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Compile Data Set for Download or QSAR

Found 47 hits with Last Name = 'pichat' and Initial = 'p'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442630
PNG
(CHEMBL2441638)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CCCCC2)c(C)c1 |r|
Show InChI InChI=1S/C23H35N3O/c1-17-15-20(25-14-12-21(16-25)26-13-6-7-18(26)2)10-11-22(17)24-23(27)19-8-4-3-5-9-19/h10-11,15,18-19,21H,3-9,12-14,16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1
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0.390n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443217
PNG
(CHEMBL3087669)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1 |r|
Show InChI InChI=1S/C22H30N4O2/c1-14-12-18(25-11-9-19(13-25)26-10-5-6-15(26)2)7-8-20(14)23-22(27)21-16(3)24-28-17(21)4/h7-8,12,15,19H,5-6,9-11,13H2,1-4H3,(H,23,27)/t15-,19-/m0/s1
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0.400n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442628
PNG
(CHEMBL2441640)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CCCC2)c(C)c1 |r|
Show InChI InChI=1S/C22H33N3O/c1-16-14-19(9-10-21(16)23-22(26)18-7-3-4-8-18)24-13-11-20(15-24)25-12-5-6-17(25)2/h9-10,14,17-18,20H,3-8,11-13,15H2,1-2H3,(H,23,26)/t17-,20-/m0/s1
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0.5n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442627
PNG
(CHEMBL2441641)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2C(C)(C)C2(C)C)c(C)c1 |r|
Show InChI InChI=1S/C24H37N3O/c1-16-14-18(26-13-11-19(15-26)27-12-7-8-17(27)2)9-10-20(16)25-22(28)21-23(3,4)24(21,5)6/h9-10,14,17,19,21H,7-8,11-13,15H2,1-6H3,(H,25,28)/t17-,19-/m0/s1
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0.550n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442629
PNG
(CHEMBL2441639)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CC3CCC2C3)c(C)c1 |r|
Show InChI InChI=1S/C24H35N3O/c1-16-12-20(26-11-9-21(15-26)27-10-3-4-17(27)2)7-8-23(16)25-24(28)22-14-18-5-6-19(22)13-18/h7-8,12,17-19,21-22H,3-6,9-11,13-15H2,1-2H3,(H,25,28)/t17-,18?,19?,21-,22?/m0/s1
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0.550n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442626
PNG
(CHEMBL2441642)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)CC2CCCC2)c(C)c1 |r|
Show InChI InChI=1S/C23H35N3O/c1-17-14-20(25-13-11-21(16-25)26-12-5-6-18(26)2)9-10-22(17)24-23(27)15-19-7-3-4-8-19/h9-10,14,18-19,21H,3-8,11-13,15-16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1
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0.850n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50443217
PNG
(CHEMBL3087669)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1 |r|
Show InChI InChI=1S/C22H30N4O2/c1-14-12-18(25-11-9-19(13-25)26-10-5-6-15(26)2)7-8-20(14)23-22(27)21-16(3)24-28-17(21)4/h7-8,12,15,19H,5-6,9-11,13H2,1-4H3,(H,23,27)/t15-,19-/m0/s1
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KEGG

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0.900n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]-methylhistamine from rat histamine H3 receptor (445 amino acid residues) transfected in human 293 cells after 1 hr by scintillat...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442632
PNG
(CHEMBL2441636)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CCOCC2)c(C)c1 |r|
Show InChI InChI=1S/C22H33N3O2/c1-16-14-19(24-11-7-20(15-24)25-10-3-4-17(25)2)5-6-21(16)23-22(26)18-8-12-27-13-9-18/h5-6,14,17-18,20H,3-4,7-13,15H2,1-2H3,(H,23,26)/t17-,20-/m0/s1
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0.970n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443216
PNG
(CHEMBL3087667)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cc(C)no2)c(C)c1 |r|
Show InChI InChI=1S/C21H28N4O2/c1-14-11-17(24-10-8-18(13-24)25-9-4-5-16(25)3)6-7-19(14)22-21(26)20-12-15(2)23-27-20/h6-7,11-12,16,18H,4-5,8-10,13H2,1-3H3,(H,22,26)/t16-,18-/m0/s1
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1.10n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443227
PNG
(CHEMBL3087356)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cccc(C)n2)c(C)c1 |r|
Show InChI InChI=1S/C23H30N4O/c1-16-14-19(26-13-11-20(15-26)27-12-5-7-18(27)3)9-10-21(16)25-23(28)22-8-4-6-17(2)24-22/h4,6,8-10,14,18,20H,5,7,11-13,15H2,1-3H3,(H,25,28)/t18-,20-/m0/s1
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1.40n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443226
PNG
(CHEMBL3087357)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2ccoc2)c(C)c1 |r|
Show InChI InChI=1S/C21H27N3O2/c1-15-12-18(5-6-20(15)22-21(25)17-8-11-26-14-17)23-10-7-19(13-23)24-9-3-4-16(24)2/h5-6,8,11-12,14,16,19H,3-4,7,9-10,13H2,1-2H3,(H,22,25)/t16-,19-/m0/s1
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1.80n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50437067
PNG
(CHEMBL2403550)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cc(F)ccc2C)c(C)c1 |r|
Show InChI InChI=1S/C24H30FN3O/c1-16-6-7-19(25)14-22(16)24(29)26-23-9-8-20(13-17(23)2)27-12-10-21(15-27)28-11-4-5-18(28)3/h6-9,13-14,18,21H,4-5,10-12,15H2,1-3H3,(H,26,29)/t18-,21-/m0/s1
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2.5n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443225
PNG
(CHEMBL3087671)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)c(C)n1 |r|
Show InChI InChI=1S/C21H26F2N4O2S/c1-14-4-3-10-27(14)16-9-11-26(13-16)21-8-7-20(15(2)24-21)25-30(28,29)17-5-6-18(22)19(23)12-17/h5-8,12,14,16,25H,3-4,9-11,13H2,1-2H3/t14-,16-/m0/s1
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2.5n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443224
PNG
(CHEMBL3087670)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2ccccc2)c(C)n1 |r|
Show InChI InChI=1S/C22H28N4O/c1-16-7-6-13-26(16)19-12-14-25(15-19)21-11-10-20(17(2)23-21)24-22(27)18-8-4-3-5-9-18/h3-5,8-11,16,19H,6-7,12-15H2,1-2H3,(H,24,27)/t16-,19-/m0/s1
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3n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442640
PNG
(CHEMBL2441653)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)CC2CCCC2)cc1
Show InChI InChI=1S/C22H33N3O/c1-17-5-4-13-25(17)21-12-14-24(16-21)20-10-8-19(9-11-20)23-22(26)15-18-6-2-3-7-18/h8-11,17-18,21H,2-7,12-16H2,1H3,(H,23,26)
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3.10n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443223
PNG
(CHEMBL3087358)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2ccco2)c(C)c1 |r|
Show InChI InChI=1S/C21H27N3O2/c1-15-13-17(7-8-19(15)22-21(25)20-6-4-12-26-20)23-11-9-18(14-23)24-10-3-5-16(24)2/h4,6-8,12-13,16,18H,3,5,9-11,14H2,1-2H3,(H,22,25)/t16-,18-/m0/s1
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3.90n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442631
PNG
(CHEMBL2441637)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(NC(=O)C2CCOCC2)c(C)c1 |r|
Show InChI InChI=1S/C22H33N3O2/c1-16-14-19(24-11-7-20(15-24)25-10-3-4-17(25)2)5-6-21(16)23-22(26)18-8-12-27-13-9-18/h5-6,14,17-18,20H,3-4,7-13,15H2,1-2H3,(H,23,26)/t17-,20+/m0/s1
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3.90n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443222
PNG
(CHEMBL3087673)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cccc3ccccc23)c(C)n1 |r|
Show InChI InChI=1S/C26H30N4O/c1-18-7-6-15-30(18)21-14-16-29(17-21)25-13-12-24(19(2)27-25)28-26(31)23-11-5-9-20-8-3-4-10-22(20)23/h3-5,8-13,18,21H,6-7,14-17H2,1-2H3,(H,28,31)/t18-,21-/m0/s1
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4.20n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443221
PNG
(CHEMBL3087668)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2coc(C)n2)c(C)c1 |r|
Show InChI InChI=1S/C21H28N4O2/c1-14-11-17(24-10-8-18(12-24)25-9-4-5-15(25)2)6-7-19(14)23-21(26)20-13-27-16(3)22-20/h6-7,11,13,15,18H,4-5,8-10,12H2,1-3H3,(H,23,26)/t15-,18-/m0/s1
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4.60n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443220
PNG
(CHEMBL3087359)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cc(C)n[nH]2)c(C)c1 |r|
Show InChI InChI=1S/C21H29N5O/c1-14-11-17(25-10-8-18(13-25)26-9-4-5-16(26)3)6-7-19(14)22-21(27)20-12-15(2)23-24-20/h6-7,11-12,16,18H,4-5,8-10,13H2,1-3H3,(H,22,27)(H,23,24)/t16-,18-/m0/s1
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4.70n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443219
PNG
(CHEMBL3087672)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)Cc2ccccc2)c(C)n1 |r|
Show InChI InChI=1S/C23H30N4O/c1-17-7-6-13-27(17)20-12-14-26(16-20)22-11-10-21(18(2)24-22)25-23(28)15-19-8-4-3-5-9-19/h3-5,8-11,17,20H,6-7,12-16H2,1-2H3,(H,25,28)/t17-,20-/m0/s1
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4.90n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442631
PNG
(CHEMBL2441637)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(NC(=O)C2CCOCC2)c(C)c1 |r|
Show InChI InChI=1S/C22H33N3O2/c1-16-14-19(24-11-7-20(15-24)25-10-3-4-17(25)2)5-6-21(16)23-22(26)18-8-12-27-13-9-18/h5-6,14,17-18,20H,3-4,7-13,15H2,1-2H3,(H,23,26)/t17-,20+/m0/s1
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6.80n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442624
PNG
(CHEMBL2441635)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCO2)c(C)c1
Show InChI InChI=1S/C21H31N3O2/c1-15-13-17(7-8-19(15)22-21(25)20-6-4-12-26-20)23-11-9-18(14-23)24-10-3-5-16(24)2/h7-8,13,16,18,20H,3-6,9-12,14H2,1-2H3,(H,22,25)
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7.30n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442625
PNG
(CHEMBL2441643)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CCCO2)c(C)c1 |r|
Show InChI InChI=1S/C21H31N3O2/c1-15-13-17(7-8-19(15)22-21(25)20-6-4-12-26-20)23-11-9-18(14-23)24-10-3-5-16(24)2/h7-8,13,16,18,20H,3-6,9-12,14H2,1-2H3,(H,22,25)/t16-,18-,20?/m0/s1
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7.30n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442626
PNG
(CHEMBL2441642)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)CC2CCCC2)c(C)c1 |r|
Show InChI InChI=1S/C23H35N3O/c1-17-14-20(25-13-11-21(16-25)26-12-5-6-18(26)2)9-10-22(17)24-23(27)15-19-7-3-4-8-19/h9-10,14,18-19,21H,3-8,11-13,15-16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1
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8.40n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442637
PNG
(CHEMBL2441658)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCO2)cc1
Show InChI InChI=1S/C20H29N3O2/c1-15-4-2-11-23(15)18-10-12-22(14-18)17-8-6-16(7-9-17)21-20(24)19-5-3-13-25-19/h6-9,15,18-19H,2-5,10-14H2,1H3,(H,21,24)
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8.70n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442630
PNG
(CHEMBL2441638)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CCCCC2)c(C)c1 |r|
Show InChI InChI=1S/C23H35N3O/c1-17-15-20(25-14-12-21(16-25)26-13-6-7-18(26)2)10-11-22(17)24-23(27)19-8-4-3-5-9-19/h10-11,15,18-19,21H,3-9,12-14,16H2,1-2H3,(H,24,27)/t18-,21-/m0/s1
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9n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442645
PNG
(CHEMBL2441647)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC2)c(C)c1
Show InChI InChI=1S/C20H29N3O/c1-14-12-17(7-8-19(14)21-20(24)16-5-6-16)22-11-9-18(13-22)23-10-3-4-15(23)2/h7-8,12,15-16,18H,3-6,9-11,13H2,1-2H3,(H,21,24)
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9.60n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442646
PNG
(CHEMBL2441646)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC2)cc1
Show InChI InChI=1S/C19H27N3O/c1-14-3-2-11-22(14)18-10-12-21(13-18)17-8-6-16(7-9-17)20-19(23)15-4-5-15/h6-9,14-15,18H,2-5,10-13H2,1H3,(H,20,23)
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9.70n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442639
PNG
(CHEMBL2441655)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)CC2CCCC2)cc1C
Show InChI InChI=1S/C23H35N3O/c1-17-14-20(24-23(27)15-19-7-3-4-8-19)9-10-22(17)25-13-11-21(16-25)26-12-5-6-18(26)2/h9-10,14,18-19,21H,3-8,11-13,15-16H2,1-2H3,(H,24,27)
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11n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50443218
PNG
(CHEMBL3087360)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2cc(C)n(C)n2)c(C)c1 |r|
Show InChI InChI=1S/C22H31N5O/c1-15-12-18(26-11-9-19(14-26)27-10-5-6-16(27)2)7-8-20(15)23-22(28)21-13-17(3)25(4)24-21/h7-8,12-13,16,19H,5-6,9-11,14H2,1-4H3,(H,23,28)/t16-,19-/m0/s1
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11n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442635
PNG
(CHEMBL2441660)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCN2C(C)=O)cc1
Show InChI InChI=1S/C22H32N4O2/c1-16-5-3-12-25(16)20-11-14-24(15-20)19-9-7-18(8-10-19)23-22(28)21-6-4-13-26(21)17(2)27/h7-10,16,20-21H,3-6,11-15H2,1-2H3,(H,23,28)
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14n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442644
PNG
(CHEMBL2441648)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC2)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H26F3N3O/c1-13-3-2-9-26(13)16-8-10-25(12-16)15-6-7-18(17(11-15)20(21,22)23)24-19(27)14-4-5-14/h6-7,11,13-14,16H,2-5,8-10,12H2,1H3,(H,24,27)
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15n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442648
PNG
(CHEMBL2441664)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC3CCC2C3)cc1
Show InChI InChI=1S/C23H33N3O/c1-16-3-2-11-26(16)21-10-12-25(15-21)20-8-6-19(7-9-20)24-23(27)22-14-17-4-5-18(22)13-17/h6-9,16-18,21-22H,2-5,10-15H2,1H3,(H,24,27)
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16n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442636
PNG
(CHEMBL2441659)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCO2)cc1C
Show InChI InChI=1S/C21H31N3O2/c1-15-13-17(22-21(25)20-6-4-12-26-20)7-8-19(15)23-11-9-18(14-23)24-10-3-5-16(24)2/h7-8,13,16,18,20H,3-6,9-12,14H2,1-2H3,(H,22,25)
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17n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442638
PNG
(CHEMBL2441657)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCOCC2)cc1C
Show InChI InChI=1S/C22H33N3O2/c1-16-14-19(23-22(26)18-8-12-27-13-9-18)5-6-21(16)24-11-7-20(15-24)25-10-3-4-17(25)2/h5-6,14,17-18,20H,3-4,7-13,15H2,1-2H3,(H,23,26)
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17n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442643
PNG
(CHEMBL2441649)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC2)cc1C
Show InChI InChI=1S/C20H29N3O/c1-14-12-17(21-20(24)16-5-6-16)7-8-19(14)22-11-9-18(13-22)23-10-3-4-15(23)2/h7-8,12,15-16,18H,3-6,9-11,13H2,1-2H3,(H,21,24)
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18n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442629
PNG
(CHEMBL2441639)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2CC3CCC2C3)c(C)c1 |r|
Show InChI InChI=1S/C24H35N3O/c1-16-12-20(26-11-9-21(15-26)27-10-3-4-17(27)2)7-8-23(16)25-24(28)22-14-18-5-6-19(22)13-18/h7-8,12,17-19,21-22H,3-6,9-11,13-15H2,1-2H3,(H,25,28)/t17-,18?,19?,21-,22?/m0/s1
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20n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442627
PNG
(CHEMBL2441641)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)C2C(C)(C)C2(C)C)c(C)c1 |r|
Show InChI InChI=1S/C24H37N3O/c1-16-14-18(26-13-11-19(15-26)27-12-7-8-17(27)2)9-10-20(16)25-22(28)21-23(3,4)24(21,5)6/h9-10,14,17,19,21H,7-8,11-13,15H2,1-6H3,(H,25,28)/t17-,19-/m0/s1
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37n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442633
PNG
(CHEMBL2441662)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCN2C(C)=O)cc1C
Show InChI InChI=1S/C23H34N4O2/c1-16-14-19(24-23(29)22-7-5-12-27(22)18(3)28)8-9-21(16)25-13-10-20(15-25)26-11-4-6-17(26)2/h8-9,14,17,20,22H,4-7,10-13,15H2,1-3H3,(H,24,29)
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45n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442634
PNG
(CHEMBL2441661)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CCCN2C(C)=O)c(C)c1
Show InChI InChI=1S/C23H34N4O2/c1-16-14-19(25-13-10-20(15-25)26-11-4-6-17(26)2)8-9-21(16)24-23(29)22-7-5-12-27(22)18(3)28/h8-9,14,17,20,22H,4-7,10-13,15H2,1-3H3,(H,24,29)
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58n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442641
PNG
(CHEMBL2441652)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1C
Show InChI InChI=1S/C24H37N3O/c1-16-14-18(25-22(28)21-23(3,4)24(21,5)6)9-10-20(16)26-13-11-19(15-26)27-12-7-8-17(27)2/h9-10,14,17,19,21H,7-8,11-13,15H2,1-6H3,(H,25,28)
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66n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442647
PNG
(CHEMBL2441645)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2CC3CCC2C3)cc1C
Show InChI InChI=1S/C24H35N3O/c1-16-12-20(25-24(28)22-14-18-5-6-19(22)13-18)7-8-23(16)26-11-9-21(15-26)27-10-3-4-17(27)2/h7-8,12,17-19,21-22H,3-6,9-11,13-15H2,1-2H3,(H,25,28)
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130n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))
BDBM50442642
PNG
(CHEMBL2441650)
Show SMILES CC1CCCN1C1CCN(C1)c1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1
Show InChI InChI=1S/C23H35N3O/c1-16-7-6-13-26(16)19-12-14-25(15-19)18-10-8-17(9-11-18)24-21(27)20-22(2,3)23(20,4)5/h8-11,16,19-20H,6-7,12-15H2,1-5H3,(H,24,27)
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144n/an/an/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 23: 6141-5 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.006
BindingDB Entry DOI: 10.7270/Q24T6KT6
More data for this
Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2


(Canis familiaris)
BDBM50443217
PNG
(CHEMBL3087669)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1 |r|
Show InChI InChI=1S/C22H30N4O2/c1-14-12-18(25-11-9-19(13-25)26-10-5-6-15(26)2)7-8-20(14)23-22(27)21-16(3)24-28-17(21)4/h7-8,12,15,19H,5-6,9-11,13H2,1-4H3,(H,23,27)/t15-,19-/m0/s1
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n/an/a 4.40E+4n/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Inhibition of canine ERG current transfected in CHO cells by patch clamp assay


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Cytochrome P450 2C9


(Homo sapiens (Human))
BDBM50443217
PNG
(CHEMBL3087669)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1 |r|
Show InChI InChI=1S/C22H30N4O2/c1-14-12-18(25-11-9-19(13-25)26-10-5-6-15(26)2)7-8-20(14)23-22(27)21-16(3)24-28-17(21)4/h7-8,12,15,19H,5-6,9-11,13H2,1-4H3,(H,23,27)/t15-,19-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Inhibition of CYP2C9 (unknown origin) after 4 hrs


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair
Cytochrome P450 2C19


(Homo sapiens (Human))
BDBM50443217
PNG
(CHEMBL3087669)
Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1 |r|
Show InChI InChI=1S/C22H30N4O2/c1-14-12-18(25-11-9-19(13-25)26-10-5-6-15(26)2)7-8-20(14)23-22(27)21-16(3)24-28-17(21)4/h7-8,12,15,19H,5-6,9-11,13H2,1-4H3,(H,23,27)/t15-,19-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Sanofi US

Curated by ChEMBL


Assay Description
Inhibition of CYP2C19 (unknown origin) after 4 hrs


Bioorg Med Chem Lett 23: 6269-73 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.081
BindingDB Entry DOI: 10.7270/Q27D2WK2
More data for this
Ligand-Target Pair