new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 79 hits with Last Name = 'stanczak' and Initial = 'a'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349952
PNG
(CHEMBL1812284)
Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-33-24-11-5-4-10-23(24)30-16-14-29(15-17-30)12-6-7-13-31-19-28-25-20-8-2-3-9-22(20)27-18-21(25)26(31)32/h2-5,8-11,18-19H,6-7,12-17H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349968
PNG
(CHEMBL1812311)
Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3c4cc(C)ccc4ncc3c2=O)CC1
Show InChI InChI=1S/C27H31N5O2/c1-20-9-10-23-21(17-20)26-22(18-28-23)27(33)32(19-29-26)12-6-5-11-30-13-15-31(16-14-30)24-7-3-4-8-25(24)34-2/h3-4,7-10,17-19H,5-6,11-16H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
8n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349957
PNG
(CHEMBL1812292)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4ccc(C)cc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-18-7-8-19-21(15-18)26-16-20-24(19)27-17-30(25(20)31)14-11-28-9-12-29(13-10-28)22-5-3-4-6-23(22)32-2/h3-8,15-17H,9-14H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
14n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349950
PNG
(CHEMBL1812162)
Show SMILES Clc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26ClN5O/c26-21-8-2-4-10-23(21)30-15-13-29(14-16-30)11-5-6-12-31-18-28-24-19-7-1-3-9-22(19)27-17-20(24)25(31)32/h1-4,7-10,17-18H,5-6,11-16H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
17n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349962
PNG
(CHEMBL1812300)
Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3c4ccc(C)cc4ncc3c2=O)CC1
Show InChI InChI=1S/C27H31N5O2/c1-20-9-10-21-23(17-20)28-18-22-26(21)29-19-32(27(22)33)12-6-5-11-30-13-15-31(16-14-30)24-7-3-4-8-25(24)34-2/h3-4,7-10,17-19H,5-6,11-16H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
20n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349943
PNG
(CHEMBL1812277)
Show SMILES COc1ccccc1N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-32-23-10-5-4-9-22(23)29-15-13-28(14-16-29)11-6-12-30-18-27-24-19-7-2-3-8-21(19)26-17-20(24)25(30)31/h2-5,7-10,17-18H,6,11-16H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
20n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349966
PNG
(CHEMBL1812308)
Show SMILES COc1ccccc1N1CCN(CCCn2cnc3c4cc(C)ccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-19-8-9-22-20(16-19)25-21(17-27-22)26(32)31(18-28-25)11-5-10-29-12-14-30(15-13-29)23-6-3-4-7-24(23)33-2/h3-4,6-9,16-18H,5,10-15H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
26n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349949
PNG
(CHEMBL1812165)
Show SMILES O=c1n(CCCCN2CCN(CC2)c2ccccc2)cnc2c3ccccc3ncc12
Show InChI InChI=1S/C25H27N5O/c31-25-22-18-26-23-11-5-4-10-21(23)24(22)27-19-30(25)13-7-6-12-28-14-16-29(17-15-28)20-8-2-1-3-9-20/h1-5,8-11,18-19H,6-7,12-17H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
28n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349953
PNG
(CHEMBL1812285)
Show SMILES COc1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-33-21-8-6-7-20(17-21)30-15-13-29(14-16-30)11-4-5-12-31-19-28-25-22-9-2-3-10-24(22)27-18-23(25)26(31)32/h2-3,6-10,17-19H,4-5,11-16H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
31n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349960
PNG
(CHEMBL1812297)
Show SMILES COc1ccccc1N1CCN(CCCn2cnc3c4ccc(C)cc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-19-8-9-20-22(16-19)27-17-21-25(20)28-18-31(26(21)32)11-5-10-29-12-14-30(15-13-29)23-6-3-4-7-24(23)33-2/h3-4,6-9,16-18H,5,10-15H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
31n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349951
PNG
(CHEMBL1812282)
Show SMILES Clc1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26ClN5O/c26-19-6-5-7-20(16-19)30-14-12-29(13-15-30)10-3-4-11-31-18-28-24-21-8-1-2-9-23(21)27-17-22(24)25(31)32/h1-2,5-9,16-18H,3-4,10-15H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
34n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349937
PNG
(CHEMBL1812168)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H25N5O2/c1-31-22-9-5-4-8-21(22)28-13-10-27(11-14-28)12-15-29-17-26-23-18-6-2-3-7-20(18)25-16-19(23)24(29)30/h2-9,16-17H,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
42n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349940
PNG
(CHEMBL1812273)
Show SMILES O=c1n(CCCN2CCN(CC2)c2ccccc2)cnc2c3ccccc3ncc12
Show InChI InChI=1S/C24H25N5O/c30-24-21-17-25-22-10-5-4-9-20(22)23(21)26-18-29(24)12-6-11-27-13-15-28(16-14-27)19-7-2-1-3-8-19/h1-5,7-10,17-18H,6,11-16H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
47n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349948
PNG
(CHEMBL1812164)
Show SMILES O=c1n(CCCN2CCN(CC2)c2ccc(cc2)-c2ncccn2)cnc2c3ccccc3ncc12
Show InChI InChI=1S/C28H27N7O/c36-28-24-19-31-25-6-2-1-5-23(25)26(24)32-20-35(28)14-4-13-33-15-17-34(18-16-33)22-9-7-21(8-10-22)27-29-11-3-12-30-27/h1-3,5-12,19-20H,4,13-18H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
48n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349955
PNG
(CHEMBL1812289)
Show SMILES Cc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O/c1-20-8-2-5-11-24(20)30-16-14-29(15-17-30)12-6-7-13-31-19-28-25-21-9-3-4-10-23(21)27-18-22(25)26(31)32/h2-5,8-11,18-19H,6-7,12-17H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
52n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349945
PNG
(CHEMBL1812279)
Show SMILES Fc1ccccc1N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H24FN5O/c25-20-7-2-4-9-22(20)29-14-12-28(13-15-29)10-5-11-30-17-27-23-18-6-1-3-8-21(18)26-16-19(23)24(30)31/h1-4,6-9,16-17H,5,10-15H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
55n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349936
PNG
(CHEMBL1812166)
Show SMILES Clc1cccc(c1)N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C23H22ClN5O/c24-17-4-3-5-18(14-17)28-11-8-27(9-12-28)10-13-29-16-26-22-19-6-1-2-7-21(19)25-15-20(22)23(29)30/h1-7,14-16H,8-13H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
55n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349954
PNG
(CHEMBL1812287)
Show SMILES Fc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26FN5O/c26-21-8-2-4-10-23(21)30-15-13-29(14-16-30)11-5-6-12-31-18-28-24-19-7-1-3-9-22(19)27-17-20(24)25(31)32/h1-4,7-10,17-18H,5-6,11-16H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
63n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349967
PNG
(CHEMBL1812310)
Show SMILES Cc1ccc2ncc3c(ncn(CCCCN4CCN(CC4)c4cccc(Cl)c4)c3=O)c2c1
Show InChI InChI=1S/C26H28ClN5O/c1-19-7-8-24-22(15-19)25-23(17-28-24)26(33)32(18-29-25)10-3-2-9-30-11-13-31(14-12-30)21-6-4-5-20(27)16-21/h4-8,15-18H,2-3,9-14H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
67n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349935
PNG
(CHEMBL1812173)
Show SMILES Clc1ccccc1N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C23H22ClN5O/c24-19-6-2-4-8-21(19)28-12-9-27(10-13-28)11-14-29-16-26-22-17-5-1-3-7-20(17)25-15-18(22)23(29)30/h1-8,15-16H,9-14H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
78n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349942
PNG
(CHEMBL1812275)
Show SMILES Clc1cccc(c1)N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H24ClN5O/c25-18-5-3-6-19(15-18)29-13-11-28(12-14-29)9-4-10-30-17-27-23-20-7-1-2-8-22(20)26-16-21(23)24(30)31/h1-3,5-8,15-17H,4,9-14H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
80n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349964
PNG
(CHEMBL1812303)
Show SMILES COc1ccccc1N1CCN(CCn2cnc3c4cc(C)ccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-18-7-8-21-19(15-18)24-20(16-26-21)25(31)30(17-27-24)14-11-28-9-12-29(13-10-28)22-5-3-4-6-23(22)32-2/h3-8,15-17H,9-14H2,1-2H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
82n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349963
PNG
(CHEMBL1812301)
Show SMILES Cc1ccc2c(c1)ncc1c2ncn(CCCCN2CCN(CC2)c2ccccc2F)c1=O
Show InChI InChI=1S/C26H28FN5O/c1-19-8-9-20-23(16-19)28-17-21-25(20)29-18-32(26(21)33)11-5-4-10-30-12-14-31(15-13-30)24-7-3-2-6-22(24)27/h2-3,6-9,16-18H,4-5,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
83n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349941
PNG
(CHEMBL1812274)
Show SMILES Clc1ccccc1N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H24ClN5O/c25-20-7-2-4-9-22(20)29-14-12-28(13-15-29)10-5-11-30-17-27-23-18-6-1-3-8-21(18)26-16-19(23)24(30)31/h1-4,6-9,16-17H,5,10-15H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
93n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349969
PNG
(CHEMBL1812312)
Show SMILES Cc1ccc2ncc3c(ncn(CCCCN4CCN(CC4)c4ccccc4F)c3=O)c2c1
Show InChI InChI=1S/C26H28FN5O/c1-19-8-9-23-20(16-19)25-21(17-28-23)26(33)32(18-29-25)11-5-4-10-30-12-14-31(15-13-30)24-7-3-2-6-22(24)27/h2-3,6-9,16-18H,4-5,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
97n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349944
PNG
(CHEMBL1812278)
Show SMILES COc1cccc(c1)N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H27N5O2/c1-32-20-7-4-6-19(16-20)29-14-12-28(13-15-29)10-5-11-30-18-27-24-21-8-2-3-9-23(21)26-17-22(24)25(30)31/h2-4,6-9,16-18H,5,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
120n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349959
PNG
(CHEMBL1812295)
Show SMILES Cc1ccc2c(c1)ncc1c2ncn(CCCN2CCN(CC2)c2ccccc2)c1=O
Show InChI InChI=1S/C25H27N5O/c1-19-8-9-21-23(16-19)26-17-22-24(21)27-18-30(25(22)31)11-5-10-28-12-14-29(15-13-28)20-6-3-2-4-7-20/h2-4,6-9,16-18H,5,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
125n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349956
PNG
(CHEMBL1812290)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H26F3N5O/c27-26(28,29)19-6-5-7-20(16-19)33-14-12-32(13-15-33)10-3-4-11-34-18-31-24-21-8-1-2-9-23(21)30-17-22(24)25(34)35/h1-2,5-9,16-18H,3-4,10-15H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
127n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349965
PNG
(CHEMBL1812306)
Show SMILES Cc1ccc2ncc3c(ncn(CCCN4CCN(CC4)c4ccccc4)c3=O)c2c1
Show InChI InChI=1S/C25H27N5O/c1-19-8-9-23-21(16-19)24-22(17-26-23)25(31)30(18-27-24)11-5-10-28-12-14-29(15-13-28)20-6-3-2-4-7-20/h2-4,6-9,16-18H,5,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
128n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349946
PNG
(CHEMBL1812280)
Show SMILES Fc1ccc(cc1)N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H24FN5O/c25-18-6-8-19(9-7-18)29-14-12-28(13-15-29)10-3-11-30-17-27-23-20-4-1-2-5-22(20)26-16-21(23)24(30)31/h1-2,4-9,16-17H,3,10-15H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
129n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349950
PNG
(CHEMBL1812162)
Show SMILES Clc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26ClN5O/c26-21-8-2-4-10-23(21)30-15-13-29(14-16-30)11-5-6-12-31-18-28-24-19-7-1-3-9-22(19)27-17-20(24)25(31)32/h1-4,7-10,17-18H,5-6,11-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
153n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349939
PNG
(CHEMBL1812176)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H22F3N5O/c25-24(26,27)17-4-3-5-18(14-17)31-11-8-30(9-12-31)10-13-32-16-29-22-19-6-1-2-7-21(19)28-15-20(22)23(32)33/h1-7,14-16H,8-13H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
160n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349961
PNG
(CHEMBL1812299)
Show SMILES Cc1ccc2c(c1)ncc1c2ncn(CCCCN2CCN(CC2)c2cccc(Cl)c2)c1=O
Show InChI InChI=1S/C26H28ClN5O/c1-19-7-8-22-24(15-19)28-17-23-25(22)29-18-32(26(23)33)10-3-2-9-30-11-13-31(14-12-30)21-6-4-5-20(27)16-21/h4-8,15-18H,2-3,9-14H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
172n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349951
PNG
(CHEMBL1812282)
Show SMILES Clc1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26ClN5O/c26-19-6-5-7-20(16-19)30-14-12-29(13-15-30)10-3-4-11-31-18-28-24-21-8-1-2-9-23(21)27-17-22(24)25(31)32/h1-2,5-9,16-18H,3-4,10-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
184n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349958
PNG
(CHEMBL1812294)
Show SMILES Cc1ccc2c(c1)ncc1c2ncn(CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)c1=O
Show InChI InChI=1S/C25H24F3N5O/c1-17-5-6-20-22(13-17)29-15-21-23(20)30-16-33(24(21)34)12-9-31-7-10-32(11-8-31)19-4-2-3-18(14-19)25(26,27)28/h2-6,13-16H,7-12H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
241n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349947
PNG
(CHEMBL1812163)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H24F3N5O/c26-25(27,28)18-5-3-6-19(15-18)32-13-11-31(12-14-32)9-4-10-33-17-30-23-20-7-1-2-8-22(20)29-16-21(23)24(33)34/h1-3,5-8,15-17H,4,9-14H2
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
243n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349952
PNG
(CHEMBL1812284)
Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-33-24-11-5-4-10-23(24)30-16-14-29(15-17-30)12-6-7-13-31-19-28-25-20-8-2-3-9-22(20)27-18-21(25)26(31)32/h2-5,8-11,18-19H,6-7,12-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
276n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349955
PNG
(CHEMBL1812289)
Show SMILES Cc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O/c1-20-8-2-5-11-24(20)30-16-14-29(15-17-30)12-6-7-13-31-19-28-25-21-9-3-4-10-23(21)27-18-22(25)26(31)32/h2-5,8-11,18-19H,6-7,12-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
296n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349970
PNG
(CHEMBL1812283)
Show SMILES Clc1ccc(cc1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26ClN5O/c26-19-7-9-20(10-8-19)30-15-13-29(14-16-30)11-3-4-12-31-18-28-24-21-5-1-2-6-23(21)27-17-22(24)25(31)32/h1-2,5-10,17-18H,3-4,11-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
328n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349972
PNG
(CHEMBL1812288)
Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26FN5O/c26-19-7-9-20(10-8-19)30-15-13-29(14-16-30)11-3-4-12-31-18-28-24-21-5-1-2-6-23(21)27-17-22(24)25(31)32/h1-2,5-10,17-18H,3-4,11-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
404n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349956
PNG
(CHEMBL1812290)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H26F3N5O/c27-26(28,29)19-6-5-7-20(16-19)33-14-12-32(13-15-33)10-3-4-11-34-18-31-24-21-8-1-2-9-23(21)30-17-22(24)25(34)35/h1-2,5-9,16-18H,3-4,10-15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
418n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349953
PNG
(CHEMBL1812285)
Show SMILES COc1cccc(c1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-33-21-8-6-7-20(17-21)30-15-13-29(14-16-30)11-4-5-12-31-19-28-25-22-9-2-3-10-24(22)27-18-23(25)26(31)32/h2-3,6-10,17-19H,4-5,11-16H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
484n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50349938
PNG
(CHEMBL1812175)
Show SMILES Cc1ccccc1N1CCN(CCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C24H25N5O/c1-18-6-2-5-9-22(18)28-13-10-27(11-14-28)12-15-29-17-26-23-19-7-3-4-8-21(19)25-16-20(23)24(29)30/h2-9,16-17H,10-15H2,1H3
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
514n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membrane by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349949
PNG
(CHEMBL1812165)
Show SMILES O=c1n(CCCCN2CCN(CC2)c2ccccc2)cnc2c3ccccc3ncc12
Show InChI InChI=1S/C25H27N5O/c31-25-22-18-26-23-11-5-4-10-21(23)24(22)27-19-30(25)13-7-6-12-28-14-16-29(17-15-28)20-8-2-1-3-9-20/h1-5,8-11,18-19H,6-7,12-17H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
612n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349954
PNG
(CHEMBL1812287)
Show SMILES Fc1ccccc1N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C25H26FN5O/c26-21-8-2-4-10-23(21)30-15-13-29(14-16-30)11-5-6-12-31-18-28-24-19-7-1-3-9-22(19)27-17-20(24)25(31)32/h1-4,7-10,17-18H,5-6,11-16H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
739n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349973
PNG
(CHEMBL1812291)
Show SMILES O=c1n(CCCCN2CCN(CC2)c2ccc(cc2)-c2ncccn2)cnc2c3ccccc3ncc12
Show InChI InChI=1S/C29H29N7O/c37-29-25-20-32-26-7-2-1-6-24(26)27(25)33-21-36(29)15-4-3-14-34-16-18-35(19-17-34)23-10-8-22(9-11-23)28-30-12-5-13-31-28/h1-2,5-13,20-21H,3-4,14-19H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
5.80E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7)


(Homo sapiens (Human))
BDBM50349971
PNG
(CHEMBL1812286)
Show SMILES COc1ccc(cc1)N1CCN(CCCCn2cnc3c4ccccc4ncc3c2=O)CC1
Show InChI InChI=1S/C26H29N5O2/c1-33-21-10-8-20(9-11-21)30-16-14-29(15-17-30)12-4-5-13-31-19-28-25-22-6-2-3-7-24(22)27-18-23(25)26(31)32/h2-3,6-11,18-19H,4-5,12-17H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells by radioligand binding assay


Eur J Med Chem 46: 3348-61 (2011)


Article DOI: 10.1016/j.ejmech.2011.04.060
BindingDB Entry DOI: 10.7270/Q21836VH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM342461
PNG
(US9776988, Example 21)
Show SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3ccc(cc3[nH]2)N2CCN(CC2)C(=O)N2CCOCC2)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.950n/an/an/an/an/an/a



Celon Pharma S.A.

US Patent




US Patent US9776988 (2017)


BindingDB Entry DOI: 10.7270/Q27946S6
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM342487
PNG
(US9776988, Example 3)
Show SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3ccc(cc3[nH]2)C(=O)NC2CCOCC2)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.07n/an/an/an/an/an/a



Celon Pharma S.A.

US Patent




US Patent US9776988 (2017)


BindingDB Entry DOI: 10.7270/Q27946S6
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM342463
PNG
(US9776988, Example 27)
Show SMILES COc1cc(CCc2cc(n[nH]2)-c2nc3ccc(cc3[nH]2)-c2ccn(CCN3CCOCC3)n2)cc(OC)c1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.26n/an/an/an/an/an/a



Celon Pharma S.A.

US Patent




US Patent US9776988 (2017)


BindingDB Entry DOI: 10.7270/Q27946S6
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 79 total )  |  Next  |  Last  >>
Jump to: