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Compile Data Set for Download or QSAR

Found 182 hits with Last Name = 'segreti' and Initial = 'ja'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50409919
PNG
(CHEMBL12282)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC2CC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(F)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C47H69ClFN3O13/c1-12-35-47(9)39(51(43(56)65-47)18-17-30-15-16-33(49)32(48)20-30)27(5)36(53)24(2)21-46(8,59-11)40(64-42-37(54)34(19-26(4)61-42)50(10)22-31-13-14-31)28(6)38(29(7)41(55)62-35)63-45(58)52-25(3)23-60-44(52)57/h15-16,20,24-29,31,34-35,37-40,42,54H,12-14,17-19,21-23H2,1-11H3/t24-,25+,26-,27+,28+,29-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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0.110n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50409920
PNG
(CHEMBL273440)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(C)C)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C46H69Cl2N3O13/c1-14-34-46(11)38(50(42(55)64-46)18-17-30-15-16-31(47)32(48)20-30)27(7)35(52)24(4)21-45(10,58-13)39(63-41-36(53)33(19-26(6)60-41)49(12)23(2)3)28(8)37(29(9)40(54)61-34)62-44(57)51-25(5)22-59-43(51)56/h15-16,20,23-29,33-34,36-39,41,53H,14,17-19,21-22H2,1-13H3/t24-,25+,26-,27+,28+,29-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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0.230n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50409919
PNG
(CHEMBL12282)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC2CC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(F)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C47H69ClFN3O13/c1-12-35-47(9)39(51(43(56)65-47)18-17-30-15-16-33(49)32(48)20-30)27(5)36(53)24(2)21-46(8,59-11)40(64-42-37(54)34(19-26(4)61-42)50(10)22-31-13-14-31)28(6)38(29(7)41(55)62-35)63-45(58)52-25(3)23-60-44(52)57/h15-16,20,24-29,31,34-35,37-40,42,54H,12-14,17-19,21-23H2,1-11H3/t24-,25+,26-,27+,28+,29-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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0.330n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50409921
PNG
(CHEMBL429956)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC2CC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C47H69Cl2N3O13/c1-12-35-47(9)39(51(43(56)65-47)18-17-30-15-16-32(48)33(49)20-30)27(5)36(53)24(2)21-46(8,59-11)40(64-42-37(54)34(19-26(4)61-42)50(10)22-31-13-14-31)28(6)38(29(7)41(55)62-35)63-45(58)52-25(3)23-60-44(52)57/h15-16,20,24-29,31,34-35,37-40,42,54H,12-14,17-19,21-23H2,1-11H3/t24-,25+,26-,27+,28+,29-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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0.680n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50409918
PNG
(CHEMBL275935)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)C2CCCC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C48H71Cl2N3O13/c1-12-36-48(9)40(52(44(57)66-48)20-19-31-17-18-33(49)34(50)22-31)28(5)37(54)25(2)23-47(8,60-11)41(65-43-38(55)35(21-27(4)62-43)51(10)32-15-13-14-16-32)29(6)39(30(7)42(56)63-36)64-46(59)53-26(3)24-61-45(53)58/h17-18,22,25-30,32,35-36,38-41,43,55H,12-16,19-21,23-24H2,1-11H3/t25-,26+,27-,28+,29+,30-,35+,36-,38-,39+,40-,41-,43?,47+,48-/m1/s1
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0.690n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001560
PNG
(CHEMBL273275)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C3CCCC3)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C48H72ClN3O13/c1-12-36-48(9)40(51(44(56)65-48)22-21-32-17-19-33(49)20-18-32)29(5)37(53)26(2)24-47(8,59-11)41(64-43-38(54)35(23-28(4)61-43)50(10)34-15-13-14-16-34)30(6)39(31(7)42(55)62-36)63-46(58)52-27(3)25-60-45(52)57/h17-20,26-31,34-36,38-41,43,54H,12-16,21-25H2,1-11H3/t26-,27+,28-,29+,30+,31-,35+,36-,38-,39+,40-,41-,43?,47+,48-/m1/s1
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1.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50409921
PNG
(CHEMBL429956)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)CC2CC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C47H69Cl2N3O13/c1-12-35-47(9)39(51(43(56)65-47)18-17-30-15-16-32(48)33(49)20-30)27(5)36(53)24(2)21-46(8,59-11)40(64-42-37(54)34(19-26(4)61-42)50(10)22-31-13-14-31)28(6)38(29(7)41(55)62-35)63-45(58)52-25(3)23-60-44(52)57/h15-16,20,24-29,31,34-35,37-40,42,54H,12-14,17-19,21-23H2,1-11H3/t24-,25+,26-,27+,28+,29-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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1.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001571
PNG
(CHEMBL273466)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H68ClN3O13/c1-13-33-45(10)37(48(43(55)62-45)19-18-30-14-16-31(46)17-15-30)27(6)34(50)25(4)23-44(9,56-12)38(61-40-35(51)32(22-26(5)58-40)47(11)24(2)3)28(7)36(29(8)39(52)59-33)60-42(54)49-20-21-57-41(49)53/h14-17,24-29,32-33,35-38,40,51H,13,18-23H2,1-12H3/t25-,26-,27+,28+,29-,32+,33-,35-,36+,37-,38-,40?,44+,45-/m1/s1
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2.10n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001563
PNG
(CHEMBL273535)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)[C@@H](C)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-15-35-47(12)39(50(43(55)64-47)21-20-32-16-18-33(48)19-17-32)27(6)36(52)25(4)23-46(11,58-14)40(63-42-37(53)34(22-26(5)59-42)49(13)24(2)3)28(7)38(29(8)41(54)61-35)62-45(57)51-30(9)31(10)60-44(51)56/h16-19,24-31,34-35,37-40,42,53H,15,20-23H2,1-14H3/t25-,26-,27+,28+,29-,30+,31-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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2.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001566
PNG
(CHEMBL275467)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(42(54)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-27(6)59-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-44(56)50-26(5)23-58-43(50)55/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26+,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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2.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001573
PNG
(CHEMBL273387)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C49H79ClN2O13/c1-16-36-49(12)41(52(46(57)65-49)22-21-33-17-19-34(50)20-18-33)29(6)38(53)27(4)24-48(11,59-15)43(64-45-39(54)35(23-28(5)60-45)51(13)26(2)3)30(7)40(31(8)44(56)62-36)63-37-25-47(10,58-14)42(55)32(9)61-37/h17-20,26-32,35-37,39-43,45,54-55H,16,21-25H2,1-15H3/t27-,28-,29+,30+,31-,32+,35+,36-,37?,39-,40+,41-,42+,43-,45?,47-,48+,49-/m1/s1
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4.5n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001564
PNG
(CHEMBL429949)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(42(54)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-27(6)59-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-44(56)50-26(5)23-58-43(50)55/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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5.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50409918
PNG
(CHEMBL275935)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)C2CCCC2)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C48H71Cl2N3O13/c1-12-36-48(9)40(52(44(57)66-48)20-19-31-17-18-33(49)34(50)22-31)28(5)37(54)25(2)23-47(8,60-11)41(65-43-38(55)35(21-27(4)62-43)51(10)32-15-13-14-16-32)29(6)39(30(7)42(56)63-36)64-46(59)53-26(3)24-61-45(53)58/h17-18,22,25-30,32,35-36,38-41,43,55H,12-16,19-21,23-24H2,1-11H3/t25-,26+,27-,28+,29+,30-,35+,36-,38-,39+,40-,41-,43?,47+,48-/m1/s1
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5.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001548
PNG
(CHEMBL412634)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](CC)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-14-33-24-59-44(56)51(33)45(57)62-38-29(8)40(63-42-37(53)34(22-27(6)60-42)49(12)25(3)4)46(10,58-13)23-26(5)36(52)28(7)39-47(11,35(15-2)61-41(54)30(38)9)64-43(55)50(39)21-20-31-16-18-32(48)19-17-31/h16-19,25-30,33-35,37-40,42,53H,14-15,20-24H2,1-13H3/t26-,27-,28+,29+,30-,33+,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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6.30n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001555
PNG
(CHEMBL267568)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CC(C)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(44(56)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-26(5)58-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-43(55)50-23-27(6)59-42(50)54/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26-,27?,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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7.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001559
PNG
(CHEMBL273536)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3C(=O)OCC3(C)C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-15-34-47(12)38(50(42(55)64-47)21-20-31-16-18-32(48)19-17-31)28(6)35(52)26(4)23-46(11,58-14)39(63-41-36(53)33(22-27(5)60-41)49(13)25(2)3)29(7)37(30(8)40(54)61-34)62-44(57)51-43(56)59-24-45(51,9)10/h16-19,25-30,33-34,36-39,41,53H,15,20-24H2,1-14H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,46+,47-/m1/s1
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8.90n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001569
PNG
(CHEMBL268489)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)C3CCOC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H71ClN2O12/c1-13-35-46(10)39(49(44(54)61-46)20-18-31-14-16-33(47)17-15-31)28(6)36(50)26(4)23-45(9,55-12)40(60-43-37(51)34(22-27(5)57-43)48(11)25(2)3)29(7)38(30(8)41(52)58-35)59-42(53)32-19-21-56-24-32/h14-17,25-30,32,34-35,37-40,43,51H,13,18-24H2,1-12H3/t26-,27-,28+,29+,30-,32?,34+,35-,37-,38+,39-,40-,43?,45+,46-/m1/s1
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14n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50409920
PNG
(CHEMBL273440)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](OC(=O)N2[C@@H](C)COC2=O)[C@H](C)[C@@H](OC2O[C@H](C)C[C@@H]([C@H]2O)N(C)C(C)C)[C@](C)(C[C@@H](C)C(=O)[C@H](C)[C@H]2N(CCc3ccc(Cl)c(Cl)c3)C(=O)O[C@]12C)OC
Show InChI InChI=1S/C46H69Cl2N3O13/c1-14-34-46(11)38(50(42(55)64-46)18-17-30-15-16-31(47)32(48)20-30)27(7)35(52)24(4)21-45(10,58-13)39(63-41-36(53)33(19-26(6)60-41)49(12)23(2)3)28(8)37(29(9)40(54)61-34)62-44(57)51-25(5)22-59-43(51)56/h15-16,20,23-29,33-34,36-39,41,53H,14,17-19,21-22H2,1-13H3/t24-,25+,26-,27+,28+,29-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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15n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001547
PNG
(CHEMBL430312)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CC(CC)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-14-33-24-51(43(55)60-33)44(56)62-38-29(8)40(63-42-37(53)34(22-27(6)59-42)49(12)25(3)4)46(10,58-13)23-26(5)36(52)28(7)39-47(11,35(15-2)61-41(54)30(38)9)64-45(57)50(39)21-20-31-16-18-32(48)19-17-31/h16-19,25-30,33-35,37-40,42,53H,14-15,20-24H2,1-13H3/t26-,27-,28+,29+,30-,33?,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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18n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001566
PNG
(CHEMBL275467)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(42(54)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-27(6)59-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-44(56)50-26(5)23-58-43(50)55/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26+,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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19n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001573
PNG
(CHEMBL273387)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C49H79ClN2O13/c1-16-36-49(12)41(52(46(57)65-49)22-21-33-17-19-34(50)20-18-33)29(6)38(53)27(4)24-48(11,59-15)43(64-45-39(54)35(23-28(5)60-45)51(13)26(2)3)30(7)40(31(8)44(56)62-36)63-37-25-47(10,58-14)42(55)32(9)61-37/h17-20,26-32,35-37,39-43,45,54-55H,16,21-25H2,1-15H3/t27-,28-,29+,30+,31-,32+,35+,36-,37?,39-,40+,41-,42+,43-,45?,47-,48+,49-/m1/s1
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22n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001555
PNG
(CHEMBL267568)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CC(C)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(44(56)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-26(5)58-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-43(55)50-23-27(6)59-42(50)54/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26-,27?,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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36n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001560
PNG
(CHEMBL273275)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C3CCCC3)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C48H72ClN3O13/c1-12-36-48(9)40(51(44(56)65-48)22-21-32-17-19-33(49)20-18-32)29(5)37(53)26(2)24-47(8,59-11)41(64-43-38(54)35(23-28(4)61-43)50(10)34-15-13-14-16-34)30(6)39(31(7)42(55)62-36)63-46(58)52-27(3)25-60-45(52)57/h17-20,26-31,34-36,38-41,43,54H,12-16,21-25H2,1-11H3/t26-,27+,28-,29+,30+,31-,35+,36-,38-,39+,40-,41-,43?,47+,48-/m1/s1
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38n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001564
PNG
(CHEMBL429949)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@H](C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H70ClN3O13/c1-14-34-46(11)38(49(42(54)63-46)20-19-31-15-17-32(47)18-16-31)28(7)35(51)25(4)22-45(10,57-13)39(62-41-36(52)33(21-27(6)59-41)48(12)24(2)3)29(8)37(30(9)40(53)60-34)61-44(56)50-26(5)23-58-43(50)55/h15-18,24-30,33-34,36-39,41,52H,14,19-23H2,1-13H3/t25-,26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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49n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001557
PNG
(CHEMBL428008)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)C3CCCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H73ClN2O11/c1-13-36-47(10)40(50(45(55)61-47)23-22-32-18-20-34(48)21-19-32)29(6)37(51)27(4)25-46(9,56-12)41(60-44-38(52)35(24-28(5)57-44)49(11)26(2)3)30(7)39(31(8)42(53)58-36)59-43(54)33-16-14-15-17-33/h18-21,26-31,33,35-36,38-41,44,52H,13-17,22-25H2,1-12H3/t27-,28-,29+,30+,31-,35+,36-,38-,39+,40-,41-,44?,46+,47-/m1/s1
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50n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001574
PNG
(CHEMBL12204)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H70ClN3O12/c1-13-34-45(10)38(49(43(54)61-45)19-18-31-14-16-32(46)17-15-31)28(6)35(50)26(4)23-44(9,55-12)39(60-41-36(51)33(22-27(5)57-41)47(11)25(2)3)29(7)37(30(8)40(52)58-34)59-42(53)48-20-21-56-24-48/h14-17,25-30,33-34,36-39,41,51H,13,18-24H2,1-12H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,44+,45-/m1/s1
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51n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined against rat Luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001548
PNG
(CHEMBL412634)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](CC)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-14-33-24-59-44(56)51(33)45(57)62-38-29(8)40(63-42-37(53)34(22-27(6)60-42)49(12)25(3)4)46(10,58-13)23-26(5)36(52)28(7)39-47(11,35(15-2)61-41(54)30(38)9)64-43(55)50(39)21-20-31-16-18-32(48)19-17-31/h16-19,25-30,33-35,37-40,42,53H,14-15,20-24H2,1-13H3/t26-,27-,28+,29+,30-,33+,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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66n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001559
PNG
(CHEMBL273536)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3C(=O)OCC3(C)C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-15-34-47(12)38(50(42(55)64-47)21-20-31-16-18-32(48)19-17-31)28(6)35(52)26(4)23-46(11,58-14)39(63-41-36(53)33(22-27(5)60-41)49(13)25(2)3)29(7)37(30(8)40(54)61-34)62-44(57)51-43(56)59-24-45(51,9)10/h16-19,25-30,33-34,36-39,41,53H,15,20-24H2,1-14H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,46+,47-/m1/s1
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79n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001563
PNG
(CHEMBL273535)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@@H](C)[C@@H](C)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-15-35-47(12)39(50(43(55)64-47)21-20-32-16-18-33(48)19-17-32)27(6)36(52)25(4)23-46(11,58-14)40(63-42-37(53)34(22-26(5)59-42)49(13)24(2)3)28(7)38(29(8)41(54)61-35)62-45(57)51-30(9)31(10)60-44(51)56/h16-19,24-31,34-35,37-40,42,53H,15,20-23H2,1-14H3/t25-,26-,27+,28+,29-,30+,31-,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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<100n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001558
PNG
(CHEMBL12666)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O11/c1-13-35-46(10)39(50(44(55)61-46)23-20-32-16-18-33(47)19-17-32)29(6)36(51)27(4)25-45(9,56-12)40(60-42-37(52)34(24-28(5)57-42)48(11)26(2)3)30(7)38(31(8)41(53)58-35)59-43(54)49-21-14-15-22-49/h16-19,26-31,34-35,37-40,42,52H,13-15,20-25H2,1-12H3/t27-,28-,29+,30+,31-,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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112n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001571
PNG
(CHEMBL273466)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H68ClN3O13/c1-13-33-45(10)37(48(43(55)62-45)19-18-30-14-16-31(46)17-15-30)27(6)34(50)25(4)23-44(9,56-12)38(61-40-35(51)32(22-26(5)58-40)47(11)24(2)3)28(7)36(29(8)39(52)59-33)60-42(54)49-20-21-57-41(49)53/h14-17,24-29,32-33,35-38,40,51H,13,18-23H2,1-12H3/t25-,26-,27+,28+,29-,32+,33-,35-,36+,37-,38-,40?,44+,45-/m1/s1
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115n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001567
PNG
(CHEMBL275521)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O12/c1-14-35-46(11)39(50(44(55)62-46)20-19-32-15-17-33(47)18-16-32)28(6)36(51)26(4)24-45(10,56-13)40(61-42-37(52)34(23-27(5)58-42)48(12)25(2)3)29(7)38(30(8)41(53)59-35)60-43(54)49-21-22-57-31(49)9/h15-18,25-31,34-35,37-40,42,52H,14,19-24H2,1-13H3/t26-,27-,28+,29+,30-,31?,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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120n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001570
PNG
(CHEMBL268491)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)CC(C)C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H73ClN2O11/c1-15-35-46(12)40(49(44(54)60-46)21-20-32-16-18-33(47)19-17-32)29(8)37(51)27(6)24-45(11,55-14)41(59-43-38(52)34(23-28(7)56-43)48(13)26(4)5)30(9)39(31(10)42(53)57-35)58-36(50)22-25(2)3/h16-19,25-31,34-35,38-41,43,52H,15,20-24H2,1-14H3/t27-,28-,29+,30+,31-,34+,35-,38-,39+,40-,41-,43?,45+,46-/m1/s1
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141n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001574
PNG
(CHEMBL12204)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H70ClN3O12/c1-13-34-45(10)38(49(43(54)61-45)19-18-31-14-16-32(46)17-15-31)28(6)35(50)26(4)23-44(9,55-12)39(60-41-36(51)33(22-27(5)57-41)47(11)25(2)3)29(7)37(30(8)40(52)58-34)59-42(53)48-20-21-56-24-48/h14-17,25-30,33-34,36-39,41,51H,13,18-24H2,1-12H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,44+,45-/m1/s1
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200n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined against human Luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001569
PNG
(CHEMBL268489)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)C3CCOC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H71ClN2O12/c1-13-35-46(10)39(49(44(54)61-46)20-18-31-14-16-33(47)17-15-31)28(6)36(50)26(4)23-45(9,55-12)40(60-43-37(51)34(22-27(5)57-43)48(11)25(2)3)29(7)38(30(8)41(52)58-35)59-42(53)32-19-21-56-24-32/h14-17,25-30,32,34-35,37-40,43,51H,13,18-24H2,1-12H3/t26-,27-,28+,29+,30-,32?,34+,35-,37-,38+,39-,40-,43?,45+,46-/m1/s1
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214n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001575
PNG
(CHEMBL12589)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCNC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H69ClN4O12/c1-13-33-45(10)37(49(43(56)62-45)20-18-30-14-16-31(46)17-15-30)27(6)34(51)25(4)23-44(9,57-12)38(61-40-35(52)32(22-26(5)58-40)48(11)24(2)3)28(7)36(29(8)39(53)59-33)60-42(55)50-21-19-47-41(50)54/h14-17,24-29,32-33,35-38,40,52H,13,18-23H2,1-12H3,(H,47,54)/t25-,26-,27+,28+,29-,32+,33-,35-,36+,37-,38-,40?,44+,45-/m1/s1
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219n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001549
PNG
(CHEMBL276217)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@H](CC(C)C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C49H76ClN3O13/c1-15-37-49(12)41(52(45(57)66-49)21-20-33-16-18-34(50)19-17-33)30(8)38(54)28(6)24-48(11,60-14)42(65-44-39(55)36(23-29(7)62-44)51(13)27(4)5)31(9)40(32(10)43(56)63-37)64-47(59)53-35(22-26(2)3)25-61-46(53)58/h16-19,26-32,35-37,39-42,44,55H,15,20-25H2,1-14H3/t28-,29-,30+,31+,32-,35-,36+,37-,39-,40+,41-,42-,44?,48+,49-/m1/s1
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275n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001565
PNG
(CHEMBL275251)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O12/c1-13-35-46(10)39(50(44(55)62-46)19-18-32-14-16-33(47)17-15-32)29(6)36(51)27(4)25-45(9,56-12)40(61-42-37(52)34(24-28(5)58-42)48(11)26(2)3)30(7)38(31(8)41(53)59-35)60-43(54)49-20-22-57-23-21-49/h14-17,26-31,34-35,37-40,42,52H,13,18-25H2,1-12H3/t27-,28-,29+,30+,31-,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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427n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001547
PNG
(CHEMBL430312)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CC(CC)OC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H72ClN3O13/c1-14-33-24-51(43(55)60-33)44(56)62-38-29(8)40(63-42-37(53)34(22-27(6)59-42)49(12)25(3)4)46(10,58-13)23-26(5)36(52)28(7)39-47(11,35(15-2)61-41(54)30(38)9)64-45(57)50(39)21-20-31-16-18-32(48)19-17-31/h16-19,25-30,33-35,37-40,42,53H,14-15,20-24H2,1-13H3/t26-,27-,28+,29+,30-,33?,34+,35-,37-,38+,39-,40-,42?,46+,47-/m1/s1
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562n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001557
PNG
(CHEMBL428008)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)C3CCCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C47H73ClN2O11/c1-13-36-47(10)40(50(45(55)61-47)23-22-32-18-20-34(48)21-19-32)29(6)37(51)27(4)25-46(9,56-12)41(60-44-38(52)35(24-28(5)57-44)49(11)26(2)3)30(7)39(31(8)42(53)58-36)59-43(54)33-16-14-15-17-33/h18-21,26-31,33,35-36,38-41,44,52H,13-17,22-25H2,1-12H3/t27-,28-,29+,30+,31-,35+,36-,38-,39+,40-,41-,44?,46+,47-/m1/s1
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631n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001549
PNG
(CHEMBL276217)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3[C@H](CC(C)C)COC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C49H76ClN3O13/c1-15-37-49(12)41(52(45(57)66-49)21-20-33-16-18-34(50)19-17-33)30(8)38(54)28(6)24-48(11,60-14)42(65-44-39(55)36(23-29(7)62-44)51(13)27(4)5)31(9)40(32(10)43(56)63-37)64-47(59)53-35(22-26(2)3)25-61-46(53)58/h16-19,26-32,35-37,39-42,44,55H,15,20-25H2,1-14H3/t28-,29-,30+,31+,32-,35-,36+,37-,39-,40+,41-,42-,44?,48+,49-/m1/s1
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692n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001567
PNG
(CHEMBL275521)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOC3C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O12/c1-14-35-46(11)39(50(44(55)62-46)20-19-32-15-17-33(47)18-16-32)28(6)36(51)26(4)24-45(10,56-13)40(61-42-37(52)34(23-27(5)58-42)48(12)25(2)3)29(7)38(30(8)41(53)59-35)60-43(54)49-21-22-57-31(49)9/h15-18,25-31,34-35,37-40,42,52H,14,19-24H2,1-13H3/t26-,27-,28+,29+,30-,31?,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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794n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001568
PNG
(CHEMBL416337)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCN(C)C3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H71ClN4O12/c1-14-34-46(10)38(50(44(57)63-46)20-19-31-15-17-32(47)18-16-31)28(6)35(52)26(4)24-45(9,58-13)39(62-41-36(53)33(23-27(5)59-41)49(12)25(2)3)29(7)37(30(8)40(54)60-34)61-43(56)51-22-21-48(11)42(51)55/h15-18,25-30,33-34,36-39,41,53H,14,19-24H2,1-13H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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1.23E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001558
PNG
(CHEMBL12666)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O11/c1-13-35-46(10)39(50(44(55)61-46)23-20-32-16-18-33(47)19-17-32)29(6)36(51)27(4)25-45(9,56-12)40(60-42-37(52)34(24-28(5)57-42)48(11)26(2)3)30(7)38(31(8)41(53)58-35)59-43(54)49-21-14-15-22-49/h16-19,26-31,34-35,37-40,42,52H,13-15,20-25H2,1-12H3/t27-,28-,29+,30+,31-,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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1.62E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001570
PNG
(CHEMBL268491)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)CC(C)C)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H73ClN2O11/c1-15-35-46(12)40(49(44(54)60-46)21-20-32-16-18-33(47)19-17-32)29(8)37(51)27(6)24-45(11,55-14)41(59-43-38(52)34(23-28(7)56-43)48(13)26(4)5)30(9)39(31(10)42(53)57-35)58-36(50)22-25(2)3/h16-19,25-31,34-35,38-41,43,52H,15,20-24H2,1-14H3/t27-,28-,29+,30+,31-,34+,35-,38-,39+,40-,41-,43?,45+,46-/m1/s1
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2.04E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001575
PNG
(CHEMBL12589)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCNC3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C45H69ClN4O12/c1-13-33-45(10)37(49(43(56)62-45)20-18-30-14-16-31(46)17-15-30)27(6)34(51)25(4)23-44(9,57-12)38(61-40-35(52)32(22-26(5)58-40)48(11)24(2)3)28(7)36(29(8)39(53)59-33)60-42(55)50-21-19-47-41(50)54/h14-17,24-29,32-33,35-38,40,52H,13,18-23H2,1-12H3,(H,47,54)/t25-,26-,27+,28+,29-,32+,33-,35-,36+,37-,38-,40?,44+,45-/m1/s1
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2.04E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)
BDBM50001550
PNG
(CHEMBL12265)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C41H65ClN2O10/c1-13-31-41(10)35(44(39(49)54-41)19-18-28-14-16-29(42)17-15-28)25(6)32(45)23(4)21-40(9,50-12)36(26(7)33(46)27(8)37(48)52-31)53-38-34(47)30(20-24(5)51-38)43(11)22(2)3/h14-17,22-27,30-31,33-36,38,46-47H,13,18-21H2,1-12H3/t23-,24-,25+,26+,27-,30+,31-,33+,34-,35-,36-,38?,40+,41-/m1/s1
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2.51E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to rat luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001568
PNG
(CHEMBL416337)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCN(C)C3=O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H71ClN4O12/c1-14-34-46(10)38(50(44(57)63-46)20-19-31-15-17-32(47)18-16-31)28(6)35(52)26(4)24-45(9,58-13)39(62-41-36(53)33(23-27(5)59-41)49(12)25(2)3)29(7)37(30(8)40(54)60-34)61-43(56)51-22-21-48(11)42(51)55/h15-18,25-30,33-34,36-39,41,53H,14,19-24H2,1-13H3/t26-,27-,28+,29+,30-,33+,34-,36-,37+,38-,39-,41?,45+,46-/m1/s1
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4.68E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001565
PNG
(CHEMBL275251)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](OC(=O)N3CCOCC3)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C46H72ClN3O12/c1-13-35-46(10)39(50(44(55)62-46)19-18-32-14-16-33(47)17-15-32)29(6)36(51)27(4)25-45(9,56-12)40(61-42-37(52)34(24-28(5)58-42)48(11)26(2)3)30(7)38(31(8)41(53)59-35)60-43(54)49-20-22-57-23-21-49/h14-17,26-31,34-35,37-40,42,52H,13,18-25H2,1-12H3/t27-,28-,29+,30+,31-,34+,35-,37-,38+,39-,40-,42?,45+,46-/m1/s1
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5.62E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1)


(Homo sapiens (Human))
BDBM50001550
PNG
(CHEMBL12265)
Show SMILES [H][C@@]12[C@@H](C)C(=O)[C@H](C)C[C@](C)(OC)[C@H](OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C(C)C)[C@@H](C)[C@H](O)[C@@H](C)C(=O)O[C@H](CC)[C@@]1(C)OC(=O)N2CCc1ccc(Cl)cc1
Show InChI InChI=1S/C41H65ClN2O10/c1-13-31-41(10)35(44(39(49)54-41)19-18-28-14-16-29(42)17-15-28)25(6)32(45)23(4)21-40(9,50-12)36(26(7)33(46)27(8)37(48)52-31)53-38-34(47)30(20-24(5)51-38)43(11)22(2)3/h14-17,22-27,30-31,33-36,38,46-47H,13,18-21H2,1-12H3/t23-,24-,25+,26+,27-,30+,31-,33+,34-,35-,36-,38?,40+,41-/m1/s1
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1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity to human luteinizing hormone-releasing hormone (LHRH) receptor cloned in CHO cells


J Med Chem 47: 1085-97 (2004)

Checked by Author
Article DOI: 10.1021/jm030418i
BindingDB Entry DOI: 10.7270/Q2ZG6TF5
More data for this
Ligand-Target Pair
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