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Compile Data Set for Download or QSAR

Found 357 hits with Last Name = 'lawson' and Initial = 'jd'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50389606
PNG
(CHEMBL2069625)
Show SMILES Cc1oc(nc1COc1cccc(CO)c1)-c1ccccc1
Show InChI InChI=1S/C18H17NO3/c1-13-17(12-21-16-9-5-6-14(10-16)11-20)19-18(22-13)15-7-3-2-4-8-15/h2-10,20H,11-12H2,1H3
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2.50E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human unphosphorylated N-terminal-His6 tagged VEGFR2 catalytic domain using 5-FAM-EEPLYWSFPAKKK-CONH2 as substrate after 60 mins by mob...


ACS Med Chem Lett 3: 342-346 (2012)


Article DOI: 10.1021/ml3000403
BindingDB Entry DOI: 10.7270/Q2FN1782
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238063
PNG
(CHEMBL4101751)
Show SMILES CNC(=O)n1ncc2nccc(Nc3cc(ncc3C)-c3cc(F)ccc3F)c12
PDB

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n/an/a 1n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238082
PNG
(CHEMBL4102696)
Show SMILES Cc1cnc(cc1Nc1ccnc2cn[nH]c12)-c1cc(F)ccc1F
PDB

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n/an/a 1n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM50234304
PNG
(CHEMBL4062894)
Show SMILES CS(=O)(=O)N1CCC[C@@H](C1)c1csc(n1)-c1cc(ccc1NC(=O)c1ncc[nH]1)N1CCNCC1 |r|
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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1099-1104 (2017)


BindingDB Entry DOI: 10.7270/Q2D50Q6F
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 22
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-8-fluoro...)
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n/an/a<1.26n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 23
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-fluo...)
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n/an/a<1.26n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 24
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-7-chloro...)
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n/an/a<1.26n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 27
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-8-chloro...)
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n/an/a<1.26n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350338
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-8-fluoro...)
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n/an/a<1.26n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350339
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-fluo...)
PDB
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n/an/a<1.26n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350340
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-7-chloro...)
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n/an/a<1.26n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350343
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)-8-chloro...)
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n/an/a<1.26n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM50234305
PNG
(CHEMBL4090103)
Show SMILES CN(C)CCOc1ccc(NC(=O)c2ncc[nH]2)c(c1)-c1nc(cs1)[C@H]1CCCN(C1)S(C)(=O)=O |r|
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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1099-1104 (2017)


BindingDB Entry DOI: 10.7270/Q2D50Q6F
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238072
PNG
(CHEMBL4104104)
Show SMILES CCn1ncc2nccc(Nc3cc(ncc3C)-c3cc(C)ccc3F)c12
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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350321
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinol...)
PDB
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Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 5
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinol...)
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n/an/a<2n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM50097393
PNG
(CHEMBL3586447)
Show SMILES Cc1cc2cn[nH]c2cc1-c1cccc2c(N)c(nnc12)C(N)=O
Show InChI InChI=1S/C17H14N6O/c1-8-5-9-7-20-21-13(9)6-12(8)10-3-2-4-11-14(18)16(17(19)24)23-22-15(10)11/h2-7H,1H3,(H2,18,22)(H2,19,24)(H,20,21)
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n/an/a 2n/an/an/an/an/an/a



Takeda California, 10410 Science Center Drive, San Diego, California 92121, United States.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Btk


J Med Chem 58: 5437-44 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00734
BindingDB Entry DOI: 10.7270/Q25B047D
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM50234306
PNG
(CHEMBL4094158)
Show SMILES CS(=O)(=O)N1CCO[C@@H](C1)c1csc(n1)-c1cc(ccc1NC(=O)c1ncc[nH]1)N1CCOCC1 |r|
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n/an/a 2.20n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1099-1104 (2017)


BindingDB Entry DOI: 10.7270/Q2D50Q6F
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238093
PNG
(CHEMBL4094958)
Show SMILES COc1cccc2nccc(Nc3cc(ncc3C)-c3nc(C)ccc3F)c12
PDB

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n/an/a 2.5n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238056
PNG
(CHEMBL4060987)
Show SMILES CNC(=O)n1ncc2nccc(Nc3ccnc(c3)-c3cc(F)ccc3F)c12
PDB

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n/an/a 2.5n/an/an/an/an/an/a



Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 28
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-chlo...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 29
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-meth...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 30
PNG
((S)-3-(6-((1-acryloylpyrrolidin-3-yl)oxy)-4-methyl...)
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n/an/a<2.51n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 34
PNG
((S)-5-(1-((1-(2-chloroacetyl)pyrrolidin-3-yl)amino...)
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n/an/a<2.51n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350324
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)isoquin...)
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350333
PNG
((S)-3-(8-((1-acryloylpyrrolidin-3-yl)amino)-1,7-na...)
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350336
PNG
(3-(1-(((3R,4S)-1-acryloyl-4-methylpyrrolidin-3-yl)...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350341
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-7-fluo...)
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350342
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-7-chlo...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350344
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-chlo...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350345
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-8-meth...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350346
PNG
((S)-3-(6-((1-acryloylpyrrolidin-3-yl)oxy)-4-methyl...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350350
PNG
((S)-5-(1-((1-(2-chloroacetyl)pyrrolidin-3-yl)amino...)
PDB
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n/an/a<2.51n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 8
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)isoquin...)
PDB
MMDB

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n/an/a<2.51n/an/an/an/an/an/a



CNRS





Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 26
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-7-chlo...)
PDB
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 25
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)amino)-7-fluo...)
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 17
PNG
((S)-3-(8-((1-acryloylpyrrolidin-3-yl)amino)-1,7-na...)
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 20
PNG
(3-(1-(((3R,4S)-1-acryloyl-4-methylpyrrolidin-3-yl)...)
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM110223
PNG
(US8618290, 61)
Show SMILES COc1cccc(n1)-c1cc(F)ccc1[C@H]1Cc2nc(N)nc(C)c2C(NO)=N1 |r,c:30|
Show InChI InChI=1S/C20H19FN6O2/c1-10-18-16(26-20(22)23-10)9-15(25-19(18)27-28)12-7-6-11(21)8-13(12)14-4-3-5-17(24-14)29-2/h3-8,15,28H,9H2,1-2H3,(H,25,27)(H2,22,23,26)/t15-/m1/s1
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US Patent
n/an/a 3n/an/an/an/a7.3n/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...


US Patent US8618290 (2013)


BindingDB Entry DOI: 10.7270/Q2D50KM5
More data for this
Ligand-Target Pair
Microtubule-associated protein 2


(Homo sapiens (Human))
BDBM50167916
PNG
(CHEMBL3798615)
Show SMILES FC(F)(F)c1cc(-c2cncc(c2)C#N)c2cn[nH]c2c1
Show InChI InChI=1S/C14H7F3N4/c15-14(16,17)10-2-11(12-7-20-21-13(12)3-10)9-1-8(4-18)5-19-6-9/h1-3,5-7H,(H,20,21)
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Takeda California

Curated by ChEMBL


Assay Description
Reversal inhibition of full length recombinant human MetAP2 expressed in baculovirus infected insect Sf9 cells using Met-AMC as substrate measured fo...


Bioorg Med Chem Lett 26: 2774-2778 (2016)


Article DOI: 10.1016/j.bmcl.2016.04.073
BindingDB Entry DOI: 10.7270/Q2DF6T4T
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 16
PNG
((S)-3-(8-((1-acryloylpyrrolidin-3-yl)oxy)-1,7-naph...)
PDB
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350327
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)(methyl)amino...)
PDB
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n/an/a 3.16n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
US10307414, Example 11
PNG
((S)-3-(1-((1-acryloylpyrrolidin-3-yl)(methyl)amino...)
PDB
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Bioorg Med Chem Lett 19: 1600-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.008
More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM350332
PNG
((S)-3-(8-((1-acryloylpyrrolidin-3-yl)oxy)-1,7-naph...)
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n/an/a<3.16n/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent




US Patent US9801872 (2017)


BindingDB Entry DOI: 10.7270/Q2BC41PD
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238084
PNG
(CHEMBL4085333)
Show SMILES CC(O)Cn1ncc2nccc(Nc3cc(ncc3C)-c3cc(F)ccc3F)c12
PDB

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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238074
PNG
(CHEMBL4075003)
Show SMILES Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cnn(CC(N)=O)c23)c(C)cn1
PDB

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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238064
PNG
(CHEMBL4063730)
Show SMILES CNC(=O)n1ncc2nccc(Nc3ccnc(c3)-c3cc(Cl)ccc3F)c12
PDB

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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase receptor UFO


(Homo sapiens (Human))
BDBM50234303
PNG
(CHEMBL4066616)
Show SMILES CS(=O)(=O)N1CCC[C@@H](C1)c1csc(n1)-c1cc(ccc1NC(=O)c1ncc[nH]1)N1CCOCC1 |r|
PDB

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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1099-1104 (2017)


BindingDB Entry DOI: 10.7270/Q2D50Q6F
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238071
PNG
(CHEMBL4079857)
Show SMILES Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cnn(C)c23)c(C)cn1
PDB

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Takeda California

Curated by ChEMBL




Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50238057
PNG
(CHEMBL4085263)
Show SMILES Cc1ccc(F)c(c1)-c1cc(Nc2ccnc3cn(C)nc23)c(C)cn1
PDB

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Bioorg Med Chem Lett 27: 1955-1961 (2017)


Article DOI: 10.1016/j.bmcl.2017.03.026
BindingDB Entry DOI: 10.7270/Q2QJ7KKZ
More data for this
Ligand-Target Pair
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