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Compile Data Set for Download or QSAR

Found 1052 hits with Last Name = 'nakagawa' and Initial = 't'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 3A


(Homo sapiens (Human))
BDBM50351401
PNG
(CHEMBL1819091)
Show SMILES CC[C@@]1(N)CCCN(C1)c1cc2n(C)c(=O)n(C)c(=O)c2n1Cc1cc(F)ccc1C#N |r|
Show InChI InChI=1S/C23H27FN6O2/c1-4-23(26)8-5-9-29(14-23)19-11-18-20(21(31)28(3)22(32)27(18)2)30(19)13-16-10-17(24)7-6-15(16)12-25/h6-7,10-11H,4-5,8-9,13-14,26H2,1-3H3/t23-/m1/s1
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0.0220n/an/an/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysis


Bioorg Med Chem 19: 5490-9 (2011)


Article DOI: 10.1016/j.bmc.2011.07.042
BindingDB Entry DOI: 10.7270/Q2T72HT6
More data for this
Ligand-Target Pair
Cytochrome P450 3A


(Homo sapiens (Human))
BDBM50351399
PNG
(CHEMBL1819089)
Show SMILES Cn1c2cc(N3CCC[C@@H](N)C3)n(Cc3cc(F)ccc3C#N)c2c(=O)n(C)c1=O |r|
Show InChI InChI=1S/C21H23FN6O2/c1-25-17-9-18(27-7-3-4-16(24)12-27)28(19(17)20(29)26(2)21(25)30)11-14-8-15(22)6-5-13(14)10-23/h5-6,8-9,16H,3-4,7,11-12,24H2,1-2H3/t16-/m1/s1
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0.0260n/an/an/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysis


Bioorg Med Chem 19: 5490-9 (2011)


Article DOI: 10.1016/j.bmc.2011.07.042
BindingDB Entry DOI: 10.7270/Q2T72HT6
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50247054
PNG
(6-(3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azep...)
Show SMILES CNC(=O)c1ccc(Oc2ccc3CCN(CCc3c2)C2CCC2)nc1
Show InChI InChI=1S/C21H25N3O2/c1-22-21(25)17-6-8-20(23-14-17)26-19-7-5-15-9-11-24(18-3-2-4-18)12-10-16(15)13-19/h5-8,13-14,18H,2-4,9-12H2,1H3,(H,22,25)
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0.120n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to histamine H3 receptor


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158073
PNG
(US9024044, 1 | US9227949, 1 | US9655879, 1)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 |r|
Show InChI InChI=1/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/s2
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0.140n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158073
PNG
(US9024044, 1 | US9227949, 1 | US9655879, 1)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 |r|
Show InChI InChI=1/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/s2
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0.140n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158073
PNG
(US9024044, 1 | US9227949, 1 | US9655879, 1)
Show SMILES NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 |r|
Show InChI InChI=1/C22H22FN3O7S/c23-13-8-11(18(24)25)2-4-15(13)33-20(31)16-5-3-12(34-16)10-22(6-1-7-22)21(32)26-14(19(29)30)9-17(27)28/h2-5,8,14H,1,6-7,9-10H2,(H3,24,25)(H,26,32)(H,27,28)(H,29,30)/t14-/s2
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0.140n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50247053
PNG
(1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...)
Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1
Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2
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0.160n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in HEK293 cells by [35S]gammaS binding assay


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158146
PNG
(US9024044, 74 | US9227949, 74 | US9655879, 74)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31)
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0.180n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158146
PNG
(US9024044, 74 | US9227949, 74 | US9655879, 74)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31)
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0.180n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158146
PNG
(US9024044, 74 | US9227949, 74 | US9655879, 74)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(O)cc(c1)C(O)=O
Show InChI InChI=1S/C24H21FN3O6S/c1-24(2,23(33)28-14-7-13(21(30)31)8-15(29)10-14)11-16-4-6-19(35-16)22(32)34-18-5-3-12(20(26)27)9-17(18)25/h3-10H,11H2,1-2H3,(H3,26,27)(H,28,33)(H,30,31)
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0.180n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50268293
PNG
((5-(1-cyclobutylpiperidin-4-yloxy)-1-(2,2,2-triflu...)
Show SMILES FC(F)(F)Cn1c(cc2cc(OC3CCN(CC3)C3CCC3)ccc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C24H30F3N3O3/c25-24(26,27)16-30-21-5-4-20(33-19-6-8-28(9-7-19)18-2-1-3-18)14-17(21)15-22(30)23(31)29-10-12-32-13-11-29/h4-5,14-15,18-19H,1-3,6-13,16H2
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0.200n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.210n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.210n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.210n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158077
PNG
(US9024044, 5 | US9227949, 5 | US9655879, 5)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O
Show InChI InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28)
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0.240n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.240n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308550
PNG
(US9655879, 86)
Show SMILES Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1nn[nH]n1)C(O)=O |r|
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0.240n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158077
PNG
(US9024044, 5 | US9227949, 5 | US9655879, 5)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O
Show InChI InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28)
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0.240n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM199976
PNG
(US9227949, 86)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](Cc1nn[nH]n1)C(O)=O |r|
Show InChI InChI=1/C23H26FN7O5S/c1-3-23(4-2,22(35)27-15(20(32)33)10-18-28-30-31-29-18)11-13-6-8-17(37-13)21(34)36-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,35)(H,32,33)(H,28,29,30,31)/t15-/s2
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0.240n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158077
PNG
(US9024044, 5 | US9227949, 5 | US9655879, 5)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N(CC=C)CC(O)=O
Show InChI InChI=1S/C22H24FN3O5S/c1-4-9-26(12-18(27)28)21(30)22(2,3)11-14-6-8-17(32-14)20(29)31-16-7-5-13(19(24)25)10-15(16)23/h4-8,10H,1,9,11-12H2,2-3H3,(H3,24,25)(H,27,28)
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0.240n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.240n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158140
PNG
(US9024044, 68 | US9227949, 68 | US9655879, 68)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-13-4-6-15(21(30)31)16(10-13)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-3-12(20(27)28)9-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.240n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308429
PNG
(US9655879, 25)
Show SMILES Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O |r|
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0.260n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158097
PNG
(US9024044, 25 | US9227949, 25)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O |r|
Show InChI InChI=1/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/s2
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0.260n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158097
PNG
(US9024044, 25 | US9227949, 25)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@H](CC(O)=O)C(O)=O |r|
Show InChI InChI=1/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/s2
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0.260n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308428
PNG
(US9655879, 24)
Show SMILES Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
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0.270n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158096
PNG
(US9024044, 24 | US9227949, 24)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
Show InChI InChI=1/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/s2
PDB

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0.270n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158096
PNG
(US9024044, 24 | US9227949, 24)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
Show InChI InChI=1/C24H28FN3O7S/c1-3-24(4-2,23(34)28-16(21(31)32)7-10-19(29)30)12-14-6-9-18(36-14)22(33)35-17-8-5-13(20(26)27)11-15(17)25/h5-6,8-9,11,16H,3-4,7,10,12H2,1-2H3,(H3,26,27)(H,28,34)(H,29,30)(H,31,32)/t16-/s2
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0.270n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308123
PNG
(US9655879, 3)
Show SMILES Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O
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0.290n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158075
PNG
(US9024044, 3 | US9227949, 3)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O
Show InChI InChI=1S/C19H20FN3O5S/c1-19(2,18(27)23-9-15(24)25)8-11-4-6-14(29-11)17(26)28-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,27)(H,24,25)
PDB

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0.290n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158075
PNG
(US9024044, 3 | US9227949, 3)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)NCC(O)=O
Show InChI InChI=1S/C19H20FN3O5S/c1-19(2,18(27)23-9-15(24)25)8-11-4-6-14(29-11)17(26)28-13-5-3-10(16(21)22)7-12(13)20/h3-7H,8-9H2,1-2H3,(H3,21,22)(H,23,27)(H,24,25)
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0.290n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308557
PNG
(US9655879, 93)
Show SMILES Cl.CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H](O)C[C@H]1C(O)=O |r|
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0.300n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50268291
PNG
((1-(3,4-dichlorophenyl)-5-(1-isopropylpiperidin-4-...)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc2n(c(cc2c1)C(=O)N1CCC(F)(F)CC1)-c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C28H31Cl2F2N3O2/c1-18(2)33-11-7-21(8-12-33)37-22-4-6-25-19(15-22)16-26(27(36)34-13-9-28(31,32)10-14-34)35(25)20-3-5-23(29)24(30)17-20/h3-6,15-18,21H,7-14H2,1-2H3
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0.300n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM199983
PNG
(US9227949, 93)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N1C[C@H](O)C[C@H]1C(O)=O |r|
Show InChI InChI=1/C22H24FN3O6S/c1-22(2,21(31)26-10-12(27)8-15(26)19(28)29)9-13-4-6-17(33-13)20(30)32-16-5-3-11(18(24)25)7-14(16)23/h3-7,12,15,27H,8-10H2,1-2H3,(H3,24,25)(H,28,29)/t12-,15+/s2
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0.300n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158131
PNG
(US9024044, 59 | US9227949, 59 | US9655879, 59)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.310n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158131
PNG
(US9024044, 59 | US9227949, 59 | US9655879, 59)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.310n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158131
PNG
(US9024044, 59 | US9227949, 59 | US9655879, 59)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-15-8-13(21(30)31)7-14(9-15)22(32)33)11-16-4-6-19(37-16)23(34)36-18-5-3-12(20(27)28)10-17(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.310n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308401
PNG
(US9655879, 19)
Show SMILES Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O |r|
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0.330n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158091
PNG
(US9024044, 19 | US9227949, 19)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O |r|
Show InChI InChI=1/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/s2
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0.330n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158091
PNG
(US9024044, 19 | US9227949, 19)
Show SMILES CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CC(O)=O)C(O)=O |r|
Show InChI InChI=1/C23H26FN3O7S/c1-3-23(4-2,22(33)27-15(20(30)31)10-18(28)29)11-13-6-8-17(35-13)21(32)34-16-7-5-12(19(25)26)9-14(16)24/h5-9,15H,3-4,10-11H2,1-2H3,(H3,25,26)(H,27,33)(H,28,29)(H,30,31)/t15-/s2
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UniChem
US Patent
0.330n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158147
PNG
(US9024044, 75 | US9227949, 75 | US9655879, 75)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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0.390n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM199977
PNG
(US9227949, 87 | US9655879, 87)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O
Show InChI InChI=1S/C17H17FN2O4S/c1-17(2,16(22)23)8-10-4-6-13(25-10)15(21)24-12-5-3-9(14(19)20)7-11(12)18/h3-7H,8H2,1-2H3,(H3,19,20)(H,22,23)
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0.390n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158147
PNG
(US9024044, 75 | US9227949, 75 | US9655879, 75)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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US Patent
0.390n/an/an/an/an/an/a8.0n/a



Ajinomoto Co., Inc.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...


US Patent US9024044 (2015)


BindingDB Entry DOI: 10.7270/Q2F47MVB
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM199977
PNG
(US9227949, 87 | US9655879, 87)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(O)=O
Show InChI InChI=1S/C17H17FN2O4S/c1-17(2,16(22)23)8-10-4-6-13(25-10)15(21)24-12-5-3-9(14(19)20)7-11(12)18/h3-7H,8H2,1-2H3,(H3,19,20)(H,22,23)
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0.390n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158147
PNG
(US9024044, 75 | US9227949, 75 | US9655879, 75)
Show SMILES CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(ccc1C(O)=O)C(O)=O
Show InChI InChI=1S/C25H22FN3O7S/c1-25(2,24(35)29-17-10-13(21(30)31)3-6-15(17)22(32)33)11-14-5-8-19(37-14)23(34)36-18-7-4-12(20(27)28)9-16(18)26/h3-10H,11H2,1-2H3,(H3,27,28)(H,29,35)(H,30,31)(H,32,33)
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US Patent
0.390n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50139391
PNG
((R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofu...)
Show SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N |r|
Show InChI InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3/t16-/m1/s1
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0.400n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Binding affinity to histamine H3 receptor


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50268323
PNG
((5-(1-cyclopropylpiperidin-4-yloxy)-1-(2,2,2-trifl...)
Show SMILES FC(F)(F)Cn1c(cc2cc(OC3CCN(CC3)C3CC3)ccc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C23H28F3N3O3/c24-23(25,26)15-29-20-4-3-19(32-18-5-7-27(8-6-18)17-1-2-17)13-16(20)14-21(29)22(30)28-9-11-31-12-10-28/h3-4,13-14,17-18H,1-2,5-12,15H2
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0.400n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation counting


J Med Chem 52: 3855-68 (2009)


Article DOI: 10.1021/jm900409x
BindingDB Entry DOI: 10.7270/Q2SB46NQ
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158079
PNG
(US9024044, 7 | US9227949, 7 | US9655879, 7)
Show SMILES CN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N
Show InChI InChI=1S/C20H22FN3O5S/c1-20(2,19(28)24(3)10-16(25)26)9-12-5-7-15(30-12)18(27)29-14-6-4-11(17(22)23)8-13(14)21/h4-8H,9-10H2,1-3H3,(H3,22,23)(H,25,26)
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0.410n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM308247
PNG
(US9655879, 11)
Show SMILES Cl.CCC(CC)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)N[C@@H](CO)C(O)=O |r|
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0.410n/an/an/an/an/an/an/an/a



EA Pharma Co., Ltd.

US Patent




US Patent US9655879 (2017)


BindingDB Entry DOI: 10.7270/Q22Z17KS
More data for this
Ligand-Target Pair
Enteropeptidase


(Homo sapiens (Human))
BDBM158079
PNG
(US9024044, 7 | US9227949, 7 | US9655879, 7)
Show SMILES CN(CC(O)=O)C(=O)C(C)(C)Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N
Show InChI InChI=1S/C20H22FN3O5S/c1-20(2,19(28)24(3)10-16(25)26)9-12-5-7-15(30-12)18(27)29-14-6-4-11(17(22)23)8-13(14)21/h4-8H,9-10H2,1-3H3,(H3,22,23)(H,25,26)
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US Patent
0.410n/an/an/an/an/an/a8.0n/a



AJINOMOTO CO., INC.

US Patent


Assay Description
Using a 96 well plate (#3915, Costar), a test compound (25 uL), 400 mM Tris-HCl buffer (pH 8.0, 25 uL) and 0.5 mg/mL, fluorescence enzyme substrate (...


US Patent US9227949 (2016)


BindingDB Entry DOI: 10.7270/Q2959GBT
More data for this
Ligand-Target Pair
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