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Compile Data Set for Download or QSAR

Found 316 hits with Last Name = 'labuda' and Initial = 'cj'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304919
PNG
(CHEMBL595268 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H32N2O4S/c1-6-7-8-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)27(24,25)22-9-11-26-12-10-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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1.10n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277152
PNG
((1S,2S,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Show SMILES Cc1ccc(NC(=O)[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1S(=O)(=O)N1CCOCC1 |r|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-17(13-18(15)29(26,27)24-9-11-28-12-10-24)23-20(25)19-21(2,3)16-7-8-22(19,4)14-16/h5-6,13,16,19H,7-12,14H2,1-4H3,(H,23,25)/t16-,19-,22+/m1/s1
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1.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302304
PNG
(1,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Show SMILES CC1CCCCC1(C)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Show InChI InChI=1S/C20H31N3O2/c1-15-13-21-18(12-17(15)14-23-8-10-25-11-9-23)22-19(24)20(3)7-5-4-6-16(20)2/h12-13,16H,4-11,14H2,1-3H3,(H,21,22,24)
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1.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301311
PNG
((+/-)3,3,3-trifluoro-2-methyl-N-(8-morpholino-5,6,...)
Show SMILES CC(C(=O)Nc1ccc2CCCC(N3CCOCC3)c2c1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H22F6N2O2/c1-17(18(20,21)22,19(23,24)25)16(28)26-13-6-5-12-3-2-4-15(14(12)11-13)27-7-9-29-10-8-27/h5-6,11,15H,2-4,7-10H2,1H3,(H,26,28)
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2.30n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301315
PNG
(CHEMBL568467 | N-(3,4-dimethyl-5-(morpholinomethyl...)
Show SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(CN2CCOCC2)c1C
Show InChI InChI=1S/C18H22F6N2O2/c1-11-8-14(9-13(12(11)2)10-26-4-6-28-7-5-26)25-15(27)16(3,17(19,20)21)18(22,23)24/h8-9H,4-7,10H2,1-3H3,(H,25,27)
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2.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304926
PNG
(CHEMBL602105 | N-(3,4-dimethyl-5-(piperidin-1-ylsu...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCC1
Show InChI InChI=1S/C19H30N2O3S/c1-6-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)25(23,24)21-10-8-7-9-11-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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2.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377711
PNG
(CHEMBL256962)
Show SMILES C[C@@]12CC[C@@H](C1)C(C)(C)[C@H]2NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCOCC1 |THB:10:9:3.2:5|
Show InChI InChI=1S/C21H29BrN2O4S/c1-20(2)15-6-7-21(3,13-15)19(20)23-18(25)14-4-5-16(22)17(12-14)29(26,27)24-8-10-28-11-9-24/h4-5,12,15,19H,6-11,13H2,1-3H3,(H,23,25)/t15-,19+,21+/m0/s1
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3.5n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377707
PNG
(CHEMBL255474)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)N[C@H]1[C@]2(C)CC[C@@H](C2)C1(C)C |THB:18:19:23.22:25|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-16(13-18(15)29(26,27)24-9-11-28-12-10-24)19(25)23-20-21(2,3)17-7-8-22(20,4)14-17/h5-6,13,17,20H,7-12,14H2,1-4H3,(H,23,25)/t17-,20+,22+/m0/s1
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3.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277193
PNG
(4-methyl-3-(morpholinosulfonyl)-N-((1S,2S,4R)-1,3,...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)N[C@H]1[C@@]2(C)CC[C@H](C2)C1(C)C |r|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-16(13-18(15)29(26,27)24-9-11-28-12-10-24)19(25)23-20-21(2,3)17-7-8-22(20,4)14-17/h5-6,13,17,20H,7-12,14H2,1-4H3,(H,23,25)/t17-,20-,22+/m1/s1
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3.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277153
PNG
(4-methyl-3-(morpholinosulfonyl)-N-((1S,2R,4R)-1,3,...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)N[C@@H]1[C@@]2(C)CC[C@H](C2)C1(C)C |r|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-16(13-18(15)29(26,27)24-9-11-28-12-10-24)19(25)23-20-21(2,3)17-7-8-22(20,4)14-17/h5-6,13,17,20H,7-12,14H2,1-4H3,(H,23,25)/t17-,20+,22+/m1/s1
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3.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277194
PNG
(4-(2-methyl-5-(4-neopentylthiazol-2-yl)phenylsulfo...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC(C)(C)C)cs1
Show InChI InChI=1S/C19H26N2O3S2/c1-14-5-6-15(18-20-16(13-25-18)12-19(2,3)4)11-17(14)26(22,23)21-7-9-24-10-8-21/h5-6,11,13H,7-10,12H2,1-4H3
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5.20n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302299
PNG
(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Show SMILES CCCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Show InChI InChI=1S/C18H29N3O2/c1-5-6-18(3,4)17(22)20-16-11-15(14(2)12-19-16)13-21-7-9-23-10-8-21/h11-12H,5-10,13H2,1-4H3,(H,19,20,22)
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5.30n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377706
PNG
(CHEMBL256110)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NC1C2CC3CC(C2)CC1C3 |TLB:18:19:21:25.23.24,THB:23:22:19:25.24.26,23:24:21.22.28:19,26:24:21:28.27.19,26:27:21:25.23.24,(25.81,-25.08,;25.81,-26.62,;24.48,-27.39,;24.48,-28.93,;25.82,-29.71,;27.16,-28.93,;27.15,-27.38,;28.48,-26.61,;29.26,-27.94,;27.71,-25.28,;29.81,-25.83,;31.15,-26.59,;32.48,-25.81,;32.47,-24.27,;31.13,-23.51,;29.8,-24.29,;25.82,-31.25,;24.48,-32.01,;27.15,-32.02,;27.19,-33.56,;25.99,-34.46,;24.26,-34.26,;25.48,-35.21,;25.88,-36.67,;27.5,-36.72,;26.4,-35.81,;28.74,-35.82,;28.36,-34.36,;26.76,-34.26,)|
Show InChI InChI=1S/C22H30N2O4S/c1-14-2-3-17(13-20(14)29(26,27)24-4-6-28-7-5-24)22(25)23-21-18-9-15-8-16(11-18)12-19(21)10-15/h2-3,13,15-16,18-19,21H,4-12H2,1H3,(H,23,25)
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5.60n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277195
PNG
(4-(5-(4-tert-butylthiazol-2-yl)-2-methylphenylsulf...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(cs1)C(C)(C)C
Show InChI InChI=1S/C18H24N2O3S2/c1-13-5-6-14(17-19-16(12-24-17)18(2,3)4)11-15(13)25(21,22)20-7-9-23-10-8-20/h5-6,11-12H,7-10H2,1-4H3
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5.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377705
PNG
(CHEMBL442447)
Show SMILES CC(NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCOCC1)C12CC3CC(CC(C3)C1)C2 |w:1.0,TLB:24:25:29:22.23.28,28:23:30:29.27.26,28:27:30:22.23.24,THB:24:23:29:30.25.26|
Show InChI InChI=1S/C24H34N2O4S/c1-16-3-4-21(12-22(16)31(28,29)26-5-7-30-8-6-26)23(27)25-17(2)24-13-18-9-19(14-24)11-20(10-18)15-24/h3-4,12,17-20H,5-11,13-15H2,1-2H3,(H,25,27)
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6.30n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304916
PNG
(CHEMBL593625 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C17H20F6N2O4S/c1-10-8-12(24-14(26)15(3,16(18,19)20)17(21,22)23)9-13(11(10)2)30(27,28)25-4-6-29-7-5-25/h8-9H,4-7H2,1-3H3,(H,24,26)
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6.60n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304925
PNG
(CHEMBL602128 | N-(3,4-dimethyl-5-(thiazolidin-3-yl...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCSC1
Show InChI InChI=1S/C17H26N2O3S2/c1-6-17(4,5)16(20)18-14-9-12(2)13(3)15(10-14)24(21,22)19-7-8-23-11-19/h9-10H,6-8,11H2,1-5H3,(H,18,20)
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6.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302303
PNG
(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Show SMILES CCC1(CCCCC1)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Show InChI InChI=1S/C20H31N3O2/c1-3-20(7-5-4-6-8-20)19(24)22-18-13-17(16(2)14-21-18)15-23-9-11-25-12-10-23/h13-14H,3-12,15H2,1-2H3,(H,21,22,24)
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7n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302295
PNG
(CHEMBL570792 | N-(5-ethyl-4-(morpholinomethyl)pyri...)
Show SMILES CCc1cnc(NC(=O)C(C)(C)CC)cc1CN1CCOCC1
Show InChI InChI=1S/C18H29N3O2/c1-5-14-12-19-16(20-17(22)18(3,4)6-2)11-15(14)13-21-7-9-23-10-8-21/h11-12H,5-10,13H2,1-4H3,(H,19,20,22)
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7.90n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377704
PNG
(CHEMBL255096)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)N[C@H]1CC2CC[C@@]1(C)C2(C)C |w:21.23,TLB:18:19:23.22:26|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-16(13-18(15)29(26,27)24-9-11-28-12-10-24)20(25)23-19-14-17-7-8-22(19,4)21(17,2)3/h5-6,13,17,19H,7-12,14H2,1-4H3,(H,23,25)/t17?,19-,22+/m0/s1
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8.10n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304935
PNG
(CHEMBL605199 | N-[3-(1,1-Dioxo-1lambda*6*-thiomorp...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCS(=O)(=O)CC1
Show InChI InChI=1S/C18H28N2O5S2/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)27(24,25)20-7-9-26(22,23)10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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8.40n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301316
PNG
(CHEMBL568468 | N-(3,4-dimethyl-5-(morpholinomethyl...)
Show SMILES CC1CCCCC1C(=O)Nc1cc(C)c(C)c(CN2CCOCC2)c1
Show InChI InChI=1S/C21H32N2O2/c1-15-6-4-5-7-20(15)21(24)22-19-12-16(2)17(3)18(13-19)14-23-8-10-25-11-9-23/h12-13,15,20H,4-11,14H2,1-3H3,(H,22,24)
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8.60n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304924
PNG
(CHEMBL602591 | N-(3-(azepan-1-ylsulfonyl)-4,5-dime...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCCCCC1
Show InChI InChI=1S/C20H32N2O3S/c1-6-20(4,5)19(23)21-17-13-15(2)16(3)18(14-17)26(24,25)22-11-9-7-8-10-12-22/h13-14H,6-12H2,1-5H3,(H,21,23)
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9n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277307
PNG
((1S,2R,4R)-1,3,3-trimethyl-N-(4-methyl-3-(morpholi...)
Show SMILES Cc1ccc(NC(=O)[C@@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1S(=O)(=O)N1CCOCC1 |r|
Show InChI InChI=1S/C22H32N2O4S/c1-15-5-6-17(13-18(15)29(26,27)24-9-11-28-12-10-24)23-20(25)19-21(2,3)16-7-8-22(19,4)14-16/h5-6,13,16,19H,7-12,14H2,1-4H3,(H,23,25)/t16-,19+,22+/m1/s1
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9.40n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377710
PNG
(CHEMBL256753)
Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCC1 |THB:10:9:4.5:8|
Show InChI InChI=1S/C21H29BrN2O3S/c1-20(2)15-8-9-21(3,13-15)19(20)23-18(25)14-6-7-16(22)17(12-14)28(26,27)24-10-4-5-11-24/h6-7,12,15,19H,4-5,8-11,13H2,1-3H3,(H,23,25)/t15-,19+,21+/m0/s1
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9.40n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304918
PNG
(CHEMBL595035 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H30N2O4S/c1-6-7-19(4,5)18(22)20-16-12-14(2)15(3)17(13-16)26(23,24)21-8-10-25-11-9-21/h12-13H,6-11H2,1-5H3,(H,20,22)
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9.70n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301311
PNG
((+/-)3,3,3-trifluoro-2-methyl-N-(8-morpholino-5,6,...)
Show SMILES CC(C(=O)Nc1ccc2CCCC(N3CCOCC3)c2c1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H22F6N2O2/c1-17(18(20,21)22,19(23,24)25)16(28)26-13-6-5-12-3-2-4-15(14(12)11-13)27-7-9-29-10-8-27/h5-6,11,15H,2-4,7-10H2,1H3,(H,26,28)
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10n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377703
PNG
(CHEMBL258243)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:23:24:28:21.22.27,27:22:29:28.26.25,27:26:29:21.22.23,THB:23:22:28:29.24.25|
Show InChI InChI=1S/C23H32N2O4S/c1-16-2-3-20(11-21(16)30(27,28)25-4-6-29-7-5-25)22(26)24-15-23-12-17-8-18(13-23)10-19(9-17)14-23/h2-3,11,17-19H,4-10,12-15H2,1H3,(H,24,26)
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10n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277308
PNG
(2-tert-butyl-3,3-dimethyl-N-(4-methyl-3-(morpholin...)
Show SMILES Cc1ccc(NC(=O)C(C(C)(C)C)C(C)(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C21H34N2O4S/c1-15-8-9-16(22-19(24)18(20(2,3)4)21(5,6)7)14-17(15)28(25,26)23-10-12-27-13-11-23/h8-9,14,18H,10-13H2,1-7H3,(H,22,24)
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11n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377709
PNG
(CHEMBL256754)
Show SMILES CN(Cc1ccccc1)S(=O)(=O)c1cc(ccc1Br)C(=O)N[C@@H]1C(C)(C)[C@H]2CC[C@]1(C)C2 |THB:21:22:27.28:31|
Show InChI InChI=1S/C25H31BrN2O3S/c1-24(2)19-12-13-25(3,15-19)23(24)27-22(29)18-10-11-20(26)21(14-18)32(30,31)28(4)16-17-8-6-5-7-9-17/h5-11,14,19,23H,12-13,15-16H2,1-4H3,(H,27,29)/t19-,23+,25+/m0/s1
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11n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277154
PNG
(2,2-dimethyl-N-(4-methyl-3-(morpholinosulfonyl)phe...)
Show SMILES Cc1ccc(NC(=O)C2CCCCC2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-15-7-8-16(21-19(23)17-6-4-5-9-20(17,2)3)14-18(15)27(24,25)22-10-12-26-13-11-22/h7-8,14,17H,4-6,9-13H2,1-3H3,(H,21,23)
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11n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304920
PNG
(2,2-dimethyl-N-(7-(morpholinosulfonyl)-2,3-dihydro...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-4-19(2,3)18(22)20-15-12-14-6-5-7-16(14)17(13-15)26(23,24)21-8-10-25-11-9-21/h12-13H,4-11H2,1-3H3,(H,20,22)
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12n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377708
PNG
(CHEMBL256752)
Show SMILES CC1(C)[C@H]2CC[C@](C)(C2)[C@@H]1NC(=O)c1ccc(Br)c(c1)S(=O)(=O)N1CCCCC1 |THB:10:9:4.5:8|
Show InChI InChI=1S/C22H31BrN2O3S/c1-21(2)16-9-10-22(3,14-16)20(21)24-19(26)15-7-8-17(23)18(13-15)29(27,28)25-11-5-4-6-12-25/h7-8,13,16,20H,4-6,9-12,14H2,1-3H3,(H,24,26)/t16-,20+,22+/m0/s1
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13n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302302
PNG
(1-ethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-...)
Show SMILES CCC1(CCCC1)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Show InChI InChI=1S/C19H29N3O2/c1-3-19(6-4-5-7-19)18(23)21-17-12-16(15(2)13-20-17)14-22-8-10-24-11-9-22/h12-13H,3-11,14H2,1-2H3,(H,20,21,23)
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13n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277155
PNG
(2-methyl-N-(4-methyl-3-(morpholinosulfonyl)phenyl)...)
Show SMILES CC1CCCCC1C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-14-5-3-4-6-17(14)19(22)20-16-8-7-15(2)18(13-16)26(23,24)21-9-11-25-12-10-21/h7-8,13-14,17H,3-6,9-12H2,1-2H3,(H,20,22)
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14n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304921
PNG
(2,2-dimethyl-N-(4-(morpholinosulfonyl)-5,6,7,8-tet...)
Show SMILES CCC(C)(C)C(=O)Nc1cc2CCCCc2c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-4-20(2,3)19(23)21-16-13-15-7-5-6-8-17(15)18(14-16)27(24,25)22-9-11-26-12-10-22/h13-14H,4-12H2,1-3H3,(H,21,23)
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14n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304914
PNG
(CHEMBL593166 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES Cc1cc(NC(=O)C2C(C)(C)C2(C)C)cc(c1C)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C20H30N2O4S/c1-13-11-15(21-18(23)17-19(3,4)20(17,5)6)12-16(14(13)2)27(24,25)22-7-9-26-10-8-22/h11-12,17H,7-10H2,1-6H3,(H,21,23)
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16n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301312
PNG
(3,3-difluoro-2-methyl-N-(4-methyl-3-(morpholinomet...)
Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1CN1CCOCC1
Show InChI InChI=1S/C17H20F6N2O2/c1-11-3-4-13(9-12(11)10-25-5-7-27-8-6-25)24-14(26)15(2,16(18,19)20)17(21,22)23/h3-4,9H,5-8,10H2,1-2H3,(H,24,26)
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16n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301306
PNG
(2-methyl-N-(4-methyl-3-(morpholinomethyl)-5-(trifl...)
Show SMILES CC1CCCCC1C(=O)Nc1cc(CN2CCOCC2)c(C)c(c1)C(F)(F)F
Show InChI InChI=1S/C21H29F3N2O2/c1-14-5-3-4-6-18(14)20(27)25-17-11-16(13-26-7-9-28-10-8-26)15(2)19(12-17)21(22,23)24/h11-12,14,18H,3-10,13H2,1-2H3,(H,25,27)
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17n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50304917
PNG
(CHEMBL596401 | N-(3,4-dimethyl-5-(morpholinosulfon...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C18H28N2O4S/c1-6-18(4,5)17(21)19-15-11-13(2)14(3)16(12-15)25(22,23)20-7-9-24-10-8-20/h11-12H,6-10H2,1-5H3,(H,19,21)
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17n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277196
PNG
(4-(2-methyl-5-(2-neopentyl-2H-tetrazol-5-yl)phenyl...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnn(CC(C)(C)C)n1
Show InChI InChI=1S/C17H25N5O3S/c1-13-5-6-14(16-18-20-22(19-16)12-17(2,3)4)11-15(13)26(23,24)21-7-9-25-10-8-21/h5-6,11H,7-10,12H2,1-4H3
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17n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377702
PNG
(CHEMBL258244)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:22:23:27:20.21.26,26:21:28:27.25.24,26:25:28:20.21.22,THB:22:21:27:28.23.24|
Show InChI InChI=1S/C22H30N2O4S/c1-15-2-3-19(11-20(15)29(26,27)24-4-6-28-7-5-24)21(25)23-22-12-16-8-17(13-22)10-18(9-16)14-22/h2-3,11,16-18H,4-10,12-14H2,1H3,(H,23,25)
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19n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cloned CB2 receptor


Bioorg Med Chem Lett 18: 2830-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.006
BindingDB Entry DOI: 10.7270/Q2P2701M
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50301317
PNG
(4-methyl-3-(morpholinomethyl)-N-((1S,4R)-1,3,3-tri...)
Show SMILES Cc1ccc(cc1CN1CCOCC1)C(=O)NC1[C@@]2(C)CC[C@H](C2)C1(C)C |r|
Show InChI InChI=1S/C23H34N2O2/c1-16-5-6-17(13-18(16)15-25-9-11-27-12-10-25)20(26)24-21-22(2,3)19-7-8-23(21,4)14-19/h5-6,13,19,21H,7-12,14-15H2,1-4H3,(H,24,26)/t19-,21?,23+/m1/s1
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19n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 19: 5004-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.057
BindingDB Entry DOI: 10.7270/Q25M65S1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277267
PNG
(4-(5-(4-tert-butyl-1H-imidazol-2-yl)-2-methylpheny...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(c[nH]1)C(C)(C)C
Show InChI InChI=1S/C18H25N3O3S/c1-13-5-6-14(17-19-12-16(20-17)18(2,3)4)11-15(13)25(22,23)21-7-9-24-10-8-21/h5-6,11-12H,7-10H2,1-4H3,(H,19,20)
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277309
PNG
(3,3,3-trifluoro-2-methyl-N-(4-methyl-3-(morpholino...)
Show SMILES Cc1ccc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C16H18F6N2O4S/c1-10-3-4-11(9-12(10)29(26,27)24-5-7-28-8-6-24)23-13(25)14(2,15(17,18)19)16(20,21)22/h3-4,9H,5-8H2,1-2H3,(H,23,25)
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277339
PNG
(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Show SMILES Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-13-6-7-14(20-17(22)16-18(2,3)19(16,4)5)12-15(13)26(23,24)21-8-10-25-11-9-21/h6-7,12,16H,8-11H2,1-5H3,(H,20,22)
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277192
PNG
(4-(5-(4-(cyclohexylmethyl)thiazol-2-yl)-2-methylph...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nc(CC2CCCCC2)cs1
Show InChI InChI=1S/C21H28N2O3S2/c1-16-7-8-18(14-20(16)28(24,25)23-9-11-26-12-10-23)21-22-19(15-27-21)13-17-5-3-2-4-6-17/h7-8,14-15,17H,2-6,9-13H2,1H3
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277339
PNG
(2,2,3,3-tetramethyl-N-(4-methyl-3-(morpholinosulfo...)
Show SMILES Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(=O)(=O)N1CCOCC1
Show InChI InChI=1S/C19H28N2O4S/c1-13-6-7-14(20-17(22)16-18(2,3)19(16,4)5)12-15(13)26(23,24)21-8-10-25-11-9-21/h6-7,12,16H,8-11H2,1-5H3,(H,20,22)
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23n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human CB2 receptor


Bioorg Med Chem Lett 20: 387-91 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.062
BindingDB Entry DOI: 10.7270/Q27P8ZGK
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50302305
PNG
(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Show SMILES CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1
Show InChI InChI=1S/C17H27N3O2/c1-5-17(3,4)16(21)19-15-10-14(13(2)11-18-15)12-20-6-8-22-9-7-20/h10-11H,5-9,12H2,1-4H3,(H,18,19,21)
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24n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopy


Bioorg Med Chem Lett 19: 5931-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.063
BindingDB Entry DOI: 10.7270/Q2HQ4001
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50277227
PNG
(4-(5-(5-(cyclohexylmethyl)-1H-1,2,4-triazol-3-yl)-...)
Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)-c1nnc(CC2CCCCC2)[nH]1
Show InChI InChI=1S/C20H28N4O3S/c1-15-7-8-17(14-18(15)28(25,26)24-9-11-27-12-10-24)20-21-19(22-23-20)13-16-5-3-2-4-6-16/h7-8,14,16H,2-6,9-13H2,1H3,(H,21,22,23)
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27n/an/an/an/an/an/an/an/a



Adolor Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from human cloned CB2 receptor by scintillation spectrometry


Bioorg Med Chem Lett 19: 309-13 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.091
BindingDB Entry DOI: 10.7270/Q2G73DK3
More data for this
Ligand-Target Pair
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