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Compile Data Set for Download or QSAR

Found 202 hits with Last Name = 'marzi' and Initial = 'm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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1.40n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015025
PNG
(CHEMBL3262408)
Show SMILES CN(CCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1
Show InChI InChI=1S/C24H29N3O/c1-25(21-9-5-10-22(28)19-21)13-6-14-26-15-17-27(18-16-26)24-12-4-8-20-7-2-3-11-23(20)24/h2-5,7-12,19,28H,6,13-18H2,1H3
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2.90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015219
PNG
(CHEMBL3262410)
Show SMILES Oc1cccc(CCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C20H26N2O/c23-20-11-6-8-18(17-20)7-4-5-12-21-13-15-22(16-14-21)19-9-2-1-3-10-19/h1-3,6,8-11,17,23H,4-5,7,12-16H2
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3.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015221
PNG
(CHEMBL3262395)
Show SMILES CCc1[nH]c2ccc(O)cc2c1CCN1CCN(CC1)c1cccc2ccccc12
Show InChI InChI=1S/C26H29N3O/c1-2-24-22(23-18-20(30)10-11-25(23)27-24)12-13-28-14-16-29(17-15-28)26-9-5-7-19-6-3-4-8-21(19)26/h3-11,18,27,30H,2,12-17H2,1H3
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6.60n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015197
PNG
(CHEMBL3262432)
Show SMILES Cl.CN(C(=O)CCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1
Show InChI InChI=1S/C27H33N3O2.ClH/c1-28(23-11-8-12-24(31)21-23)27(32)15-3-2-6-16-29-17-19-30(20-18-29)26-14-7-10-22-9-4-5-13-25(22)26;/h4-5,7-14,21,31H,2-3,6,15-20H2,1H3;1H
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8.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015197
PNG
(CHEMBL3262432)
Show SMILES Cl.CN(C(=O)CCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1
Show InChI InChI=1S/C27H33N3O2.ClH/c1-28(23-11-8-12-24(31)21-23)27(32)15-3-2-6-16-29-17-19-30(20-18-29)26-14-7-10-22-9-4-5-13-25(22)26;/h4-5,7-14,21,31H,2-3,6,15-20H2,1H3;1H
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8.10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015024
PNG
(CHEMBL3262411)
Show SMILES Oc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C19H25N3O/c23-19-9-4-6-17(16-19)20-10-5-11-21-12-14-22(15-13-21)18-7-2-1-3-8-18/h1-4,6-9,16,20,23H,5,10-15H2
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10n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015220
PNG
(CHEMBL3262393)
Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3cccc4ccccc34)c2c1
Show InChI InChI=1S/C24H25N3O/c28-20-8-9-23-22(16-20)19(17-25-23)10-11-26-12-14-27(15-13-26)24-7-3-5-18-4-1-2-6-21(18)24/h1-9,16-17,25,28H,10-15H2
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12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015015
PNG
(CHEMBL3262425)
Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H29N3O3S/c29-24-12-7-11-23(21-24)28(32(30,31)25-13-5-2-6-14-25)16-8-15-26-17-19-27(20-18-26)22-9-3-1-4-10-22/h1-7,9-14,21,29H,8,15-20H2
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12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015200
PNG
(CHEMBL3262430)
Show SMILES CN(CCCCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C23H33N3O/c1-24(22-12-9-13-23(27)20-22)14-7-2-3-8-15-25-16-18-26(19-17-25)21-10-5-4-6-11-21/h4-6,9-13,20,27H,2-3,7-8,14-19H2,1H3
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12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015220
PNG
(CHEMBL3262393)
Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3cccc4ccccc34)c2c1
Show InChI InChI=1S/C24H25N3O/c28-20-8-9-23-22(16-20)19(17-25-23)10-11-26-12-14-27(15-13-26)24-7-3-5-18-4-1-2-6-21(18)24/h1-9,16-17,25,28H,10-15H2
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12n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015033
PNG
(CHEMBL3262421)
Show SMILES O=Cc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C20H25N3O/c24-17-18-6-4-7-19(16-18)21-10-5-11-22-12-14-23(15-13-22)20-8-2-1-3-9-20/h1-4,6-9,16-17,21H,5,10-15H2
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13n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015222
PNG
(CHEMBL3262394)
Show SMILES Cc1[nH]c2ccc(O)cc2c1CCN1CCN(CC1)c1cccc2ccccc12
Show InChI InChI=1S/C25H27N3O/c1-18-21(23-17-20(29)9-10-24(23)26-18)11-12-27-13-15-28(16-14-27)25-8-4-6-19-5-2-3-7-22(19)25/h2-10,17,26,29H,11-16H2,1H3
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13n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015199
PNG
(CHEMBL3262429)
Show SMILES CN(CCCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C22H31N3O/c1-23(21-11-8-12-22(26)19-21)13-6-3-7-14-24-15-17-25(18-16-24)20-9-4-2-5-10-20/h2,4-5,8-12,19,26H,3,6-7,13-18H2,1H3
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17n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015027
PNG
(CHEMBL3262407)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C20H27N3O/c1-21(19-9-5-10-20(24)17-19)11-6-12-22-13-15-23(16-14-22)18-7-3-2-4-8-18/h2-5,7-10,17,24H,6,11-16H2,1H3
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20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015027
PNG
(CHEMBL3262407)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C20H27N3O/c1-21(19-9-5-10-20(24)17-19)11-6-12-22-13-15-23(16-14-22)18-7-3-2-4-8-18/h2-5,7-10,17,24H,6,11-16H2,1H3
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20n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015012
PNG
(CHEMBL3262422)
Show SMILES CCCN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C22H31N3O/c1-2-12-24(21-10-6-11-22(26)19-21)14-7-13-23-15-17-25(18-16-23)20-8-4-3-5-9-20/h3-6,8-11,19,26H,2,7,12-18H2,1H3
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21n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015198
PNG
(CHEMBL3262428)
Show SMILES CN(CCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C21H29N3O/c1-22(20-10-7-11-21(25)18-20)12-5-6-13-23-14-16-24(17-15-23)19-8-3-2-4-9-19/h2-4,7-11,18,25H,5-6,12-17H2,1H3
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30n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015211
PNG
(CHEMBL3259846)
Show SMILES Cl.CN(CCCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1
Show InChI InChI=1S/C27H35N3O.ClH/c1-28(24-12-9-13-25(31)22-24)16-6-2-3-7-17-29-18-20-30(21-19-29)27-15-8-11-23-10-4-5-14-26(23)27;/h4-5,8-15,22,31H,2-3,6-7,16-21H2,1H3;1H
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39n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015029
PNG
(CHEMBL3262417)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C21H30N4O2S/c1-23(21-11-6-8-19(18-21)22-28(2,26)27)12-7-13-24-14-16-25(17-15-24)20-9-4-3-5-10-20/h3-6,8-11,18,22H,7,12-17H2,1-2H3
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40n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015218
PNG
(CHEMBL3262406)
Show SMILES Cl.Oc1cccc(CCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C19H24N2O.ClH/c22-19-10-4-6-17(16-19)7-5-11-20-12-14-21(15-13-20)18-8-2-1-3-9-18;/h1-4,6,8-10,16,22H,5,7,11-15H2;1H
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40n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015019
PNG
(CHEMBL3262402)
Show SMILES Cl.CN(CCN1CCN(CC1)c1ccccc1)c1cccc(NS(C)(=O)=O)c1
Show InChI InChI=1S/C20H28N4O2S.ClH/c1-22(20-10-6-7-18(17-20)21-27(2,25)26)11-12-23-13-15-24(16-14-23)19-8-4-3-5-9-19;/h3-10,17,21H,11-16H2,1-2H3;1H
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57n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015030
PNG
(CHEMBL3262420)
Show SMILES NC(=O)c1cccc(NCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C20H26N4O/c21-20(25)17-6-4-7-18(16-17)22-10-5-11-23-12-14-24(15-13-23)19-8-2-1-3-9-19/h1-4,6-9,16,22H,5,10-15H2,(H2,21,25)
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63n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015223
PNG
(CHEMBL3262390)
Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C20H23N3O/c24-18-6-7-20-19(14-18)16(15-21-20)8-9-22-10-12-23(13-11-22)17-4-2-1-3-5-17/h1-7,14-15,21,24H,8-13H2
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63n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015223
PNG
(CHEMBL3262390)
Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3ccccc3)c2c1
Show InChI InChI=1S/C20H23N3O/c24-18-6-7-20-19(14-18)16(15-21-20)8-9-22-10-12-23(13-11-22)17-4-2-1-3-5-17/h1-7,14-15,21,24H,8-13H2
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63n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015031
PNG
(CHEMBL3262419)
Show SMILES COC(=O)c1cccc(NCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C21H27N3O2/c1-26-21(25)18-7-5-8-19(17-18)22-11-6-12-23-13-15-24(16-14-23)20-9-3-2-4-10-20/h2-5,7-10,17,22H,6,11-16H2,1H3
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78n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015016
PNG
(CHEMBL3262398)
Show SMILES Oc1cccc2CCC(Cc12)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C20H24N2O/c23-20-8-4-5-16-9-10-18(15-19(16)20)22-13-11-21(12-14-22)17-6-2-1-3-7-17/h1-8,18,23H,9-15H2
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81n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015020
PNG
(CHEMBL3262412)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(C)c1
Show InChI InChI=1S/C21H29N3/c1-19-8-6-11-21(18-19)22(2)12-7-13-23-14-16-24(17-15-23)20-9-4-3-5-10-20/h3-6,8-11,18H,7,12-17H2,1-2H3
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85n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015014
PNG
(CHEMBL3262423)
Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C25H29N3O/c29-25-14-7-13-24(21-25)28(23-11-5-2-6-12-23)16-8-15-26-17-19-27(20-18-26)22-9-3-1-4-10-22/h1-7,9-14,21,29H,8,15-20H2
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90n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015013
PNG
(CHEMBL3262424)
Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C26H31N3O/c30-26-14-7-13-25(21-26)29(22-23-9-3-1-4-10-23)16-8-15-27-17-19-28(20-18-27)24-11-5-2-6-12-24/h1-7,9-14,21,30H,8,15-20,22H2
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93n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015212
PNG
(CHEMBL3262433)
Show SMILES Cl.CN(CCCCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F)c1cccc(O)c1
Show InChI InChI=1S/C24H32F3N3O.ClH/c1-28(21-9-7-11-23(31)19-21)12-4-2-3-5-13-29-14-16-30(17-15-29)22-10-6-8-20(18-22)24(25,26)27;/h6-11,18-19,31H,2-5,12-17H2,1H3;1H
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96n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015032
PNG
(CHEMBL3262418)
Show SMILES OCc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C20H27N3O/c24-17-18-6-4-7-19(16-18)21-10-5-11-22-12-14-23(15-13-22)20-8-2-1-3-9-20/h1-4,6-9,16,21,24H,5,10-15,17H2
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109n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015023
PNG
(CHEMBL3262413)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(F)c1
Show InChI InChI=1S/C20H26FN3/c1-22(20-10-5-7-18(21)17-20)11-6-12-23-13-15-24(16-14-23)19-8-3-2-4-9-19/h2-5,7-10,17H,6,11-16H2,1H3
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112n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015215
PNG
(CHEMBL3262436)
Show SMILES Cl.Oc1cccc(c1)N(CCCCCCN1CCN(CC1)c1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C29H37N3O.ClH/c33-29-17-11-16-28(24-29)32(25-26-12-5-3-6-13-26)19-10-2-1-9-18-30-20-22-31(23-21-30)27-14-7-4-8-15-27;/h3-8,11-17,24,33H,1-2,9-10,18-23,25H2;1H
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138n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015021
PNG
(CHEMBL3262415)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(Br)c1
Show InChI InChI=1S/C20H26BrN3/c1-22(20-10-5-7-18(21)17-20)11-6-12-23-13-15-24(16-14-23)19-8-3-2-4-9-19/h2-5,7-10,17H,6,11-16H2,1H3
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161n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015028
PNG
(CHEMBL3262416)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(NC(C)=O)c1
Show InChI InChI=1S/C22H30N4O/c1-19(27)23-20-8-6-11-22(18-20)24(2)12-7-13-25-14-16-26(17-15-25)21-9-4-3-5-10-21/h3-6,8-11,18H,7,12-17H2,1-2H3,(H,23,27)
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161n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015017
PNG
(CHEMBL3262399)
Show SMILES CN(CCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C19H25N3O/c1-20(18-8-5-9-19(23)16-18)10-11-21-12-14-22(15-13-21)17-6-3-2-4-7-17/h2-9,16,23H,10-15H2,1H3
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161n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015022
PNG
(CHEMBL3262414)
Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(Cl)c1
Show InChI InChI=1S/C20H26ClN3/c1-22(20-10-5-7-18(21)17-20)11-6-12-23-13-15-24(16-14-23)19-8-3-2-4-9-19/h2-5,7-10,17H,6,11-16H2,1H3
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179n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015213
PNG
(CHEMBL3262435)
Show SMILES Cl.CCN(CCCCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C24H35N3O.ClH/c1-2-26(23-13-10-14-24(28)21-23)16-9-4-3-8-15-25-17-19-27(20-18-25)22-11-6-5-7-12-22;/h5-7,10-14,21,28H,2-4,8-9,15-20H2,1H3;1H
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191n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015201
PNG
(CHEMBL3262431)
Show SMILES Cl.CN(CCCCCCN1CCC(CC1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C24H34N2O.ClH/c1-25(23-12-9-13-24(27)20-23)16-7-2-3-8-17-26-18-14-22(15-19-26)21-10-5-4-6-11-21;/h4-6,9-13,20,22,27H,2-3,7-8,14-19H2,1H3;1H
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226n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015216
PNG
(CHEMBL3262426)
Show SMILES CN(CCCN1CCC(CC1)(c1ccccc1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C27H32N2O/c1-28(25-14-8-15-26(30)22-25)18-9-19-29-20-16-27(17-21-29,23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-8,10-15,22,30H,9,16-21H2,1H3
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242n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015018
PNG
(CHEMBL3262404)
Show SMILES Oc1cccc(NCCN2CCN(CC2)c2ccccc2)c1
Show InChI InChI=1S/C18H23N3O/c22-18-8-4-5-16(15-18)19-9-10-20-11-13-21(14-12-20)17-6-2-1-3-7-17/h1-8,15,19,22H,9-14H2
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252n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015217
PNG
(CHEMBL3262427)
Show SMILES CN(CCCN1CCC(CC1)N(c1ccccc1)c1ccccc1)c1cccc(O)c1
Show InChI InChI=1S/C27H33N3O/c1-28(26-14-8-15-27(31)22-26)18-9-19-29-20-16-25(17-21-29)30(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-8,10-15,22,25,31H,9,16-21H2,1H3
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310n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015224
PNG
(CHEMBL3262401)
Show SMILES Cl.CN(CCN1CCN(CC1)c1ccccc1)c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C19H24N4O2.ClH/c1-20(18-8-5-9-19(16-18)23(24)25)10-11-21-12-14-22(15-13-21)17-6-3-2-4-7-17;/h2-9,16H,10-15H2,1H3;1H
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332n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50015026
PNG
(CHEMBL3262409)
Show SMILES CN(CCCN1CCN(CC1)c1ccc2ccccc2c1)c1cccc(O)c1
Show InChI InChI=1S/C24H29N3O/c1-25(22-8-4-9-24(28)19-22)12-5-13-26-14-16-27(17-15-26)23-11-10-20-6-2-3-7-21(20)18-23/h2-4,6-11,18-19,28H,5,12-17H2,1H3
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434n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Urbino

Curated by ChEMBL


Assay Description
Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis


Eur J Med Chem 80: 8-35 (2014)


Article DOI: 10.1016/j.ejmech.2014.04.034
BindingDB Entry DOI: 10.7270/Q2HT2QV6
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))
BDBM19130
PNG
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1|
Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)
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n/an/a 0.400n/an/an/an/an/an/a



R&D Sigma-Tau SpA

Curated by ChEMBL


Assay Description
Inhibition of human HDAC6


Bioorg Med Chem Lett 19: 2346-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.029
BindingDB Entry DOI: 10.7270/Q2154GX2
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))
BDBM50297445
PNG
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12
Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29)
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n/an/a 2.60n/an/an/an/an/an/a



Sigma-Tau Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human HDAC6 by fluroimetry


Bioorg Med Chem Lett 19: 2840-3 (2009)

Checked by Author
Article DOI: 10.1016/j.bmcl.2009.03.101
BindingDB Entry DOI: 10.7270/Q2PN95PT
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))
BDBM50297444
PNG
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)
Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27)
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n/an/a 6n/an/an/an/an/an/a



Sigma-Tau Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human HDAC6 by fluroimetry


Bioorg Med Chem Lett 19: 2840-3 (2009)

Checked by Author
Article DOI: 10.1016/j.bmcl.2009.03.101
BindingDB Entry DOI: 10.7270/Q2PN95PT
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))
BDBM19130
PNG
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1|
Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)
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n/an/a 7n/an/an/an/an/an/a



R&D Sigma-Tau SpA

Curated by ChEMBL


Assay Description
Inhibition of human HDAC1


Bioorg Med Chem Lett 19: 2346-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.029
BindingDB Entry DOI: 10.7270/Q2154GX2
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))
BDBM19130
PNG
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1|
Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)
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n/an/a 10n/an/an/an/an/an/a



R&D Sigma-Tau SpA

Curated by ChEMBL


Assay Description
Inhibition of human HDAC3


Bioorg Med Chem Lett 19: 2346-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.029
BindingDB Entry DOI: 10.7270/Q2154GX2
More data for this
Ligand-Target Pair
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