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Compile Data Set for Download or QSAR

Found 104 hits with Last Name = 'hegde' and Initial = 'lg'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50152456
PNG
((S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]...)
Show SMILES COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC |t:3|
Show InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1
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0.25n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50152456
PNG
((S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]...)
Show SMILES COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC |t:3|
Show InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1
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0.25n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219036
PNG
(CHEMBL388440 | N-{3-[1-(3-{[hydroxy(diphenyl)acety...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(O)(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C33H41N3O3/c1-24(2)31(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-32(38)33(39,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,39H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)
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0.600n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219040
PNG
(CHEMBL429464 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C33H39F2N3O2/c1-22(2)32(39)37-29-14-5-23(3)30(21-29)24-15-19-38(20-16-24)18-4-17-36-33(40)31(25-6-10-27(34)11-7-25)26-8-12-28(35)13-9-26/h5-14,21-22,24,31H,4,15-20H2,1-3H3,(H,36,40)(H,37,39)
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0.620n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219026
PNG
(CHEMBL243338 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C32H37F2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38)
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1.40n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219035
PNG
(CHEMBL243355 | N-{5-[1-(3-{[bis(4-fluorophenyl)ace...)
Show SMILES CC(C)C(=O)Nc1cc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(F)cc1F
Show InChI InChI=1S/C32H35F4N3O2/c1-20(2)31(40)38-29-18-26(27(35)19-28(29)36)21-12-16-39(17-13-21)15-3-14-37-32(41)30(22-4-8-24(33)9-5-22)23-6-10-25(34)11-7-23/h4-11,18-21,30H,3,12-17H2,1-2H3,(H,37,41)(H,38,40)
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1.80n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219047
PNG
(CHEMBL245231 | N-(3-(1-(4-(3,4-difluorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
Show InChI InChI=1S/C28H30F2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33)
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1.80n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219029
PNG
(CHEMBL390679 | N-{3-[1-(2-diphenylacetylamino-ethy...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35)
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1.90n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219037
PNG
(1-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C32H44FN3O2/c1-23(2)30(37)35-28-13-8-24(3)29(22-28)25-14-20-36(21-15-25)19-7-18-34-31(38)32(16-5-4-6-17-32)26-9-11-27(33)12-10-26/h8-13,22-23,25H,4-7,14-21H2,1-3H3,(H,34,38)(H,35,37)
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1.90n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219023
PNG
(CHEMBL243138 | N-{3-[1-(3-diphenylacetylamino-prop...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C32H39N3O2/c1-24(2)31(36)34-29-16-9-15-28(23-29)25-17-21-35(22-18-25)20-10-19-33-32(37)30(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-9,11-16,23-25,30H,10,17-22H2,1-2H3,(H,33,37)(H,34,36)
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1.90n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219053
PNG
(CHEMBL242004 | N-(3-{1-4-(3,4-difluorophenoxy)benz...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
Show InChI InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-23-7-4-20(3)26(16-23)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-27(30)28(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34)
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2.20n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219044
PNG
(CHEMBL243128 | N-{3-[1-(3-{[bis(4-chlorophenyl)ace...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C32H37Cl2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38)
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2.40n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219025
PNG
(CHEMBL243578 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...)
Show SMILES CC(C)C(=O)Nc1c(F)cc(F)c(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1F
Show InChI InChI=1S/C32H34F5N3O2/c1-19(2)31(41)39-30-26(36)18-25(35)28(29(30)37)22-12-16-40(17-13-22)15-3-14-38-32(42)27(20-4-8-23(33)9-5-20)21-6-10-24(34)11-7-21/h4-11,18-19,22,27H,3,12-17H2,1-2H3,(H,38,42)(H,39,41)
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2.90n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219042
PNG
(CHEMBL242689 | N-[3-(1-{3-[(diphenylacetyl)amino]p...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C33H41N3O2/c1-24(2)32(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)
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3n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219031
PNG
(1-(4-fluorophenyl)-N-(3-{4-[5-(isobutylamino)-2-me...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCC2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C31H42FN3O2/c1-22(2)29(36)34-27-12-7-23(3)28(21-27)24-13-19-35(20-14-24)18-6-17-33-30(37)31(15-4-5-16-31)25-8-10-26(32)11-9-25/h7-12,21-22,24H,4-6,13-20H2,1-3H3,(H,33,37)(H,34,36)
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3.80n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219062
PNG
(CHEMBL394569 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C25H31ClN2O2/c1-18(2)25(30)27-23-6-3-5-21(17-23)19-12-15-28(16-13-19)14-4-7-24(29)20-8-10-22(26)11-9-20/h3,5-6,8-11,17-19H,4,7,12-16H2,1-2H3,(H,27,30)
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5n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219064
PNG
(CHEMBL245010 | N-(3-{1-[4-(4-chlorophenoxy)benzyl]...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)CC1
Show InChI InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-5-3-4-23(18-25)22-14-16-31(17-15-22)19-21-6-10-26(11-7-21)33-27-12-8-24(29)9-13-27/h3-13,18,20,22H,14-17,19H2,1-2H3,(H,30,32)
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5.30n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219032
PNG
(CHEMBL242902 | N-(3-{4-[3-(isobutyrylamino)phenyl]...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(C)(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C33H41N3O2/c1-25(2)31(37)35-30-17-10-12-27(24-30)26-18-22-36(23-19-26)21-11-20-34-32(38)33(3,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24-26H,11,18-23H2,1-3H3,(H,34,38)(H,35,37)
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7.5n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219050
PNG
(CHEMBL389129 | N-(3-{1-[4-(3,4-dichlorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)c(Cl)c3)cc2)CC1
Show InChI InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33)
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8.20n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219038
PNG
(CHEMBL243507 | N-(3-{4-[3-(isobutylrylamino)phenyl...)
Show SMILES CCCCCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C37H49N3O2/c1-4-5-12-23-37(32-16-8-6-9-17-32,33-18-10-7-11-19-33)36(42)38-24-14-25-40-26-21-30(22-27-40)31-15-13-20-34(28-31)39-35(41)29(2)3/h6-11,13,15-20,28-30H,4-5,12,14,21-27H2,1-3H3,(H,38,42)(H,39,41)
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8.5n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219043
PNG
((2S)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m0/s1
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10n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219054
PNG
(2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]p...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1
Show InChI InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-8-6-7-24(19-25)23-15-17-30(18-16-23)20-22-11-13-27(14-12-22)32-26-9-4-3-5-10-26/h3-14,19,21,23H,15-18,20H2,1-2H3,(H,29,31)
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10n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219041
PNG
(CHEMBL242901 | N-{3-[4-(3-isobutyrylamino-phenyl)-...)
Show SMILES CCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C34H43N3O2/c1-4-34(29-14-7-5-8-15-29,30-16-9-6-10-17-30)33(39)35-21-12-22-37-23-19-27(20-24-37)28-13-11-18-31(25-28)36-32(38)26(2)3/h5-11,13-18,25-27H,4,12,19-24H2,1-3H3,(H,35,39)(H,36,38)
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14n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219055
PNG
(CHEMBL244791 | N-(3-{1-[3-(3,4-dichlorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)c(Cl)c3)c2)CC1
Show InChI InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-7-4-6-22(16-23)21-11-13-32(14-12-21)18-20-5-3-8-24(15-20)34-25-9-10-26(29)27(30)17-25/h3-10,15-17,19,21H,11-14,18H2,1-2H3,(H,31,33)
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18n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219066
PNG
(CHEMBL244578 | N-(3-{1-[3-(4-chlorophenoxy)benzyl]...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1
Show InChI InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-7-4-6-23(18-25)22-13-15-31(16-14-22)19-21-5-3-8-27(17-21)33-26-11-9-24(29)10-12-26/h3-12,17-18,20,22H,13-16,19H2,1-2H3,(H,30,32)
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23n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219045
PNG
(CHEMBL242003 | N-(5-{1-[4-(3,4-difluorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cc(ccc1C)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
Show InChI InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-28-16-23(7-4-20(28)3)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-26(30)27(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34)
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27n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219039
PNG
((2R)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m1/s1
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28n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219063
PNG
(2-methyl-N-{3-[1-(3-phenoxybenzyl)-4-piperidinyl]p...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccccc3)c2)CC1
Show InChI InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-10-7-9-24(19-25)23-14-16-30(17-15-23)20-22-8-6-13-27(18-22)32-26-11-4-3-5-12-26/h3-13,18-19,21,23H,14-17,20H2,1-2H3,(H,29,31)
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28n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219034
PNG
(CHEMBL243129 | N-{3-[1-(6-diphenylacetylamino-hexy...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C35H45N3O2/c1-27(2)34(39)37-32-19-13-18-31(26-32)28-20-24-38(25-21-28)23-12-4-3-11-22-36-35(40)33(29-14-7-5-8-15-29)30-16-9-6-10-17-30/h5-10,13-19,26-28,33H,3-4,11-12,20-25H2,1-2H3,(H,36,40)(H,37,39)
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29n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219065
PNG
(2-methyl-N-(3-{1-[3-(4-methylphenoxy)benzyl]-4-pip...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(C)cc3)c2)CC1
Show InChI InChI=1S/C29H34N2O2/c1-21(2)29(32)30-26-8-5-7-25(19-26)24-14-16-31(17-15-24)20-23-6-4-9-28(18-23)33-27-12-10-22(3)11-13-27/h4-13,18-19,21,24H,14-17,20H2,1-3H3,(H,30,32)
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31n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219024
PNG
(2-methyl-N-{4-methyl-3-[1-(3-{[(2R)-2-phenylpropan...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccccc2)CC1
Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m0/s1
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34n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219051
PNG
(CHEMBL245229 | N-(3-{1-[4-(4-methoxyphenoxy)benzyl...)
Show SMILES COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1
Show InChI InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32)
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35n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219028
PNG
(2-methyl-N-{4-methyl-3-[1-(3-{[(2S)-2-phenylpropan...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccccc2)CC1
Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m1/s1
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37n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50152456
PNG
((S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]...)
Show SMILES COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC |t:3|
Show InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1
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40n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]HEAT from human recombinant adrenergic alpha1A receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219059
PNG
(CHEMBL390212 | N-(3-{1-[3-(4-methoxyphenoxy)benzyl...)
Show SMILES COc1ccc(Oc2cccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)c2)cc1
Show InChI InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-8-5-7-24(19-25)23-14-16-31(17-15-23)20-22-6-4-9-28(18-22)34-27-12-10-26(33-3)11-13-27/h4-13,18-19,21,23H,14-17,20H2,1-3H3,(H,30,32)
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43n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219033
PNG
(CHEMBL243354 | N-{3-[1-(5-diphenylacetylamino-pent...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C34H43N3O2/c1-26(2)33(38)36-31-18-12-17-30(25-31)27-19-23-37(24-20-27)22-11-5-10-21-35-34(39)32(28-13-6-3-7-14-28)29-15-8-4-9-16-29/h3-4,6-9,12-18,25-27,32H,5,10-11,19-24H2,1-2H3,(H,35,39)(H,36,38)
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47n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219030
PNG
(CHEMBL243139 | N-{3-[1-(5-diphenylacetylamino-pent...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1
Show InChI InChI=1S/C33H41N3O2/c1-25(2)32(37)35-30-17-11-16-29(24-30)26-18-22-36(23-19-26)21-10-9-20-34-33(38)31(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-8,11-17,24-26,31H,9-10,18-23H2,1-2H3,(H,34,38)(H,35,37)
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50n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells


J Med Chem 50: 3870-82 (2007)


Article DOI: 10.1021/jm060381c
BindingDB Entry DOI: 10.7270/Q2930SWM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219052
PNG
(2-methyl-N-[3-(1-{3-[3-(trifluoromethyl)phenoxy]be...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cccc(c3)C(F)(F)F)c2)CC1
Show InChI InChI=1S/C29H31F3N2O2/c1-20(2)28(35)33-25-9-4-7-23(17-25)22-12-14-34(15-13-22)19-21-6-3-10-26(16-21)36-27-11-5-8-24(18-27)29(30,31)32/h3-11,16-18,20,22H,12-15,19H2,1-2H3,(H,33,35)
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65n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219061
PNG
(CHEMBL243794 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1
Show InChI InChI=1S/C23H27ClN2O2/c1-17(27)25-22-5-2-4-20(16-22)18-11-14-26(15-12-18)13-3-6-23(28)19-7-9-21(24)10-8-19/h2,4-5,7-10,16,18H,3,6,11-15H2,1H3,(H,25,27)
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70n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219048
PNG
(CHEMBL244372 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C29H31ClN2O2/c30-26-13-11-24(12-14-26)28(33)10-5-17-32-18-15-23(16-19-32)25-8-4-9-27(21-25)31-29(34)20-22-6-2-1-3-7-22/h1-4,6-9,11-14,21,23H,5,10,15-20H2,(H,31,34)
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84n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219058
PNG
(CHEMBL244004 | N-(3-{1-[4-(3,4-dimethylphenyl)-4-o...)
Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1
Show InChI InChI=1S/C25H32N2O2/c1-18-9-10-23(16-19(18)2)25(29)8-5-13-27-14-11-21(12-15-27)22-6-4-7-24(17-22)26-20(3)28/h4,6-7,9-10,16-17,21H,5,8,11-15H2,1-3H3,(H,26,28)
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100n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50219064
PNG
(CHEMBL245010 | N-(3-{1-[4-(4-chlorophenoxy)benzyl]...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)CC1
Show InChI InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-5-3-4-23(18-25)22-14-16-31(17-15-22)19-21-6-10-26(11-7-21)33-27-12-8-24(29)9-13-27/h3-13,18,20,22H,14-17,19H2,1-2H3,(H,30,32)
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110n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human recombinant dopamine D2 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50219054
PNG
(2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]p...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1
Show InChI InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-8-6-7-24(19-25)23-15-17-30(18-16-23)20-22-11-13-27(14-12-22)32-26-9-4-3-5-10-26/h3-14,19,21,23H,15-18,20H2,1-2H3,(H,29,31)
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120n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human recombinant dopamine D2 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219068
PNG
(CHEMBL245008 | N-(3-{1-[3-(3,5-dichlorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cc(Cl)cc(Cl)c3)c2)CC1
Show InChI InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-25-7-4-6-22(14-25)21-9-11-32(12-10-21)18-20-5-3-8-26(13-20)34-27-16-23(29)15-24(30)17-27/h3-8,13-17,19,21H,9-12,18H2,1-2H3,(H,31,33)
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140n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50219049
PNG
(1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydro...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23Cl2NO2/c22-18-7-3-16(4-8-18)20(25)2-1-13-24-14-11-21(26,12-15-24)17-5-9-19(23)10-6-17/h3-10,26H,1-2,11-15H2
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150n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]HEAT from human recombinant adrenergic alpha1A receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50219053
PNG
(CHEMBL242004 | N-(3-{1-4-(3,4-difluorophenoxy)benz...)
Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
Show InChI InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-23-7-4-20(3)26(16-23)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-27(30)28(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34)
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180n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]HEAT from human recombinant adrenergic alpha1A receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50219049
PNG
(1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydro...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23Cl2NO2/c22-18-7-3-16(4-8-18)20(25)2-1-13-24-14-11-21(26,12-15-24)17-5-9-19(23)10-6-17/h3-10,26H,1-2,11-15H2
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190n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human recombinant dopamine D2 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219056
PNG
(CHEMBL244163 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)C2CCCCC2)c1
Show InChI InChI=1S/C28H35ClN2O2/c29-25-13-11-22(12-14-25)27(32)10-5-17-31-18-15-21(16-19-31)24-8-4-9-26(20-24)30-28(33)23-6-2-1-3-7-23/h4,8-9,11-14,20-21,23H,1-3,5-7,10,15-19H2,(H,30,33)
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200n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Homo sapiens (Human))
BDBM50219047
PNG
(CHEMBL245231 | N-(3-(1-(4-(3,4-difluorophenoxy)ben...)
Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
Show InChI InChI=1S/C28H30F2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33)
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200n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]HEAT from human recombinant adrenergic alpha1A receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
GPR24


(RAT)
BDBM50219049
PNG
(1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydro...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23Cl2NO2/c22-18-7-3-16(4-8-18)20(25)2-1-13-24-14-11-21(26,12-15-24)17-5-9-19(23)10-6-17/h3-10,26H,1-2,11-15H2
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350n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
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