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Compile Data Set for Download or QSAR

Found 116 hits with Last Name = 'lemahieu' and Initial = 'ra'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018388
PNG
(5,5-Bis-(3-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1cccc(c1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(-[#8]-[#6])c1
Show InChI InChI=1S/C28H30N2O3/c1-32-25-13-5-11-23(19-25)27(24-12-6-14-26(20-24)33-2)15-7-16-28(31)30-18-4-3-9-22-10-8-17-29-21-22/h5-8,10-17,19-21H,3-4,9,18H2,1-2H3,(H,30,31)/b16-7+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018350
PNG
(5-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-dienoic ac...)
Show SMILES COc1ccc(cc1)C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)\c1ccccc1
Show InChI InChI=1S/C28H30N2O2/c1-22(9-6-10-23-11-8-20-29-21-23)30-28(31)15-7-14-27(24-12-4-3-5-13-24)25-16-18-26(32-2)19-17-25/h3-5,7-8,11-22H,6,9-10H2,1-2H3,(H,30,31)/b15-7+,27-14+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018392
PNG
(5-(4-Methoxy-phenyl)-5-phenyl-penta-2,4-dienoic ac...)
Show SMILES COc1ccc(cc1)C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)\c1ccccc1
Show InChI InChI=1S/C28H30N2O2/c1-22(9-6-10-23-11-8-20-29-21-23)30-28(31)15-7-14-27(24-12-4-3-5-13-24)25-16-18-26(32-2)19-17-25/h3-5,7-8,11-22H,6,9-10H2,1-2H3,(H,30,31)/b15-7+,27-14-/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018316
PNG
(2-Butyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid...)
Show SMILES CCCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C29H36N2O3/c1-5-6-12-23-18-25(13-15-26(23)24-14-16-27(33-3)28(19-24)34-4)29(32)31-21(2)9-7-10-22-11-8-17-30-20-22/h8,11,13-21H,5-7,9-10,12H2,1-4H3,(H,31,32)/t21-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018341
PNG
(2-Ethyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid...)
Show SMILES CCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C27H32N2O3/c1-5-21-16-23(11-13-24(21)22-12-14-25(31-3)26(17-22)32-4)27(30)29-19(2)8-6-9-20-10-7-15-28-18-20/h7,10-19H,5-6,8-9H2,1-4H3,(H,29,30)/t19-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018315
PNG
(2-Ethynyl-3',4'-dimethoxy-biphenyl-4-carboxylic ac...)
Show SMILES COc1ccc(cc1OC)-c1ccc(cc1C#C)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C27H28N2O3/c1-5-21-16-23(11-13-24(21)22-12-14-25(31-3)26(17-22)32-4)27(30)29-19(2)8-6-9-20-10-7-15-28-18-20/h1,7,10-19H,6,8-9H2,2-4H3,(H,29,30)/t19-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50283416
PNG
(4-[7-(2,3-Dihydroxy-phenyl)-heptyloxy]-2-hydroxy-3...)
Show SMILES CCCc1c(O)c(ccc1OCCCCCCCc1cccc(O)c1O)C(O)=O
Show InChI InChI=1S/C23H30O6/c1-2-9-17-20(14-13-18(22(17)26)23(27)28)29-15-7-5-3-4-6-10-16-11-8-12-19(24)21(16)25/h8,11-14,24-26H,2-7,9-10,15H2,1H3,(H,27,28)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018325
PNG
(CHEMBL53584 | [1,1';2',1'']Terphenyl-4'-carboxylic...)
Show SMILES O=C(NCCCCc1cccnc1)c1ccc(-c2ccccc2)c(c1)-c1ccccc1
Show InChI InChI=1S/C28H26N2O/c31-28(30-19-8-7-10-22-11-9-18-29-21-22)25-16-17-26(23-12-3-1-4-13-23)27(20-25)24-14-5-2-6-15-24/h1-6,9,11-18,20-21H,7-8,10,19H2,(H,30,31)
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018390
PNG
(5-(4-Methoxy-phenyl)-trideca-2,4-dienoic acid (1-m...)
Show SMILES CCCCCCCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C30H42N2O2/c1-4-5-6-7-8-9-16-27(28-19-21-29(34-3)22-20-28)17-11-18-30(33)32-25(2)13-10-14-26-15-12-23-31-24-26/h11-12,15,17-25H,4-10,13-14,16H2,1-3H3,(H,32,33)/b18-11+,27-17+/t25-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50283408
PNG
(4-[5-(2,3-Dihydroxy-phenyl)-pentyloxy]-2-hydroxy-3...)
Show SMILES CCCc1c(O)c(ccc1OCCCCCc1cccc(O)c1O)C(O)=O
Show InChI InChI=1S/C21H26O6/c1-2-7-15-18(12-11-16(20(15)24)21(25)26)27-13-5-3-4-8-14-9-6-10-17(22)19(14)23/h6,9-12,22-24H,2-5,7-8,13H2,1H3,(H,25,26)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018361
PNG
(5-(4-Methoxy-phenyl)-undeca-2,4-dienoic acid (1-me...)
Show SMILES CCCCCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C28H38N2O2/c1-4-5-6-7-14-25(26-17-19-27(32-3)20-18-26)15-9-16-28(31)30-23(2)11-8-12-24-13-10-21-29-22-24/h9-10,13,15-23H,4-8,11-12,14H2,1-3H3,(H,30,31)/b16-9+,25-15+/t23-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM22372
PNG
(4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbut...)
Show SMILES C[C@@H](Cc1ccc(O)c(O)c1)[C@H](C)Cc1ccc(O)c(O)c1
Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018349
PNG
(5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid (1-meth...)
Show SMILES CCCCC\C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C27H36N2O2/c1-4-5-6-13-24(25-16-18-26(31-3)19-17-25)14-8-15-27(30)29-22(2)10-7-11-23-12-9-20-28-21-23/h8-9,12,14-22H,4-7,10-11,13H2,1-3H3,(H,29,30)/b15-8+,24-14-/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018347
PNG
(5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-c1ccc(cc1)-c1cccnc1)\c1ccc(-[#8]-[#6])cc1
Show InChI InChI=1S/C30H26N2O3/c1-34-27-16-10-23(11-17-27)29(24-12-18-28(35-2)19-13-24)6-3-7-30(33)32-26-14-8-22(9-15-26)25-5-4-20-31-21-25/h3-21H,1-2H3,(H,32,33)/b7-3+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018393
PNG
(5-(4-Methoxy-phenyl)-nona-2,4-dienoic acid (1-meth...)
Show SMILES CCCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C26H34N2O2/c1-4-5-12-23(24-15-17-25(30-3)18-16-24)13-7-14-26(29)28-21(2)9-6-10-22-11-8-19-27-20-22/h7-8,11,13-21H,4-6,9-10,12H2,1-3H3,(H,28,29)/b14-7+,23-13+/t21-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018321
PNG
(3',4'-Dimethoxy-biphenyl-4-carboxylic acid (1-meth...)
Show SMILES COc1ccc(cc1OC)-c1ccc(cc1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C25H28N2O3/c1-18(6-4-7-19-8-5-15-26-17-19)27-25(28)21-11-9-20(10-12-21)22-13-14-23(29-2)24(16-22)30-3/h5,8-18H,4,6-7H2,1-3H3,(H,27,28)/t18-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018338
PNG
(2-Butyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid...)
Show SMILES CCCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)NCCCCc1cccnc1
Show InChI InChI=1S/C28H34N2O3/c1-4-5-11-22-18-24(28(31)30-17-7-6-9-21-10-8-16-29-20-21)12-14-25(22)23-13-15-26(32-2)27(19-23)33-3/h8,10,12-16,18-20H,4-7,9,11,17H2,1-3H3,(H,30,31)
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018371
PNG
(5,5-Bis-(3-fluoro-phenyl)-penta-2,4-dienoic acid (...)
Show SMILES Fc1cccc(c1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(F)c1
Show InChI InChI=1S/C26H24F2N2O/c27-23-11-3-9-21(17-23)25(22-10-4-12-24(28)18-22)13-5-14-26(31)30-16-2-1-7-20-8-6-15-29-19-20/h3-6,8-15,17-19H,1-2,7,16H2,(H,30,31)/b14-5+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50283414
PNG
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-3-propyl-ben...)
Show SMILES CCCc1cc(ccc1OCCCCCCc1cccc(O)c1O)C(O)=O
Show InChI InChI=1S/C22H28O5/c1-2-8-17-15-18(22(25)26)12-13-20(17)27-14-6-4-3-5-9-16-10-7-11-19(23)21(16)24/h7,10-13,15,23-24H,2-6,8-9,14H2,1H3,(H,25,26)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018337
PNG
(3'-Methoxy-biphenyl-4-carboxylic acid (1-methyl-4-...)
Show SMILES COc1cccc(c1)-c1ccc(cc1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C24H26N2O2/c1-18(6-3-7-19-8-5-15-25-17-19)26-24(27)21-13-11-20(12-14-21)22-9-4-10-23(16-22)28-2/h4-5,8-18H,3,6-7H2,1-2H3,(H,26,27)/t18-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50283409
PNG
(4-[6-(2,3-Dihydroxy-phenyl)-hexyloxy]-2-hydroxy-3-...)
Show SMILES CCCc1c(O)c(ccc1OCCCCCCc1cccc(O)c1O)C(O)=O
Show InChI InChI=1S/C22H28O6/c1-2-8-16-19(13-12-17(21(16)25)22(26)27)28-14-6-4-3-5-9-15-10-7-11-18(23)20(15)24/h7,10-13,23-25H,2-6,8-9,14H2,1H3,(H,26,27)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018368
PNG
(5-Cyclohexyl-5-(4-methoxy-phenyl)-penta-2,4-dienoi...)
Show SMILES COc1ccc(cc1)C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)\C1CCCCC1
Show InChI InChI=1S/C28H36N2O2/c1-22(9-6-10-23-11-8-20-29-21-23)30-28(31)15-7-14-27(24-12-4-3-5-13-24)25-16-18-26(32-2)19-17-25/h7-8,11,14-22,24H,3-6,9-10,12-13H2,1-2H3,(H,30,31)/b15-7+,27-14-/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Arachidonate 5-lipoxygenase


(Rattus norvegicus)
BDBM50283407
PNG
(4-[10-(2,3-Dihydroxy-phenyl)-decyloxy]-2-hydroxy-3...)
Show SMILES CCCc1c(O)c(ccc1OCCCCCCCCCCc1cccc(O)c1O)C(O)=O
Show InChI InChI=1S/C26H36O6/c1-2-12-20-23(17-16-21(25(20)29)26(30)31)32-18-10-8-6-4-3-5-7-9-13-19-14-11-15-22(27)24(19)28/h11,14-17,27-29H,2-10,12-13,18H2,1H3,(H,30,31)
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TBA

Curated by ChEMBL


Assay Description
Inhibition of 5-lipoxygenase from rat basophilic leukemia(RBL-1) cells


Bioorg Med Chem Lett 4: 339-344 (1994)


Article DOI: 10.1016/S0960-894X(01)80140-2
BindingDB Entry DOI: 10.7270/Q2W095WT
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018372
PNG
(5-Cyclohexyl-5-(4-methoxy-phenyl)-penta-2,4-dienoi...)
Show SMILES COc1ccc(cc1)C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)\C1CCCCC1
Show InChI InChI=1S/C28H36N2O2/c1-22(9-6-10-23-11-8-20-29-21-23)30-28(31)15-7-14-27(24-12-4-3-5-13-24)25-16-18-26(32-2)19-17-25/h7-8,11,14-22,24H,3-6,9-10,12-13H2,1-2H3,(H,30,31)/b15-7+,27-14+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018380
PNG
(5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])cc1
Show InChI InChI=1S/C28H30N2O3/c1-32-25-15-11-23(12-16-25)27(24-13-17-26(33-2)18-14-24)9-5-10-28(31)30-20-4-3-7-22-8-6-19-29-21-22/h5-6,8-19,21H,3-4,7,20H2,1-2H3,(H,30,31)/b10-5+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018379
PNG
(5-(4-Methoxy-phenyl)-hexa-2,4-dienoic acid (1-meth...)
Show SMILES COc1ccc(cc1)C(\C)=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C23H28N2O2/c1-18(21-12-14-22(27-3)15-13-21)7-4-11-23(26)25-19(2)8-5-9-20-10-6-16-24-17-20/h4,6-7,10-17,19H,5,8-9H2,1-3H3,(H,25,26)/b11-4+,18-7+/t19-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018356
PNG
(5-(3-Fluoro-phenyl)-5-(3-methoxy-phenyl)-penta-2,4...)
Show SMILES COc1cccc(c1)C(=C/C=C/C(=O)NCCCCc1cccnc1)\c1cccc(F)c1
Show InChI InChI=1S/C27H27FN2O2/c1-32-25-13-5-11-23(19-25)26(22-10-4-12-24(28)18-22)14-6-15-27(31)30-17-3-2-8-21-9-7-16-29-20-21/h4-7,9-16,18-20H,2-3,8,17H2,1H3,(H,30,31)/b15-6+,26-14-
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018376
PNG
(5,5-Bis-(3-chloro-phenyl)-penta-2,4-dienoic acid (...)
Show SMILES Clc1cccc(c1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(Cl)c1
Show InChI InChI=1S/C26H24Cl2N2O/c27-23-11-3-9-21(17-23)25(22-10-4-12-24(28)18-22)13-5-14-26(31)30-16-2-1-7-20-8-6-15-29-19-20/h3-6,8-15,17-19H,1-2,7,16H2,(H,30,31)/b14-5+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018370
PNG
(5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6](-[#6])-[#6]-[#6]-[#6]-c1cccnc1-[#6])\c1ccc(-[#8]-[#6])cc1
Show InChI InChI=1S/C30H34N2O3/c1-22(8-5-9-24-10-7-21-31-23(24)2)32-30(33)12-6-11-29(25-13-17-27(34-3)18-14-25)26-15-19-28(35-4)20-16-26/h6-7,10-22H,5,8-9H2,1-4H3,(H,32,33)/b12-6+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018395
PNG
(5-(4-Methoxy-phenyl)-penta-2,4-dienoic acid (1-met...)
Show SMILES COc1ccc(\C=C\C=C\C(=O)N[C@H](C)CCCc2cccnc2)cc1
Show InChI InChI=1S/C22H26N2O2/c1-18(7-5-9-20-10-6-16-23-17-20)24-22(25)11-4-3-8-19-12-14-21(26-2)15-13-19/h3-4,6,8,10-18H,5,7,9H2,1-2H3,(H,24,25)/b8-3+,11-4+/t18-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018384
PNG
(5-(4-Methoxy-phenyl)-hepta-2,4-dienoic acid (1-met...)
Show SMILES CC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C24H30N2O2/c1-4-21(22-13-15-23(28-3)16-14-22)11-6-12-24(27)26-19(2)8-5-9-20-10-7-17-25-18-20/h6-7,10-19H,4-5,8-9H2,1-3H3,(H,26,27)/b12-6+,21-11+/t19-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018396
PNG
(5,5-Bis-(3-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1cccc(c1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1cccc(-[#8]-[#6])c1
Show InChI InChI=1S/C29H32N2O3/c1-22(9-4-10-23-11-8-18-30-21-23)31-29(32)17-7-16-28(24-12-5-14-26(19-24)33-2)25-13-6-15-27(20-25)34-3/h5-8,11-22H,4,9-10H2,1-3H3,(H,31,32)/b17-7+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50006812
PNG
(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Show SMILES CCCc1c(OCC(O)COc2ccc3c(oc(cc3=O)C(O)=O)c2CCC)ccc(C(C)=O)c1O
Show InChI InChI=1S/C27H30O9/c1-4-6-19-22(10-8-17(15(3)28)25(19)31)34-13-16(29)14-35-23-11-9-18-21(30)12-24(27(32)33)36-26(18)20(23)7-5-2/h8-12,16,29,31H,4-7,13-14H2,1-3H3,(H,32,33)
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TBA

Curated by ChEMBL




J Med Chem 30: 173-8 (1987)


BindingDB Entry DOI: 10.7270/Q2D220TJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011671
PNG
((2E,4E)-5-(4-Methoxy-phenyl)-deca-2,4-dienoic acid...)
Show SMILES CCCCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C27H36N2O2/c1-4-5-6-13-24(25-16-18-26(31-3)19-17-25)14-8-15-27(30)29-22(2)10-7-11-23-12-9-20-28-21-23/h8-9,12,14-22H,4-7,10-11,13H2,1-3H3,(H,29,30)/b15-8+,24-14+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018382
PNG
(5,5-Bis-(4-fluoro-phenyl)-penta-2,4-dienoic acid (...)
Show SMILES Fc1ccc(cc1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(F)cc1
Show InChI InChI=1S/C26H24F2N2O/c27-23-13-9-21(10-14-23)25(22-11-15-24(28)16-12-22)7-3-8-26(31)30-18-2-1-5-20-6-4-17-29-19-20/h3-4,6-17,19H,1-2,5,18H2,(H,30,31)/b8-3+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018360
PNG
(5-(4-Methoxy-phenyl)-6-methyl-hepta-2,4-dienoic ac...)
Show SMILES COc1ccc(cc1)C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)\C(C)C
Show InChI InChI=1S/C25H32N2O2/c1-19(2)24(22-13-15-23(29-4)16-14-22)11-6-12-25(28)27-20(3)8-5-9-21-10-7-17-26-18-21/h6-7,10-20H,5,8-9H2,1-4H3,(H,27,28)/b12-6+,24-11+/t20-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018359
PNG
(5,5-Bis-(2-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccccc1\[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)-c1ccccc1-[#8]-[#6]
Show InChI InChI=1S/C28H30N2O3/c1-32-26-16-5-3-13-24(26)23(25-14-4-6-17-27(25)33-2)15-9-18-28(31)30-20-8-7-11-22-12-10-19-29-21-22/h3-6,9-10,12-19,21H,7-8,11,20H2,1-2H3,(H,30,31)/b18-9+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018375
PNG
(5-(3-Fluoro-phenyl)-5-(3-methoxy-phenyl)-penta-2,4...)
Show SMILES COc1cccc(c1)C(=C\C=C\C(=O)NCCCCc1cccnc1)\c1cccc(F)c1
Show InChI InChI=1S/C27H27FN2O2/c1-32-25-13-5-11-23(19-25)26(22-10-4-12-24(28)18-22)14-6-15-27(31)30-17-3-2-8-21-9-7-16-29-20-21/h4-7,9-16,18-20H,2-3,8,17H2,1H3,(H,30,31)/b15-6+,26-14+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018394
PNG
(5,5-Bis-(3,4-dimethoxy-phenyl)-penta-2,4-dienoic a...)
Show SMILES [#6]-[#8]-c1ccc(cc1-[#8]-[#6])-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])c(-[#8]-[#6])c1
Show InChI InChI=1S/C31H36N2O5/c1-22(9-6-10-23-11-8-18-32-21-23)33-31(34)13-7-12-26(24-14-16-27(35-2)29(19-24)37-4)25-15-17-28(36-3)30(20-25)38-5/h7-8,11-22H,6,9-10H2,1-5H3,(H,33,34)/b13-7+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018324
PNG
(CHEMBL299760 | [1,1';2',1'']Terphenyl-4'-carboxyli...)
Show SMILES C[C@H](CCCc1cccnc1)NC(=O)c1ccc(-c2ccccc2)c(c1)-c1ccccc1
Show InChI InChI=1S/C29H28N2O/c1-22(10-8-11-23-12-9-19-30-21-23)31-29(32)26-17-18-27(24-13-4-2-5-14-24)28(20-26)25-15-6-3-7-16-25/h2-7,9,12-22H,8,10-11H2,1H3,(H,31,32)/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018320
PNG
(3',4'-Dimethoxy-2-propyl-biphenyl-4-carboxylic aci...)
Show SMILES CCCc1cc(ccc1-c1ccc(OC)c(OC)c1)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C28H34N2O3/c1-5-8-22-17-24(12-14-25(22)23-13-15-26(32-3)27(18-23)33-4)28(31)30-20(2)9-6-10-21-11-7-16-29-19-21/h7,11-20H,5-6,8-10H2,1-4H3,(H,30,31)/t20-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018354
PNG
(5-(4-Methoxy-phenyl)-octa-2,4-dienoic acid (1-meth...)
Show SMILES CCC\C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1
Show InChI InChI=1S/C25H32N2O2/c1-4-8-22(23-14-16-24(29-3)17-15-23)12-6-13-25(28)27-20(2)9-5-10-21-11-7-18-26-19-21/h6-7,11-20H,4-5,8-10H2,1-3H3,(H,27,28)/b13-6+,22-12+/t20-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018365
PNG
(6,6-Diphenyl-hexa-3,5-dienoic acid (4-pyridin-3-yl...)
Show SMILES O=[#6](-[#6]\[#6]=[#6]\[#6]=[#6](/c1ccccc1)-c1ccccc1)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1
Show InChI InChI=1S/C27H28N2O/c30-27(29-21-10-9-12-23-13-11-20-28-22-23)19-8-7-18-26(24-14-3-1-4-15-24)25-16-5-2-6-17-25/h1-8,11,13-18,20,22H,9-10,12,19,21H2,(H,29,30)/b8-7+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018348
PNG
(5,5-Bis-(3,4-dimethoxy-phenyl)-penta-2,4-dienoic a...)
Show SMILES [#6]-[#8]-c1ccc(cc1-[#8]-[#6])-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])c(-[#8]-[#6])c1
Show InChI InChI=1S/C30H34N2O5/c1-34-26-15-13-23(19-28(26)36-3)25(24-14-16-27(35-2)29(20-24)37-4)11-7-12-30(33)32-18-6-5-9-22-10-8-17-31-21-22/h7-8,10-17,19-21H,5-6,9,18H2,1-4H3,(H,32,33)/b12-7+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018329
PNG
(3',4'-Dimethoxy-biphenyl-4-carbothioic acid (1-met...)
Show SMILES COc1ccc(cc1OC)-c1ccc(cc1)C(=S)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C25H28N2O2S/c1-18(6-4-7-19-8-5-15-26-17-19)27-25(30)21-11-9-20(10-12-21)22-13-14-23(28-2)24(16-22)29-3/h5,8-18H,4,6-7H2,1-3H3,(H,27,30)/t18-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018386
PNG
(5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-c1cccnc1)-[#6]-1-[#6]-[#6]-1)\c1ccc(-[#8]-[#6])cc1
Show InChI InChI=1S/C31H34N2O3/c1-35-27-17-13-24(14-18-27)29(25-15-19-28(36-2)20-16-25)8-4-10-31(34)33-30(26-11-12-26)9-3-6-23-7-5-21-32-22-23/h4-5,7-8,10,13-22,26,30H,3,6,9,11-12H2,1-2H3,(H,33,34)/b10-4+/t30-/m0/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018362
PNG
(5,5-Di-p-tolyl-penta-2,4-dienoic acid (4-pyridin-3...)
Show SMILES [#6]-c1ccc(cc1)-[#6](=[#6]/[#6]=[#6]/[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#6])cc1
Show InChI InChI=1S/C28H30N2O/c1-22-11-15-25(16-12-22)27(26-17-13-23(2)14-18-26)9-5-10-28(31)30-20-4-3-7-24-8-6-19-29-21-24/h5-6,8-19,21H,3-4,7,20H2,1-2H3,(H,30,31)/b10-5+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018387
PNG
(5,5-Bis-(4-chloro-phenyl)-penta-2,4-dienoic acid (...)
Show SMILES Clc1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(Cl)cc1
Show InChI InChI=1S/C26H24Cl2N2O/c27-23-13-9-21(10-14-23)25(22-11-15-24(28)16-12-22)7-3-8-26(31)30-18-2-1-5-20-6-4-17-29-19-20/h3-4,6-17,19H,1-2,5,18H2,(H,30,31)/b8-3+
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PAF binding to dog platelets.


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018366
PNG
(5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid ...)
Show SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=[#6]\[#6]=[#6]\[#6](=O)-[#7]-[#6@H](-[#6])-[#6]-[#6]-[#6]-c1cccnc1)\c1ccc(-[#8]-[#6])cc1
Show InChI InChI=1S/C29H32N2O3/c1-22(7-4-8-23-9-6-20-30-21-23)31-29(32)11-5-10-28(24-12-16-26(33-2)17-13-24)25-14-18-27(34-3)19-15-25/h5-6,9-22H,4,7-8H2,1-3H3,(H,31,32)/b11-5+/t22-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand


J Med Chem 32: 1820-35 (1989)


BindingDB Entry DOI: 10.7270/Q2NZ86MR
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50018326
PNG
(2-Allyl-3',4'-dimethoxy-biphenyl-4-carboxylic acid...)
Show SMILES COc1ccc(cc1OC)-c1ccc(cc1CC=C)C(=O)N[C@H](C)CCCc1cccnc1
Show InChI InChI=1S/C28H32N2O3/c1-5-8-22-17-24(12-14-25(22)23-13-15-26(32-3)27(18-23)33-4)28(31)30-20(2)9-6-10-21-11-7-16-29-19-21/h5,7,11-20H,1,6,8-10H2,2-4H3,(H,30,31)/t20-/m1/s1
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Roche Research Center

Curated by ChEMBL


Assay Description
Inhibition of platelet activating factor receptor binding activity in dog platelets using [3H]-PAF as radioligand.


J Med Chem 32: 1814-20 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ8ZCJ
More data for this
Ligand-Target Pair
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