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Compile Data Set for Download or QSAR

Found 89 hits with Last Name = 'salvagno' and Initial = 'c'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxytocin receptor


(HEK293)
BDBM50326715
PNG
(CHEMBL456263 | N-(6-methoxypyridin-3-yl)-1,2-dimet...)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)c(C)n1
Show InChI InChI=1S/C24H25N5O3S/c1-17-7-5-6-8-22(17)19-9-10-20(25-13-19)15-29(21-11-12-23(32-4)26-14-21)33(30,31)24-16-28(3)18(2)27-24/h5-14,16H,15H2,1-4H3
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0.794n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of 3H-oxytocin from human recombinant oxytocin receptor expressed in CHO cells by filtration binding assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412919
PNG
(CHEMBL475395)
Show SMILES Cc1cc(ccc1-c1ccccc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C23H27NO2/c1-17-14-20(11-12-22(17)19-6-3-2-4-7-19)23(25)24(15-18-9-10-18)16-21-8-5-13-26-21/h2-4,6-7,11-12,14,18,21H,5,8-10,13,15-16H2,1H3
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0.794n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412919
PNG
(CHEMBL475395)
Show SMILES Cc1cc(ccc1-c1ccccc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C23H27NO2/c1-17-14-20(11-12-22(17)19-6-3-2-4-7-19)23(25)24(15-18-9-10-18)16-21-8-5-13-26-21/h2-4,6-7,11-12,14,18,21H,5,8-10,13,15-16H2,1H3
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1.26n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cells by filtration binding assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413725
PNG
(CHEMBL456254)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C27H27N3O5S/c1-19-7-5-6-8-24(19)20-9-10-21(28-16-20)18-30(22-11-14-27(35-4)29-17-22)36(31,32)26-15-23(33-2)12-13-25(26)34-3/h5-17H,18H2,1-4H3
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1.58n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413714
PNG
(CHEMBL458635)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C26H25N3O4S/c1-19-6-4-5-7-25(19)20-8-9-21(27-16-20)18-29(22-10-15-26(33-3)28-17-22)34(30,31)24-13-11-23(32-2)12-14-24/h4-17H,18H2,1-3H3
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2n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413716
PNG
(CHEMBL456464)
Show SMILES COc1ccc(c(OC)c1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C27H27N3O5S/c1-19-7-5-6-8-24(19)20-9-10-21(28-16-20)18-30(22-11-14-27(35-4)29-17-22)36(31,32)26-13-12-23(33-2)15-25(26)34-3/h5-17H,18H2,1-4H3
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2.51n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412936
PNG
(CHEMBL481569)
Show SMILES Cc1cc(F)ccc1-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C23H26FNO2/c1-16-13-20(24)10-11-22(16)18-6-8-19(9-7-18)23(26)25(14-17-4-5-17)15-21-3-2-12-27-21/h6-11,13,17,21H,2-5,12,14-15H2,1H3
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3.16n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413713
PNG
(CHEMBL458634)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1Cl)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22ClN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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3.16n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412915
PNG
(CHEMBL514975)
Show SMILES Clc1ccccc1-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C22H24ClNO2/c23-21-6-2-1-5-20(21)17-9-11-18(12-10-17)22(25)24(14-16-7-8-16)15-19-4-3-13-26-19/h1-2,5-6,9-12,16,19H,3-4,7-8,13-15H2
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3.16n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413717
PNG
(CHEMBL515818)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C24H22N4O3S/c1-18-7-3-4-8-22(18)19-10-11-20(26-15-19)17-28(21-12-13-23(31-2)27-16-21)32(29,30)24-9-5-6-14-25-24/h3-16H,17H2,1-2H3
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3.98n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413712
PNG
(CHEMBL515660)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C#N)c1ccc(OC)nc1
Show InChI InChI=1S/C26H22N4O4S/c1-33-23-10-12-24(13-11-23)35(31,32)30(22-9-14-26(34-2)29-17-22)18-21-8-7-20(16-28-21)25-6-4-3-5-19(25)15-27/h3-14,16-17H,18H2,1-2H3
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6.31n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413718
PNG
(CHEMBL514586)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C26H25N3O5S2/c1-19-6-4-5-7-25(19)20-8-9-21(27-16-20)18-29(22-10-15-26(34-2)28-17-22)36(32,33)24-13-11-23(12-14-24)35(3,30)31/h4-17H,18H2,1-3H3
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6.31n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413715
PNG
(CHEMBL457544)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1F)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22FN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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6.31n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50205990
PNG
(CHEMBL395429 | OXYTOCIN)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O |r|
Show InChI InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1
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6.80n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to oxytocin receptor


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413714
PNG
(CHEMBL458635)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C26H25N3O4S/c1-19-6-4-5-7-25(19)20-8-9-21(27-16-20)18-29(22-10-15-26(33-3)28-17-22)34(30,31)24-13-11-23(32-2)12-14-24/h4-17H,18H2,1-3H3
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7.94n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412921
PNG
(CHEMBL473442)
Show SMILES Clc1cccc(c1)-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C22H24ClNO2/c23-20-4-1-3-19(13-20)17-8-10-18(11-9-17)22(25)24(14-16-6-7-16)15-21-5-2-12-26-21/h1,3-4,8-11,13,16,21H,2,5-7,12,14-15H2
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7.94n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413715
PNG
(CHEMBL457544)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1F)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22FN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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7.94n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413719
PNG
(CHEMBL457998)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H23N3O3S/c1-19-8-6-7-11-24(19)20-12-13-21(26-16-20)18-28(22-14-15-25(31-2)27-17-22)32(29,30)23-9-4-3-5-10-23/h3-17H,18H2,1-2H3
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10n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413712
PNG
(CHEMBL515660)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C#N)c1ccc(OC)nc1
Show InChI InChI=1S/C26H22N4O4S/c1-33-23-10-12-24(13-11-23)35(31,32)30(22-9-14-26(34-2)29-17-22)18-21-8-7-20(16-28-21)25-6-4-3-5-19(25)15-27/h3-14,16-17H,18H2,1-2H3
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10n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413713
PNG
(CHEMBL458634)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1Cl)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22ClN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413723
PNG
(CHEMBL458872)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C26H25N3O5S2/c1-19-7-4-5-10-25(19)20-11-12-21(27-16-20)18-29(22-13-14-26(34-2)28-17-22)36(32,33)24-9-6-8-23(15-24)35(3,30)31/h4-17H,18H2,1-3H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413722
PNG
(CHEMBL458654)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H21N3O3S2/c1-17-6-3-4-7-21(17)18-9-10-19(24-14-18)16-26(20-11-12-22(29-2)25-15-20)31(27,28)23-8-5-13-30-23/h3-15H,16H2,1-2H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413721
PNG
(CHEMBL514123)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1sc(C)nc1C
Show InChI InChI=1S/C24H24N4O3S2/c1-16-7-5-6-8-22(16)19-9-10-20(25-13-19)15-28(21-11-12-23(31-4)26-14-21)33(29,30)24-17(2)27-18(3)32-24/h5-14H,15H2,1-4H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413720
PNG
(CHEMBL515975)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)cn1
Show InChI InChI=1S/C23H23N5O3S/c1-17-6-4-5-7-21(17)18-8-9-19(24-12-18)14-28(20-10-11-22(31-3)25-13-20)32(29,30)23-15-27(2)16-26-23/h4-13,15-16H,14H2,1-3H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50326715
PNG
(CHEMBL456263 | N-(6-methoxypyridin-3-yl)-1,2-dimet...)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)c(C)n1
Show InChI InChI=1S/C24H25N5O3S/c1-17-7-5-6-8-22(17)19-9-10-20(25-13-19)15-29(21-11-12-23(32-4)26-14-21)33(30,31)24-16-28(3)18(2)27-24/h5-14,16H,15H2,1-4H3
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12.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50413714
PNG
(CHEMBL458635)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C26H25N3O4S/c1-19-6-4-5-7-25(19)20-8-9-21(27-16-20)18-29(22-10-15-26(33-3)28-17-22)34(30,31)24-13-11-23(32-2)12-14-24/h4-17H,18H2,1-3H3
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15.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V1a receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412930
PNG
(CHEMBL482323)
Show SMILES Cc1cc(F)ccc1-c1ccc(cc1)C(=O)N(CC1CCCO1)Cc1ccccc1
Show InChI InChI=1S/C26H26FNO2/c1-19-16-23(27)13-14-25(19)21-9-11-22(12-10-21)26(29)28(18-24-8-5-15-30-24)17-20-6-3-2-4-7-20/h2-4,6-7,9-14,16,24H,5,8,15,17-18H2,1H3
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15.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50413713
PNG
(CHEMBL458634)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1Cl)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22ClN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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25.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V1a receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V1b receptor


(Homo sapiens (Human))
BDBM50326715
PNG
(CHEMBL456263 | N-(6-methoxypyridin-3-yl)-1,2-dimet...)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)c(C)n1
Show InChI InChI=1S/C24H25N5O3S/c1-17-7-5-6-8-22(17)19-9-10-20(25-13-19)15-29(21-11-12-23(32-4)26-14-21)33(30,31)24-16-28(3)18(2)27-24/h5-14,16H,15H2,1-4H3
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31.6n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to vasopressin V1b receptor by filtration assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413708
PNG
(CHEMBL514287)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1noc(n1)-c1ccccc1)c1ccc(OC)nc1
Show InChI InChI=1S/C22H20N4O5S/c1-29-18-9-11-19(12-10-18)32(27,28)26(17-8-13-21(30-2)23-14-17)15-20-24-22(31-25-20)16-6-4-3-5-7-16/h3-14H,15H2,1-2H3
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39.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413707
PNG
(CHEMBL515384)
Show SMILES COc1ccc(cn1)N(Cc1nc(cs1)-c1ccccc1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C21H18N4O3S2/c1-28-19-11-10-17(13-23-19)25(30(26,27)21-9-5-6-12-22-21)14-20-24-18(15-29-20)16-7-3-2-4-8-16/h2-13,15H,14H2,1H3
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39.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412929
PNG
(CHEMBL474621)
Show SMILES Cc1cc(ccc1-c1ccccc1)C(=O)N(CC1CCCO1)Cc1ccccc1
Show InChI InChI=1S/C26H27NO2/c1-20-17-23(14-15-25(20)22-11-6-3-7-12-22)26(28)27(19-24-13-8-16-29-24)18-21-9-4-2-5-10-21/h2-7,9-12,14-15,17,24H,8,13,16,18-19H2,1H3
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39.8n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412914
PNG
(CHEMBL475207)
Show SMILES O=C(N(CC1CC1)CC1CCCO1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C22H25NO2/c24-22(23(15-17-8-9-17)16-21-7-4-14-25-21)20-12-10-19(11-13-20)18-5-2-1-3-6-18/h1-3,5-6,10-13,17,21H,4,7-9,14-16H2
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50.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50413715
PNG
(CHEMBL457544)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1F)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22FN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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50.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V1a receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50413712
PNG
(CHEMBL515660)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C#N)c1ccc(OC)nc1
Show InChI InChI=1S/C26H22N4O4S/c1-33-23-10-12-24(13-11-23)35(31,32)30(22-9-14-26(34-2)29-17-22)18-21-8-7-20(16-28-21)25-6-4-3-5-19(25)15-27/h3-14,16-17H,18H2,1-2H3
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50.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V1a receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(Homo sapiens (Human))
BDBM50326715
PNG
(CHEMBL456263 | N-(6-methoxypyridin-3-yl)-1,2-dimet...)
Show SMILES COc1ccc(cn1)N(Cc1ccc(cn1)-c1ccccc1C)S(=O)(=O)c1cn(C)c(C)n1
Show InChI InChI=1S/C24H25N5O3S/c1-17-7-5-6-8-22(17)19-9-10-20(25-13-19)15-29(21-11-12-23(32-4)26-14-21)33(30,31)24-16-28(3)18(2)27-24/h5-14,16H,15H2,1-4H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to vasopressin V1a receptor by filtration assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50413715
PNG
(CHEMBL457544)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1F)c1ccc(OC)nc1
Show InChI InChI=1S/C25H22FN3O4S/c1-32-21-10-12-22(13-11-21)34(30,31)29(20-9-14-25(33-2)28-16-20)17-19-8-7-18(15-27-19)23-5-3-4-6-24(23)26/h3-16H,17H2,1-2H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V2 receptor expressed in yeast cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412931
PNG
(CHEMBL482321)
Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N(CC1CCCO1)Cc1ccccc1
Show InChI InChI=1S/C26H27NO3/c1-29-25-12-6-5-11-24(25)21-13-15-22(16-14-21)26(28)27(19-23-10-7-17-30-23)18-20-8-3-2-4-9-20/h2-6,8-9,11-16,23H,7,10,17-19H2,1H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413709
PNG
(CHEMBL459291)
Show SMILES COc1ccc(cn1)N(Cc1nc(no1)-c1ccccc1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C20H17N5O4S/c1-28-17-11-10-16(13-22-17)25(30(26,27)19-9-5-6-12-21-19)14-18-23-20(24-29-18)15-7-3-2-4-8-15/h2-13H,14H2,1H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413710
PNG
(CHEMBL514113)
Show SMILES COc1ccc(cc1)N(Cc1csc(n1)-c1ccccc1)S(=O)(=O)c1ccccn1
Show InChI InChI=1S/C22H19N3O3S2/c1-28-20-12-10-19(11-13-20)25(30(26,27)21-9-5-6-14-23-21)15-18-16-29-22(24-18)17-7-3-2-4-8-17/h2-14,16H,15H2,1H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412916
PNG
(CHEMBL515111)
Show SMILES COc1ccccc1-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C23H27NO3/c1-26-22-7-3-2-6-21(22)18-10-12-19(13-11-18)23(25)24(15-17-8-9-17)16-20-5-4-14-27-20/h2-3,6-7,10-13,17,20H,4-5,8-9,14-16H2,1H3
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63.1n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412934
PNG
(CHEMBL480546)
Show SMILES FC(F)(F)c1ccccc1-c1ccc(cn1)C(=O)N(CC1CCCO1)Cc1ccccc1
Show InChI InChI=1S/C25H23F3N2O2/c26-25(27,28)22-11-5-4-10-21(22)23-13-12-19(15-29-23)24(31)30(17-20-9-6-14-32-20)16-18-7-2-1-3-8-18/h1-5,7-8,10-13,15,20H,6,9,14,16-17H2
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79.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412922
PNG
(CHEMBL473443)
Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C22H24ClNO2/c23-20-11-9-18(10-12-20)17-5-7-19(8-6-17)22(25)24(14-16-3-4-16)15-21-2-1-13-26-21/h5-12,16,21H,1-4,13-15H2
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79.4n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413711
PNG
(CHEMBL457997)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1)c1ccc(OC)nc1
Show InChI InChI=1S/C25H23N3O4S/c1-31-23-11-13-24(14-12-23)33(29,30)28(22-10-15-25(32-2)27-17-22)18-21-9-8-20(16-26-21)19-6-4-3-5-7-19/h3-17H,18H2,1-2H3
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126n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity to human recombinant oxytocin receptor expressed in CHO cells by fluorescence polarization assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412920
PNG
(CHEMBL514031)
Show SMILES Cc1cc(ccc1C(=O)N(CC1CC1)CC1CCCO1)-c1ccccc1
Show InChI InChI=1S/C23H27NO2/c1-17-14-20(19-6-3-2-4-7-19)11-12-22(17)23(25)24(15-18-9-10-18)16-21-8-5-13-26-21/h2-4,6-7,11-12,14,18,21H,5,8-10,13,15-16H2,1H3
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126n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412926
PNG
(CHEMBL481730)
Show SMILES FC(F)(F)c1cccnc1-c1ccc(cc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C22H23F3N2O2/c23-22(24,25)19-4-1-11-26-20(19)16-7-9-17(10-8-16)21(28)27(13-15-5-6-15)14-18-3-2-12-29-18/h1,4,7-11,15,18H,2-3,5-6,12-14H2
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200n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50413724
PNG
(CHEMBL459073)
Show SMILES COc1ccc(cc1)N(Cc1cc2cccc3CCCn(c23)c1=O)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H24N2O4S/c1-32-23-14-12-22(13-15-23)28(33(30,31)24-10-3-2-4-11-24)18-21-17-20-8-5-7-19-9-6-16-27(25(19)20)26(21)29/h2-5,7-8,10-15,17H,6,9,16,18H2,1H3
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200n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50412919
PNG
(CHEMBL475395)
Show SMILES Cc1cc(ccc1-c1ccccc1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C23H27NO2/c1-17-14-20(11-12-22(17)19-6-3-2-4-7-19)23(25)24(15-18-9-10-18)16-21-8-5-13-26-21/h2-4,6-7,11-12,14,18,21H,5,8-10,13,15-16H2,1H3
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251n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]oxytocin from human vasopressin V2 receptor expressed in CHO cells by filtration binding assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
Vasopressin V2 receptor (V2)


(Homo sapiens (Human))
BDBM50413714
PNG
(CHEMBL458635)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)-c1ccccc1C)c1ccc(OC)nc1
Show InChI InChI=1S/C26H25N3O4S/c1-19-6-4-5-7-25(19)20-8-9-21(27-16-20)18-29(22-10-15-26(33-3)28-17-22)34(30,31)24-13-11-23(32-2)12-14-24/h4-17H,18H2,1-3H3
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251n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant vasopressin V2 receptor expressed in yeast cells by FLIPR assay


Bioorg Med Chem Lett 19: 528-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.018
BindingDB Entry DOI: 10.7270/Q2N29Z5F
More data for this
Ligand-Target Pair
Oxytocin receptor


(HEK293)
BDBM50412927
PNG
(CHEMBL515447)
Show SMILES FC(F)(F)c1ccccc1-c1ccc(cn1)C(=O)N(CC1CC1)CC1CCCO1
Show InChI InChI=1S/C22H23F3N2O2/c23-22(24,25)19-6-2-1-5-18(19)20-10-9-16(12-26-20)21(28)27(13-15-7-8-15)14-17-4-3-11-29-17/h1-2,5-6,9-10,12,15,17H,3-4,7-8,11,13-14H2
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316n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human oxytocin receptor expressed in CHO cells by FLIPR assay


Bioorg Med Chem Lett 19: 990-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.064
BindingDB Entry DOI: 10.7270/Q2319WTT
More data for this
Ligand-Target Pair
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