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Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'kulp' and Initial = 'sk'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM50353484
PNG
(CHEMBL1830587)
Show SMILES CNC(=O)CCc1cc(-c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C30H30F3N5O/c1-34-29(39)15-10-25-20-28(38(36-25)27-13-11-26(12-14-27)37-18-16-35-17-19-37)23-4-2-21(3-5-23)22-6-8-24(9-7-22)30(31,32)33/h2-9,11-14,20,35H,10,15-19H2,1H3,(H,34,39)
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n/an/a 600n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of human ILK activity assessed myelin basic protein phosphorylation by radiometric kinase assay in the presence of [gamma 32P]ATP


J Med Chem 54: 6364-74 (2011)


Article DOI: 10.1021/jm2007744
BindingDB Entry DOI: 10.7270/Q2513ZKV
More data for this
Ligand-Target Pair
Glucose Transporter 1 (hGLUT1)


(Homo sapiens (Human))
BDBM50388392
PNG
(CHEMBL2058262)
Show SMILES CC(CN1C(=O)S\C(=C/c2ccc(O)c(c2)C(F)(F)F)C1=O)(CC(F)(F)F)CC(F)(F)F
Show InChI InChI=1S/C18H14F9NO3S/c1-15(6-16(19,20)21,7-17(22,23)24)8-28-13(30)12(32-14(28)31)5-9-2-3-11(29)10(4-9)18(25,26)27/h2-5,29H,6-8H2,1H3/b12-5-
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n/an/a 2.00E+3n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of GLUT1 mediated [3H]-2-DG uptake in human LNCAP cells after 30 mins by scintillation counting


J Med Chem 55: 3827-36 (2012)


Article DOI: 10.1021/jm300015m
BindingDB Entry DOI: 10.7270/Q26H4JG2
More data for this
Ligand-Target Pair
Glucose Transporter 1 (hGLUT1)


(Homo sapiens (Human))
BDBM50388391
PNG
(CHEMBL2057965)
Show SMILES CCC(CC)CN1C(=O)S\C(=C/c2ccc(O)c(c2)C(F)(F)F)C1=O
Show InChI InChI=1S/C17H18F3NO3S/c1-3-10(4-2)9-21-15(23)14(25-16(21)24)8-11-5-6-13(22)12(7-11)17(18,19)20/h5-8,10,22H,3-4,9H2,1-2H3/b14-8-
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n/an/a 5.00E+3n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Inhibition of GLUT1 mediated [3H]-2-DG uptake in human LNCAP cells after 30 mins by scintillation counting


J Med Chem 55: 3827-36 (2012)


Article DOI: 10.1021/jm300015m
BindingDB Entry DOI: 10.7270/Q26H4JG2
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078211
PNG
(CHEMBL3414684)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(C)c2N1
Show InChI InChI=1/C17H27NO/c1-12(2)6-5-8-17(4)9-7-14-11-15(19)10-13(3)16(14)18-17/h10-12,18-19H,5-9H2,1-4H3
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078212
PNG
(CHEMBL3414683)
Show SMILES CC(C)CCCC1(C)CCc2ccc(O)c(O)c2O1
Show InChI InChI=1/C16H24O3/c1-11(2)5-4-9-16(3)10-8-12-6-7-13(17)14(18)15(12)19-16/h6-7,11,17-18H,4-5,8-10H2,1-3H3
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n/an/an/a 980n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078213
PNG
(CHEMBL3414682)
Show SMILES CC(C)CCCC1(C)CCc2c(O)cccc2O1
Show InChI InChI=1/C16H24O2/c1-12(2)6-5-10-16(3)11-9-13-14(17)7-4-8-15(13)18-16/h4,7-8,12,17H,5-6,9-11H2,1-3H3
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078214
PNG
(CHEMBL3414681)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(Br)c2O1
Show InChI InChI=1/C16H23BrO2/c1-11(2)5-4-7-16(3)8-6-12-9-13(18)10-14(17)15(12)19-16/h9-11,18H,4-8H2,1-3H3
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n/an/an/a 390n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078215
PNG
(CHEMBL3414680)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(F)c2O1
Show InChI InChI=1/C16H23FO2/c1-11(2)5-4-7-16(3)8-6-12-9-13(18)10-14(17)15(12)19-16/h9-11,18H,4-8H2,1-3H3
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n/an/an/a 340n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078216
PNG
(CHEMBL3414679)
Show SMILES COc1cc(O)cc2CCC(C)(CCCC(C)C)Oc12
Show InChI InChI=1/C17H26O3/c1-12(2)6-5-8-17(3)9-7-13-10-14(18)11-15(19-4)16(13)20-17/h10-12,18H,5-9H2,1-4H3
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n/an/an/a 1.88E+3n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078217
PNG
(CHEMBL3414678)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(O)c2O1
Show InChI InChI=1/C16H24O3/c1-11(2)5-4-7-16(3)8-6-12-9-13(17)10-14(18)15(12)19-16/h9-11,17-18H,4-8H2,1-3H3
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n/an/an/a 1.18E+3n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078218
PNG
(CHEMBL3414677)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(c2O1)C(F)(F)F
Show InChI InChI=1/C17H23F3O2/c1-11(2)5-4-7-16(3)8-6-12-9-13(21)10-14(15(12)22-16)17(18,19)20/h9-11,21H,4-8H2,1-3H3
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n/an/an/a 450n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078219
PNG
(CHEMBL3414676)
Show SMILES CC(C)CCCC1(C)CC(=O)c2cc(O)ccc2O1
Show InChI InChI=1/C16H22O3/c1-11(2)5-4-8-16(3)10-14(18)13-9-12(17)6-7-15(13)19-16/h6-7,9,11,17H,4-5,8,10H2,1-3H3
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n/an/an/a 280n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078220
PNG
(CHEMBL3414675)
Show SMILES CC(C)CCCC1(C)CC(=O)c2cc(O)cc(C)c2O1
Show InChI InChI=1/C17H24O3/c1-11(2)6-5-7-17(4)10-15(19)14-9-13(18)8-12(3)16(14)20-17/h8-9,11,18H,5-7,10H2,1-4H3
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078221
PNG
(CHEMBL3414674)
Show SMILES CC(C)CCCC1(C)CC(=O)c2cc(O)c(C)c(C)c2O1
Show InChI InChI=1/C18H26O3/c1-11(2)7-6-8-18(5)10-16(20)14-9-15(19)12(3)13(4)17(14)21-18/h9,11,19H,6-8,10H2,1-5H3
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n/an/an/a 410n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078222
PNG
(CHEMBL3414673)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)ccc2O1
Show InChI InChI=1/C16H24O2/c1-12(2)5-4-9-16(3)10-8-13-11-14(17)6-7-15(13)18-16/h6-7,11-12,17H,4-5,8-10H2,1-3H3
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n/an/an/a 350n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078223
PNG
(CHEMBL3414672)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)cc(C)c2O1
Show InChI InChI=1/C17H26O2/c1-12(2)6-5-8-17(4)9-7-14-11-15(18)10-13(3)16(14)19-17/h10-12,18H,5-9H2,1-4H3
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078256
PNG
(CHEMBL3414671)
Show SMILES COc1cc2CCC(C)(CCCC(C)C)Oc2c(C)c1C
Show InChI InChI=1/C19H30O2/c1-13(2)8-7-10-19(5)11-9-16-12-17(20-6)14(3)15(4)18(16)21-19/h12-13H,7-11H2,1-6H3
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n/an/an/a 8.50E+3n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078257
PNG
(CHEMBL3414670)
Show SMILES CC(C)CCCC1(C)CCc2cc(O)c(C)c(C)c2O1
Show InChI InChI=1/C18H28O2/c1-12(2)7-6-9-18(5)10-8-15-11-16(19)13(3)14(4)17(15)20-18/h11-12,19H,6-10H2,1-5H3
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078259
PNG
(CHEMBL3414669)
Show SMILES CC(C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |r|
Show InChI InChI=1/C18H28O2/c1-12(2)7-6-9-18(5)10-8-15-11-16(19)13(3)14(4)17(15)20-18/h11-12,19H,6-10H2,1-5H3/t18-/s2
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The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
PH domain leucine-rich repeat-containing protein phosphatase 1


(Homo sapiens (Human))
BDBM50078259
PNG
(CHEMBL3414669)
Show SMILES CC(C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |r|
Show InChI InChI=1/C18H28O2/c1-12(2)7-6-9-18(5)10-8-15-11-16(19)13(3)14(4)17(15)20-18/h11-12,19H,6-10H2,1-5H3/t18-/s2
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n/an/an/a 690n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PHLPP1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
PH domain leucine-rich repeat-containing protein phosphatase 1


(Homo sapiens (Human))
BDBM50078209
PNG
(CHEMBL3414686)
Show SMILES CC(C)CCCC1(C)CCc2cc(c(C)c(C)c2O1)S(N)(=O)=O
Show InChI InChI=1/C18H29NO3S/c1-12(2)7-6-9-18(5)10-8-15-11-16(23(19,20)21)13(3)14(4)17(15)22-18/h11-12H,6-10H2,1-5H3,(H2,19,20,21)
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n/an/an/a 720n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PHLPP1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
PH domain leucine-rich repeat-containing protein phosphatase 1


(Homo sapiens (Human))
BDBM50078207
PNG
(CHEMBL3414688)
Show SMILES CC(C)CCCC1(C)CCc2cc(cc(Br)c2O1)S(N)(=O)=O
Show InChI InChI=1/C16H24BrNO3S/c1-11(2)5-4-7-16(3)8-6-12-9-13(22(18,19)20)10-14(17)15(12)21-16/h9-11H,4-8H2,1-3H3,(H2,18,19,20)
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n/an/an/a 690n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PHLPP1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (Human))
BDBM50078259
PNG
(CHEMBL3414669)
Show SMILES CC(C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |r|
Show InChI InChI=1/C18H28O2/c1-12(2)7-6-9-18(5)10-8-15-11-16(19)13(3)14(4)17(15)20-18/h11-12,19H,6-10H2,1-5H3/t18-/s2
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n/an/an/a 1.02E+4n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PDK1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (Human))
BDBM50078209
PNG
(CHEMBL3414686)
Show SMILES CC(C)CCCC1(C)CCc2cc(c(C)c(C)c2O1)S(N)(=O)=O
Show InChI InChI=1/C18H29NO3S/c1-12(2)7-6-9-18(5)10-8-15-11-16(23(19,20)21)13(3)14(4)17(15)22-18/h11-12H,6-10H2,1-5H3,(H2,19,20,21)
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n/an/an/a 1.95E+4n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PDK1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (Human))
BDBM50078207
PNG
(CHEMBL3414688)
Show SMILES CC(C)CCCC1(C)CCc2cc(cc(Br)c2O1)S(N)(=O)=O
Show InChI InChI=1/C16H24BrNO3S/c1-11(2)5-4-7-16(3)8-6-12-9-13(22(18,19)20)10-14(17)15(12)21-16/h9-11H,4-8H2,1-3H3,(H2,18,19,20)
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n/an/an/a 1.11E+4n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of PDK1 (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM50078259
PNG
(CHEMBL3414669)
Show SMILES CC(C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1 |r|
Show InChI InChI=1/C18H28O2/c1-12(2)7-6-9-18(5)10-8-15-11-16(19)13(3)14(4)17(15)20-18/h11-12,19H,6-10H2,1-5H3/t18-/s2
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n/an/an/a 8.70E+3n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM50078209
PNG
(CHEMBL3414686)
Show SMILES CC(C)CCCC1(C)CCc2cc(c(C)c(C)c2O1)S(N)(=O)=O
Show InChI InChI=1/C18H29NO3S/c1-12(2)7-6-9-18(5)10-8-15-11-16(23(19,20)21)13(3)14(4)17(15)22-18/h11-12H,6-10H2,1-5H3,(H2,19,20,21)
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n/an/an/a 6.20E+3n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase ILK-1


(Homo sapiens (Human))
BDBM50078207
PNG
(CHEMBL3414688)
Show SMILES CC(C)CCCC1(C)CCc2cc(cc(Br)c2O1)S(N)(=O)=O
Show InChI InChI=1/C16H24BrNO3S/c1-11(2)5-4-7-16(3)8-6-12-9-13(22(18,19)20)10-14(17)15(12)21-16/h9-11H,4-8H2,1-3H3,(H2,18,19,20)
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n/an/an/a 1.31E+4n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of ILK (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078210
PNG
(CHEMBL3414685)
Show SMILES CC(C)CCCC1(C)CCc2cc(N)ccc2O1
Show InChI InChI=1/C16H25NO/c1-12(2)5-4-9-16(3)10-8-13-11-14(17)6-7-15(13)18-16/h6-7,11-12H,4-5,8-10,17H2,1-3H3
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n/an/an/a 210n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078209
PNG
(CHEMBL3414686)
Show SMILES CC(C)CCCC1(C)CCc2cc(c(C)c(C)c2O1)S(N)(=O)=O
Show InChI InChI=1/C18H29NO3S/c1-12(2)7-6-9-18(5)10-8-15-11-16(23(19,20)21)13(3)14(4)17(15)22-18/h11-12H,6-10H2,1-5H3,(H2,19,20,21)
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n/an/an/a 200n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078207
PNG
(CHEMBL3414688)
Show SMILES CC(C)CCCC1(C)CCc2cc(cc(Br)c2O1)S(N)(=O)=O
Show InChI InChI=1/C16H24BrNO3S/c1-11(2)5-4-7-16(3)8-6-12-9-13(22(18,19)20)10-14(17)15(12)21-16/h9-11H,4-8H2,1-3H3,(H2,18,19,20)
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n/an/an/a 220n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50078208
PNG
(CHEMBL3414687)
Show SMILES CC(C)CCCC1(C)CCc2cc(cc(F)c2O1)S(N)(=O)=O
Show InChI InChI=1/C16H24FNO3S/c1-11(2)5-4-7-16(3)8-6-12-9-13(22(18,19)20)10-14(17)15(12)21-16/h9-11H,4-8H2,1-3H3,(H2,18,19,20)
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n/an/an/a 350n/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Binding affinity to GST-tagged PH domain of AKT (unknown origin) by surface Plasmon resonance spectroscopy


J Med Chem 58: 2290-8 (2015)


Article DOI: 10.1021/jm501751b
BindingDB Entry DOI: 10.7270/Q20V8FGX
More data for this
Ligand-Target Pair