChI InChI=1S/C27H33ClN4O2/c1-19(2)18-34-25-11-10-24(28)15-23(25)17-32-20(3)14-26(30-32)29-27(33)22-8-6-21(7-9-22)16-31-12-4-5-13-31/h6-11,14-15,19H,4-5,12-13,16-18H2,1-3H3,(H,29,30,33)
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158n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50259548
PNG
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O
Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1
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316n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to TP receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50259548
PNG
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O
Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1
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2.00E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Activity at EP3 receptor by FLIPR method


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413672
PNG
(CHEMBL516324)
Show SMILES CCCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C30H26ClNO4/c1-2-8-29(33)32-24-16-21(15-22(17-24)30(34)35)25-11-6-7-12-26(25)27-18-23(31)13-14-28(27)36-19-20-9-4-3-5-10-20/h3-7,9-18H,2,8,19H2,1H3,(H,32,33)(H,34,35)
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n/an/a 2n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413667
PNG
(CHEMBL514574)
Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(F)cc1F
Show InChI InChI=1S/C25H16ClF2NO3/c26-16-9-11-24(32-14-15-8-10-17(27)13-21(15)28)20(12-16)18-4-1-2-5-19(18)22-6-3-7-23(29-22)25(30)31/h1-13H,14H2,(H,30,31)
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n/an/a 3.98n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413670
PNG
(CHEMBL458452)
Show SMILES COCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H24ClNO5/c1-35-18-28(32)31-23-14-20(13-21(15-23)29(33)34)24-9-5-6-10-25(24)26-16-22(30)11-12-27(26)36-17-19-7-3-2-4-8-19/h2-16H,17-18H2,1H3,(H,31,32)(H,33,34)
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n/an/a 3.98n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50419265
PNG
(CHEMBL1835069)
Show SMILES Cc1cccc(Nc2nc(N[C@@H]3CC(F)(F)CC[C@@H]3N)ncc2C(N)=O)c1 |r|
Show InChI InChI=1S/C18H22F2N6O/c1-10-3-2-4-11(7-10)24-16-12(15(22)27)9-23-17(26-16)25-14-8-18(19,20)6-5-13(14)21/h2-4,7,9,13-14H,5-6,8,21H2,1H3,(H2,22,27)(H2,23,24,25,26)/t13-,14+/m0/s1
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n/an/a 4n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assay


Bioorg Med Chem Lett 21: 6188-94 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.082
BindingDB Entry DOI: 10.7270/Q2XD12ZW
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413668
PNG
(CHEMBL457142)
Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(F)cc1
Show InChI InChI=1S/C25H17ClFNO3/c26-17-10-13-24(31-15-16-8-11-18(27)12-9-16)21(14-17)19-4-1-2-5-20(19)22-6-3-7-23(28-22)25(29)30/h1-14H,15H2,(H,29,30)
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n/an/a 5.01n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412237
PNG
(CHEMBL492238)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN(C)C)cc1
Show InChI InChI=1S/C25H31ClN4O2/c1-17(2)16-32-24-11-8-21(26)13-20(24)15-30-18(3)12-23(28-30)25(31)27-22-9-6-19(7-10-22)14-29(4)5/h6-13,17H,14-16H2,1-5H3,(H,27,31)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50396073
PNG
(CHEMBL1235110)
Show SMILES Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)c1 |r|
Show InChI InChI=1S/C18H24N6O/c1-11-5-4-6-12(9-11)22-17-13(16(20)25)10-21-18(24-17)23-15-8-3-2-7-14(15)19/h4-6,9-10,14-15H,2-3,7-8,19H2,1H3,(H2,20,25)(H2,21,22,23,24)/t14-,15+/m0/s1
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n/an/a 6.30n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assay


Bioorg Med Chem Lett 21: 6188-94 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.082
BindingDB Entry DOI: 10.7270/Q2XD12ZW
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413673
PNG
(CHEMBL456496)
Show SMILES CCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C29H24ClNO4/c1-2-28(32)31-23-15-20(14-21(16-23)29(33)34)24-10-6-7-11-25(24)26-17-22(30)12-13-27(26)35-18-19-8-4-3-5-9-19/h3-17H,2,18H2,1H3,(H,31,32)(H,33,34)
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n/an/a 6.31n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412231
PNG
(CHEMBL520438)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CO)cc1
Show InChI InChI=1S/C26H24ClN3O3/c1-18-13-24(26(32)28-23-10-7-19(16-31)8-11-23)29-30(18)15-21-14-22(27)9-12-25(21)33-17-20-5-3-2-4-6-20/h2-14,31H,15-17H2,1H3,(H,28,32)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412236
PNG
(CHEMBL494282)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN2CCCC2)cc1
Show InChI InChI=1S/C27H33ClN4O2/c1-19(2)18-34-26-11-8-23(28)15-22(26)17-32-20(3)14-25(30-32)27(33)29-24-9-6-21(7-10-24)16-31-12-4-5-13-31/h6-11,14-15,19H,4-5,12-13,16-18H2,1-3H3,(H,29,33)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412235
PNG
(CHEMBL493065)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C28H35ClN4O2/c1-20(2)19-35-27-12-9-24(29)16-23(27)18-33-21(3)15-26(31-33)28(34)30-25-10-7-22(8-11-25)17-32-13-5-4-6-14-32/h7-12,15-16,20H,4-6,13-14,17-19H2,1-3H3,(H,30,34)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412238
PNG
(CHEMBL523158)
Show SMILES CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1
Show InChI InChI=1S/C25H31ClN4O2/c1-5-27-14-19-6-9-22(10-7-19)28-25(31)23-12-18(4)30(29-23)15-20-13-21(26)8-11-24(20)32-16-17(2)3/h6-13,17,27H,5,14-16H2,1-4H3,(H,28,31)
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n/an/a 7.94n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412229
PNG
(CHEMBL480950)
Show SMILES CN(C)Cc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C28H29ClN4O2/c1-20-15-26(28(34)30-25-12-9-21(10-13-25)17-32(2)3)31-33(20)18-23-16-24(29)11-14-27(23)35-19-22-7-5-4-6-8-22/h4-16H,17-19H2,1-3H3,(H,30,34)
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n/an/a 7.94n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412234
PNG
(CHEMBL523679)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C27H33ClN4O3/c1-19(2)18-35-26-9-6-23(28)15-22(26)17-32-20(3)14-25(30-32)27(33)29-24-7-4-21(5-8-24)16-31-10-12-34-13-11-31/h4-9,14-15,19H,10-13,16-18H2,1-3H3,(H,29,33)
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n/an/a 7.94n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412239
PNG
(CHEMBL492237)
Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1
Show InChI InChI=1S/C24H29ClN4O2/c1-16(2)15-31-23-10-7-20(25)12-19(23)14-29-17(3)11-22(28-29)24(30)27-21-8-5-18(6-9-21)13-26-4/h5-12,16,26H,13-15H2,1-4H3,(H,27,30)
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n/an/a 7.94n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413674
PNG
(CHEMBL456495)
Show SMILES CC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C28H22ClNO4/c1-18(31)30-23-14-20(13-21(15-23)28(32)33)24-9-5-6-10-25(24)26-16-22(29)11-12-27(26)34-17-19-7-3-2-4-8-19/h2-16H,17H2,1H3,(H,30,31)(H,32,33)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412224
PNG
(CHEMBL479591)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C30H31ClN4O3/c1-22-17-28(30(36)32-27-10-7-23(8-11-27)19-34-13-15-37-16-14-34)33-35(22)20-25-18-26(31)9-12-29(25)38-21-24-5-3-2-4-6-24/h2-12,17-18H,13-16,19-21H2,1H3,(H,32,36)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412226
PNG
(CHEMBL404525)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C([O-])=O
Show InChI InChI=1S/C19H17ClN2O3/c1-13-9-17(19(23)24)21-22(13)11-15-10-16(20)7-8-18(15)25-12-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,23,24)/p-1
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50419258
PNG
(CHEMBL1835070)
Show SMILES Cc1ccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)cc1 |r|
Show InChI InChI=1S/C18H24N6O/c1-11-6-8-12(9-7-11)22-17-13(16(20)25)10-21-18(24-17)23-15-5-3-2-4-14(15)19/h6-10,14-15H,2-5,19H2,1H3,(H2,20,25)(H2,21,22,23,24)/t14-,15+/m0/s1
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GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assay


Bioorg Med Chem Lett 21: 6188-94 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.082
BindingDB Entry DOI: 10.7270/Q2XD12ZW
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413671
PNG
(CHEMBL458448)
Show SMILES CC(C)C(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C30H26ClNO4/c1-19(2)29(33)32-24-15-21(14-22(16-24)30(34)35)25-10-6-7-11-26(25)27-17-23(31)12-13-28(27)36-18-20-8-4-3-5-9-20/h3-17,19H,18H2,1-2H3,(H,32,33)(H,34,35)
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GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413669
PNG
(CHEMBL515981)
Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1
Show InChI InChI=1S/C25H18ClNO3/c26-18-13-14-24(30-16-17-7-2-1-3-8-17)21(15-18)19-9-4-5-10-20(19)22-11-6-12-23(27-22)25(28)29/h1-15H,16H2,(H,28,29)
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n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412227
PNG
(CHEMBL480181)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C31H33ClN4O2/c1-23-18-29(31(37)33-28-13-10-24(11-14-28)20-35-16-6-3-7-17-35)34-36(23)21-26-19-27(32)12-15-30(26)38-22-25-8-4-2-5-9-25/h2,4-5,8-15,18-19H,3,6-7,16-17,20-22H2,1H3,(H,33,37)
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412230
PNG
(CHEMBL480790)
Show SMILES CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C28H29ClN4O2/c1-3-30-17-21-9-12-25(13-10-21)31-28(34)26-15-20(2)33(32-26)18-23-16-24(29)11-14-27(23)35-19-22-7-5-4-6-8-22/h4-16,30H,3,17-19H2,1-2H3,(H,31,34)
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412225
PNG
(CHEMBL480789)
Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1
Show InChI InChI=1S/C27H27ClN4O2/c1-19-14-25(27(33)30-24-11-8-20(9-12-24)16-29-2)31-32(19)17-22-15-23(28)10-13-26(22)34-18-21-6-4-3-5-7-21/h3-15,29H,16-18H2,1-2H3,(H,30,33)
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412216
PNG
(CHEMBL447709)
Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc(CO)cc2)cc1C
Show InChI InChI=1S/C23H26ClN3O3/c1-15(2)14-30-21-9-8-20(24)11-19(21)12-27-16(3)10-22(26-27)25-23(29)18-6-4-17(13-28)5-7-18/h4-11,15,28H,12-14H2,1-3H3,(H,25,26,29)
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50412228
PNG
(CHEMBL479989)
Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCCC2)cc1
Show InChI InChI=1S/C30H31ClN4O2/c1-22-17-28(30(36)32-27-12-9-23(10-13-27)19-34-15-5-6-16-34)33-35(22)20-25-18-26(31)11-14-29(25)37-21-24-7-3-2-4-8-24/h2-4,7-14,17-18H,5-6,15-16,19-21H2,1H3,(H,32,36)
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells


Bioorg Med Chem Lett 18: 4027-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.118
BindingDB Entry DOI: 10.7270/Q2NC62F7
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50413663
PNG
(CHEMBL466549)
Show SMILES [O-]C(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1c(F)cc(F)cc1F
Show InChI InChI=1S/C25H15ClF3NO3/c26-14-8-9-24(33-13-19-20(28)11-15(27)12-21(19)29)18(10-14)16-4-1-2-5-17(16)22-6-3-7-23(30-22)25(31)32/h1-12H,13H2,(H,31,32)/p-1
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Prostanoid EP1 receptor


(Rattus norvegicus (Rat))
BDBM50259548
PNG
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)
Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O
Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1
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n/an/a 12.6n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Binding affinity to rat EP1 receptor


Bioorg Med Chem Lett 19: 497-501 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM50419256
PNG
(CHEMBL1835065 | US9579320, Example 302)
Show SMILES Cc1cccc(Nc2nc(N[C@@H]3CCOC[C@@H]3N)ncc2C(N)=O)c1 |r|
Show InChI InChI=1S/C17H22N6O2/c1-10-3-2-4-11(7-10)21-16-12(15(19)24)8-20-17(23-16)22-14-5-6-25-9-13(14)18/h2-4,7-8,13-14H,5-6,9,18H2,1H3,(H2,19,24)(H2,20,21,22,23)/t13-,14+/m0/s1
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assay


Bioorg Med Chem Lett 21: 6188-94 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.082
BindingDB Entry DOI: 10.7270/Q2XD12ZW
More data for this
Ligand-Target Pair
Histone acetyltransferase KAT2A/KAT2B


(Homo sapiens (Human))
BDBM50234932
PNG
(CHEMBL4103402 | US10239861, Example 20)
Show SMILES CC(C)C[C@H]1C[C@H](CN(C)C1)Nc1cnn(C)c(=O)c1Cl |r|
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL




J Med Chem 60: 695-709 (2017)


BindingDB Entry DOI: 10.7270/Q2W09863
More data for this
Ligand-Target Pair
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