Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Homo sapiens (Human)) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Curated by ChEMBL | Bioorg Med Chem Lett 27: 1840-1847 (2017) Article DOI: 10.1016/j.bmcl.2017.02.037 BindingDB Entry DOI: 10.7270/Q2M047Q1 | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Genome polyprotein (Hepatitis C virus (HCV)) | BDBM139221![]() (US8877733, 28) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 7.5 | 35 |
Gilead Sciences, Inc. US Patent | Assay Description Assay Protocol: Either wild type or S282T (Migliaccio, et al., J. Biol. Chem. 2003, 49164-49170; Klumpp, et al., J. Biol. Chem. 2006, 3793-3799) muta... | US Patent US8877733 (2014) BindingDB Entry DOI: 10.7270/Q2QC026F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus (HCV)) | BDBM139220![]() (US8877733, 27) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.5 | 35 |
Gilead Sciences, Inc. US Patent | Assay Description Assay Protocol: Either wild type or S282T (Migliaccio, et al., J. Biol. Chem. 2003, 49164-49170; Klumpp, et al., J. Biol. Chem. 2006, 3793-3799) muta... | US Patent US8877733 (2014) BindingDB Entry DOI: 10.7270/Q2QC026F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Homo sapiens (Human)) | BDBM50237537![]() (CHEMBL4093601) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences Curated by ChEMBL | Bioorg Med Chem Lett 27: 1840-1847 (2017) Article DOI: 10.1016/j.bmcl.2017.02.037 BindingDB Entry DOI: 10.7270/Q2M047Q1 | ||||||||||||
More data for this Ligand-Target Pair |