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Compile Data Set for Download or QSAR

Found 101 hits with Last Name = 'hofmann' and Initial = 't'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pepsin A


(Porcine)
BDBM50017789
PNG
((3S,4S)-3-Hydroxy-6-methyl-4-{3-methyl-2-[3-methyl...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C25H47N3O6/c1-10-34-21(31)13-19(29)18(11-14(2)3)26-24(32)23(17(8)9)28-25(33)22(16(6)7)27-20(30)12-15(4)5/h14-19,22-23,29H,10-13H2,1-9H3,(H,26,32)(H,27,30)(H,28,33)/t18-,19-,22-,23-/m0/s1
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10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of porcine pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Rhizopuspepsin


(Rhizopus microsporus var. chinensis)
BDBM50022290
PNG
(2-(3-Hydroxy-6-methyl-4-{3-methyl-2-[3-methyl-2-(3...)
Show SMILES COC(=O)C(Cc1ccccc1)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C33H54N4O7/c1-19(2)15-24(26(38)18-28(40)34-25(33(43)44-9)17-23-13-11-10-12-14-23)35-31(41)30(22(7)8)37-32(42)29(21(5)6)36-27(39)16-20(3)4/h10-14,19-22,24-26,29-30,38H,15-18H2,1-9H3,(H,34,40)(H,35,41)(H,36,39)(H,37,42)/t24-,25?,26-,29-,30-/m0/s1
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11n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of R. chinensis pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Rhizopuspepsin


(Rhizopus microsporus var. chinensis)
BDBM50022287
PNG
(8-Acetylamino-3-hydroxy-4-{3-methyl-2-[3-methyl-2-...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C27H50N4O7/c1-9-38-23(35)15-21(33)20(12-10-11-13-28-19(8)32)29-26(36)25(18(6)7)31-27(37)24(17(4)5)30-22(34)14-16(2)3/h16-18,20-21,24-25,33H,9-15H2,1-8H3,(H,28,32)(H,29,36)(H,30,34)(H,31,37)/t20-,21-,24?,25+/m0/s1
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29n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of R. chinensis pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Rhizopuspepsin


(Rhizopus microsporus var. chinensis)
BDBM50022285
PNG
((3S,4S) Acetate7-ethoxycarbonyl-6-hydroxy-5-{3-met...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CCCC[NH3+])NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C25H48N4O6/c1-8-35-21(32)14-19(30)18(11-9-10-12-26)27-24(33)23(17(6)7)29-25(34)22(16(4)5)28-20(31)13-15(2)3/h15-19,22-23,30H,8-14,26H2,1-7H3,(H,27,33)(H,28,31)(H,29,34)/p+1/t18-,19-,22?,23+/m0/s1
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33n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of R. chinensis pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Rhizopuspepsin


(Rhizopus microsporus var. chinensis)
BDBM50017789
PNG
((3S,4S)-3-Hydroxy-6-methyl-4-{3-methyl-2-[3-methyl...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C25H47N3O6/c1-10-34-21(31)13-19(29)18(11-14(2)3)26-24(32)23(17(8)9)28-25(33)22(16(6)7)27-20(30)12-15(4)5/h14-19,22-23,29H,10-13H2,1-9H3,(H,26,32)(H,27,30)(H,28,33)/t18-,19-,22-,23-/m0/s1
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42n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of R. chinensis pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Rhizopuspepsin


(Rhizopus microsporus var. chinensis)
BDBM50022289
PNG
(Acetate6-ethoxycarbonyl-5-hydroxy-4-{3-methyl-2-[3...)
Show SMILES CCOC(=O)CC(O)[C@H](CCC[NH3+])NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C24H46N4O6/c1-8-34-20(31)13-18(29)17(10-9-11-25)26-23(32)22(16(6)7)28-24(33)21(15(4)5)27-19(30)12-14(2)3/h14-18,21-22,29H,8-13,25H2,1-7H3,(H,26,32)(H,27,30)(H,28,33)/p+1/t17-,18?,21?,22+/m0/s1
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47n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of R. chinensis pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Pepsin A


(Porcine)
BDBM50022285
PNG
((3S,4S) Acetate7-ethoxycarbonyl-6-hydroxy-5-{3-met...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CCCC[NH3+])NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C25H48N4O6/c1-8-35-21(32)14-19(30)18(11-9-10-12-26)27-24(33)23(17(6)7)29-25(34)22(16(4)5)28-20(31)13-15(2)3/h15-19,22-23,30H,8-14,26H2,1-7H3,(H,27,33)(H,28,31)(H,29,34)/p+1/t18-,19-,22?,23+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of porcine pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Pepsin A


(Porcine)
BDBM50022289
PNG
(Acetate6-ethoxycarbonyl-5-hydroxy-4-{3-methyl-2-[3...)
Show SMILES CCOC(=O)CC(O)[C@H](CCC[NH3+])NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C24H46N4O6/c1-8-34-20(31)13-18(29)17(10-9-11-25)26-23(32)22(16(6)7)28-24(33)21(15(4)5)27-19(30)12-14(2)3/h14-18,21-22,29H,8-13,25H2,1-7H3,(H,26,32)(H,27,30)(H,28,33)/p+1/t17-,18?,21?,22+/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of porcine pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Pepsin A


(Porcine)
BDBM50022287
PNG
(8-Acetylamino-3-hydroxy-4-{3-methyl-2-[3-methyl-2-...)
Show SMILES CCOC(=O)C[C@H](O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C27H50N4O7/c1-9-38-23(35)15-21(33)20(12-10-11-13-28-19(8)32)29-26(36)25(18(6)7)31-27(37)24(17(4)5)30-22(34)14-16(2)3/h16-18,20-21,24-25,33H,9-15H2,1-8H3,(H,28,32)(H,29,36)(H,30,34)(H,31,37)/t20-,21-,24?,25+/m0/s1
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1.90E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of porcine pepsin


J Med Chem 30: 286-95 (1987)


BindingDB Entry DOI: 10.7270/Q2QF8RVZ
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 2n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 5.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of MEK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 57n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 autophosphorylation by cell based assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 150n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of MNK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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n/an/a 170n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 190n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 303n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of cKIT by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 5


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 640n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of MK5 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 673n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of cKIT by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 763n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ALK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 763n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ALK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 1


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 950n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ERK2 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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n/an/a 3.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ALK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 4.10E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of TYK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 4.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of TYK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 4.70E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LCK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a 6.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LCK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 1


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 6.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ERK2 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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n/an/a 6.84E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of MEK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 7.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RET by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4 (EphB4)


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 7.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of EPHB4 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a 7.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of cKIT by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of LCK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of TYK2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of p38alpha by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 2


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of CDK2A by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Insulin receptor


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of INSR by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ALK by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of HER2 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
cAMP-dependent protein kinase (PKA)


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of PKAalpha by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of GSK3-beta by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1)


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of PDK1 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50413752
PNG
(CHEMBL2012519 | L-783277)
Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(O)CCC[C@H](C)OC2=O)c1 |r|
Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,14,20,22H,3-8H2,1-2H3/t11-,14?/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of FGFR3 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 1


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ERK2 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4 (EphB4)


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of EPHB4 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret


(Homo sapiens (Human))
BDBM50335374
PNG
((3S,9S)-9,16-dihydroxy-14-methoxy-3-methyl-3,4,9,1...)
Show SMILES COc1cc(O)c2c(CCC[C@H](O)CC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:17.17|
Show InChI InChI=1S/C19H24O6/c1-12-5-3-7-14(20)10-15(21)8-4-6-13-9-16(24-2)11-17(22)18(13)19(23)25-12/h3,7,9,11-12,15,21-22H,4-6,8,10H2,1-2H3/t12-,15-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of RET by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 1


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of ERK2 by Caliper mobility shift assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4 (EphB4)


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of EPHB4 by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))
BDBM50335376
PNG
((S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-...)
Show SMILES COc1cc(O)c2c(CCCCCC(=O)C=CC[C@H](C)OC2=O)c1 |r,w:16.16|
Show InChI InChI=1S/C19H24O5/c1-13-7-6-10-15(20)9-5-3-4-8-14-11-16(23-2)12-17(21)18(14)19(22)24-13/h6,10-13,21H,3-5,7-9H2,1-2H3/t13-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Inhibition of cKIT by TR-FRET based LanthaScreen assay


ACS Med Chem Lett 2: 22-27 (2011)


Article DOI: 10.1021/ml1001807
BindingDB Entry DOI: 10.7270/Q2542NWT
More data for this
Ligand-Target Pair
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