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Compile Data Set for Download or QSAR

Found 2509 hits with Last Name = 'kort' and Initial = 'me'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124595
PNG
(5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4ccc(O)c(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H22ClNO2/c1-5-6-16-19-13(20-17(26-16)10-9-15(25)21(20)23)7-8-14-18(19)12(2)11-22(3,4)24-14/h5,7-11,16,24-25H,1,6H2,2-4H3
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0.580n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124619
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES COc1c(O)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H25NO3/c1-6-7-17-20-14(21-18(27-17)11-10-16(25)22(21)26-5)8-9-15-19(20)13(2)12-23(3,4)24-15/h6,8-12,17,24-25H,1,7H2,2-5H3
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0.950n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124603
PNG
(5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H22ClNO/c1-5-7-17-21-14(20-15(23)8-6-9-18(20)25-17)10-11-16-19(21)13(2)12-22(3,4)24-16/h5-6,8-12,17,24H,1,7H2,2-4H3
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1.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124621
PNG
(5-Allyl-10-methoxy-2,2,4,7-tetramethyl-2,5-dihydro...)
Show SMILES COc1ccc(C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C24H27NO2/c1-7-8-19-21-16(22-18(26-6)12-9-14(2)23(22)27-19)10-11-17-20(21)15(3)13-24(4,5)25-17/h7,9-13,19,25H,1,8H2,2-6H3
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2n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124597
PNG
(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(OC(F)F)c-34)c12 |t:1|
Show InChI InChI=1S/C23H23F2NO2/c1-5-7-16-21-14(10-11-15-19(21)13(2)12-23(3,4)26-15)20-17(27-16)8-6-9-18(20)28-22(24)25/h5-6,8-12,16,22,26H,1,7H2,2-4H3
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2.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124591
PNG
(5-Allyl-7-bromo-10-chloro-2,2,4-trimethyl-2,5-dihy...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4c(Br)cc(O)c(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H21BrClNO2/c1-5-6-16-18-12(19-20(24)15(26)9-13(23)21(19)27-16)7-8-14-17(18)11(2)10-22(3,4)25-14/h5,7-10,16,25-26H,1,6H2,2-4H3
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2.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124594
PNG
((5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(CO)c-34)c12 |t:1|
Show InChI InChI=1S/C23H25NO2/c1-5-7-18-22-16(21-15(13-25)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)24-17/h5-6,8-12,18,24-25H,1,7,13H2,2-4H3
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2.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM19190
PNG
((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23|
Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
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2.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50107347
PNG
((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...)
Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:21|
Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3
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2.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124614
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES COC(=O)c1ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1OC |t:22|
Show InChI InChI=1S/C25H27NO4/c1-7-8-18-21-15(9-11-17-20(21)14(2)13-25(3,4)26-17)22-19(30-18)12-10-16(23(22)28-5)24(27)29-6/h7,9-13,18,26H,1,8H2,2-6H3
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2.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124604
PNG
(5-Allyl-9-fluoro-10-methoxy-2,2,4-trimethyl-2,5-di...)
Show SMILES COc1c(F)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24FNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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3.80n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124605
PNG
(5-Allyl-7-bromo-10-methoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES COc1ccc(Br)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24BrNO2/c1-6-7-18-20-14(21-17(26-5)11-9-15(24)22(21)27-18)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,18,25H,1,7H2,2-5H3
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4.10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124609
PNG
(5-Allyl-2,2,4-trimethyl-10-prop-2-ynyloxy-2,5-dihy...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(OCC#C)c-34)c12 |t:1|
Show InChI InChI=1S/C25H25NO2/c1-6-9-20-24-17(12-13-18-22(24)16(3)15-25(4,5)26-18)23-19(27-14-7-2)10-8-11-21(23)28-20/h2,6,8,10-13,15,20,26H,1,9,14H2,3-5H3
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4.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124606
PNG
(5-Allyl-2,2,4-trimethyl-10-vinyl-2,5-dihydro-1H-6-...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C=C)c-34)c12 |t:1|
Show InChI InChI=1S/C24H25NO/c1-6-9-19-23-17(22-16(7-2)10-8-11-20(22)26-19)12-13-18-21(23)15(3)14-24(4,5)25-18/h6-8,10-14,19,25H,1-2,9H2,3-5H3
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4.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124593
PNG
(5-Allyl-2,2,4-trimethyl-10-methylsulfanyl-2,5-dihy...)
Show SMILES CSc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:21|
Show InChI InChI=1S/C23H25NOS/c1-6-8-17-22-15(21-18(25-17)9-7-10-19(21)26-5)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,17,24H,1,8H2,2-5H3
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5.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124620
PNG
(5-Allyl-9-bromo-10-methoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES COc1c(Br)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24BrNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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5.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124612
PNG
(5-Allyl-9-chloro-10-methoxy-2,2,4-trimethyl-2,5-di...)
Show SMILES COc1c(Cl)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24ClNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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5.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124608
PNG
((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1c(CO)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C24H27NO3/c1-6-7-18-21-16(9-10-17-20(21)14(2)12-24(3,4)25-17)22-19(28-18)11-8-15(13-26)23(22)27-5/h6,8-12,18,25-26H,1,7,13H2,2-5H3
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6.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124615
PNG
(5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#C)c-34)c12 |t:1|
Show InChI InChI=1S/C24H23NO/c1-6-9-19-23-17(22-16(7-2)10-8-11-20(22)26-19)12-13-18-21(23)15(3)14-24(4,5)25-18/h2,6,8,10-14,19,25H,1,9H2,3-5H3
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6.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124611
PNG
((5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CNc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:21|
Show InChI InChI=1S/C23H26N2O/c1-6-8-18-22-15(21-16(24-5)9-7-10-19(21)26-18)11-12-17-20(22)14(2)13-23(3,4)25-17/h6-7,9-13,18,24-25H,1,8H2,2-5H3
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7n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124595
PNG
(5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4ccc(O)c(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H22ClNO2/c1-5-6-16-19-13(20-17(26-16)10-9-15(25)21(20)23)7-8-14-18(19)12(2)11-22(3,4)24-14/h5,7-11,16,24-25H,1,6H2,2-4H3
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7.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124600
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#N)c-34)c12 |t:1|
Show InChI InChI=1S/C23H22N2O/c1-5-7-18-22-16(21-15(13-24)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)25-17/h5-6,8-12,18,25H,1,7H2,2-4H3
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9.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124613
PNG
(5-Allyl-9,10-dimethoxy-2,2,4-trimethyl-2,5-dihydro...)
Show SMILES COc1ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1OC |t:20|
Show InChI InChI=1S/C24H27NO3/c1-7-8-17-21-15(9-10-16-20(21)14(2)13-24(3,4)25-16)22-18(28-17)11-12-19(26-5)23(22)27-6/h7,9-13,17,25H,1,8H2,2-6H3
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12n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124607
PNG
(5-Allyl-9-allyloxy-10-methoxy-2,2,4-trimethyl-2,5-...)
Show SMILES COc1c(OCC=C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25|
Show InChI InChI=1S/C26H29NO3/c1-7-9-19-23-17(10-11-18-22(23)16(3)15-26(4,5)27-18)24-20(30-19)12-13-21(25(24)28-6)29-14-8-2/h7-8,10-13,15,19,27H,1-2,9,14H2,3-6H3
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12n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124599
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-9-prop-2-ynylox...)
Show SMILES COc1c(OCC#C)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25|
Show InChI InChI=1S/C26H27NO3/c1-7-9-19-23-17(10-11-18-22(23)16(3)15-26(4,5)27-18)24-20(30-19)12-13-21(25(24)28-6)29-14-8-2/h2,7,10-13,15,19,27H,1,9,14H2,3-6H3
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14n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124601
PNG
(5-Allyl-10-methoxymethyl-2,2,4-trimethyl-2,5-dihyd...)
Show SMILES COCc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C24H27NO2/c1-6-8-19-23-17(22-16(14-26-5)9-7-10-20(22)27-19)11-12-18-21(23)15(2)13-24(3,4)25-18/h6-7,9-13,19,25H,1,8,14H2,2-5H3
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18n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124591
PNG
(5-Allyl-7-bromo-10-chloro-2,2,4-trimethyl-2,5-dihy...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4c(Br)cc(O)c(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H21BrClNO2/c1-5-6-16-18-12(19-20(24)15(26)9-13(23)21(19)27-16)7-8-14-17(18)11(2)10-22(3,4)25-14/h5,7-10,16,25-26H,1,6H2,2-4H3
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22n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124596
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(O)c-34)c12 |t:1|
Show InChI InChI=1S/C22H23NO2/c1-5-7-17-21-14(20-16(24)8-6-9-18(20)25-17)10-11-15-19(21)13(2)12-22(3,4)23-15/h5-6,8-12,17,23-24H,1,7H2,2-4H3
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28n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124612
PNG
(5-Allyl-9-chloro-10-methoxy-2,2,4-trimethyl-2,5-di...)
Show SMILES COc1c(Cl)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24ClNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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29n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124616
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dih...)
Show SMILES COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C25H27NO2/c1-7-9-20-22-17(11-12-18-21(22)15(3)14-25(4,5)26-18)23-19(27-6)13-10-16(8-2)24(23)28-20/h7-8,10-14,20,26H,1-2,9H2,3-6H3
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34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124620
PNG
(5-Allyl-9-bromo-10-methoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES COc1c(Br)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24BrNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12 |t:1|
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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34n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072707
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(CC=C)c3c12 |t:1|
Show InChI InChI=1S/C22H23NO/c1-5-8-19-21-16(15-9-6-7-10-18(15)24-19)11-12-17-20(21)14(2)13-22(3,4)23-17/h5-7,9-13,19,23H,1,8H2,2-4H3
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36n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124602
PNG
((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1c(OCC#N)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:25|
Show InChI InChI=1S/C25H26N2O3/c1-6-7-18-22-16(8-9-17-21(22)15(2)14-25(3,4)27-17)23-19(30-18)10-11-20(24(23)28-5)29-13-12-26/h6,8-11,14,18,27H,1,7,13H2,2-5H3
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51n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124603
PNG
(5-Allyl-10-chloro-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(Cl)c-34)c12 |t:1|
Show InChI InChI=1S/C22H22ClNO/c1-5-7-17-21-14(20-15(23)8-6-9-18(20)25-17)10-11-16-19(21)13(2)12-22(3,4)24-16/h5-6,8-12,17,24H,1,7H2,2-4H3
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61n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124618
PNG
(5-Allyl-10-ethoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...)
Show SMILES CCOc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C24H27NO2/c1-6-9-19-23-16(22-18(26-7-2)10-8-11-20(22)27-19)12-13-17-21(23)15(3)14-24(4,5)25-17/h6,8,10-14,19,25H,1,7,9H2,2-5H3
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65n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124598
PNG
(5-Allyl-10-allyloxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(OCC=C)c-34)c12 |t:1|
Show InChI InChI=1S/C25H27NO2/c1-6-9-20-24-17(12-13-18-22(24)16(3)15-25(4,5)26-18)23-19(27-14-7-2)10-8-11-21(23)28-20/h6-8,10-13,15,20,26H,1-2,9,14H2,3-5H3
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88n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50124597
PNG
(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(OC(F)F)c-34)c12 |t:1|
Show InChI InChI=1S/C23H23F2NO2/c1-5-7-16-21-14(10-11-15-19(21)13(2)12-23(3,4)26-15)20-17(27-16)8-6-9-18(20)28-22(24)25/h5-6,8-12,16,22,26H,1,7H2,2-4H3
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96n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards testosterone receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124608
PNG
((5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H...)
Show SMILES COc1c(CO)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C24H27NO3/c1-6-7-18-21-16(9-10-17-20(21)14(2)12-24(3,4)25-17)22-19(28-18)11-8-15(13-26)23(22)27-5/h6,8-12,18,25-26H,1,7,13H2,2-5H3
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100n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124610
PNG
(C-(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(CN)c-34)c12 |t:1|
Show InChI InChI=1S/C23H26N2O/c1-5-7-18-22-16(21-15(13-24)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)25-17/h5-6,8-12,18,25H,1,7,13,24H2,2-4H3
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140n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124619
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES COc1c(O)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H25NO3/c1-6-7-17-20-14(21-18(27-17)11-10-16(25)22(21)26-5)8-9-15-19(20)13(2)12-23(3,4)24-15/h6,8-12,17,24-25H,1,7H2,2-5H3
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150n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124594
PNG
((5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(CO)c-34)c12 |t:1|
Show InChI InChI=1S/C23H25NO2/c1-5-7-18-22-16(21-15(13-25)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)24-17/h5-6,8-12,18,24-25H,1,7,13H2,2-4H3
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192n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124604
PNG
(5-Allyl-9-fluoro-10-methoxy-2,2,4-trimethyl-2,5-di...)
Show SMILES COc1c(F)ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:22|
Show InChI InChI=1S/C23H24FNO2/c1-6-7-17-20-14(21-18(27-17)11-9-15(24)22(21)26-5)8-10-16-19(20)13(2)12-23(3,4)25-16/h6,8-12,17,25H,1,7H2,2-5H3
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200n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124614
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-...)
Show SMILES COC(=O)c1ccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c2c1OC |t:22|
Show InChI InChI=1S/C25H27NO4/c1-7-8-18-21-15(9-11-17-20(21)14(2)13-25(3,4)26-17)22-19(30-18)12-10-16(23(22)28-5)24(27)29-6/h7,9-13,18,26H,1,8H2,2-6H3
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200n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Androgen Receptor


(Homo sapiens (Human))
BDBM50124606
PNG
(5-Allyl-2,2,4-trimethyl-10-vinyl-2,5-dihydro-1H-6-...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C=C)c-34)c12 |t:1|
Show InChI InChI=1S/C24H25NO/c1-6-9-19-23-17(22-16(7-2)10-8-11-20(22)26-19)12-13-18-21(23)15(3)14-24(4,5)25-18/h6-8,10-14,19,25H,1-2,9H2,3-5H3
PDB
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239n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards testosterone receptor


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124596
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(O)c-34)c12 |t:1|
Show InChI InChI=1S/C22H23NO2/c1-5-7-17-21-14(20-16(24)8-6-9-18(20)25-17)10-11-15-19(21)13(2)12-22(3,4)23-15/h5-6,8-12,17,23-24H,1,7H2,2-4H3
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330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124597
PNG
(5-Allyl-10-difluoromethoxy-2,2,4-trimethyl-2,5-dih...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(OC(F)F)c-34)c12 |t:1|
Show InChI InChI=1S/C23H23F2NO2/c1-5-7-16-21-14(10-11-15-19(21)13(2)12-23(3,4)26-15)20-17(27-16)8-6-9-18(20)28-22(24)25/h5-6,8-12,16,22,26H,1,7H2,2-4H3
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349n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50124592
PNG
(5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Show SMILES COC(=O)c1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C24H25NO3/c1-6-8-18-22-15(11-12-17-20(22)14(2)13-24(3,4)25-17)21-16(23(26)27-5)9-7-10-19(21)28-18/h6-7,9-13,18,25H,1,8H2,2-5H3
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400n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124606
PNG
(5-Allyl-2,2,4-trimethyl-10-vinyl-2,5-dihydro-1H-6-...)
Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C=C)c-34)c12 |t:1|
Show InChI InChI=1S/C24H25NO/c1-6-9-19-23-17(22-16(7-2)10-8-11-20(22)26-19)12-13-18-21(23)15(3)14-24(4,5)25-18/h6-8,10-14,19,25H,1-2,9H2,3-5H3
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435n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50124616
PNG
(5-Allyl-10-methoxy-2,2,4-trimethyl-7-vinyl-2,5-dih...)
Show SMILES COc1ccc(C=C)c2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:23|
Show InChI InChI=1S/C25H27NO2/c1-7-9-20-22-17(11-12-18-21(22)15(3)14-25(4,5)26-18)23-19(27-6)13-10-16(8-2)24(23)28-20/h7-8,10-14,20,26H,1-2,9H2,3-6H3
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450n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-progesterone from human Progesterone receptor A


J Med Chem 46: 1016-30 (2003)


Article DOI: 10.1021/jm020335m
BindingDB Entry DOI: 10.7270/Q2MP52NB
More data for this
Ligand-Target Pair
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