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Compile Data Set for Download or QSAR

Found 183 hits with Last Name = 'moinet' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM50103430
PNG
(6-Amino-2-(3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihy...)
Show SMILES C[C@H]([C@@H](NC(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)N[C@@H](CCCCN)C(=O)OC(C)(C)C)c1c[nH]c2ccccc12
Show InChI InChI=1S/C35H47N7O5/c1-22(25-21-37-26-12-6-5-11-24(25)26)30(31(43)38-28(14-9-10-18-36)32(44)47-35(2,3)4)40-33(45)41-19-16-23(17-20-41)42-29-15-8-7-13-27(29)39-34(42)46/h5-8,11-13,15,21-23,28,30,37H,9-10,14,16-20,36H2,1-4H3,(H,38,43)(H,39,46)(H,40,45)/t22-,28-,30+/m0/s1
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0.0100n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing each of the cloned human SRIF receptor (sst-2) subtypes


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 2


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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0.0490n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst2 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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0.140n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst5 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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0.140n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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0.360n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst1 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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0.590n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst4 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50369890
PNG
(CHEMBL1237140 | CHEMBL1788167)
Show SMILES CCCCC1(CCCC)N[C@@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r|
Show InChI InChI=1S/C28H34N4/c1-3-5-16-28(17-6-4-2)26-22(21-14-10-11-15-23(21)30-26)18-24(32-28)27-29-19-25(31-27)20-12-8-7-9-13-20/h7-15,19,24,30,32H,3-6,16-18H2,1-2H3,(H,29,31)/t24-/m0/s1
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0.790n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103414
PNG
(1-Cyclohexyl-1-methyl-3-(4-phenyl-1H-imidazol-2-yl...)
Show SMILES CC1(NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1)C1CCCCC1
Show InChI InChI=1S/C27H30N4/c1-27(19-12-6-3-7-13-19)25-21(20-14-8-9-15-22(20)29-25)16-23(31-27)26-28-17-24(30-26)18-10-4-2-5-11-18/h2,4-5,8-11,14-15,17,19,23,29,31H,3,6-7,12-13,16H2,1H3,(H,28,30)
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0.900n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103417
PNG
(1,1-Dipentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9...)
Show SMILES CCCCCC1(CCCCC)NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C30H38N4/c1-3-5-12-18-30(19-13-6-4-2)28-24(23-16-10-11-17-25(23)32-28)20-26(34-30)29-31-21-27(33-29)22-14-8-7-9-15-22/h7-11,14-17,21,26,32,34H,3-6,12-13,18-20H2,1-2H3,(H,31,33)
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0.920n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50369893
PNG
(CHEMBL1201959)
Show SMILES C1CCC(CC1)C1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C26H28N4/c1-3-9-17(10-4-1)23-16-27-26(30-23)22-15-20-19-13-7-8-14-21(19)28-25(20)24(29-22)18-11-5-2-6-12-18/h1,3-4,7-10,13-14,16,18,22,24,28-29H,2,5-6,11-12,15H2,(H,27,30)
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1.70n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50369890
PNG
(CHEMBL1237140 | CHEMBL1788167)
Show SMILES CCCCC1(CCCC)N[C@@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |r|
Show InChI InChI=1S/C28H34N4/c1-3-5-16-28(17-6-4-2)26-22(21-14-10-11-15-23(21)30-26)18-24(32-28)27-29-19-25(31-27)20-12-8-7-9-13-20/h7-15,19,24,30,32H,3-6,16-18H2,1-2H3,(H,29,31)/t24-/m0/s1
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3.40n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103421
PNG
(1,1-Dibutyl-6-chloro-3-(4-phenyl-1H-imidazol-2-yl)...)
Show SMILES CCCCC1(CCCC)NC(Cc2c1[nH]c1ccc(Cl)cc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C28H33ClN4/c1-3-5-14-28(15-6-4-2)26-22(21-16-20(29)12-13-23(21)31-26)17-24(33-28)27-30-18-25(32-27)19-10-8-7-9-11-19/h7-13,16,18,24,31,33H,3-6,14-15,17H2,1-2H3,(H,30,32)
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3.40n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 4


(Homo sapiens (Human))
BDBM50068039
PNG
(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)
Show SMILES Clc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Show InChI InChI=1S/C22H25BrCl2N6S/c23-17-5-7-21(29-12-17)31(14-16-4-6-19(24)20(25)11-16)10-2-9-28-22(32)27-8-1-3-18-13-26-15-30-18/h4-7,11-13,15H,1-3,8-10,14H2,(H,26,30)(H2,27,28,32)
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6n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-4) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103425
PNG
(6-Methyl-1,1-dipentyl-3-(4-phenyl-1H-imidazol-2-yl...)
Show SMILES CCCCCC1(CCCCC)NC(Cc2c1[nH]c1ccc(C)cc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C31H40N4/c1-4-6-11-17-31(18-12-7-5-2)29-25(24-19-22(3)15-16-26(24)33-29)20-27(35-31)30-32-21-28(34-30)23-13-9-8-10-14-23/h8-10,13-16,19,21,27,33,35H,4-7,11-12,17-18,20H2,1-3H3,(H,32,34)
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6.90n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103433
PNG
(1,1-Diethyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-...)
Show SMILES CCC1(CC)NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C24H26N4/c1-3-24(4-2)22-18(17-12-8-9-13-19(17)26-22)14-20(28-24)23-25-15-21(27-23)16-10-6-5-7-11-16/h5-13,15,20,26,28H,3-4,14H2,1-2H3,(H,25,27)
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11n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103432
PNG
(1-Pentyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-tet...)
Show SMILES CCCCCC1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C25H28N4/c1-2-3-5-14-21-24-19(18-12-8-9-13-20(18)28-24)15-22(27-21)25-26-16-23(29-25)17-10-6-4-7-11-17/h4,6-13,16,21-22,27-28H,2-3,5,14-15H2,1H3,(H,26,29)
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11n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103415
PNG
(3-(4-phenyl-1H-2-imidazolyl)-(3S)-spiro[2,3,4,9-te...)
Show SMILES C1c2ccccc2CC11NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C28H24N4/c1-2-8-18(9-3-1)25-17-29-27(31-25)24-14-22-21-12-6-7-13-23(21)30-26(22)28(32-24)15-19-10-4-5-11-20(19)16-28/h1-13,17,24,30,32H,14-16H2,(H,29,31)
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13n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103420
PNG
(6-Benzyloxy-1,1-dibutyl-3-(4-phenyl-1H-imidazol-2-...)
Show SMILES CCCCC1(CCCC)NC(Cc2c1[nH]c1ccc(OCc3ccccc3)cc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C35H40N4O/c1-3-5-19-35(20-6-4-2)33-29(22-31(39-35)34-36-23-32(38-34)26-15-11-8-12-16-26)28-21-27(17-18-30(28)37-33)40-24-25-13-9-7-10-14-25/h7-18,21,23,31,37,39H,3-6,19-20,22,24H2,1-2H3,(H,36,38)
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17n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103427
PNG
(1,1-Dihexyl-3-(4-phenyl-1H-imidazol-2-yl)-2,3,4,9-...)
Show SMILES CCCCCCC1(CCCCCC)NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C32H42N4/c1-3-5-7-14-20-32(21-15-8-6-4-2)30-26(25-18-12-13-19-27(25)34-30)22-28(36-32)31-33-23-29(35-31)24-16-10-9-11-17-24/h9-13,16-19,23,28,34,36H,3-8,14-15,20-22H2,1-2H3,(H,33,35)
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28n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103429
PNG
(CHEMBL321066 | Dimethyl-{4-[3-(4-phenyl-1H-imidazo...)
Show SMILES CN(C)c1ccc(cc1)C1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C28H27N5/c1-33(2)20-14-12-19(13-15-20)26-27-22(21-10-6-7-11-23(21)30-27)16-24(31-26)28-29-17-25(32-28)18-8-4-3-5-9-18/h3-15,17,24,26,30-31H,16H2,1-2H3,(H,29,32)
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33n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099179
PNG
(CHEMBL368334 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES COc1ccc(cc1)C(N)=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1 |w:8.9|
Show InChI InChI=1S/C27H25N5O/c1-33-21-13-11-19(12-14-21)26(28)31-24(15-20-16-29-23-10-6-5-9-22(20)23)27-30-17-25(32-27)18-7-3-2-4-8-18/h2-14,16-17,24,29H,15H2,1H3,(H2,28,31)(H,30,32)/t24-/m1/s1
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36n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103424
PNG
(1-(4-Methoxy-phenyl)-3-(4-phenyl-1H-imidazol-2-yl)...)
Show SMILES COc1ccc(cc1)C1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C27H24N4O/c1-32-19-13-11-18(12-14-19)25-26-21(20-9-5-6-10-22(20)29-26)15-23(30-25)27-28-16-24(31-27)17-7-3-2-4-8-17/h2-14,16,23,25,29-30H,15H2,1H3,(H,28,31)
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60n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099174
PNG
(4-Chloro-N-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-1H-i...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C26H22ClN5/c27-20-12-10-18(11-13-20)25(28)31-23(14-19-15-29-22-9-5-4-8-21(19)22)26-30-16-24(32-26)17-6-2-1-3-7-17/h1-13,15-16,23,29H,14H2,(H2,28,31)(H,30,32)/t23-/m1/s1
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79n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50369894
PNG
(CHEMBL1202953)
Show SMILES C1C2CC3CC1CC(C2)C31NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1 |TLB:4:3:0.5.6:8,10:9:2:0.4.5,14:9:2:0.4.5,14:9:0.5.6:8,THB:4:5:8:2.3.9,6:5:2:7.8.9,6:7:2:0.4.5,9:3:0:6.7.8,9:7:0:2.3.4,10:9:0.5.6:8,(1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,;1.33,-.77,;1.33,.77,;1.73,1.42,;,1.54,;.72,2.96,;-.05,4.29,;-1.59,4.29,;-2.36,2.96,;-1.59,1.62,;-2.62,.48,;-4.02,1.1,;-5.43,.48,;-6.67,1.38,;-6.51,2.91,;-5.11,3.54,;-3.86,2.63,;.72,5.62,;2.24,5.77,;2.56,7.27,;1.23,8.04,;.08,7.01,;3.97,7.9,;5.27,7.1,;6.63,7.83,;6.67,9.37,;5.36,10.18,;4.01,9.44,)|
Show InChI InChI=1S/C29H30N4/c1-2-6-19(7-3-1)26-16-30-28(32-26)25-15-23-22-8-4-5-9-24(22)31-27(23)29(33-25)20-11-17-10-18(13-20)14-21(29)12-17/h1-9,16-18,20-21,25,31,33H,10-15H2,(H,30,32)
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84n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM81767
PNG
(15-28-Somatostatin-28 | CAS_38916-34-6 | CB6417646...)
Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N)[C@@H](C)O |r|
Show InChI InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
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120n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL




Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099172
PNG
(1-(2,4-Difluoro-phenyl)-3-[(R)-2-(1H-indol-3-yl)-1...)
Show SMILES Fc1ccc(NC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c(F)c1
Show InChI InChI=1S/C26H21F2N5O/c27-18-10-11-22(20(28)13-18)32-26(34)33-23(12-17-14-29-21-9-5-4-8-19(17)21)25-30-15-24(31-25)16-6-2-1-3-7-16/h1-11,13-15,23,29H,12H2,(H,30,31)(H2,32,33,34)/t23-/m1/s1
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170n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103419
PNG
(1-(2-Nitro-phenyl)-3-(4-phenyl-1H-imidazol-2-yl)-2...)
Show SMILES [O-][N+](=O)c1ccccc1C1NC(Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C26H21N5O2/c32-31(33)23-13-7-5-11-18(23)24-25-19(17-10-4-6-12-20(17)28-25)14-21(29-24)26-27-15-22(30-26)16-8-2-1-3-9-16/h1-13,15,21,24,28-29H,14H2,(H,27,30)
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200n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099173
PNG
(2,4-Difluoro-N-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(F)cc1F |w:1.0|
Show InChI InChI=1S/C26H21F2N5/c27-18-10-11-20(21(28)13-18)25(29)32-23(12-17-14-30-22-9-5-4-8-19(17)22)26-31-15-24(33-26)16-6-2-1-3-7-16/h1-11,13-15,23,30H,12H2,(H2,29,32)(H,31,33)/t23-/m1/s1
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200n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099175
PNG
(CHEMBL175356 | [(R)-2-(1H-Indol-3-yl)-1-(4-phenyl-...)
Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C24H26N4O2/c1-24(2,3)30-23(29)28-20(13-17-14-25-19-12-8-7-11-18(17)19)22-26-15-21(27-22)16-9-5-4-6-10-16/h4-12,14-15,20,25H,13H2,1-3H3,(H,26,27)(H,28,29)/t20-/m1/s1
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210n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099170
PNG
(CHEMBL368993 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES FC(F)(F)c1cccc(CC(=O)N[C@H](Cc2c[nH]c3ccccc23)c2nc(c[nH]2)-c2ccccc2)c1
Show InChI InChI=1S/C28H23F3N4O/c29-28(30,31)21-10-6-7-18(13-21)14-26(36)34-24(15-20-16-32-23-12-5-4-11-22(20)23)27-33-17-25(35-27)19-8-2-1-3-9-19/h1-13,16-17,24,32H,14-15H2,(H,33,35)(H,34,36)/t24-/m1/s1
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240n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099182
PNG
(CHEMBL174872 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccccc1 |w:1.0|
Show InChI InChI=1S/C26H23N5/c27-25(19-11-5-2-6-12-19)30-23(15-20-16-28-22-14-8-7-13-21(20)22)26-29-17-24(31-26)18-9-3-1-4-10-18/h1-14,16-17,23,28H,15H2,(H2,27,30)(H,29,31)/t23-/m1/s1
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250n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103426
PNG
(3-(4-Phenyl-1H-imidazol-2-yl)-1-pyridin-4-yl-2,3,4...)
Show SMILES C1C(NC(c2[nH]c3ccccc3c12)c1ccncc1)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C25H21N5/c1-2-6-16(7-3-1)22-15-27-25(30-22)21-14-19-18-8-4-5-9-20(18)28-24(19)23(29-21)17-10-12-26-13-11-17/h1-13,15,21,23,28-29H,14H2,(H,27,30)
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320n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50097789
PNG
(2-[8-(3-Amino-propyl)-6-benzo[b]thiophen-3-yl-imid...)
Show SMILES CC(C)(C(=O)NC1CCCCC1)c1cn2cc(nc(CCCN)c2n1)-c1csc2ccccc12
Show InChI InChI=1S/C27H33N5OS/c1-27(2,26(33)29-18-9-4-3-5-10-18)24-16-32-15-22(30-21(12-8-14-28)25(32)31-24)20-17-34-23-13-7-6-11-19(20)23/h6-7,11,13,15-18H,3-5,8-10,12,14,28H2,1-2H3,(H,29,33)
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360n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL




Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099180
PNG
(1-tert-Butyl-3-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-...)
Show SMILES CC(C)(C)NC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C24H27N5O/c1-24(2,3)29-23(30)28-20(13-17-14-25-19-12-8-7-11-18(17)19)22-26-15-21(27-22)16-9-5-4-6-10-16/h4-12,14-15,20,25H,13H2,1-3H3,(H,26,27)(H2,28,29,30)/t20-/m1/s1
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400n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099176
PNG
(CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(OC(F)(F)F)cc1 |w:1.0|
Show InChI InChI=1S/C27H22F3N5O/c28-27(29,30)36-20-12-10-18(11-13-20)25(31)34-23(14-19-15-32-22-9-5-4-8-21(19)22)26-33-16-24(35-26)17-6-2-1-3-7-17/h1-13,15-16,23,32H,14H2,(H2,31,34)(H,33,35)/t23-/m1/s1
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410n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50097781
PNG
(3-[6-(3-Nitro-phenyl)-2-phenyl-imidazo[1,2-a]pyraz...)
Show SMILES NCCCc1nc(cn2cc(nc12)-c1ccccc1)-c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C21H19N5O2/c22-11-5-10-18-21-24-19(15-6-2-1-3-7-15)13-25(21)14-20(23-18)16-8-4-9-17(12-16)26(27)28/h1-4,6-9,12-14H,5,10-11,22H2
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430n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory constant on human somatostatin receptor 5


Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103428
PNG
(1,1-Dibutyl-3-(4-phenyl-1H-imidazol-2-yl)-1,2,3,4-...)
Show SMILES CCCCC1(CCCC)N[C@H](Cc2c1sc1ccccc21)c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C28H33N3S/c1-3-5-16-28(17-6-4-2)26-22(21-14-10-11-15-25(21)32-26)18-23(31-28)27-29-19-24(30-27)20-12-8-7-9-13-20/h7-15,19,23,31H,3-6,16-18H2,1-2H3,(H,29,30)/t23-/m1/s1
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430n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099178
PNG
(CHEMBL367699 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(cc1)C(F)(F)F |w:1.0|
Show InChI InChI=1S/C27H22F3N5/c28-27(29,30)20-12-10-18(11-13-20)25(31)34-23(14-19-15-32-22-9-5-4-8-21(19)22)26-33-16-24(35-26)17-6-2-1-3-7-17/h1-13,15-16,23,32H,14H2,(H2,31,34)(H,33,35)/t23-/m1/s1
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500n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50097784
PNG
(2-[8-(3-Amino-propyl)-6-benzo[b]thiophen-3-yl-imid...)
Show SMILES CCCCNC(=O)C(C)(C)c1cn2cc(nc(CCCN)c2n1)-c1csc2ccccc12
Show InChI InChI=1S/C25H31N5OS/c1-4-5-13-27-24(31)25(2,3)22-15-30-14-20(28-19(10-8-12-26)23(30)29-22)18-16-32-21-11-7-6-9-17(18)21/h6-7,9,11,14-16H,4-5,8,10,12-13,26H2,1-3H3,(H,27,31)
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540n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory constant on human somatostatin receptor 5


Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50097782
PNG
(3-(6-Benzo[b]thiophen-3-yl-2-phenyl-imidazo[1,2-a]...)
Show SMILES NCCCc1nc(cn2cc(nc12)-c1ccccc1)-c1csc2ccccc12
Show InChI InChI=1S/C23H20N4S/c24-12-6-10-19-23-26-20(16-7-2-1-3-8-16)13-27(23)14-21(25-19)18-15-28-22-11-5-4-9-17(18)22/h1-5,7-9,11,13-15H,6,10,12,24H2
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600n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibitory constant on human somatostatin receptor 5


Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50099174
PNG
(4-Chloro-N-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-1H-i...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(Cl)cc1 |w:1.0|
Show InChI InChI=1S/C26H22ClN5/c27-20-12-10-18(11-13-20)25(28)31-23(14-19-15-29-22-9-5-4-8-21(19)22)26-30-16-24(32-26)17-6-2-1-3-7-17/h1-13,15-16,23,29H,14H2,(H2,28,31)(H,30,32)/t23-/m1/s1
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691n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst5 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099177
PNG
(CHEMBL174490 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES CC(N)=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1 |w:1.1|
Show InChI InChI=1S/C21H21N5/c1-14(22)25-19(11-16-12-23-18-10-6-5-9-17(16)18)21-24-13-20(26-21)15-7-3-2-4-8-15/h2-10,12-13,19,23H,11H2,1H3,(H2,22,25)(H,24,26)/t19-/m1/s1
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700n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50103434
PNG
(1-Cyclohexyl-3-(4-phenyl-1H-imidazol-2-yl)-9H-beta...)
Show SMILES C1CCC(CC1)c1nc(cc2c3ccccc3[nH]c12)-c1nc(c[nH]1)-c1ccccc1
Show InChI InChI=1S/C26H24N4/c1-3-9-17(10-4-1)23-16-27-26(30-23)22-15-20-19-13-7-8-14-21(19)28-25(20)24(29-22)18-11-5-2-6-12-18/h1,3-4,7-10,13-16,18,28H,2,5-6,11-12H2,(H,27,30)
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750n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of [125 I -Tyr]SRIF-14 binding to membranes isolated from CHO-K1 cells expressing cloned human SRIF receptor (sst-3) subtype


J Med Chem 44: 2990-3000 (2001)


BindingDB Entry DOI: 10.7270/Q2DB82JT
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50219320
PNG
(CHEMBL2112935)
Show SMILES NCCCc1nc(cn2cc(nc12)-c1ccccc1)-c1c[nH]c2ccccc12
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790n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL




Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50099176
PNG
(CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(OC(F)(F)F)cc1 |w:1.0|
Show InChI InChI=1S/C27H22F3N5O/c28-27(29,30)36-20-12-10-18(11-13-20)25(31)34-23(14-19-15-32-22-9-5-4-8-21(19)22)26-33-16-24(35-26)17-6-2-1-3-7-17/h1-13,15-16,23,32H,14H2,(H2,31,34)(H,33,35)/t23-/m1/s1
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1.13E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst5 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50099177
PNG
(CHEMBL174490 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...)
Show SMILES CC(N)=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1 |w:1.1|
Show InChI InChI=1S/C21H21N5/c1-14(22)25-19(11-16-12-23-18-10-6-5-9-17(16)18)21-24-13-20(26-21)15-7-3-2-4-8-15/h2-10,12-13,19,23H,11H2,1H3,(H2,22,25)(H,24,26)/t19-/m1/s1
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1.19E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst5 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 5


(Homo sapiens (Human))
BDBM50219321
PNG
(CHEMBL2112934)
Show SMILES CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1
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1.20E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL




Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50219321
PNG
(CHEMBL2112934)
Show SMILES CC(C)(C(=O)NCCc1c[nH]c2ccccc12)c1cn2cc(Cc3ccccc3)nc(CCCN)c2n1
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1.20E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL




Bioorg Med Chem Lett 11: 741-5 (2001)


BindingDB Entry DOI: 10.7270/Q2Z3205B
More data for this
Ligand-Target Pair
Somatostatin receptor type 3


(Homo sapiens (Human))
BDBM50099169
PNG
(4-tert-Butyl-N-[(R)-2-(1H-indol-3-yl)-1-(4-phenyl-...)
Show SMILES CC(C)(C)c1ccc(cc1)C(N)=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1 |w:10.11|
Show InChI InChI=1S/C30H31N5/c1-30(2,3)23-15-13-21(14-16-23)28(31)34-26(17-22-18-32-25-12-8-7-11-24(22)25)29-33-19-27(35-29)20-9-5-4-6-10-20/h4-16,18-19,26,32H,17H2,1-3H3,(H2,31,34)(H,33,35)/t26-/m1/s1
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1.40E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst3 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
Somatostatin receptor type 1


(Homo sapiens (Human))
BDBM50099181
PNG
(CHEMBL177337 | [(R)-2-(1H-Indol-3-yl)-1-(4-phenyl-...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)OCc1ccccc1
Show InChI InChI=1S/C27H24N4O2/c32-27(33-18-19-9-3-1-4-10-19)31-24(15-21-16-28-23-14-8-7-13-22(21)23)26-29-17-25(30-26)20-11-5-2-6-12-20/h1-14,16-17,24,28H,15,18H2,(H,29,30)(H,31,32)/t24-/m1/s1
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1.40E+3n/an/an/an/an/an/an/an/a



Institut Henri Beaufour

Curated by ChEMBL


Assay Description
Inhibition of human sst1 receptor expressed in CHO cells


Bioorg Med Chem Lett 11: 991-5 (2001)


BindingDB Entry DOI: 10.7270/Q2D50NHN
More data for this
Ligand-Target Pair
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