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Compile Data Set for Download or QSAR

Found 411 hits with Last Name = 'ichimura' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290167
PNG
(1,3-Diethyl-8-[(E)-2-(4-methoxy-2,3-dimethyl-pheny...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-7-24-19-18(20(26)25(8-2)21(24)27)23(5)17(22-19)12-10-15-9-11-16(28-6)14(4)13(15)3/h9-12H,7-8H2,1-6H3/b12-10+
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0.670n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290165
PNG
(8-[(E)-2-(2,4-Dimethoxy-3-methyl-phenyl)-vinyl]-1,...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O4/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(4)16(22-19)12-10-14-9-11-15(28-5)13(3)18(14)29-6/h9-12H,7-8H2,1-6H3/b12-10+
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0.670n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50006710
PNG
(8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50290165
PNG
(8-[(E)-2-(2,4-Dimethoxy-3-methyl-phenyl)-vinyl]-1,...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O4/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(4)16(22-19)12-10-14-9-11-15(28-5)13(3)18(14)29-6/h9-12H,7-8H2,1-6H3/b12-10+
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1.60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50006714
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(3,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-19(22(28)27(12-8-2)23(26)29)25(3)18(24-21)10-9-15-13-16(30-4)20(32-6)17(14-15)31-5/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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1.70n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50290167
PNG
(1,3-Diethyl-8-[(E)-2-(4-methoxy-2,3-dimethyl-pheny...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-7-24-19-18(20(26)25(8-2)21(24)27)23(5)17(22-19)12-10-15-9-11-16(28-6)14(4)13(15)3/h9-12H,7-8H2,1-6H3/b12-10+
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2n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50176050
PNG
(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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2.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290168
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(2,3,4-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-16(20(26)25(8-2)21(24)27)23(3)15(22-19)12-10-13-9-11-14(28-4)18(30-6)17(13)29-5/h9-12H,7-8H2,1-6H3/b12-10+
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2.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50047184
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(3,4,5-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(3)16(22-19)10-9-13-11-14(28-4)18(30-6)15(12-13)29-5/h9-12H,7-8H2,1-6H3/b10-9+
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2.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50290168
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(2,3,4-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-16(20(26)25(8-2)21(24)27)23(3)15(22-19)12-10-13-9-11-14(28-4)18(30-6)17(13)29-5/h9-12H,7-8H2,1-6H3/b12-10+
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3.90n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290169
PNG
(8-[(E)-2-(4-Methoxy-2,3-dimethyl-phenyl)-vinyl]-7-...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O3/c1-7-13-26-21-20(22(28)27(14-8-2)23(26)29)25(5)19(24-21)12-10-17-9-11-18(30-6)16(4)15(17)3/h9-12H,7-8,13-14H2,1-6H3/b12-10+
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3.90n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50006703
PNG
(8-[(E)-2-(4-Methoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-5-13-24-19-18(20(26)25(14-6-2)21(24)27)23(3)17(22-19)12-9-15-7-10-16(28-4)11-8-15/h7-12H,5-6,13-14H2,1-4H3/b12-9+
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4.5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50006702
PNG
(7-Methyl-1,3-dipropyl-8-((E)-styryl)-3,7-dihydro-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccccc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H24N4O2/c1-4-13-23-18-17(19(25)24(14-5-2)20(23)26)22(3)16(21-18)12-11-15-9-7-6-8-10-15/h6-12H,4-5,13-14H2,1-3H3/b12-11+
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4.90n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50047184
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(3,4,5-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(3)16(22-19)10-9-13-11-14(28-4)18(30-6)15(12-13)29-5/h9-12H,7-8H2,1-6H3/b10-9+
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6.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50047197
PNG
(8-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)cc(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-10-25-20-19(21(27)26(11-7-2)22(25)28)24(3)18(23-20)9-8-15-12-16(29-4)14-17(13-15)30-5/h8-9,12-14H,6-7,10-11H2,1-5H3/b9-8+
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6.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50047171
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(2,3,4-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-13-26-21-18(22(28)27(14-8-2)23(26)29)25(3)17(24-21)12-10-15-9-11-16(30-4)20(32-6)19(15)31-5/h9-12H,7-8,13-14H2,1-6H3/b12-10+
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6.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290170
PNG
(8-[(E)-2-(2,4-Dimethoxy-3-methyl-phenyl)-vinyl]-7-...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(C)c3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O4/c1-7-13-26-21-19(22(28)27(14-8-2)23(26)29)25(4)18(24-21)12-10-16-9-11-17(30-5)15(3)20(16)31-6/h9-12H,7-8,13-14H2,1-6H3/b12-10+
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7.40n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50006710
PNG
(8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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7.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290166
PNG
(8-[(E)-2-(2,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)14-17(15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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8.20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50176050
PNG
(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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13n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50006714
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(3,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-19(22(28)27(12-8-2)23(26)29)25(3)18(24-21)10-9-15-13-16(30-4)20(32-6)17(14-15)31-5/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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14n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50006702
PNG
(7-Methyl-1,3-dipropyl-8-((E)-styryl)-3,7-dihydro-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccccc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H24N4O2/c1-4-13-23-18-17(19(25)24(14-5-2)20(23)26)22(3)16(21-18)12-11-15-9-7-6-8-10-15/h6-12H,4-5,13-14H2,1-3H3/b12-11+
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15n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50006703
PNG
(8-[(E)-2-(4-Methoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-5-13-24-19-18(20(26)25(14-6-2)21(24)27)23(3)17(22-19)12-9-15-7-10-16(28-4)11-8-15/h7-12H,5-6,13-14H2,1-4H3/b12-9+
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18n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A2a and A3


(Rattus norvegicus (rat))
BDBM50006707
PNG
(8-[(E)-2-(4-Chloro-phenyl)-vinyl]-7-methyl-1,3-dip...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(Cl)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H23ClN4O2/c1-4-12-24-18-17(19(26)25(13-5-2)20(24)27)23(3)16(22-18)11-8-14-6-9-15(21)10-7-14/h6-11H,4-5,12-13H2,1-3H3/b11-8+
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35n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50290168
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(2,3,4-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-16(20(26)25(8-2)21(24)27)23(3)15(22-19)12-10-13-9-11-14(28-4)18(30-6)17(13)29-5/h9-12H,7-8H2,1-6H3/b12-10+
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37n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50006707
PNG
(8-[(E)-2-(4-Chloro-phenyl)-vinyl]-7-methyl-1,3-dip...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(Cl)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H23ClN4O2/c1-4-12-24-18-17(19(26)25(13-5-2)20(24)27)23(3)16(22-18)11-8-14-6-9-15(21)10-7-14/h6-11H,4-5,12-13H2,1-3H3/b11-8+
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49n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50290172
PNG
(8-[(E)-2-(2,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)cc3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)12-15(13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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57n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290168
PNG
(1,3-Diethyl-7-methyl-8-[(E)-2-(2,3,4-trimethoxy-ph...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O5/c1-7-24-19-16(20(26)25(8-2)21(24)27)23(3)15(22-19)12-10-13-9-11-14(28-4)18(30-6)17(13)29-5/h9-12H,7-8H2,1-6H3/b12-10+
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61n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50006710
PNG
(8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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62n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50006703
PNG
(8-[(E)-2-(4-Methoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-5-13-24-19-18(20(26)25(14-6-2)21(24)27)23(3)17(22-19)12-9-15-7-10-16(28-4)11-8-15/h7-12H,5-6,13-14H2,1-4H3/b12-9+
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63n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290167
PNG
(1,3-Diethyl-8-[(E)-2-(4-methoxy-2,3-dimethyl-pheny...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-7-24-19-18(20(26)25(8-2)21(24)27)23(5)17(22-19)12-10-15-9-11-16(28-6)14(4)13(15)3/h9-12H,7-8H2,1-6H3/b12-10+
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78n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290165
PNG
(8-[(E)-2-(2,4-Dimethoxy-3-methyl-phenyl)-vinyl]-1,...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O4/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(4)16(22-19)12-10-14-9-11-15(28-5)13(3)18(14)29-6/h9-12H,7-8H2,1-6H3/b12-10+
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83n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50006702
PNG
(7-Methyl-1,3-dipropyl-8-((E)-styryl)-3,7-dihydro-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccccc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H24N4O2/c1-4-13-23-18-17(19(25)24(14-5-2)20(23)26)22(3)16(21-18)12-11-15-9-7-6-8-10-15/h6-12H,4-5,13-14H2,1-3H3/b12-11+
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100n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50290165
PNG
(8-[(E)-2-(2,4-Dimethoxy-3-methyl-phenyl)-vinyl]-1,...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O4/c1-7-24-19-17(20(26)25(8-2)21(24)27)23(4)16(22-19)12-10-14-9-11-15(28-5)13(3)18(14)29-6/h9-12H,7-8H2,1-6H3/b12-10+
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110n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50290167
PNG
(1,3-Diethyl-8-[(E)-2-(4-methoxy-2,3-dimethyl-pheny...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-7-24-19-18(20(26)25(8-2)21(24)27)23(5)17(22-19)12-10-15-9-11-16(28-6)14(4)13(15)3/h9-12H,7-8H2,1-6H3/b12-10+
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120n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50006714
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(3,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-19(22(28)27(12-8-2)23(26)29)25(3)18(24-21)10-9-15-13-16(30-4)20(32-6)17(14-15)31-5/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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120n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50176050
PNG
(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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150n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290166
PNG
(8-[(E)-2-(2,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)14-17(15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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150n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50047171
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(2,3,4-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-13-26-21-18(22(28)27(14-8-2)23(26)29)25(3)17(24-21)12-10-15-9-11-16(30-4)20(32-6)19(15)31-5/h9-12H,7-8,13-14H2,1-6H3/b12-10+
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160n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine Receptors A2a (A2a)


(Rattus norvegicus (rat))
BDBM50047174
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(2,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)cc3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-20(22(28)27(12-8-2)23(26)29)25(3)19(24-21)10-9-15-13-17(31-5)18(32-6)14-16(15)30-4/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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170n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50006702
PNG
(7-Methyl-1,3-dipropyl-8-((E)-styryl)-3,7-dihydro-p...)
Show SMILES CCCn1c2nc(\C=C\c3ccccc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H24N4O2/c1-4-13-23-18-17(19(25)24(14-5-2)20(23)26)22(3)16(21-18)12-11-15-9-7-6-8-10-15/h6-12H,4-5,13-14H2,1-3H3/b12-11+
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220n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50006703
PNG
(8-[(E)-2-(4-Methoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C21H26N4O3/c1-5-13-24-19-18(20(26)25(14-6-2)21(24)27)23(3)17(22-19)12-9-15-7-10-16(28-4)11-8-15/h7-12H,5-6,13-14H2,1-4H3/b12-9+
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340n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]-NECA (+CPA) displacement.


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50006710
PNG
(8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C22H28N4O4/c1-6-12-25-20-19(21(27)26(13-7-2)22(25)28)24(3)18(23-20)11-9-15-8-10-16(29-4)17(14-15)30-5/h8-11,14H,6-7,12-13H2,1-5H3/b11-9+
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390n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50006707
PNG
(8-[(E)-2-(4-Chloro-phenyl)-vinyl]-7-methyl-1,3-dip...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(Cl)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H23ClN4O2/c1-4-12-24-18-17(19(26)25(13-5-2)20(24)27)23(3)16(22-18)11-8-14-6-9-15(21)10-7-14/h6-11H,4-5,12-13H2,1-3H3/b11-8+
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470n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes (shielded from light)


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290169
PNG
(8-[(E)-2-(4-Methoxy-2,3-dimethyl-phenyl)-vinyl]-7-...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(OC)c(C)c3C)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O3/c1-7-13-26-21-20(22(28)27(14-8-2)23(26)29)25(5)19(24-21)12-10-17-9-11-18(30-6)16(4)15(17)3/h9-12H,7-8,13-14H2,1-6H3/b12-10+
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560n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50176050
PNG
(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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580n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor


(Rattus norvegicus (rat))
BDBM50006714
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(3,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-19(22(28)27(12-8-2)23(26)29)25(3)18(24-21)10-9-15-13-16(30-4)20(32-6)17(14-15)31-5/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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1.10E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50290172
PNG
(8-[(E)-2-(2,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl...)
Show SMILES CCn1c2nc(\C=C\c3ccc(OC)cc3OC)n(C)c2c(=O)n(CC)c1=O
Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)12-15(13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
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2.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of rat forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine A1 receptor


(GUINEA PIG)
BDBM50047174
PNG
(7-Methyl-1,3-dipropyl-8-[(E)-2-(2,4,5-trimethoxy-p...)
Show SMILES CCCn1c2nc(\C=C\c3cc(OC)c(OC)cc3OC)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C23H30N4O5/c1-7-11-26-21-20(22(28)27(12-8-2)23(26)29)25(3)19(24-21)10-9-15-13-17(31-5)18(32-6)14-16(15)30-4/h9-10,13-14H,7-8,11-12H2,1-6H3/b10-9+
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3.30E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of guinea pig forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
Adenosine A1 receptor


(GUINEA PIG)
BDBM50006707
PNG
(8-[(E)-2-(4-Chloro-phenyl)-vinyl]-7-methyl-1,3-dip...)
Show SMILES CCCn1c2nc(\C=C\c3ccc(Cl)cc3)n(C)c2c(=O)n(CCC)c1=O
Show InChI InChI=1S/C20H23ClN4O2/c1-4-12-24-18-17(19(26)25(13-5-2)20(24)27)23(3)16(22-18)11-8-14-6-9-15(21)10-7-14/h6-11H,4-5,12-13H2,1-3H3/b11-8+
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>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-CHA from Adenosine A1 receptor of guinea pig forebrain membranes


Bioorg Med Chem Lett 7: 2349-2352 (1997)


Article DOI: 10.1016/S0960-894X(97)00440-X
BindingDB Entry DOI: 10.7270/Q2PV6KB7
More data for this
Ligand-Target Pair
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