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Compile Data Set for Download or QSAR

Found 34 hits with Last Name = 'ping' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM92906
PNG
(CHK1 compound 1)
Show SMILES O[C@H]1CN(C[C@H]1O)C(=O)c1[nH]c2cc(NC(=O)C3C[C@H]3c3ccccc3)cc3c2c1cn[nH]c3=O |r|
Show InChI InChI=1S/C25H21N5O5/c31-19-10-30(11-20(19)32)25(35)22-17-9-26-29-24(34)16-6-13(7-18(28-22)21(16)17)27-23(33)15-8-14(15)12-4-2-1-3-5-12/h1-7,9,14-15,19-20,31-32H,8,10-11H2,(H,27,33)/t14-,15?,19-,20+/m0/s1
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1.75 -49.5n/an/an/an/an/a7.422



Pfizer



Assay Description
The inhibitors reported in this study bind to CHK1 according to a general mechanism illustrated in Scheme 1 where E, S, and I stand for enzyme, subst...


Biochemistry 48: 9823-30 (2009)


Article DOI: 10.1021/bi900258v
BindingDB Entry DOI: 10.7270/Q25M649B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM92906
PNG
(CHK1 compound 1)
Show SMILES O[C@H]1CN(C[C@H]1O)C(=O)c1[nH]c2cc(NC(=O)C3C[C@H]3c3ccccc3)cc3c2c1cn[nH]c3=O |r|
Show InChI InChI=1S/C25H21N5O5/c31-19-10-30(11-20(19)32)25(35)22-17-9-26-29-24(34)16-6-13(7-18(28-22)21(16)17)27-23(33)15-8-14(15)12-4-2-1-3-5-12/h1-7,9,14-15,19-20,31-32H,8,10-11H2,(H,27,33)/t14-,15?,19-,20+/m0/s1
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5.14 -46.5n/an/an/an/an/a8.020



Pfizer



Assay Description
Surface plasmon resonance (SPR) biosensor binding studies were conducted using a Biacore 3000 instrument (GE Healtchare).


Biochemistry 48: 9823-30 (2009)


Article DOI: 10.1021/bi900258v
BindingDB Entry DOI: 10.7270/Q25M649B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM92908
PNG
(CHK1 compound 3)
Show SMILES CC(C)(C)c1ccc(cc1[N+](O)=O)C(=O)NC(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C22H21N3O4/c1-22(2,3)17-12-11-15(13-19(17)25(28)29)20(26)24-21(27)23-18-10-6-8-14-7-4-5-9-16(14)18/h4-13H,1-3H3,(H2-,23,24,26,27,28,29)/p+1
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146 -38.6n/an/an/an/an/a7.422



Pfizer



Assay Description
The inhibitors reported in this study bind to CHK1 according to a general mechanism illustrated in Scheme 1 where E, S, and I stand for enzyme, subst...


Biochemistry 48: 9823-30 (2009)


Article DOI: 10.1021/bi900258v
BindingDB Entry DOI: 10.7270/Q25M649B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM92908
PNG
(CHK1 compound 3)
Show SMILES CC(C)(C)c1ccc(cc1[N+](O)=O)C(=O)NC(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C22H21N3O4/c1-22(2,3)17-12-11-15(13-19(17)25(28)29)20(26)24-21(27)23-18-10-6-8-14-7-4-5-9-16(14)18/h4-13H,1-3H3,(H2-,23,24,26,27,28,29)/p+1
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290 -36.7n/an/an/an/an/a8.020



Pfizer



Assay Description
Surface plasmon resonance (SPR) biosensor binding studies were conducted using a Biacore 3000 instrument (GE Healtchare).


Biochemistry 48: 9823-30 (2009)


Article DOI: 10.1021/bi900258v
BindingDB Entry DOI: 10.7270/Q25M649B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))
BDBM92907
PNG
(CHK1 compound 2)
Show SMILES CC(OC(=O)Nc1ccc(Cl)c(Cl)c1)c1nc2ccccc2[nH]1
Show InChI InChI=1S/C16H13Cl2N3O2/c1-9(15-20-13-4-2-3-5-14(13)21-15)23-16(22)19-10-6-7-11(17)12(18)8-10/h2-9H,1H3,(H,19,22)(H,20,21)
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1.89E+3 -32.3n/an/an/an/an/a7.422



Pfizer



Assay Description
The inhibitors reported in this study bind to CHK1 according to a general mechanism illustrated in Scheme 1 where E, S, and I stand for enzyme, subst...


Biochemistry 48: 9823-30 (2009)


Article DOI: 10.1021/bi900258v
BindingDB Entry DOI: 10.7270/Q25M649B
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Melanocortin receptor 1


(Mus musculus)
BDBM50354719
PNG
(CHEMBL1834391)
Show SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |r,wU:26.27,8.10,4.4,74.76,92.96,108.113,wD:14.23,33.33,42.42,52.53,63.65,104.110,(10.67,7.94,;10.68,6.4,;9.35,5.63,;9.35,4.09,;8.01,3.31,;6.68,4.09,;5.35,3.31,;5.35,1.78,;4.01,4.09,;4.01,5.63,;5.35,6.4,;2.68,3.31,;1.35,4.09,;1.35,5.63,;.01,3.31,;.01,1.78,;1.35,1,;2.67,1.77,;4,1.01,;4,-.54,;5.33,-1.31,;2.67,-1.31,;1.35,-.53,;-1.32,4.09,;-2.66,3.31,;-2.66,1.78,;-3.99,4.09,;-5.32,3.31,;-3.99,5.63,;-5.32,6.4,;8.01,1.78,;6.68,1,;9.35,1,;9.35,-.53,;8.01,-1.31,;8.01,-2.84,;6.68,-3.62,;5.35,-2.84,;6.68,-5.15,;10.68,-1.31,;12.02,-.53,;10.68,-2.84,;12.02,-3.62,;12.02,-5.15,;10.68,-5.93,;10.52,-7.46,;9.02,-7.78,;8.25,-6.45,;9.28,-5.3,;13.35,-2.84,;13.35,-1.31,;14.68,-3.62,;16.02,-2.84,;16.02,-1.31,;17.36,-.53,;18.68,-1.3,;20.02,-.53,;20.02,1,;18.68,1.78,;17.36,1,;17.36,-3.62,;17.36,-5.15,;18.69,-2.84,;20.02,-3.62,;20.02,-5.15,;21.35,-5.93,;21.35,-7.46,;22.69,-8.24,;22.69,-9.77,;21.35,-10.55,;24.02,-10.55,;21.35,-2.84,;21.35,-1.31,;22.69,-3.62,;24.02,-2.84,;24.02,-1.31,;25.36,-.53,;26.76,-1.16,;27.79,-.02,;27.03,1.32,;27.5,2.78,;26.48,3.93,;24.97,3.61,;24.49,2.15,;25.52,1,;25.36,-3.62,;25.36,-5.15,;26.7,-2.84,;28.03,-3.62,;29.36,-2.84,;29.36,-1.31,;30.69,-3.62,;32.03,-2.84,;32.03,-1.31,;30.69,-.53,;30.69,1,;32.03,1.78,;32.03,3.31,;33.37,-3.62,;34.7,-2.84,;33.37,-5.15,;32.11,-6.07,;32.59,-7.53,;34.13,-7.53,;34.61,-6.06,;35.91,-5.24,;35.92,-3.7,;37.24,-6.01,;38.58,-5.25,;38.58,-3.72,;39.92,-2.96,;37.26,-2.94,;39.9,-6.04,;39.89,-7.58,;41.24,-5.28,)|
Show InChI InChI=1S/C76H109N21O18/c1-4-5-18-51(89-73(113)59(40-99)95-71(111)55(91-65(105)49(78)39-98)33-44-23-25-47(100)26-24-44)67(107)90-53(27-28-62(102)103)69(109)94-58(35-46-37-82-41-86-46)72(112)92-56(32-43-15-7-6-8-16-43)70(110)88-52(21-13-30-83-76(80)81)68(108)93-57(34-45-36-84-50-19-10-9-17-48(45)50)66(106)85-38-61(101)87-54(20-11-12-29-77)75(115)97-31-14-22-60(97)74(114)96-63(42(2)3)64(79)104/h6-10,15-17,19,23-26,36-37,41-42,49,51-60,63,84,98-100H,4-5,11-14,18,20-22,27-35,38-40,77-78H2,1-3H3,(H2,79,104)(H,82,86)(H,85,106)(H,87,101)(H,88,110)(H,89,113)(H,90,107)(H,91,105)(H,92,112)(H,93,108)(H,94,109)(H,95,111)(H,96,114)(H,102,103)(H4,80,81,83)/t49-,51-,52-,53-,54-,55-,56+,57-,58-,59-,60-,63-/m0/s1
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n/an/a 0.210n/an/an/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma counting


Bioorg Med Chem Lett 21: 5757-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.017
BindingDB Entry DOI: 10.7270/Q2H132DZ
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50354718
PNG
(CHEMBL1834392)
Show SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NCCCCCCN=[N+]=[N-])C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |r,wU:26.29,8.10,4.4,83.85,101.105,117.122,wD:14.23,42.42,51.51,61.62,72.74,113.119,(18.25,-8.83,;18.25,-10.37,;16.92,-11.14,;16.92,-12.68,;15.59,-13.46,;14.26,-12.68,;12.92,-13.46,;12.92,-14.99,;11.58,-12.68,;11.58,-11.14,;12.92,-10.37,;10.25,-13.46,;8.92,-12.68,;8.92,-11.14,;7.58,-13.46,;7.58,-14.99,;8.92,-15.77,;10.25,-15,;11.57,-15.76,;11.57,-17.31,;12.9,-18.08,;10.24,-18.08,;8.92,-17.3,;6.25,-12.68,;4.91,-13.46,;4.91,-14.99,;3.58,-12.68,;3.58,-11.14,;2.25,-10.37,;2.25,-13.46,;.91,-12.69,;-.41,-13.46,;-1.75,-12.7,;-3.08,-13.47,;-4.4,-12.71,;-5.73,-13.48,;-7.06,-12.72,;-8.6,-12.71,;-10.14,-12.7,;15.59,-14.99,;14.26,-15.77,;16.92,-15.77,;16.92,-17.3,;15.59,-18.08,;15.59,-19.61,;14.26,-20.39,;12.92,-19.61,;14.26,-21.93,;18.25,-18.08,;19.59,-17.3,;18.25,-19.61,;19.59,-20.39,;19.59,-21.93,;18.25,-22.7,;18.1,-24.23,;16.59,-24.55,;15.82,-23.22,;16.86,-22.07,;20.93,-19.61,;20.93,-18.08,;22.26,-20.39,;23.59,-19.61,;23.59,-18.08,;24.93,-17.3,;26.26,-18.08,;27.59,-17.3,;27.59,-15.77,;26.26,-14.99,;24.93,-15.77,;24.93,-20.39,;24.93,-21.93,;26.27,-19.61,;27.6,-20.39,;27.6,-21.93,;28.93,-22.7,;28.93,-24.24,;30.27,-25.01,;30.27,-26.55,;28.93,-27.33,;31.6,-27.33,;28.93,-19.61,;28.93,-18.08,;30.27,-20.39,;31.6,-19.61,;31.6,-18.08,;32.94,-17.3,;34.34,-17.93,;35.38,-16.79,;34.61,-15.45,;35.09,-13.99,;34.06,-12.84,;32.55,-13.16,;32.07,-14.62,;33.1,-15.77,;32.94,-20.39,;32.94,-21.93,;34.28,-19.61,;35.61,-20.39,;36.94,-19.61,;36.94,-18.08,;38.28,-20.39,;39.61,-19.61,;39.61,-18.08,;38.28,-17.3,;38.28,-15.77,;39.61,-14.99,;39.61,-13.46,;40.95,-20.39,;42.28,-19.61,;40.95,-21.93,;39.7,-22.84,;40.17,-24.3,;41.71,-24.3,;42.2,-22.84,;43.49,-22.01,;43.5,-20.47,;44.82,-22.79,;46.16,-22.03,;46.17,-20.49,;47.51,-19.73,;44.84,-19.71,;47.49,-22.81,;47.47,-24.35,;48.83,-22.05,)|
Show InChI InChI=1S/C82H120N24O18/c1-4-5-22-56(97-79(122)65(46-108)103-76(119)61(39-50-27-29-53(109)30-28-50)100-78(121)64(45-107)89-34-15-6-7-16-36-94-105-87)72(115)98-58(31-32-68(111)112)74(117)102-63(41-52-43-88-47-93-52)77(120)99-60(38-49-19-9-8-10-20-49)75(118)96-57(25-17-35-90-82(85)86)73(116)101-62(40-51-42-91-55-23-12-11-21-54(51)55)71(114)92-44-67(110)95-59(24-13-14-33-83)81(124)106-37-18-26-66(106)80(123)104-69(48(2)3)70(84)113/h8-12,19-21,23,27-30,42-43,47-48,56-66,69,89,91,107-109H,4-7,13-18,22,24-26,31-41,44-46,83H2,1-3H3,(H2,84,113)(H,88,93)(H,92,114)(H,95,110)(H,96,118)(H,97,122)(H,98,115)(H,99,120)(H,100,121)(H,101,116)(H,102,117)(H,103,119)(H,104,123)(H,111,112)(H4,85,86,90)/t56-,57-,58-,59-,60+,61-,62-,63-,64-,65-,66-,69-/m0/s1
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n/an/a 0.25n/an/an/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma counting


Bioorg Med Chem Lett 21: 5757-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.017
BindingDB Entry DOI: 10.7270/Q2H132DZ
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50354717
PNG
(CHEMBL1834393)
Show SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |r,wU:26.29,8.10,4.4,101.104,119.124,135.141,wD:14.23,60.61,69.70,79.81,90.93,131.138,(18.92,-28.29,;18.93,-29.83,;17.6,-30.6,;17.6,-32.14,;16.26,-32.92,;14.93,-32.14,;13.59,-32.92,;13.59,-34.45,;12.25,-32.14,;12.25,-30.6,;13.59,-29.83,;10.92,-32.92,;9.58,-32.14,;9.58,-30.6,;8.25,-32.92,;8.25,-34.45,;9.58,-35.23,;10.91,-34.46,;12.24,-35.22,;12.24,-36.77,;13.58,-37.54,;10.91,-37.54,;9.58,-36.76,;6.92,-32.14,;5.57,-32.92,;5.57,-34.45,;4.24,-32.14,;4.24,-30.6,;2.91,-29.83,;2.91,-32.92,;1.57,-32.15,;1.57,-30.61,;.24,-32.92,;-1.09,-32.16,;.38,-31.8,;.38,-30.27,;-1.12,-29.93,;-.04,-28.83,;-.45,-27.35,;-1.93,-26.96,;.64,-26.26,;-1.48,-28.45,;-3.03,-28.45,;-3.37,-29.93,;-4.47,-28.83,;-5.96,-29.23,;-7.04,-28.15,;-6.35,-30.72,;-4.84,-30.29,;-4.83,-31.81,;-3.32,-32.14,;-4.42,-33.23,;-4.03,-34.72,;-2.55,-35.12,;-5.12,-35.8,;-2.97,-33.65,;-1.43,-33.65,;16.26,-34.45,;14.93,-35.23,;17.6,-35.23,;17.6,-36.77,;16.26,-37.54,;16.26,-39.08,;14.93,-39.86,;13.59,-39.08,;14.93,-41.39,;18.93,-37.54,;20.27,-36.77,;18.93,-39.08,;20.27,-39.86,;20.27,-41.39,;18.93,-42.17,;18.77,-43.7,;17.27,-44.02,;16.5,-42.69,;17.53,-41.54,;21.6,-39.08,;21.6,-37.54,;22.94,-39.86,;24.27,-39.08,;24.27,-37.54,;25.61,-36.77,;26.94,-37.54,;28.28,-36.76,;28.28,-35.23,;26.94,-34.45,;25.61,-35.23,;25.61,-39.86,;25.61,-41.39,;26.95,-39.08,;28.28,-39.86,;28.28,-41.39,;29.62,-42.17,;29.62,-43.71,;30.96,-44.48,;30.96,-46.02,;29.62,-46.8,;32.29,-46.8,;29.62,-39.08,;29.62,-37.54,;30.96,-39.86,;32.29,-39.08,;32.29,-37.54,;33.63,-36.77,;35.03,-37.39,;36.07,-36.25,;35.3,-34.91,;35.78,-33.45,;34.75,-32.3,;33.24,-32.62,;32.76,-34.09,;33.79,-35.23,;33.63,-39.86,;33.63,-41.39,;34.97,-39.08,;36.3,-39.86,;37.63,-39.08,;37.63,-37.54,;38.97,-39.86,;40.3,-39.08,;40.3,-37.54,;38.97,-36.77,;38.97,-35.23,;40.3,-34.45,;40.3,-32.92,;41.64,-39.86,;42.98,-39.08,;41.64,-41.39,;40.39,-42.31,;40.87,-43.77,;42.41,-43.77,;42.89,-42.31,;44.19,-41.48,;44.2,-39.94,;45.52,-42.26,;46.86,-41.49,;46.87,-39.95,;48.21,-39.2,;45.54,-39.17,;48.19,-42.28,;48.17,-43.82,;49.53,-41.52,)|
Show InChI InChI=1S/C92H135N25O25/c1-4-5-18-62(105-89(140)71(52-119)111-86(137)67(41-56-23-25-59(120)26-24-56)108-88(139)70(51-118)103-74(122)47-113-32-34-114(48-76(125)126)36-38-116(50-78(129)130)39-37-115(35-33-113)49-77(127)128)82(133)106-64(27-28-75(123)124)84(135)110-69(43-58-45-97-53-101-58)87(138)107-66(40-55-15-7-6-8-16-55)85(136)104-63(21-13-30-98-92(95)96)83(134)109-68(42-57-44-99-61-19-10-9-17-60(57)61)81(132)100-46-73(121)102-65(20-11-12-29-93)91(142)117-31-14-22-72(117)90(141)112-79(54(2)3)80(94)131/h6-10,15-17,19,23-26,44-45,53-54,62-72,79,99,118-120H,4-5,11-14,18,20-22,27-43,46-52,93H2,1-3H3,(H2,94,131)(H,97,101)(H,100,132)(H,102,121)(H,103,122)(H,104,136)(H,105,140)(H,106,133)(H,107,138)(H,108,139)(H,109,134)(H,110,135)(H,111,137)(H,112,141)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H4,95,96,98)/t62-,63-,64-,65-,66+,67-,68-,69-,70-,71-,72-,79-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.590n/an/an/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma counting


Bioorg Med Chem Lett 21: 5757-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.017
BindingDB Entry DOI: 10.7270/Q2H132DZ
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50354716
PNG
(CHEMBL1834394)
Show SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NCCCCCCn1nnc2c1CCCCCC2(F)C(=O)NCCCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |r,wU:26.29,8.10,4.4,127.132,145.152,161.169,wD:14.23,86.89,95.98,105.109,116.121,157.166,(27.78,-6.77,;27.78,-8.31,;26.45,-9.09,;26.45,-10.63,;25.11,-11.4,;23.78,-10.63,;22.45,-11.4,;22.45,-12.94,;21.1,-10.63,;21.1,-9.09,;22.45,-8.31,;19.77,-11.4,;18.44,-10.63,;18.44,-9.09,;17.1,-11.4,;17.1,-12.94,;18.44,-13.72,;19.77,-12.95,;21.09,-13.71,;21.09,-15.26,;22.43,-16.03,;19.76,-16.03,;18.44,-15.25,;15.77,-10.63,;14.43,-11.4,;14.43,-12.94,;13.09,-10.63,;13.09,-9.09,;11.76,-8.31,;11.76,-11.4,;10.42,-10.64,;9.1,-11.41,;7.76,-10.65,;6.43,-11.42,;5.1,-10.66,;3.77,-11.43,;2.44,-10.66,;2.27,-9.13,;.77,-8.81,;.14,-10.04,;1.04,-11.29,;.79,-12.81,;-.44,-13.71,;-1.97,-13.47,;-2.87,-12.23,;-2.63,-10.7,;-1.38,-9.8,;-.62,-8.46,;-2.72,-9.02,;-4.05,-9.78,;-2.71,-7.48,;-4.03,-6.7,;-4.02,-5.16,;-5.35,-4.39,;-5.34,-2.85,;-6.67,-2.07,;-6.66,-.53,;-7.98,.24,;-5.32,.23,;-5.31,1.76,;-4.02,.95,;-2.93,2.02,;-3.73,3.34,;-2.18,3.32,;-1.4,4.64,;-2.16,5.98,;.14,4.63,;-2.91,4.63,;-3.98,5.73,;-5.29,4.95,;-5.27,6.5,;-6.59,7.29,;-6.56,8.84,;-7.93,6.54,;-6.57,5.76,;-7.66,4.69,;-6.84,3.37,;-8.39,3.41,;-9.18,2.09,;-10.72,2.13,;-8.44,.75,;-7.68,2.07,;-6.62,.97,;25.11,-12.94,;23.78,-13.72,;26.45,-13.72,;26.45,-15.25,;25.11,-16.03,;25.11,-17.57,;23.78,-18.34,;22.45,-17.57,;23.78,-19.88,;27.78,-16.03,;29.12,-15.25,;27.78,-17.57,;29.12,-18.34,;29.12,-19.88,;27.78,-20.66,;27.63,-22.19,;26.12,-22.51,;25.35,-21.18,;26.38,-20.03,;30.46,-17.57,;30.46,-16.03,;31.79,-18.34,;33.13,-17.57,;33.13,-16.03,;34.47,-15.25,;35.8,-16.03,;37.13,-15.25,;37.13,-13.72,;35.8,-12.94,;34.47,-13.72,;34.47,-18.34,;34.47,-19.88,;35.8,-17.57,;37.14,-18.34,;37.14,-19.88,;38.47,-20.66,;38.47,-22.2,;39.81,-22.97,;39.81,-24.51,;38.47,-25.29,;41.15,-25.29,;38.47,-17.57,;38.47,-16.03,;39.81,-18.34,;41.15,-17.57,;41.15,-16.03,;42.48,-15.25,;43.89,-15.88,;44.92,-14.74,;44.15,-13.4,;44.63,-11.94,;43.6,-10.79,;42.1,-11.11,;41.61,-12.57,;42.65,-13.72,;42.48,-18.34,;42.48,-19.88,;43.82,-17.57,;45.16,-18.34,;46.49,-17.57,;46.49,-16.03,;47.82,-18.34,;49.16,-17.57,;49.16,-16.03,;47.82,-15.25,;47.82,-13.72,;49.16,-12.94,;49.16,-11.4,;50.5,-18.34,;51.83,-17.57,;50.5,-19.88,;49.25,-20.8,;49.72,-22.26,;51.26,-22.26,;51.75,-20.79,;53.04,-19.97,;53.06,-18.42,;54.38,-20.74,;55.72,-19.98,;55.72,-18.44,;57.07,-17.69,;54.4,-17.66,;57.04,-20.77,;57.03,-22.31,;58.39,-20.01,)|
Show InChI InChI=1S/C111H167FN30O26/c1-4-5-27-77(127-106(165)86(67-144)133-103(162)82(56-71-33-35-74(145)36-34-71)130-105(164)85(66-143)118-41-18-6-7-21-46-142-87-31-12-9-16-39-111(112,96(87)135-136-142)109(168)120-43-20-19-42-119-90(147)62-137-47-49-138(63-92(150)151)51-53-140(65-94(154)155)54-52-139(50-48-137)64-93(152)153)99(158)128-79(37-38-91(148)149)101(160)132-84(58-73-60-117-68-124-73)104(163)129-81(55-70-24-10-8-11-25-70)102(161)126-78(30-22-44-121-110(115)116)100(159)131-83(57-72-59-122-76-28-14-13-26-75(72)76)98(157)123-61-89(146)125-80(29-15-17-40-113)108(167)141-45-23-32-88(141)107(166)134-95(69(2)3)97(114)156/h8,10-11,13-14,24-26,28,33-36,59-60,68-69,77-86,88,95,118,122,143-145H,4-7,9,12,15-23,27,29-32,37-58,61-67,113H2,1-3H3,(H2,114,156)(H,117,124)(H,119,147)(H,120,168)(H,123,157)(H,125,146)(H,126,161)(H,127,165)(H,128,158)(H,129,163)(H,130,164)(H,131,159)(H,132,160)(H,133,162)(H,134,166)(H,148,149)(H,150,151)(H,152,153)(H,154,155)(H4,115,116,121)/t77-,78-,79-,80-,81+,82-,83-,84-,85-,86-,88-,95-,111?/m0/s1
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UniChem
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n/an/a 0.760n/an/an/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma counting


Bioorg Med Chem Lett 21: 5757-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.017
BindingDB Entry DOI: 10.7270/Q2H132DZ
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50354715
PNG
(CHEMBL1834395)
Show SMILES CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NCCCCCCn1nnc2c1CCCCCC2(F)C(=O)NCCCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O |r,wU:26.29,8.10,4.4,120.125,138.145,154.162,wD:14.23,79.82,88.91,98.102,109.114,150.159,(30.34,-37.71,;30.34,-39.25,;29.01,-40.02,;29.01,-41.56,;27.68,-42.34,;26.34,-41.56,;25.01,-42.34,;25.01,-43.87,;23.67,-41.56,;23.67,-40.02,;25.01,-39.25,;22.33,-42.34,;21,-41.56,;21,-40.02,;19.66,-42.34,;19.66,-43.87,;21,-44.65,;22.33,-43.88,;23.66,-44.65,;23.66,-46.19,;24.99,-46.96,;22.32,-46.96,;21,-46.18,;18.33,-41.56,;16.99,-42.34,;16.99,-43.87,;15.66,-41.56,;15.66,-40.02,;14.32,-39.25,;14.32,-42.34,;12.99,-41.57,;11.66,-42.35,;10.32,-41.58,;9,-42.35,;7.67,-41.59,;6.34,-42.36,;5,-41.6,;4.83,-40.06,;3.33,-39.75,;2.7,-40.98,;3.6,-42.22,;3.36,-43.75,;2.12,-44.64,;.6,-44.4,;-.31,-43.16,;-.07,-41.64,;1.18,-40.73,;1.94,-39.4,;-.16,-39.95,;-1.49,-40.71,;-.15,-38.41,;-1.47,-37.63,;-1.46,-36.1,;-2.79,-35.32,;-2.78,-33.78,;-4.1,-33,;-4.09,-31.47,;-5.42,-30.69,;-2.76,-30.71,;-2.74,-29.17,;-1.3,-28.62,;-.56,-27.29,;-.86,-25.78,;.46,-24.99,;1.81,-25.73,;3.12,-24.93,;1.84,-27.27,;-2.04,-24.82,;-3.58,-24.85,;-4.74,-25.85,;-6.09,-25.1,;-7.41,-25.89,;-8.75,-25.14,;-7.38,-27.43,;-4.98,-27.36,;-4.19,-28.68,;27.68,-43.87,;26.34,-44.65,;29.01,-44.65,;29.01,-46.19,;27.68,-46.96,;27.68,-48.5,;26.34,-49.28,;25.01,-48.5,;26.34,-50.81,;30.34,-46.96,;31.69,-46.19,;30.34,-48.5,;31.69,-49.28,;31.69,-50.81,;30.34,-51.59,;30.19,-53.12,;28.68,-53.45,;27.91,-52.11,;28.94,-50.96,;33.02,-48.5,;33.02,-46.96,;34.35,-49.28,;35.69,-48.5,;35.69,-46.96,;37.03,-46.19,;38.36,-46.96,;39.69,-46.19,;39.69,-44.65,;38.36,-43.87,;37.03,-44.65,;37.03,-49.28,;37.03,-50.81,;38.36,-48.5,;39.7,-49.28,;39.7,-50.81,;41.03,-51.59,;41.03,-53.13,;42.37,-53.91,;42.37,-55.44,;41.03,-56.22,;43.71,-56.22,;41.03,-48.5,;41.03,-46.96,;42.37,-49.28,;43.71,-48.5,;43.71,-46.96,;45.04,-46.19,;46.45,-46.81,;47.48,-45.67,;46.71,-44.33,;47.19,-42.87,;46.17,-41.72,;44.66,-42.04,;44.17,-43.51,;45.21,-44.65,;45.04,-49.28,;45.04,-50.81,;46.38,-48.5,;47.72,-49.28,;49.05,-48.5,;49.05,-46.96,;50.39,-49.28,;51.72,-48.5,;51.72,-46.96,;50.39,-46.19,;50.39,-44.65,;51.72,-43.87,;51.72,-42.34,;53.06,-49.28,;54.4,-48.5,;53.06,-50.81,;51.81,-51.73,;52.28,-53.19,;53.83,-53.19,;54.31,-51.73,;55.6,-50.9,;55.62,-49.36,;56.94,-51.68,;58.28,-50.92,;58.29,-49.38,;59.63,-48.62,;56.96,-48.59,;59.61,-51.7,;59.59,-53.25,;60.95,-50.94,)|
Show InChI InChI=1S/C107H160FN29O24/c1-4-5-27-74(123-102(158)83(64-139)129-99(155)79(54-68-33-35-71(140)36-34-68)126-101(157)82(63-138)114-41-18-6-7-21-46-137-84-31-12-9-16-39-107(108,92(84)131-132-137)105(161)116-43-20-19-42-115-87(142)60-133-47-49-134(61-89(145)146)51-52-135(50-48-133)62-90(147)148)95(151)124-76(37-38-88(143)144)97(153)128-81(56-70-58-113-65-120-70)100(156)125-78(53-67-24-10-8-11-25-67)98(154)122-75(30-22-44-117-106(111)112)96(152)127-80(55-69-57-118-73-28-14-13-26-72(69)73)94(150)119-59-86(141)121-77(29-15-17-40-109)104(160)136-45-23-32-85(136)103(159)130-91(66(2)3)93(110)149/h8,10-11,13-14,24-26,28,33-36,57-58,65-66,74-83,85,91,114,118,138-140H,4-7,9,12,15-23,27,29-32,37-56,59-64,109H2,1-3H3,(H2,110,149)(H,113,120)(H,115,142)(H,116,161)(H,119,150)(H,121,141)(H,122,154)(H,123,158)(H,124,151)(H,125,156)(H,126,157)(H,127,152)(H,128,153)(H,129,155)(H,130,159)(H,143,144)(H,145,146)(H,147,148)(H4,111,112,117)/t74-,75-,76-,77-,78+,79-,80-,81-,82-,83-,85-,91-,107?/m0/s1
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UniChem
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n/an/a 0.820n/an/an/an/an/an/a



The University of Iowa

Curated by ChEMBL


Assay Description
Displacement of [125I]-[Nle4-D-Phe7]-alpha-MSH from MC1R in mouse B16-F10 cells after 1.5 hrs by gamma counting


Bioorg Med Chem Lett 21: 5757-61 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.017
BindingDB Entry DOI: 10.7270/Q2H132DZ
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144524
PNG
(CHEMBL3215307 | CHEMBL410472 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CC(C)(CC(=O)N(CCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)CC(=O)NC1CCCCC1)CC(=O)N(CCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)CC(=O)NC1CCCCC1 |r|
Show InChI InChI=1S/C39H68N4O40S8/c1-39(2,17-29(46)42(19-27(44)40-23-9-5-3-6-10-23)13-15-72-37-35(82-90(66,67)68)33(80-88(60,61)62)31(78-86(54,55)56)25(76-37)21-74-84(48,49)50)18-30(47)43(20-28(45)41-24-11-7-4-8-12-24)14-16-73-38-36(83-91(69,70)71)34(81-89(63,64)65)32(79-87(57,58)59)26(77-38)22-75-85(51,52)53/h23-26,31-38H,3-22H2,1-2H3,(H,40,44)(H,41,45)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)/p-8
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n/an/an/a 1.00E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144519
PNG
(CHEMBL3215309 | CHEMBL385967 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)OC[C@@H]1O[C@H](OCCNC(=O)CN(Cc2ccccc2)C(=O)CO[C@@H]2[C@H](OS([O-])(=O)=O)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C25H38N2O38S8/c28-16(26-6-7-54-24-23(64-72(48,49)50)21(63-71(45,46)47)19(61-69(39,40)41)14(58-24)10-56-66(30,31)32)9-27(8-13-4-2-1-3-5-13)17(29)12-55-22-20(62-70(42,43)44)18(60-68(36,37)38)15(11-57-67(33,34)35)59-25(22)65-73(51,52)53/h1-5,14-15,18-25H,6-12H2,(H,26,28)(H,30,31,32)(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)/p-8
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n/an/an/a 8.50E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144523
PNG
(CHEMBL305519 | Sodium sulfated glycoconjugate deri...)
Show SMILES [O-]S(=O)(=O)OCCN(CC(=O)NC1CCCCC1)C(=O)C1OC(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O
Show InChI InChI=1S/C16H28N2O23S5/c19-10(17-9-4-2-1-3-5-9)8-18(6-7-36-42(21,22)23)15(20)13-11(38-43(24,25)26)12(39-44(27,28)29)14(40-45(30,31)32)16(37-13)41-46(33,34)35/h9,11-14,16H,1-8H2,(H,17,19)(H,21,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-5
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n/an/an/a>8.00E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144525
PNG
(CHEMBL70844 | Sodium sulfated glycoconjugate deriv...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(CC(=O)NCc1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C22H26N2O19S4/c25-16(23-11-14-7-3-1-4-8-14)13-24(12-15-9-5-2-6-10-15)21(26)19-17(40-44(27,28)29)18(41-45(30,31)32)20(42-46(33,34)35)22(39-19)43-47(36,37)38/h1-10,17-20,22H,11-13H2,(H,23,25)(H,27,28,29)(H,30,31,32)(H,33,34,35)(H,36,37,38)/p-4
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n/an/an/a 2.06E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144524
PNG
(CHEMBL3215307 | CHEMBL410472 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CC(C)(CC(=O)N(CCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)CC(=O)NC1CCCCC1)CC(=O)N(CCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)CC(=O)NC1CCCCC1 |r|
Show InChI InChI=1S/C39H68N4O40S8/c1-39(2,17-29(46)42(19-27(44)40-23-9-5-3-6-10-23)13-15-72-37-35(82-90(66,67)68)33(80-88(60,61)62)31(78-86(54,55)56)25(76-37)21-74-84(48,49)50)18-30(47)43(20-28(45)41-24-11-7-4-8-12-24)14-16-73-38-36(83-91(69,70)71)34(81-89(63,64)65)32(79-87(57,58)59)26(77-38)22-75-85(51,52)53/h23-26,31-38H,3-22H2,1-2H3,(H,40,44)(H,41,45)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)/p-8
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n/an/an/a 3.40E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144526
PNG
(CHEMBL3215304 | CHEMBL386607 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NCCO[C@H]2O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)Cc2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C26H40N2O35S7/c1-52-25-23(62-69(46,47)48)21(60-67(40,41)42)19(58-65(34,35)36)15(56-25)11-53-13-18(30)28(9-14-5-3-2-4-6-14)10-17(29)27-7-8-54-26-24(63-70(49,50)51)22(61-68(43,44)45)20(59-66(37,38)39)16(57-26)12-55-64(31,32)33/h2-6,15-16,19-26H,7-13H2,1H3,(H,27,29)(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)/p-7
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n/an/an/a 4.84E+3n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144527
PNG
(CHEMBL308220 | CHEMBL3215305 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NC2CCCCC2)Cc2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C24H36N2O17S3/c1-38-24-23(43-46(35,36)37)22(42-45(32,33)34)21(41-44(29,30)31)18(40-24)14-39-15-20(28)26(12-16-8-4-2-5-9-16)13-19(27)25-17-10-6-3-7-11-17/h2,4-5,8-9,17-18,21-24H,3,6-7,10-15H2,1H3,(H,25,27)(H,29,30,31)(H,32,33,34)(H,35,36,37)/p-3
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n/an/an/a 2.60E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144528
PNG
(CHEMBL3215306 | CHEMBL430625 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CCS([O-])(=O)=O)CC(=O)NC2CCCCC2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C19H34N2O20S4/c1-36-19-18(41-45(33,34)35)17(40-44(30,31)32)16(39-43(27,28)29)13(38-19)10-37-11-15(23)21(7-8-42(24,25)26)9-14(22)20-12-5-3-2-4-6-12/h12-13,16-19H,2-11H2,1H3,(H,20,22)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4
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n/an/an/a 5.51E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144521
PNG
(CHEMBL3215303 | CHEMBL408602 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NC2CCCCC2)[C@H]2CC[C@@H](CC2)N(CC(=O)NC2CCCCC2)C(=O)COC[C@@H]2O[C@H](OC)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r,wU:27.21,10.4,8.1,72.70,60.57,84.83,wD:30.28,78.76,49.45,51.48,54.51,66.64,(18.06,,;19.93,,;,-13.82,;1.87,-13.82,;3.74,-13.82,;,-16.9,;.83,7.89,;-.17,9.05,;-1.69,8.76,;-2.19,7.31,;-3.7,7.02,;-4.21,5.56,;-3.2,4.4,;-3.7,2.94,;-2.69,1.78,;-1.18,2.07,;-3.2,.32,;-4.71,.03,;-5.72,1.2,;-5.21,2.65,;-7.23,.9,;-8.24,2.07,;-9.75,1.78,;-10.76,2.94,;-10.26,4.4,;-8.74,4.69,;-7.74,3.52,;-2.19,-.84,;-.68,-.55,;.33,-1.72,;-.17,-3.17,;-1.69,-3.46,;-2.69,-2.3,;.83,-4.33,;.33,-5.79,;-1.18,-6.08,;-2.19,-4.92,;-1.69,-7.54,;-3.2,-7.83,;-3.7,-9.28,;-5.21,-9.57,;-6.22,-8.41,;-5.72,-6.95,;-4.21,-6.66,;2.35,-4.04,;2.85,-2.59,;3.35,-5.21,;4.87,-4.92,;5.87,-6.08,;7.39,-5.79,;7.89,-4.33,;9.4,-4.04,;9.91,-2.59,;8.9,-1.42,;10.41,-5.21,;11.92,-4.92,;12.43,-3.46,;10.97,-2.96,;12.93,-2.01,;13.88,-3.97,;9.91,-6.66,;10.92,-7.83,;10.41,-9.28,;11.87,-9.79,;8.96,-8.78,;9.91,-10.74,;8.4,-6.95,;7.89,-8.41,;6.38,-8.7,;4.87,-8.99,;6.09,-7.19,;6.67,-10.21,;-4.71,8.18,;-6.22,7.89,;-6.73,6.43,;-7.23,4.98,;-8.18,6.94,;-5.27,5.93,;-4.21,9.64,;-5.21,10.8,;-6.73,10.51,;-6.44,9,;-7.02,12.02,;-8.24,10.22,;-2.69,9.93,;-2.19,11.38,;-3.2,12.55,;-2.03,13.55,;-4.36,11.54,;-4.21,13.71,)|
Show InChI InChI=1S/C40H68N4O34S6/c1-67-39-37(77-83(61,62)63)35(75-81(55,56)57)33(73-79(49,50)51)27(71-39)19-69-21-31(47)43(17-29(45)41-23-9-5-3-6-10-23)25-13-15-26(16-14-25)44(18-30(46)42-24-11-7-4-8-12-24)32(48)22-70-20-28-34(74-80(52,53)54)36(76-82(58,59)60)38(40(68-2)72-28)78-84(64,65)66/h23-28,33-40H,3-22H2,1-2H3,(H,41,45)(H,42,46)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)/p-6
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n/an/an/a 2.79E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144527
PNG
(CHEMBL308220 | CHEMBL3215305 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NC2CCCCC2)Cc2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C24H36N2O17S3/c1-38-24-23(43-46(35,36)37)22(42-45(32,33)34)21(41-44(29,30)31)18(40-24)14-39-15-20(28)26(12-16-8-4-2-5-9-16)13-19(27)25-17-10-6-3-7-11-17/h2,4-5,8-9,17-18,21-24H,3,6-7,10-15H2,1H3,(H,25,27)(H,29,30,31)(H,32,33,34)(H,35,36,37)/p-3
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Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144529
PNG
(CHEMBL70718 | Sodium sulfated glycoconjugate deriv...)
Show SMILES OC1C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)OC1C(=O)N(CC(=O)NC1CCCCC1)Cc1ccccc1
Show InChI InChI=1S/C21H30N2O16S3/c24-15(22-14-9-5-2-6-10-14)12-23(11-13-7-3-1-4-8-13)20(26)18-16(25)17(37-40(27,28)29)19(38-41(30,31)32)21(36-18)39-42(33,34)35/h1,3-4,7-8,14,16-19,21,25H,2,5-6,9-12H2,(H,22,24)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-3
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n/an/an/a 1.16E+6n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144525
PNG
(CHEMBL70844 | Sodium sulfated glycoconjugate deriv...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(CC(=O)NCc1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C22H26N2O19S4/c25-16(23-11-14-7-3-1-4-8-14)13-24(12-15-9-5-2-6-10-15)21(26)19-17(40-44(27,28)29)18(41-45(30,31)32)20(42-46(33,34)35)22(39-19)43-47(36,37)38/h1-10,17-20,22H,11-13H2,(H,23,25)(H,27,28,29)(H,30,31,32)(H,33,34,35)(H,36,37,38)/p-4
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n/an/an/a 1.04E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144522
PNG
(CHEMBL3215308 | CHEMBL430983 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N(CC(=O)NCCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C19H28N2O20S4/c1-12(22)21(9-13-5-3-2-4-6-13)10-15(23)20-7-8-36-19-18(41-45(33,34)35)17(40-44(30,31)32)16(39-43(27,28)29)14(38-19)11-37-42(24,25)26/h2-6,14,16-19H,7-11H2,1H3,(H,20,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4
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n/an/an/a 2.87E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144520
PNG
(CHEMBL308715 | Sodium sulfated glycoconjugate deri...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1ccccc1
Show InChI InChI=1S/C27H34N2O19S4/c30-25(28-19-14-8-3-9-15-19)20(18-12-6-2-7-13-18)29(16-17-10-4-1-5-11-17)26(31)23-21(45-49(32,33)34)22(46-50(35,36)37)24(47-51(38,39)40)27(44-23)48-52(41,42)43/h1-2,4-7,10-13,19-24,27H,3,8-9,14-16H2,(H,28,30)(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)/p-4
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n/an/an/a>8.00E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay (No binding)


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50143026
PNG
((6-{benzyl[(cyclohexylcarbamoyl)methyl]carbamoyl}-...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(CC(=O)NC1CCCCC1)Cc1ccccc1
Show InChI InChI=1S/C21H30N2O19S4/c24-15(22-14-9-5-2-6-10-14)12-23(11-13-7-3-1-4-8-13)20(25)18-16(39-43(26,27)28)17(40-44(29,30)31)19(41-45(32,33)34)21(38-18)42-46(35,36)37/h1,3-4,7-8,14,16-19,21H,2,5-6,9-12H2,(H,22,24)(H,26,27,28)(H,29,30,31)(H,32,33,34)(H,35,36,37)/p-4
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n/an/an/a 1.22E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50143026
PNG
((6-{benzyl[(cyclohexylcarbamoyl)methyl]carbamoyl}-...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(CC(=O)NC1CCCCC1)Cc1ccccc1
Show InChI InChI=1S/C21H30N2O19S4/c24-15(22-14-9-5-2-6-10-14)12-23(11-13-7-3-1-4-8-13)20(25)18-16(39-43(26,27)28)17(40-44(29,30)31)19(41-45(32,33)34)21(38-18)42-46(35,36)37/h1,3-4,7-8,14,16-19,21H,2,5-6,9-12H2,(H,22,24)(H,26,27,28)(H,29,30,31)(H,32,33,34)(H,35,36,37)/p-4
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n/an/an/a 2.54E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144529
PNG
(CHEMBL70718 | Sodium sulfated glycoconjugate deriv...)
Show SMILES OC1C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)OC1C(=O)N(CC(=O)NC1CCCCC1)Cc1ccccc1
Show InChI InChI=1S/C21H30N2O16S3/c24-15(22-14-9-5-2-6-10-14)12-23(11-13-7-3-1-4-8-13)20(26)18-16(25)17(37-40(27,28)29)19(38-41(30,31)32)21(36-18)39-42(33,34)35/h1,3-4,7-8,14,16-19,21,25H,2,5-6,9-12H2,(H,22,24)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-3
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n/an/an/a 5.87E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144528
PNG
(CHEMBL3215306 | CHEMBL430625 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CCS([O-])(=O)=O)CC(=O)NC2CCCCC2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C19H34N2O20S4/c1-36-19-18(41-45(33,34)35)17(40-44(30,31)32)16(39-43(27,28)29)13(38-19)10-37-11-15(23)21(7-8-42(24,25)26)9-14(22)20-12-5-3-2-4-6-12/h12-13,16-19H,2-11H2,1H3,(H,20,22)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4
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n/an/an/a 2.96E+5n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Basic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144526
PNG
(CHEMBL3215304 | CHEMBL386607 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NCCO[C@H]2O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)Cc2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C26H40N2O35S7/c1-52-25-23(62-69(46,47)48)21(60-67(40,41)42)19(58-65(34,35)36)15(56-25)11-53-13-18(30)28(9-14-5-3-2-4-6-14)10-17(29)27-7-8-54-26-24(63-70(49,50)51)22(61-68(43,44)45)20(59-66(37,38)39)16(57-26)12-55-64(31,32)33/h2-6,15-16,19-26H,7-13H2,1H3,(H,27,29)(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)/p-7
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n/an/an/a 1.60E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 2 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144521
PNG
(CHEMBL3215303 | CHEMBL408602 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@@H](COCC(=O)N(CC(=O)NC2CCCCC2)[C@H]2CC[C@@H](CC2)N(CC(=O)NC2CCCCC2)C(=O)COC[C@@H]2O[C@H](OC)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O |r,wU:27.21,10.4,8.1,72.70,60.57,84.83,wD:30.28,78.76,49.45,51.48,54.51,66.64,(18.06,,;19.93,,;,-13.82,;1.87,-13.82,;3.74,-13.82,;,-16.9,;.83,7.89,;-.17,9.05,;-1.69,8.76,;-2.19,7.31,;-3.7,7.02,;-4.21,5.56,;-3.2,4.4,;-3.7,2.94,;-2.69,1.78,;-1.18,2.07,;-3.2,.32,;-4.71,.03,;-5.72,1.2,;-5.21,2.65,;-7.23,.9,;-8.24,2.07,;-9.75,1.78,;-10.76,2.94,;-10.26,4.4,;-8.74,4.69,;-7.74,3.52,;-2.19,-.84,;-.68,-.55,;.33,-1.72,;-.17,-3.17,;-1.69,-3.46,;-2.69,-2.3,;.83,-4.33,;.33,-5.79,;-1.18,-6.08,;-2.19,-4.92,;-1.69,-7.54,;-3.2,-7.83,;-3.7,-9.28,;-5.21,-9.57,;-6.22,-8.41,;-5.72,-6.95,;-4.21,-6.66,;2.35,-4.04,;2.85,-2.59,;3.35,-5.21,;4.87,-4.92,;5.87,-6.08,;7.39,-5.79,;7.89,-4.33,;9.4,-4.04,;9.91,-2.59,;8.9,-1.42,;10.41,-5.21,;11.92,-4.92,;12.43,-3.46,;10.97,-2.96,;12.93,-2.01,;13.88,-3.97,;9.91,-6.66,;10.92,-7.83,;10.41,-9.28,;11.87,-9.79,;8.96,-8.78,;9.91,-10.74,;8.4,-6.95,;7.89,-8.41,;6.38,-8.7,;4.87,-8.99,;6.09,-7.19,;6.67,-10.21,;-4.71,8.18,;-6.22,7.89,;-6.73,6.43,;-7.23,4.98,;-8.18,6.94,;-5.27,5.93,;-4.21,9.64,;-5.21,10.8,;-6.73,10.51,;-6.44,9,;-7.02,12.02,;-8.24,10.22,;-2.69,9.93,;-2.19,11.38,;-3.2,12.55,;-2.03,13.55,;-4.36,11.54,;-4.21,13.71,)|
Show InChI InChI=1S/C40H68N4O34S6/c1-67-39-37(77-83(61,62)63)35(75-81(55,56)57)33(73-79(49,50)51)27(71-39)19-69-21-31(47)43(17-29(45)41-23-9-5-3-6-10-23)25-13-15-26(16-14-25)44(18-30(46)42-24-11-7-4-8-12-24)32(48)22-70-20-28-34(74-80(52,53)54)36(76-82(58,59)60)38(40(68-2)72-28)78-84(64,65)66/h23-28,33-40H,3-22H2,1-2H3,(H,41,45)(H,42,46)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)/p-6
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n/an/an/a 3.26E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144523
PNG
(CHEMBL305519 | Sodium sulfated glycoconjugate deri...)
Show SMILES [O-]S(=O)(=O)OCCN(CC(=O)NC1CCCCC1)C(=O)C1OC(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O
Show InChI InChI=1S/C16H28N2O23S5/c19-10(17-9-4-2-1-3-5-9)8-18(6-7-36-42(21,22)23)15(20)13-11(38-43(24,25)26)12(39-44(27,28)29)14(40-45(30,31)32)16(37-13)41-46(33,34)35/h9,11-14,16H,1-8H2,(H,17,19)(H,21,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-5
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n/an/an/a 2.34E+6n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144520
PNG
(CHEMBL308715 | Sodium sulfated glycoconjugate deri...)
Show SMILES [O-]S(=O)(=O)OC1OC(C(OS([O-])(=O)=O)C(OS([O-])(=O)=O)C1OS([O-])(=O)=O)C(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1ccccc1
Show InChI InChI=1S/C27H34N2O19S4/c30-25(28-19-14-8-3-9-15-19)20(18-12-6-2-7-13-18)29(16-17-10-4-1-5-11-17)26(31)23-21(45-49(32,33)34)22(46-50(35,36)37)24(47-51(38,39)40)27(44-23)48-52(41,42)43/h1-2,4-7,10-13,19-24,27H,3,8-9,14-16H2,(H,28,30)(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)/p-4
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n/an/an/a 6.25E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144519
PNG
(CHEMBL3215309 | CHEMBL385967 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)OC[C@@H]1O[C@H](OCCNC(=O)CN(Cc2ccccc2)C(=O)CO[C@@H]2[C@H](OS([O-])(=O)=O)O[C@H](COS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r|
Show InChI InChI=1S/C25H38N2O38S8/c28-16(26-6-7-54-24-23(64-72(48,49)50)21(63-71(45,46)47)19(61-69(39,40)41)14(58-24)10-56-66(30,31)32)9-27(8-13-4-2-1-3-5-13)17(29)12-55-22-20(62-70(42,43)44)18(60-68(36,37)38)15(11-57-67(33,34)35)59-25(22)65-73(51,52)53/h1-5,14-15,18-25H,6-12H2,(H,26,28)(H,30,31,32)(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)/p-8
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n/an/an/a 6.36E+3n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair
Acidic fibroblast growth factor


(Homo sapiens (Human))
BDBM50144522
PNG
(CHEMBL3215308 | CHEMBL430983 | Sodium sulfated gly...)
Show SMILES [Na+].[Na+].[Na+].[Na+].CC(=O)N(CC(=O)NCCO[C@H]1O[C@@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@H]1OS([O-])(=O)=O)Cc1ccccc1 |r|
Show InChI InChI=1S/C19H28N2O20S4/c1-12(22)21(9-13-5-3-2-4-6-13)10-15(23)20-7-8-36-19-18(41-45(33,34)35)17(40-44(30,31)32)16(39-43(27,28)29)14(38-19)11-37-42(24,25)26/h2-6,14,16-19H,7-11H2,1H3,(H,20,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4
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n/an/an/a 3.43E+4n/an/an/an/an/a



Progen Industries Ltd

Curated by ChEMBL


Assay Description
Binding affinity for human fibroblast growth factor 1 in surface plasmon resonance (SPR) assay


Bioorg Med Chem Lett 14: 2221-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.017
BindingDB Entry DOI: 10.7270/Q2M9084D
More data for this
Ligand-Target Pair