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Compile Data Set for Download or QSAR

Found 620 hits with Last Name = 'ogawa' and Initial = 's'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360155
PNG
(CHEMBL1929548)
Show SMILES O[C@@H](Cc1cccc(c1)C(F)(F)F)\C=C\[C@H]1CCC(=S)N1CCCCCCC(O)=O |r|
Show InChI InChI=1S/C22H28F3NO3S/c23-22(24,25)17-7-5-6-16(14-17)15-19(27)11-9-18-10-12-20(30)26(18)13-4-2-1-3-8-21(28)29/h5-7,9,11,14,18-19,27H,1-4,8,10,12-13,15H2,(H,28,29)/b11-9+/t18-,19+/m0/s1
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0.380n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360154
PNG
(CHEMBL1929547)
Show SMILES CCCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCCCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C24H35NO3S/c1-2-8-19-9-7-10-20(17-19)18-22(26)14-12-21-13-15-23(29)25(21)16-6-4-3-5-11-24(27)28/h7,9-10,12,14,17,21-22,26H,2-6,8,11,13,15-16,18H2,1H3,(H,27,28)/b14-12+/t21-,22+/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360158
PNG
(CHEMBL1929551)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO3S2/c1-16-4-2-5-17(14-16)15-19(23)9-7-18-8-10-20(26)22(18)11-13-27-12-3-6-21(24)25/h2,4-5,7,9,14,18-19,23H,3,6,8,10-13,15H2,1H3,(H,24,25)/b9-7+/t18-,19+/m0/s1
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0.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360172
PNG
(CHEMBL1929539)
Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CSC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C19H25NO4S2/c21-17(13-15-5-2-1-3-6-15)9-8-16-14-26-19(24)20(16)10-12-25-11-4-7-18(22)23/h1-3,5-6,8-9,16-17,21H,4,7,10-14H2,(H,22,23)/b9-8+/t16-,17+/m0/s1
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0.650n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360156
PNG
(CHEMBL1929549)
Show SMILES O[C@@H](Cc1cccc(F)c1)\C=C\[C@H]1CCC(=S)N1CCCCCCC(O)=O |r|
Show InChI InChI=1S/C21H28FNO3S/c22-17-7-5-6-16(14-17)15-19(24)11-9-18-10-12-20(27)23(18)13-4-2-1-3-8-21(25)26/h5-7,9,11,14,18-19,24H,1-4,8,10,12-13,15H2,(H,25,26)/b11-9+/t18-,19+/m0/s1
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0.690n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50101858
PNG
(4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1
Show InChI InChI=1S/C23H32O6S/c1-29-15-17-5-2-4-16(12-17)13-18(24)7-8-19-20(22(26)14-21(19)25)9-11-30-10-3-6-23(27)28/h2,4-5,7-8,12,18-21,24-25H,3,6,9-11,13-15H2,1H3,(H,27,28)/b8-7+/t18-,19-,20-,21-/m1/s1
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0.700n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360153
PNG
(CHEMBL1929546)
Show SMILES CCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCCCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H33NO3S/c1-2-18-8-7-9-19(16-18)17-21(25)13-11-20-12-14-22(28)24(20)15-6-4-3-5-10-23(26)27/h7-9,11,13,16,20-21,25H,2-6,10,12,14-15,17H2,1H3,(H,26,27)/b13-11+/t20-,21+/m0/s1
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0.830n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360148
PNG
(CHEMBL1929540)
Show SMILES CCc1cccc(C[C@H](O)\C=C\[C@H]2CSC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO4S2/c1-2-16-5-3-6-17(13-16)14-19(23)9-8-18-15-28-21(26)22(18)10-12-27-11-4-7-20(24)25/h3,5-6,8-9,13,18-19,23H,2,4,7,10-12,14-15H2,1H3,(H,24,25)/b9-8+/t18-,19+/m0/s1
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0.880n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360150
PNG
(CHEMBL1929542)
Show SMILES O[C@@H](Cc1cccc(c1)C(F)(F)F)\C=C\[C@H]1CSC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C20H24F3NO4S2/c21-20(22,23)15-4-1-3-14(11-15)12-17(25)7-6-16-13-30-19(28)24(16)8-10-29-9-2-5-18(26)27/h1,3-4,6-7,11,16-17,25H,2,5,8-10,12-13H2,(H,26,27)/b7-6+/t16-,17+/m0/s1
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0.970n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360149
PNG
(CHEMBL1929541)
Show SMILES CCCc1cccc(C[C@H](O)\C=C\[C@H]2CSC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C22H31NO4S2/c1-2-5-17-6-3-7-18(14-17)15-20(24)10-9-19-16-29-22(27)23(19)11-13-28-12-4-8-21(25)26/h3,6-7,9-10,14,19-20,24H,2,4-5,8,11-13,15-16H2,1H3,(H,25,26)/b10-9+/t19-,20+/m0/s1
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0.980n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360173
PNG
(CHEMBL1929544)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CSC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO5S2/c1-27-14-17-5-2-4-16(12-17)13-19(23)8-7-18-15-29-21(26)22(18)9-11-28-10-3-6-20(24)25/h2,4-5,7-8,12,18-19,23H,3,6,9-11,13-15H2,1H3,(H,24,25)/b8-7+/t18-,19+/m0/s1
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1.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360151
PNG
(CHEMBL1929543)
Show SMILES O[C@@H](Cc1cccc(F)c1)\C=C\[C@H]1CSC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C19H24FNO4S2/c20-15-4-1-3-14(11-15)12-17(22)7-6-16-13-27-19(25)21(16)8-10-26-9-2-5-18(23)24/h1,3-4,6-7,11,16-17,22H,2,5,8-10,12-13H2,(H,23,24)/b7-6+/t16-,17+/m0/s1
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1.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360152
PNG
(CHEMBL1929545)
Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=S)N1CCCCCCC(O)=O |r|
Show InChI InChI=1S/C21H29NO3S/c23-19(16-17-8-4-3-5-9-17)13-11-18-12-14-20(26)22(18)15-7-2-1-6-10-21(24)25/h3-5,8-9,11,13,18-19,23H,1-2,6-7,10,12,14-16H2,(H,24,25)/b13-11+/t18-,19+/m0/s1
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1.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360168
PNG
(CHEMBL1929535)
Show SMILES O[C@@H](Cc1cccc(Cl)c1)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C19H24ClNO5S/c20-15-4-1-3-14(11-15)12-17(22)7-6-16-13-26-19(25)21(16)8-10-27-9-2-5-18(23)24/h1,3-4,6-7,11,16-17,22H,2,5,8-10,12-13H2,(H,23,24)/b7-6+/t16-,17+/m0/s1
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1.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50058163
PNG
(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Show SMILES CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c1c(C)cc(C)cc1C |(-10.62,2.69,;-9.29,3.46,;-7.95,2.7,;-6.62,3.48,;-5.28,2.71,;-3.95,3.49,;-3.96,5.03,;-5.27,1.17,;-6.6,.4,;-6.6,-1.14,;-7.94,-1.91,;-5.27,-1.91,;-3.92,-1.14,;-2.44,-1.61,;-1.54,-.35,;-2.46,.9,;-1.99,2.37,;-3.93,.41,;-1.96,-3.07,;-2.99,-4.22,;-4.49,-3.91,;-2.5,-5.68,;-.99,-5.99,;-.51,-7.46,;.03,-4.83,;-.46,-3.38,;.56,-2.22,)|
Show InChI InChI=1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3
PDB
MMDB

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1.80n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360157
PNG
(CHEMBL1929550)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCCCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H33NO4S/c1-28-17-19-8-6-7-18(15-19)16-21(25)12-10-20-11-13-22(29)24(20)14-5-3-2-4-9-23(26)27/h6-8,10,12,15,20-21,25H,2-5,9,11,13-14,16-17H2,1H3,(H,26,27)/b12-10+/t20-,21+/m0/s1
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2n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360166
PNG
(CHEMBL1929533)
Show SMILES O[C@@H](Cc1cccc(c1)C(F)(F)F)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C20H24F3NO5S/c21-20(22,23)15-4-1-3-14(11-15)12-17(25)7-6-16-13-29-19(28)24(16)8-10-30-9-2-5-18(26)27/h1,3-4,6-7,11,16-17,25H,2,5,8-10,12-13H2,(H,26,27)/b7-6+/t16-,17+/m0/s1
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2n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360161
PNG
(CHEMBL1929528)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)[C@@H]2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H32O5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-22(25)21(19)11-13-29-12-3-6-23(26)27/h2,4-5,7,9,14,19-21,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+,21+/m0/s1
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2.40n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360165
PNG
(CHEMBL1929532)
Show SMILES CCCc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C22H31NO5S/c1-2-5-17-6-3-7-18(14-17)15-20(24)10-9-19-16-28-22(27)23(19)11-13-29-12-4-8-21(25)26/h3,6-7,9-10,14,19-20,24H,2,4-5,8,11-13,15-16H2,1H3,(H,25,26)/b10-9+/t19-,20+/m0/s1
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2.40n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360163
PNG
(CHEMBL1929530)
Show SMILES Cc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C20H27NO5S/c1-15-4-2-5-16(12-15)13-18(22)8-7-17-14-26-20(25)21(17)9-11-27-10-3-6-19(23)24/h2,4-5,7-8,12,17-18,22H,3,6,9-11,13-14H2,1H3,(H,23,24)/b8-7+/t17-,18+/m0/s1
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2.5n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360162
PNG
(CHEMBL1929529)
Show SMILES O[C@@H](Cc1ccccc1)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C19H25NO5S/c21-17(13-15-5-2-1-3-6-15)9-8-16-14-25-19(24)20(16)10-12-26-11-4-7-18(22)23/h1-3,5-6,8-9,16-17,21H,4,7,10-14H2,(H,22,23)/b9-8+/t16-,17+/m0/s1
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4.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50357626
PNG
(CHEMBL1915856)
Show SMILES CN1C[C@@H](COc2cc(C)c(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(C)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C27H27ClN2O5/c1-16-10-19(34-15-20-14-30(3)23-6-4-5-7-24(23)35-20)11-17(2)26(16)27(33)29-22-12-18(13-25(31)32)8-9-21(22)28/h4-12,20H,13-15H2,1-3H3,(H,29,33)(H,31,32)/t20-/m0/s1
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6.40n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360171
PNG
(CHEMBL1929538)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO6S/c1-27-14-17-5-2-4-16(12-17)13-19(23)8-7-18-15-28-21(26)22(18)9-11-29-10-3-6-20(24)25/h2,4-5,7-8,12,18-19,23H,3,6,9-11,13-15H2,1H3,(H,24,25)/b8-7+/t18-,19+/m0/s1
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7.20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351489
PNG
(CHEMBL1819614)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(C)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C26H25ClN2O5/c1-16-11-18(33-15-19-14-29(2)23-5-3-4-6-24(23)34-19)8-9-20(16)26(32)28-22-12-17(13-25(30)31)7-10-21(22)27/h3-12,19H,13-15H2,1-2H3,(H,28,32)(H,30,31)/t19-/m0/s1
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7.70n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360164
PNG
(CHEMBL1929531)
Show SMILES CCc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C21H29NO5S/c1-2-16-5-3-6-17(13-16)14-19(23)9-8-18-15-27-21(26)22(18)10-12-28-11-4-7-20(24)25/h3,5-6,8-9,13,18-19,23H,2,4,7,10-12,14-15H2,1H3,(H,24,25)/b9-8+/t18-,19+/m0/s1
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7.90n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360160
PNG
(CHEMBL1929527)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCSCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C22H31NO5S/c1-28-16-18-5-2-4-17(14-18)15-20(24)9-7-19-8-10-21(25)23(19)11-13-29-12-3-6-22(26)27/h2,4-5,7,9,14,19-20,24H,3,6,8,10-13,15-16H2,1H3,(H,26,27)/b9-7+/t19-,20+/m0/s1
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8n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50133507
PNG
(4-Decylamino-6-methyl-cyclohexane-1,2,3-triol | CH...)
Show SMILES CCCCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C17H35NO3/c1-3-4-5-6-7-8-9-10-11-18-14-12-13(2)15(19)17(21)16(14)20/h13-21H,3-12H2,1-2H3
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9n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against beta-galactosidase in bovine liver


Bioorg Med Chem Lett 13: 3461-3 (2003)


BindingDB Entry DOI: 10.7270/Q2FF3RR7
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360159
PNG
(CHEMBL1929526)
Show SMILES COCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=O)N2CCCCCCC(O)=O)c1 |r|
Show InChI InChI=1S/C23H33NO5/c1-29-17-19-8-6-7-18(15-19)16-21(25)12-10-20-11-13-22(26)24(20)14-5-3-2-4-9-23(27)28/h6-8,10,12,15,20-21,25H,2-5,9,11,13-14,16-17H2,1H3,(H,27,28)/b12-10+/t20-,21+/m0/s1
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10n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens (Human))
BDBM50403994
PNG
(CHEMBL2114287)
Show SMILES C[C@@H]1C[C@@H](N)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3-,4-,5-,6-,7-/m1/s1
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12n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidney


Bioorg Med Chem Lett 12: 749-52 (2002)


BindingDB Entry DOI: 10.7270/Q2CF9PDK
More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens (Human))
BDBM50403995
PNG
(CHEMBL2115269)
Show SMILES C[C@@H]1C[C@H](N)[C@@H](O)[C@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C7H15NO3/c1-3-2-4(8)6(10)7(11)5(3)9/h3-7,9-11H,2,8H2,1H3/t3-,4+,5-,6-,7-/m1/s1
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12n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
The compound was tested for the inhibitory activity against alpha-L-Fucosidase in bovine kidney


Bioorg Med Chem Lett 12: 749-52 (2002)


BindingDB Entry DOI: 10.7270/Q2CF9PDK
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351483
PNG
(CHEMBL1819622)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(Cl)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C25H22Cl2N2O5/c1-29-13-17(34-23-5-3-2-4-22(23)29)14-33-16-7-8-18(20(27)12-16)25(32)28-21-10-15(11-24(30)31)6-9-19(21)26/h2-10,12,17H,11,13-14H2,1H3,(H,28,32)(H,30,31)/t17-/m0/s1
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13n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50074456
PNG
(CHEMBL10504 | SC241 | [3-(2-Bromo-4-isopropyl-phen...)
Show SMILES COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C20H27BrN6O2/c1-13(2)15-6-7-17(16(21)12-15)27-20-18(24-25-27)19(22-14(3)23-20)26(8-10-28-4)9-11-29-5/h6-7,12-13H,8-11H2,1-5H3
PDB
MMDB

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14.8n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM85397
PNG
(CRA1000)
Show SMILES CCN(c1nc(C)cc(n1)N1CCC=C(C1)c1cccc(F)c1)c1ccc(CC(C)C)cc1SC |c:14|
Show InChI InChI=1S/C29H35FN4S/c1-6-34(26-13-12-22(15-20(2)3)17-27(26)35-5)29-31-21(4)16-28(32-29)33-14-8-10-24(19-33)23-9-7-11-25(30)18-23/h7,9-13,16-18,20H,6,8,14-15,19H2,1-5H3
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15.7n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50152515
PNG
(CHEMBL364841 | {2-Methyl-1-[4-(4-methyl-3,4-dihydr...)
Show SMILES CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2ccccc12
Show InChI InChI=1S/C28H26N2O5/c1-18-14-23-20(15-27(31)32)6-5-8-24(23)30(18)28(33)19-10-12-21(13-11-19)34-17-22-16-29(2)25-7-3-4-9-26(25)35-22/h3-14,22H,15-17H2,1-2H3,(H,31,32)/t22-/m0/s1
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16n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens (Human))
BDBM50118923
PNG
((1S,2S,3R)-4-Methyl-6-octylamino-cyclohexane-1,2,3...)
Show SMILES CCCCCCCCNC1CC(C)C(O)C(O)C1O
Show InChI InChI=1S/C15H31NO3/c1-3-4-5-6-7-8-9-16-12-10-11(2)13(17)15(19)14(12)18/h11-19H,3-10H2,1-2H3
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16n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Binding affinity against alpha-L-fucosidase in bovine kidney was determined


Bioorg Med Chem Lett 12: 2811-4 (2002)


BindingDB Entry DOI: 10.7270/Q2C24WZJ
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351486
PNG
(CHEMBL1819609)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cccc(CC(O)=O)c3)c(Cl)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C25H23ClN2O5/c1-28-14-19(33-23-8-3-2-7-22(23)28)15-32-18-9-10-20(21(26)13-18)25(31)27-17-6-4-5-16(11-17)12-24(29)30/h2-11,13,19H,12,14-15H2,1H3,(H,27,31)(H,29,30)/t19-/m0/s1
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16n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351484
PNG
(CHEMBL1819623)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3F)c(Cl)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C25H22ClFN2O5/c1-29-13-17(34-23-5-3-2-4-22(23)29)14-33-16-7-8-18(19(26)12-16)25(32)28-21-10-15(11-24(30)31)6-9-20(21)27/h2-10,12,17H,11,13-14H2,1H3,(H,28,32)(H,30,31)/t17-/m0/s1
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17n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351480
PNG
(CHEMBL1819608)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cccc(CC(O)=O)c3)c(C)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C26H26N2O5/c1-17-12-20(32-16-21-15-28(2)23-8-3-4-9-24(23)33-21)10-11-22(17)26(31)27-19-7-5-6-18(13-19)14-25(29)30/h3-13,21H,14-16H2,1-2H3,(H,27,31)(H,29,30)/t21-/m0/s1
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18n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM85398
PNG
(CRA1001)
Show SMILES CCN(c1nc(C)cc(n1)N1CCC=C(C1)c1cccc(F)c1)c1ccc(CC(C)C)cc1Br |c:14|
Show InChI InChI=1S/C28H32BrFN4/c1-5-34(26-12-11-21(14-19(2)3)16-25(26)29)28-31-20(4)15-27(32-28)33-13-7-9-23(18-33)22-8-6-10-24(30)17-22/h6,8-12,15-17,19H,5,7,13-14,18H2,1-4H3
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18.6n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351490
PNG
(CHEMBL1819615)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3F)c(C)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C26H25FN2O5/c1-16-11-18(33-15-19-14-29(2)23-5-3-4-6-24(23)34-19)8-9-20(16)26(32)28-22-12-17(13-25(30)31)7-10-21(22)27/h3-12,19H,13-15H2,1-2H3,(H,28,32)(H,30,31)/t19-/m0/s1
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19n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360167
PNG
(CHEMBL1929534)
Show SMILES O[C@@H](Cc1cccc(F)c1)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C19H24FNO5S/c20-15-4-1-3-14(11-15)12-17(22)7-6-16-13-26-19(25)21(16)8-10-27-9-2-5-18(23)24/h1,3-4,6-7,11,16-17,22H,2,5,8-10,12-13H2,(H,23,24)/b7-6+/t16-,17+/m0/s1
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20n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM85397
PNG
(CRA1000)
Show SMILES CCN(c1nc(C)cc(n1)N1CCC=C(C1)c1cccc(F)c1)c1ccc(CC(C)C)cc1SC |c:14|
Show InChI InChI=1S/C29H35FN4S/c1-6-34(26-13-12-22(15-20(2)3)17-27(26)35-5)29-31-21(4)16-28(32-29)33-14-8-10-24(19-33)23-9-7-11-25(30)18-23/h7,9-13,16-18,20H,6,8,14-15,19H2,1-5H3
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20.6n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50074456
PNG
(CHEMBL10504 | SC241 | [3-(2-Bromo-4-isopropyl-phen...)
Show SMILES COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C
Show InChI InChI=1S/C20H27BrN6O2/c1-13(2)15-6-7-17(16(21)12-15)27-20-18(24-25-27)19(22-14(3)23-20)26(8-10-28-4)9-11-29-5/h6-7,12-13H,8-11H2,1-5H3
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20.7n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM85398
PNG
(CRA1001)
Show SMILES CCN(c1nc(C)cc(n1)N1CCC=C(C1)c1cccc(F)c1)c1ccc(CC(C)C)cc1Br |c:14|
Show InChI InChI=1S/C28H32BrFN4/c1-5-34(26-12-11-21(14-19(2)3)16-25(26)29)28-31-20(4)15-27(32-28)33-13-7-9-23(18-33)22-8-6-10-24(30)17-22/h6,8-12,15-17,19H,5,7,13-14,18H2,1-4H3
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22.3n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by PDSP Ki Database




J Pharmacol Exp Ther 289: 926-35 (1999)


BindingDB Entry DOI: 10.7270/Q2GM85VG
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351494
PNG
(CHEMBL1819619)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3C)c(Cl)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C26H25ClN2O5/c1-16-7-8-17(12-25(30)31)11-22(16)28-26(32)20-10-9-18(13-21(20)27)33-15-19-14-29(2)23-5-3-4-6-24(23)34-19/h3-11,13,19H,12,14-15H2,1-2H3,(H,28,32)(H,30,31)/t19-/m0/s1
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26n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360169
PNG
(CHEMBL1929536)
Show SMILES O[C@@H](Cc1cccc(c1)-c1ccccc1)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C25H29NO5S/c27-23(17-19-6-4-9-21(16-19)20-7-2-1-3-8-20)12-11-22-18-31-25(30)26(22)13-15-32-14-5-10-24(28)29/h1-4,6-9,11-12,16,22-23,27H,5,10,13-15,17-18H2,(H,28,29)/b12-11+/t22-,23+/m0/s1
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28n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50357627
PNG
(CHEMBL1915676)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(C)c2C)Oc2ccccc12 |r|
Show InChI InChI=1S/C27H27ClN2O5/c1-16-17(2)24(34-15-19-14-30(3)23-6-4-5-7-25(23)35-19)11-9-20(16)27(33)29-22-12-18(13-26(31)32)8-10-21(22)28/h4-12,19H,13-15H2,1-3H3,(H,29,33)(H,31,32)/t19-/m0/s1
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28n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Prostanoid EP4 Receptor


(Mus musculus (Mouse))
BDBM50360170
PNG
(CHEMBL1929537)
Show SMILES O[C@@H](Cc1cccc(OC(F)(F)F)c1)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r|
Show InChI InChI=1S/C20H24F3NO6S/c21-20(22,23)30-17-4-1-3-14(12-17)11-16(25)7-6-15-13-29-19(28)24(15)8-10-31-9-2-5-18(26)27/h1,3-4,6-7,12,15-16,25H,2,5,8-11,13H2,(H,26,27)/b7-6+/t15-,16+/m0/s1
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29n/an/an/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter


Bioorg Med Chem 20: 702-13 (2012)

Checked by Author
Article DOI: 10.1016/j.bmc.2011.12.009
BindingDB Entry DOI: 10.7270/Q2CJ8DXN
More data for this
Ligand-Target Pair
Prostanoid DP receptor


(Mus musculus)
BDBM50351481
PNG
(CHEMBL1819611)
Show SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3C)c(C)c2)Oc2ccccc12 |r|
Show InChI InChI=1S/C27H28N2O5/c1-17-8-9-19(14-26(30)31)13-23(17)28-27(32)22-11-10-20(12-18(22)2)33-16-21-15-29(3)24-6-4-5-7-25(24)34-21/h4-13,21H,14-16H2,1-3H3,(H,28,32)(H,30,31)/t21-/m0/s1
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31n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting


Bioorg Med Chem 19: 6935-48 (2011)


Article DOI: 10.1016/j.bmc.2011.08.065
BindingDB Entry DOI: 10.7270/Q2K35V22
More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens (Human))
BDBM50065258
PNG
((2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2...)
Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO3/c1-3-5(9)6(10)4(8)2-7-3/h3-10H,2H2,1H3/t3-,4+,5+,6-/m0/s1
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31n/an/an/an/an/an/an/an/a



Keio University

Curated by ChEMBL


Assay Description
Binding affinity against alpha-L-fucosidase in bovine kidney was determined


Bioorg Med Chem Lett 12: 2811-4 (2002)


BindingDB Entry DOI: 10.7270/Q2C24WZJ
More data for this
Ligand-Target Pair
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