Compile Data Set for Download or QSAR

Found 99 hits with Last Name = 'penzotti' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145742 ((R)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-...) Show SMILES Cc1ccccc1[C@@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	154	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145735 (1-(2-Bromo-phenyl)-1-(2,4-dichloro-phenylamino)-4-...) Show SMILES Clc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C21H17BrCl2N2O/c22-17-4-2-1-3-16(17)21(26-19-7-6-15(23)13-18(19)24)20(27)8-5-14-9-11-25-12-10-14/h1-4,6-7,9-13,21,26H,5,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145751 ((R)-1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-...) Show SMILES Cc1ccc(N[C@@H](C(=O)CCc2ccncc2)c2ccccc2C)c(Cl)c1 Show InChI InChI=1S/C23H23ClN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145754 (1-(2,4-Dichloro-phenylamino)-1-(2-ethyl-phenyl)-4-...) Show SMILES CCc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H22Cl2N2O/c1-2-17-5-3-4-6-19(17)23(27-21-9-8-18(24)15-20(21)25)22(28)10-7-16-11-13-26-14-12-16/h3-6,8-9,11-15,23,27H,2,7,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145731 (1-(2,4-Dichloro-phenylamino)-1-(2,6-dimethyl-pheny...) Show SMILES Cc1cccc(C)c1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H22Cl2N2O/c1-15-4-3-5-16(2)22(15)23(27-20-8-7-18(24)14-19(20)25)21(28)9-6-17-10-12-26-13-11-17/h3-5,7-8,10-14,23,27H,6,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145749 (1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-o-to...) Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145732 (2-(2,4-Dichloro-phenylamino)-1-(3-hydroxy-4-methox...) Show SMILES COc1ccc(cc1O)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C Show InChI InChI=1S/C22H19Cl2NO3/c1-13-5-3-4-6-16(13)21(25-18-9-8-15(23)12-17(18)24)22(27)14-7-10-20(28-2)19(26)11-14/h3-12,21,25-26H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	387	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145745 (1-(2-Fluoro-4-methyl-phenylamino)-4-pyridin-4-yl-1...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(F)c1 Show InChI InChI=1S/C23H23FN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	439	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145758 (1-(4-Chloro-2-trifluoromethyl-phenylamino)-4-pyrid...) Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1C(F)(F)F)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H20ClF3N2O/c1-15-4-2-3-5-18(15)22(21(30)9-6-16-10-12-28-13-11-16)29-20-8-7-17(24)14-19(20)23(25,26)27/h2-5,7-8,10-14,22,29H,6,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	469	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145733 (1-(2,4-Dichloro-phenylamino)-1-(4-fluoro-2-methyl-...) Show SMILES Cc1cc(F)ccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H19Cl2FN2O/c1-14-12-17(25)4-5-18(14)22(27-20-6-3-16(23)13-19(20)24)21(28)7-2-15-8-10-26-11-9-15/h3-6,8-13,22,27H,2,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	512	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145739 (CHEMBL81912 | N-{3-[2-(2-Bromo-phenyl)-2-(2,4-dich...) Show SMILES CC(=O)Nc1cccc(c1)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1Br Show InChI InChI=1S/C22H17BrCl2N2O2/c1-13(28)26-16-6-4-5-14(11-16)22(29)21(17-7-2-3-8-18(17)23)27-20-10-9-15(24)12-19(20)25/h2-12,21,27H,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	514	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145741 ((R)-1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenyl...) Show SMILES Cc1ccc(N[C@@H](C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C22H20BrClN2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	546	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity of compound towards human corticotropin releasing factor (h-CRF1) receptor showed a 2-fold activity in racemic mixture				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145755 (1-(4-Methyl-2-trifluoromethyl-phenylamino)-4-pyrid...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(c1)C(F)(F)F Show InChI InChI=1S/C24H23F3N2O/c1-16-7-9-21(20(15-16)24(25,26)27)29-23(19-6-4-3-5-17(19)2)22(30)10-8-18-11-13-28-14-12-18/h3-7,9,11-15,23,29H,8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	641	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145740 (1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C=C)c(Cl)c1 Show InChI InChI=1S/C24H23ClN2O/c1-3-19-6-4-5-7-20(19)24(27-22-10-8-17(2)16-21(22)25)23(28)11-9-18-12-14-26-15-13-18/h3-8,10,12-16,24,27H,1,9,11H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	752	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145729 (1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(Cl)c1 Show InChI InChI=1S/C23H23ClN2O/c1-16-7-9-21(20(24)15-16)26-23(19-6-4-3-5-17(19)2)22(27)10-8-18-11-13-25-14-12-18/h3-7,9,11-15,23,26H,8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	922	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145759 (1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-(2-t...) Show SMILES FC(F)(F)c1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H17Cl2F3N2O/c23-15-6-7-19(18(24)13-15)29-21(16-3-1-2-4-17(16)22(25,26)27)20(30)8-5-14-9-11-28-12-10-14/h1-4,6-7,9-13,21,29H,5,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145730 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C22H20BrClN2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity of compound towards human Corticotropin releasing factor receptor 1				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145737 (2-(2-Bromo-phenyl)-2-(2-chloro-4-methyl-phenylamin...) Show SMILES COc1ccc(cc1O)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br Show InChI InChI=1S/C22H19BrClNO3/c1-13-7-9-18(17(24)11-13)25-21(15-5-3-4-6-16(15)23)22(27)14-8-10-20(28-2)19(26)12-14/h3-12,21,25-26H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145764 (3-[2-(2-Bromo-phenyl)-2-(2-chloro-4-methyl-phenyla...) Show SMILES CNC(=O)c1cccc(c1)C(=O)C(Nc1ccc(C)cc1Cl)c1ccccc1Br Show InChI InChI=1S/C23H20BrClN2O2/c1-14-10-11-20(19(25)12-14)27-21(17-8-3-4-9-18(17)24)22(28)15-6-5-7-16(13-15)23(29)26-2/h3-13,21,27H,1-2H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145761 ((S)-1-(2,4-Dichloro-phenylamino)-4-pyridin-4-yl-1-...) Show SMILES Cc1ccccc1[C@H](Nc1ccc(Cl)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-4-2-3-5-18(15)22(26-20-8-7-17(23)14-19(20)24)21(27)9-6-16-10-12-25-13-11-16/h2-5,7-8,10-14,22,26H,6,9H2,1H3/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145728 (1-(2-Chloro-4-methyl-phenylamino)-1-(2-isopropyl-p...) Show SMILES CC(C)c1ccccc1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C25H27ClN2O/c1-17(2)20-6-4-5-7-21(20)25(28-23-10-8-18(3)16-22(23)26)24(29)11-9-19-12-14-27-15-13-19/h4-8,10,12-17,25,28H,9,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145752 (1-(2-Chloro-4-methyl-phenylamino)-1-(2-chloro-phen...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Cl)c(Cl)c1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-6-8-20(19(24)14-15)26-22(17-4-2-3-5-18(17)23)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity of compound towards human Corticotropin releasing factor receptor 1				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145753 (1-(2-Chloro-4-methyl-phenylamino)-1-(3-chloro-phen...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2cccc(Cl)c2)c(Cl)c1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-5-7-20(19(24)13-15)26-22(17-3-2-4-18(23)14-17)21(27)8-6-16-9-11-25-12-10-16/h2-5,7,9-14,22,26H,6,8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145763 (1-(2-Bromo-phenyl)-1-(2-chloro-phenylamino)-4-pyri...) Show SMILES Clc1ccccc1NC(C(=O)CCc1ccncc1)c1ccccc1Br Show InChI InChI=1S/C21H18BrClN2O/c22-17-6-2-1-5-16(17)21(25-19-8-4-3-7-18(19)23)20(26)10-9-15-11-13-24-14-12-15/h1-8,11-14,21,25H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145765 (1-(2-Chloro-4-methyl-phenylamino)-1-phenyl-4-pyrid...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C22H21ClN2O/c1-16-7-9-20(19(23)15-16)25-22(18-5-3-2-4-6-18)21(26)10-8-17-11-13-24-14-12-17/h2-7,9,11-15,22,25H,8,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145766 (1-(2-Chloro-4-methyl-phenylamino)-1-(4-chloro-phen...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C22H20Cl2N2O/c1-15-2-8-20(19(24)14-15)26-22(17-4-6-18(23)7-5-17)21(27)9-3-16-10-12-25-13-11-16/h2,4-8,10-14,22,26H,3,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145760 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2cccnc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C22H20BrClN2O/c1-15-8-10-20(19(24)13-15)26-22(17-6-2-3-7-18(17)23)21(27)11-9-16-5-4-12-25-14-16/h2-8,10,12-14,22,26H,9,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145756 (1-(2-Chloro-4-methyl-phenylamino)-1-(2,6-dimethoxy...) Show SMILES COc1cccc(OC)c1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C24H25ClN2O3/c1-16-7-9-19(18(25)15-16)27-24(20(28)10-8-17-11-13-26-14-12-17)23-21(29-2)5-4-6-22(23)30-3/h4-7,9,11-15,24,27H,8,10H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145757 (1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...) Show SMILES Cc1ccc(cc1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H23ClN2O/c1-16-3-7-19(8-4-16)23(26-21-9-5-17(2)15-20(21)24)22(27)10-6-18-11-13-25-14-12-18/h3-5,7-9,11-15,23,26H,6,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145762 (1-(2-Chloro-4-methyl-phenylamino)-1-(2,4-dimethoxy...) Show SMILES COc1ccc(C(Nc2ccc(C)cc2Cl)C(=O)CCc2ccncc2)c(OC)c1 Show InChI InChI=1S/C24H25ClN2O3/c1-16-4-8-21(20(25)14-16)27-24(19-7-6-18(29-2)15-23(19)30-3)22(28)9-5-17-10-12-26-13-11-17/h4,6-8,10-15,24,27H,5,9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145750 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)Cc2ccncc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C21H18BrClN2O/c1-14-6-7-19(18(23)12-14)25-21(16-4-2-3-5-17(16)22)20(26)13-15-8-10-24-11-9-15/h2-12,21,25H,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145747 (2-(2,4-Dichloro-phenylamino)-1-(3,4-dimethoxy-phen...) Show SMILES COc1ccc(cc1OC)C(=O)C(Nc1ccc(Cl)cc1Cl)c1ccccc1C Show InChI InChI=1S/C23H21Cl2NO3/c1-14-6-4-5-7-17(14)22(26-19-10-9-16(24)13-18(19)25)23(27)15-8-11-20(28-2)21(12-15)29-3/h4-13,22,26H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145746 (1-(2-Chloro-4-methyl-phenylamino)-4-pyridin-4-yl-1...) Show SMILES Cc1cccc(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H23ClN2O/c1-16-4-3-5-19(14-16)23(26-21-8-6-17(2)15-20(21)24)22(27)9-7-18-10-12-25-13-11-18/h3-6,8,10-15,23,26H,7,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145748 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2cnc[nH]2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C20H19BrClN3O/c1-13-6-8-18(17(22)10-13)25-20(15-4-2-3-5-16(15)21)19(26)9-7-14-11-23-12-24-14/h2-6,8,10-12,20,25H,7,9H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145744 (1-(2-Chloro-4-methyl-phenylamino)-1-(3-methoxy-phe...) Show SMILES COc1cccc(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H23ClN2O2/c1-16-6-8-21(20(24)14-16)26-23(18-4-3-5-19(15-18)28-2)22(27)9-7-17-10-12-25-13-11-17/h3-6,8,10-15,23,26H,7,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145743 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccccc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C23H21BrClNO/c1-16-11-13-21(20(25)15-16)26-23(18-9-5-6-10-19(18)24)22(27)14-12-17-7-3-2-4-8-17/h2-11,13,15,23,26H,12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145738 (1-(2-Chloro-4-methyl-phenylamino)-1-(2-methoxy-phe...) Show SMILES COc1ccccc1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C23H23ClN2O2/c1-16-7-9-20(19(24)15-16)26-23(18-5-3-4-6-22(18)28-2)21(27)10-8-17-11-13-25-14-12-17/h3-7,9,11-15,23,26H,8,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145736 (1-(2-Chloro-4-methyl-phenylamino)-1-(2-fluoro-phen...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2F)c(Cl)c1 Show InChI InChI=1S/C22H20ClFN2O/c1-15-6-8-20(18(23)14-15)26-22(17-4-2-3-5-19(17)24)21(27)9-7-16-10-12-25-13-11-16/h2-6,8,10-14,22,26H,7,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity of compound towards human Corticotropin releasing factor receptor 1				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145734 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccc(F)cc2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C23H20BrClFNO/c1-15-6-12-21(20(25)14-15)27-23(18-4-2-3-5-19(18)24)22(28)13-9-16-7-10-17(26)11-8-16/h2-8,10-12,14,23,27H,9,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145727 (2-(2,4-Dichloro-phenylamino)-1-(3-hydroxy-phenyl)-...) Show SMILES Cc1ccccc1C(Nc1ccc(Cl)cc1Cl)C(=O)c1cccc(O)c1 Show InChI InChI=1S/C21H17Cl2NO2/c1-13-5-2-3-8-17(13)20(21(26)14-6-4-7-16(25)11-14)24-19-10-9-15(22)12-18(19)23/h2-12,20,24-25H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145726 (1-(2-Bromo-phenyl)-1-(2-chloro-4-methyl-phenylamin...) Show SMILES Cc1ccc(NC(C(=O)CCc2ccccn2)c2ccccc2Br)c(Cl)c1 Show InChI InChI=1S/C22H20BrClN2O/c1-15-9-11-20(19(24)14-15)26-22(17-7-2-3-8-18(17)23)21(27)12-10-16-6-4-5-13-25-16/h2-9,11,13-14,22,26H,10,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145724 (1-(2-Bromo-phenyl)-1-[(2-chloro-phenyl)-methyl-ami...) Show SMILES CN(C(C(=O)CCc1ccncc1)c1ccccc1Br)c1ccccc1Cl Show InChI InChI=1S/C22H20BrClN2O/c1-26(20-9-5-4-8-19(20)24)22(17-6-2-3-7-18(17)23)21(27)11-10-16-12-14-25-15-13-16/h2-9,12-15,22H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50145725 (1-(2-Chloro-4-methyl-phenylamino)-1-(2,5-dimethoxy...) Show SMILES COc1ccc(OC)c(c1)C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 Show InChI InChI=1S/C24H25ClN2O3/c1-16-4-7-21(20(25)14-16)27-24(19-15-18(29-2)6-9-23(19)30-3)22(28)8-5-17-10-12-26-13-11-17/h4,6-7,9-15,24,27H,5,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharma Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human corticotropin releasing factor (h-CRF1) receptor				J Med Chem 47: 2426-9 (2004) Article DOI: 10.1021/jm049974i BindingDB Entry DOI: 10.7270/Q2PZ5888
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7755 (4-({[(12Z)-11-oxo-3-thia-5,10-diazatricyclo[7.3.0....) Show SMILES O=C1Nc2ccc3ncsc3c2C1C=Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:13.15| Show InChI InChI=1S/C21H15N5O3S2/c27-21-15(19-16(25-21)8-9-17-20(19)30-12-24-17)11-23-13-4-6-14(7-5-13)31(28,29)26-18-3-1-2-10-22-18/h1-12,15H,(H,22,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Rational Discovery LLC Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 2				J Med Chem 48: 3313-8 (2005) Article DOI: 10.1021/jm049066l BindingDB Entry DOI: 10.7270/Q2F76DC7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7646 (CHEMBL102926 | Imidazo[1,2-a]pyridine deriv. 6 | N...) Show SMILES CN(C)CC(O)COc1ccc(Nc2nccc(n2)-c2c(C)nc3ccccn23)cc1 Show InChI InChI=1S/C23H26N6O2/c1-16-22(29-13-5-4-6-21(29)25-16)20-11-12-24-23(27-20)26-17-7-9-19(10-8-17)31-15-18(30)14-28(2)3/h4-13,18,30H,14-15H2,1-3H3,(H,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Rational Discovery LLC Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 2				J Med Chem 48: 3313-8 (2005) Article DOI: 10.1021/jm049066l BindingDB Entry DOI: 10.7270/Q2F76DC7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES OCc1ccc(o1)C(=O)NN=Cc1cc(C(O)=O)c(Nc2ccc(I)cc2F)c(F)c1F |w:11.12| Show InChI InChI=1S/C20H13F3IN3O5/c21-13-6-10(24)1-3-14(13)26-18-12(20(30)31)5-9(16(22)17(18)23)7-25-27-19(29)15-4-2-11(8-28)32-15/h1-7,26,28H,8H2,(H,27,29)(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to SRC (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES OCc1ccc(o1)C(=O)NN=Cc1cc(C(O)=O)c(Nc2ccc(I)cc2F)c(F)c1F |w:11.12| Show InChI InChI=1S/C20H13F3IN3O5/c21-13-6-10(24)1-3-14(13)26-18-12(20(30)31)5-9(16(22)17(18)23)7-25-27-19(29)15-4-2-11(8-28)32-15/h1-7,26,28H,8H2,(H,27,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ABL (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES OCc1ccc(o1)C(=O)NN=Cc1cc(C(O)=O)c(Nc2ccc(I)cc2F)c(F)c1F |w:11.12| Show InChI InChI=1S/C20H13F3IN3O5/c21-13-6-10(24)1-3-14(13)26-18-12(20(30)31)5-9(16(22)17(18)23)7-25-27-19(29)15-4-2-11(8-28)32-15/h1-7,26,28H,8H2,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to LCK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES CS(=O)(=O)c1ccc(CNCc2cc(C(O)=O)c(Nc3ccc(I)cc3F)c(F)c2F)cc1 Show InChI InChI=1S/C22H18F3IN2O4S/c1-33(31,32)15-5-2-12(3-6-15)10-27-11-13-8-16(22(29)30)21(20(25)19(13)24)28-18-7-4-14(26)9-17(18)23/h2-9,27-28H,10-11H2,1H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to Aurora A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7615 (2,4-bis anilino pyrimidine deriv. 11 | 4-N-(2,5-di...) Show SMILES CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(Cl)ccc3Cl)n2)cc1 Show InChI InChI=1S/C21H23Cl2N5O2/c1-28(2)12-16(29)13-30-17-6-4-15(5-7-17)25-21-24-10-9-20(27-21)26-19-11-14(22)3-8-18(19)23/h3-11,16,29H,12-13H2,1-2H3,(H2,24,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rational Discovery LLC Curated by ChEMBL					Assay Description Inhibition of Cyclin-dependent kinase 2				J Med Chem 48: 3313-8 (2005) Article DOI: 10.1021/jm049066l BindingDB Entry DOI: 10.7270/Q2F76DC7
					More data for this Ligand-Target Pair				3D Structure (crystal)

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