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Compile Data Set for Download or QSAR

Found 755 hits with Last Name = 'schiano moriello' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377660
PNG
(CHEMBL255904)
Show SMILES CC(C)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H20N4/c1-14(2)13-22-20-18(19-21-22)12-15-8-10-17(11-9-15)16-6-4-3-5-7-16/h3-11,14H,12-13H2,1-2H3
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1.60E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377660
PNG
(CHEMBL255904)
Show SMILES CC(C)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H20N4/c1-14(2)13-22-20-18(19-21-22)12-15-8-10-17(11-9-15)16-6-4-3-5-7-16/h3-11,14H,12-13H2,1-2H3
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4.70E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377661
PNG
(CHEMBL403167)
Show SMILES CC(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C17H16N4O/c1-13(22)12-21-19-17(18-20-21)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10H,11-12H2,1H3
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5.20E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377658
PNG
(CHEMBL257157)
Show SMILES N#CCn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C16H13N5/c17-10-11-21-19-16(18-20-21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,11-12H2
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6.20E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377672
PNG
(CHEMBL255903)
Show SMILES CC(C)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H20N4/c1-14(2)13-22-18(19-20-21-22)12-15-8-10-17(11-9-15)16-6-4-3-5-7-16/h3-11,14H,12-13H2,1-2H3
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7.70E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377669
PNG
(CHEMBL258164)
Show SMILES COC(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C17H16N4O2/c1-23-17(22)12-21-19-16(18-20-21)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3
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8.10E+3n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377658
PNG
(CHEMBL257157)
Show SMILES N#CCn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C16H13N5/c17-10-11-21-19-16(18-20-21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,11-12H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377659
PNG
(CHEMBL404652)
Show SMILES N#CCn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C16H13N5/c17-10-11-21-16(18-19-20-21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,11-12H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377672
PNG
(CHEMBL255903)
Show SMILES CC(C)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H20N4/c1-14(2)13-22-18(19-20-21-22)12-15-8-10-17(11-9-15)16-6-4-3-5-7-16/h3-11,14H,12-13H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377661
PNG
(CHEMBL403167)
Show SMILES CC(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C17H16N4O/c1-13(22)12-21-19-17(18-20-21)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377670
PNG
(CHEMBL254788)
Show SMILES CN(C)C(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H19N5O/c1-22(2)18(24)13-23-20-17(19-21-23)12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11H,12-13H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377673
PNG
(CHEMBL257961)
Show SMILES COC(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H17N5O3/c1-26-17(24)12-23-21-16(20-22-23)11-19-18(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377663
PNG
(CHEMBL257548)
Show SMILES COC(=O)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H17N5O3/c1-26-17(24)12-23-16(20-21-22-23)11-19-18(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377674
PNG
(CHEMBL257569)
Show SMILES O=C(NCc1nnnn1CC#N)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H14N6O/c18-10-11-23-16(20-21-22-23)12-19-17(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9H,11-12H2,(H,19,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377665
PNG
(CHEMBL257777)
Show SMILES CC(C)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C19H21N5O/c1-14(2)13-24-22-18(21-23-24)12-20-19(25)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14H,12-13H2,1-2H3,(H,20,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377673
PNG
(CHEMBL257961)
Show SMILES COC(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H17N5O3/c1-26-17(24)12-23-21-16(20-22-23)11-19-18(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377674
PNG
(CHEMBL257569)
Show SMILES O=C(NCc1nnnn1CC#N)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H14N6O/c18-10-11-23-16(20-21-22-23)12-19-17(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9H,11-12H2,(H,19,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377667
PNG
(CHEMBL257778)
Show SMILES CC(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H17N5O2/c1-13(24)12-23-21-17(20-22-23)11-19-18(25)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377657
PNG
(CHEMBL258163)
Show SMILES COC(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O2/c1-23-17(22)12-21-16(18-19-20-21)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377662
PNG
(CHEMBL404541)
Show SMILES CC(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c1-13(22)12-21-17(18-19-20-21)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377664
PNG
(CHEMBL402283)
Show SMILES O=C(NCc1nnn(CC#N)n1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H14N6O/c18-10-11-23-21-16(20-22-23)12-19-17(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9H,11-12H2,(H,19,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377675
PNG
(CHEMBL404542)
Show SMILES CN(C)C(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H19N5O/c1-22(2)18(24)13-23-17(19-20-21-23)12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11H,12-13H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377675
PNG
(CHEMBL404542)
Show SMILES CN(C)C(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H19N5O/c1-22(2)18(24)13-23-17(19-20-21-23)12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11H,12-13H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377662
PNG
(CHEMBL404541)
Show SMILES CC(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c1-13(22)12-21-17(18-19-20-21)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377670
PNG
(CHEMBL254788)
Show SMILES CN(C)C(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H19N5O/c1-22(2)18(24)13-23-20-17(19-21-23)12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11H,12-13H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377666
PNG
(CHEMBL257570)
Show SMILES CC(C)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C19H21N5O/c1-14(2)13-24-18(21-22-23-24)12-20-19(25)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14H,12-13H2,1-2H3,(H,20,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377667
PNG
(CHEMBL257778)
Show SMILES CC(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C18H17N5O2/c1-13(24)12-23-21-17(20-22-23)11-19-18(25)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377671
PNG
(CHEMBL403221)
Show SMILES CC(=O)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H17N5O2/c1-13(24)12-23-17(20-21-22-23)11-19-18(25)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377668
PNG
(CHEMBL258162)
Show SMILES CN(C)C(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C19H20N6O2/c1-24(2)18(26)13-25-22-17(21-23-25)12-20-19(27)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11H,12-13H2,1-2H3,(H,20,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377657
PNG
(CHEMBL258163)
Show SMILES COC(=O)Cn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O2/c1-23-17(22)12-21-16(18-19-20-21)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50377659
PNG
(CHEMBL404652)
Show SMILES N#CCn1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C16H13N5/c17-10-11-21-16(18-19-20-21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9H,11-12H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377669
PNG
(CHEMBL258164)
Show SMILES COC(=O)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C17H16N4O2/c1-23-17(22)12-21-19-16(18-20-21)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377668
PNG
(CHEMBL258162)
Show SMILES CN(C)C(=O)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C19H20N6O2/c1-24(2)18(26)13-25-22-17(21-23-25)12-20-19(27)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11H,12-13H2,1-2H3,(H,20,27)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377671
PNG
(CHEMBL403221)
Show SMILES CC(=O)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H17N5O2/c1-13(24)12-23-17(20-21-22-23)11-19-18(25)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377666
PNG
(CHEMBL257570)
Show SMILES CC(C)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C19H21N5O/c1-14(2)13-24-18(21-22-23-24)12-20-19(25)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14H,12-13H2,1-2H3,(H,20,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377665
PNG
(CHEMBL257777)
Show SMILES CC(C)Cn1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C19H21N5O/c1-14(2)13-24-22-18(21-23-24)12-20-19(25)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14H,12-13H2,1-2H3,(H,20,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377663
PNG
(CHEMBL257548)
Show SMILES COC(=O)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H17N5O3/c1-26-17(24)12-23-16(20-21-22-23)11-19-18(25)15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-10H,11-12H2,1H3,(H,19,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50377664
PNG
(CHEMBL402283)
Show SMILES O=C(NCc1nnn(CC#N)n1)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H14N6O/c18-10-11-23-21-16(20-22-23)12-19-17(24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9H,11-12H2,(H,19,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor expressed in COS cells


Bioorg Med Chem Lett 18: 2820-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.003
BindingDB Entry DOI: 10.7270/Q22808H1
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432910
PNG
(CHEMBL2376864)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1cccc(O)c1
Show InChI InChI=1S/C17H17N5O2/c1-21(2)17(24)22-16(18-19-20-22)10-12-6-8-13(9-7-12)14-4-3-5-15(23)11-14/h3-9,11,23H,10H2,1-2H3
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n/an/a 3n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432901
PNG
(CHEMBL2376851)
Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2ccc(O)cc2)n1
Show InChI InChI=1S/C17H17N5O2/c1-21(2)17(24)22-19-16(18-20-22)11-12-3-5-13(6-4-12)14-7-9-15(23)10-8-14/h3-10,23H,11H2,1-2H3
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n/an/a 5.40n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432923
PNG
(CHEMBL2376869)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccc(C)cc1
Show InChI InChI=1S/C18H19N5O/c1-13-4-8-15(9-5-13)16-10-6-14(7-11-16)12-17-19-20-21-23(17)18(24)22(2)3/h4-11H,12H2,1-3H3
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Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432900
PNG
(CHEMBL2376852)
Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1
Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)
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Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432904
PNG
(CHEMBL2376848)
Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2ccc(CO)cc2)n1
Show InChI InChI=1S/C18H19N5O2/c1-22(2)18(25)23-20-17(19-21-23)11-13-3-7-15(8-4-13)16-9-5-14(12-24)6-10-16/h3-10,24H,11-12H2,1-2H3
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Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432924
PNG
(CHEMBL2376868)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1cccc(C)c1
Show InChI InChI=1S/C18H19N5O/c1-13-5-4-6-16(11-13)15-9-7-14(8-10-15)12-17-19-20-21-23(17)18(24)22(2)3/h4-11H,12H2,1-3H3
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UniChem
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n/an/a 9.70n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Homo sapiens (Human))
BDBM50432902
PNG
(CHEMBL2376850)
Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(O)c2)n1
Show InChI InChI=1S/C17H17N5O2/c1-21(2)17(24)22-19-16(18-20-22)10-12-6-8-13(9-7-12)14-4-3-5-15(23)11-14/h3-9,11,23H,10H2,1-2H3
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antibodypedia
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n/an/a 10n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of MAGL (unknown origin) expressed in African green monkey COS7 cell cytosolic fraction assessed as [3H]2-AG hydrolysis to [3H]arachidonic...


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432905
PNG
(CHEMBL2376847)
Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(CO)c2)n1
Show InChI InChI=1S/C18H19N5O2/c1-22(2)18(25)23-20-17(19-21-23)11-13-6-8-15(9-7-13)16-5-3-4-14(10-16)12-24/h3-10,24H,11-12H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432913
PNG
(CHEMBL2376861)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1cccc(CO)c1
Show InChI InChI=1S/C18H19N5O2/c1-22(2)18(25)23-17(19-20-21-23)11-13-6-8-15(9-7-13)16-5-3-4-14(10-16)12-24/h3-10,24H,11-12H2,1-2H3
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n/an/a 11n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432908
PNG
(CHEMBL2376866)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1cccc(c1)C(N)=O
Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-16(20-21-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)
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n/an/a 11n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432906
PNG
(CHEMBL2376846)
Show SMILES COC(=O)c1cccc(c1)-c1ccc(Cc2nnn(n2)C(=O)N(C)C)cc1
Show InChI InChI=1S/C19H19N5O3/c1-23(2)19(26)24-21-17(20-22-24)11-13-7-9-14(10-8-13)15-5-4-6-16(12-15)18(25)27-3/h4-10,12H,11H2,1-3H3
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n/an/a 12n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
Anandamide amidohydrolase


(Rattus norvegicus (rat))
BDBM50432921
PNG
(CHEMBL2376843)
Show SMILES CN(CCCCc1ccccc1)C(=O)n1nnc(Cc2ccc(cc2)-c2ccccc2)n1
Show InChI InChI=1S/C26H27N5O/c1-30(19-9-8-12-21-10-4-2-5-11-21)26(32)31-28-25(27-29-31)20-22-15-17-24(18-16-22)23-13-6-3-7-14-23/h2-7,10-11,13-18H,8-9,12,19-20H2,1H3
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n/an/a 12n/an/an/an/an/an/a



Sapienza Universit£ di Roma

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis


Eur J Med Chem 63: 118-32 (2013)


Article DOI: 10.1016/j.ejmech.2013.02.005
BindingDB Entry DOI: 10.7270/Q2K64KFB
More data for this
Ligand-Target Pair
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