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Compile Data Set for Download or QSAR

Found 199 hits with Last Name = 'tasso' and Initial = 'b'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50143282
PNG
((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12
Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1
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0.340n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Homo sapiens (Human))
BDBM50428369
PNG
((+)-Anatoxin-A | CHEMBL2332144)
Show SMILES CC(=O)C1=CCC[C@@H]2CC[C@H]1N2 |r,t:3|
Show InChI InChI=1S/C10H15NO/c1-7(12)9-4-2-3-8-5-6-10(9)11-8/h4,8,10-11H,2-3,5-6H2,1H3/t8-,10-/m1/s1
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0.340n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]nicotine from alpha4beta2 nAChR (unknown origin)


J Nat Prod 76: 727-31 (2013)


Article DOI: 10.1021/np3007028
BindingDB Entry DOI: 10.7270/Q2F1912Q
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50143282
PNG
((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12
Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1
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0.480n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279279
PNG
(1-Phenyl-3-(cytisin-12-yl)-1-propanone | CHEMBL502...)
Show SMILES O=C(CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C20H22N2O2/c23-19(16-5-2-1-3-6-16)9-10-21-12-15-11-17(14-21)18-7-4-8-20(24)22(18)13-15/h1-8,15,17H,9-14H2
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2.60n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50240956
PNG
((1R,5S)-3-(3-Oxo-butyl)-1,2,3,4,5,6-hexahydro-1,5-...)
Show SMILES CC(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C15H20N2O2/c1-11(18)5-6-16-8-12-7-13(10-16)14-3-2-4-15(19)17(14)9-12/h2-4,12-13H,5-10H2,1H3
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3.20n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Cholinesterases


(Homo sapiens (Human))
BDBM50219206
PNG
(Anthracen-9-yl (10H-phenothiazine-10yl) methanone,...)
Show SMILES O=C(N1c2ccccc2Sc2ccccc12)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C27H17NOS/c29-27(26-20-11-3-1-9-18(20)17-19-10-2-4-12-21(19)26)28-22-13-5-7-15-24(22)30-25-16-8-6-14-23(25)28/h1-17H
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3.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Inhibition of human erythrocytes BChE


Eur J Med Chem 46: 2170-84 (2011)


Article DOI: 10.1016/j.ejmech.2011.02.071
BindingDB Entry DOI: 10.7270/Q2BK1CPG
More data for this
Ligand-Target Pair
Cholinesterases


(Homo sapiens (Human))
BDBM50219206
PNG
(Anthracen-9-yl (10H-phenothiazine-10yl) methanone,...)
Show SMILES O=C(N1c2ccccc2Sc2ccccc12)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C27H17NOS/c29-27(26-20-11-3-1-9-18(20)17-19-10-2-4-12-21(19)26)28-22-13-5-7-15-24(22)30-25-16-8-6-14-23(25)28/h1-17H
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3.5n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Inhibition of human plasma BChE


Eur J Med Chem 46: 2170-84 (2011)


Article DOI: 10.1016/j.ejmech.2011.02.071
BindingDB Entry DOI: 10.7270/Q2BK1CPG
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279280
PNG
(1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...)
Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2
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5.30n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279279
PNG
(1-Phenyl-3-(cytisin-12-yl)-1-propanone | CHEMBL502...)
Show SMILES O=C(CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C20H22N2O2/c23-19(16-5-2-1-3-6-16)9-10-21-12-15-11-17(14-21)18-7-4-8-20(24)22(18)13-15/h1-8,15,17H,9-14H2
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7.20n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279210
PNG
(CHEMBL525735 | N-[2-(Pyridin-4-yl)ethyl]cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCc4ccncc4)C3)Cn12 |r|
Show InChI InChI=1S/C18H21N3O/c22-18-3-1-2-17-16-10-15(12-21(17)18)11-20(13-16)9-6-14-4-7-19-8-5-14/h1-5,7-8,15-16H,6,9-13H2
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7.20n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50240956
PNG
((1R,5S)-3-(3-Oxo-butyl)-1,2,3,4,5,6-hexahydro-1,5-...)
Show SMILES CC(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C15H20N2O2/c1-11(18)5-6-16-8-12-7-13(10-16)14-3-2-4-15(19)17(14)9-12/h2-4,12-13H,5-10H2,1H3
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8.70n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279280
PNG
(1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...)
Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2
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13n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279277
PNG
(1-Phenyl-2-(cytisin-12-yl)-1-ethanone | CHEMBL5020...)
Show SMILES O=C(CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C19H20N2O2/c22-18(15-5-2-1-3-6-15)13-20-10-14-9-16(12-20)17-7-4-8-19(23)21(17)11-14/h1-8,14,16H,9-13H2
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17n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279206
PNG
((1R,5S)-3-Phenethyl-1,2,3,4,5,6-hexahydro-1,5-meth...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C19H22N2O/c22-19-8-4-7-18-17-11-16(13-21(18)19)12-20(14-17)10-9-15-5-2-1-3-6-15/h1-8,16-17H,9-14H2
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28n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279333
PNG
(3-(Cytisin-12-yl)propionamide | CHEMBL483804)
Show SMILES NC(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C14H19N3O2/c15-13(18)4-5-16-7-10-6-11(9-16)12-2-1-3-14(19)17(12)8-10/h1-3,10-11H,4-9H2,(H2,15,18)
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35n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279242
PNG
((1R,5S)-3-(3-Phenyl-propyl)-1,2,3,4,5,6-hexahydro-...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C20H24N2O/c23-20-10-4-9-19-18-12-17(14-22(19)20)13-21(15-18)11-5-8-16-6-2-1-3-7-16/h1-4,6-7,9-10,17-18H,5,8,11-15H2
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42n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279367
PNG
((1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Show SMILES CCCCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C16H24N2O/c1-2-3-4-8-17-10-13-9-14(12-17)15-6-5-7-16(19)18(15)11-13/h5-7,13-14H,2-4,8-12H2,1H3
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43.5n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279242
PNG
((1R,5S)-3-(3-Phenyl-propyl)-1,2,3,4,5,6-hexahydro-...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C20H24N2O/c23-20-10-4-9-19-18-12-17(14-22(19)20)13-21(15-18)11-5-8-16-6-2-1-3-7-16/h1-4,6-7,9-10,17-18H,5,8,11-15H2
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63n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279206
PNG
((1R,5S)-3-Phenethyl-1,2,3,4,5,6-hexahydro-1,5-meth...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C19H22N2O/c22-19-8-4-7-18-17-11-16(13-21(18)19)12-20(14-17)10-9-15-5-2-1-3-6-15/h1-8,16-17H,9-14H2
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78n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))
BDBM50428369
PNG
((+)-Anatoxin-A | CHEMBL2332144)
Show SMILES CC(=O)C1=CCC[C@@H]2CC[C@H]1N2 |r,t:3|
Show InChI InChI=1S/C10H15NO/c1-7(12)9-4-2-3-8-5-6-10(9)11-8/h4,8,10-11H,2-3,5-6H2,1H3/t8-,10-/m1/s1
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91n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR (unknown origin)


J Nat Prod 76: 727-31 (2013)


Article DOI: 10.1021/np3007028
BindingDB Entry DOI: 10.7270/Q2F1912Q
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Homo sapiens (Human))
BDBM50428368
PNG
(CHEMBL2332145)
Show SMILES CC(=O)C1=CC[C@@H]2CC[C@H]1N2 |r,t:3|
Show InChI InChI=1S/C9H13NO/c1-6(11)8-4-2-7-3-5-9(8)10-7/h4,7,9-10H,2-3,5H2,1H3/t7-,9-/m1/s1
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94n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin)


J Nat Prod 76: 727-31 (2013)


Article DOI: 10.1021/np3007028
BindingDB Entry DOI: 10.7270/Q2F1912Q
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279278
PNG
((1R,5S)-3-[2-(4-Fluoro-phenyl)-2-oxo-ethyl]-1,2,3,...)
Show SMILES Fc1ccc(cc1)C(=O)CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C19H19FN2O2/c20-16-6-4-14(5-7-16)18(23)12-21-9-13-8-15(11-21)17-2-1-3-19(24)22(17)10-13/h1-7,13,15H,8-12H2
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172n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279176
PNG
((1R,5S)-3-(4-Fluoro-benzyl)-1,2,3,4,5,6-hexahydro-...)
Show SMILES Fc1ccc(CN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)cc1 |r|
Show InChI InChI=1S/C18H19FN2O/c19-16-6-4-13(5-7-16)9-20-10-14-8-15(12-20)17-2-1-3-18(22)21(17)11-14/h1-7,14-15H,8-12H2
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183n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM82070
PNG
(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Show SMILES CN1CCC[C@H]1c1cccnc1 |r|
Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
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230n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampus


J Nat Prod 76: 727-31 (2013)


Article DOI: 10.1021/np3007028
BindingDB Entry DOI: 10.7270/Q2F1912Q
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50143282
PNG
((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12
Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1
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230n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampus


J Nat Prod 76: 727-31 (2013)


Article DOI: 10.1021/np3007028
BindingDB Entry DOI: 10.7270/Q2F1912Q
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279176
PNG
((1R,5S)-3-(4-Fluoro-benzyl)-1,2,3,4,5,6-hexahydro-...)
Show SMILES Fc1ccc(CN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)cc1 |r|
Show InChI InChI=1S/C18H19FN2O/c19-16-6-4-13(5-7-16)9-20-10-14-8-15(12-20)17-2-1-3-18(22)21(17)11-14/h1-7,14-15H,8-12H2
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330n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50143282
PNG
((-)-cytisine | (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-m...)
Show SMILES O=c1cccc2[C@H]3CNC[C@H](C3)Cn12
Show InChI InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8?,9-/m1/s1
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331n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279367
PNG
((1R,5S)-3-Pentyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Show SMILES CCCCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C16H24N2O/c1-2-3-4-8-17-10-13-9-14(12-17)15-6-5-7-16(19)18(15)11-13/h5-7,13-14H,2-4,8-12H2,1H3
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332n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279278
PNG
((1R,5S)-3-[2-(4-Fluoro-phenyl)-2-oxo-ethyl]-1,2,3,...)
Show SMILES Fc1ccc(cc1)C(=O)CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C19H19FN2O2/c20-16-6-4-14(5-7-16)18(23)12-21-9-13-8-15(11-21)17-2-1-3-19(24)22(17)10-13/h1-7,13,15H,8-12H2
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409n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279280
PNG
(1-(4-Fluorophenyl)-3-(cytisin-12-yl)-1-propanone |...)
Show SMILES Fc1ccc(cc1)C(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C20H21FN2O2/c21-17-6-4-15(5-7-17)19(24)8-9-22-11-14-10-16(13-22)18-2-1-3-20(25)23(18)12-14/h1-7,14,16H,8-13H2
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433n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279279
PNG
(1-Phenyl-3-(cytisin-12-yl)-1-propanone | CHEMBL502...)
Show SMILES O=C(CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C20H22N2O2/c23-19(16-5-2-1-3-6-16)9-10-21-12-15-11-17(14-21)18-7-4-8-20(24)22(18)13-15/h1-8,15,17H,9-14H2
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550n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279334
PNG
(CHEMBL520478 | N-[2-(Methylsulfonyl)ethyl]cytisine)
Show SMILES NS(=O)(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C13H19N3O3S/c14-20(18,19)5-4-15-7-10-6-11(9-15)12-2-1-3-13(17)16(12)8-10/h1-3,10-11H,4-9H2,(H2,14,18,19)
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564n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279243
PNG
(CHEMBL526340 | N-[3-(4-Fluorophenyl)propyl]cytisin...)
Show SMILES Fc1ccc(CCCN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)cc1 |r|
Show InChI InChI=1S/C20H23FN2O/c21-18-8-6-15(7-9-18)3-2-10-22-12-16-11-17(14-22)19-4-1-5-20(24)23(19)13-16/h1,4-9,16-17H,2-3,10-14H2
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611n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279331
PNG
((1R,5S)-3-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C21H23FN2O2/c22-18-8-6-16(7-9-18)20(25)4-2-10-23-12-15-11-17(14-23)19-3-1-5-21(26)24(19)13-15/h1,3,5-9,15,17H,2,4,10-14H2
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670n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279178
PNG
(CHEMBL522410 | N-[(Pyridin-4-yl)methyl]cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccncc4)C3)Cn12 |r|
Show InChI InChI=1S/C17H19N3O/c21-17-3-1-2-16-15-8-14(11-20(16)17)10-19(12-15)9-13-4-6-18-7-5-13/h1-7,14-15H,8-12H2
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675n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279208
PNG
(CHEMBL502374 | N-[2-(4-Methylphenyl)ethyl]cytisine)
Show SMILES Cc1ccc(CCN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)cc1 |r|
Show InChI InChI=1S/C20H24N2O/c1-15-5-7-16(8-6-15)9-10-21-12-17-11-18(14-21)19-3-2-4-20(23)22(19)13-17/h2-8,17-18H,9-14H2,1H3
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727n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279245
PNG
(CHEMBL499635 | N-[3-(Pyridin-3-yl)propyl]cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCCc4cccnc4)C3)Cn12 |r|
Show InChI InChI=1S/C19H23N3O/c23-19-7-1-6-18-17-10-16(13-22(18)19)12-21(14-17)9-3-5-15-4-2-8-20-11-15/h1-2,4,6-8,11,16-17H,3,5,9-10,12-14H2
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744n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279366
PNG
(1-Methyl-4-(cytisin-12-yl)-1-butanone | CHEMBL4841...)
Show SMILES CC(=O)CCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C16H22N2O2/c1-12(19)4-3-7-17-9-13-8-14(11-17)15-5-2-6-16(20)18(15)10-13/h2,5-6,13-14H,3-4,7-11H2,1H3
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757n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279330
PNG
(1-Phenyl-4-(cytisin-12-yl)-1-butanone | CHEMBL5211...)
Show SMILES O=C(CCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C21H24N2O2/c24-20(17-6-2-1-3-7-17)9-5-11-22-13-16-12-18(15-22)19-8-4-10-21(25)23(19)14-16/h1-4,6-8,10,16,18H,5,9,11-15H2
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816n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279175
PNG
((1R,5S)-3-Benzyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C18H20N2O/c21-18-8-4-7-17-16-9-15(12-20(17)18)11-19(13-16)10-14-5-2-1-3-6-14/h1-8,15-16H,9-13H2
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850n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279209
PNG
(CHEMBL498277 | N-[2-(Pyridin-2-yl)ethyl]cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCc4ccccn4)C3)Cn12 |r|
Show InChI InChI=1S/C18H21N3O/c22-18-6-3-5-17-15-10-14(12-21(17)18)11-20(13-15)9-7-16-4-1-2-8-19-16/h1-6,8,14-15H,7,9-13H2
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941n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279331
PNG
((1R,5S)-3-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,2,3,...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C21H23FN2O2/c22-18-8-6-16(7-9-18)20(25)4-2-10-23-12-15-11-17(14-23)19-3-1-5-21(26)24(19)13-15/h1,3,5-9,15,17H,2,4,10-14H2
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965n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279175
PNG
((1R,5S)-3-Benzyl-1,2,3,4,5,6-hexahydro-1,5-methano...)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(Cc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C18H20N2O/c21-18-8-4-7-17-16-9-15(12-20(17)18)11-19(13-16)10-14-5-2-1-3-6-14/h1-8,15-16H,9-13H2
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1.00E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50240956
PNG
((1R,5S)-3-(3-Oxo-butyl)-1,2,3,4,5,6-hexahydro-1,5-...)
Show SMILES CC(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C15H20N2O2/c1-11(18)5-6-16-8-12-7-13(10-16)14-3-2-4-15(19)17(14)9-12/h2-4,12-13H,5-10H2,1H3
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1.24E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279207
PNG
(CHEMBL525734 | N-[2-(4-Fluorophenyl)ethyl]cytisine)
Show SMILES Fc1ccc(CCN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)cc1 |r|
Show InChI InChI=1S/C19H21FN2O/c20-17-6-4-14(5-7-17)8-9-21-11-15-10-16(13-21)18-2-1-3-19(23)22(18)12-15/h1-7,15-16H,8-13H2
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1.30E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279246
PNG
(CHEMBL499636 | N-(4-Phenylbutyl)cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCCCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C21H26N2O/c24-21-11-6-10-20-19-13-18(15-23(20)21)14-22(16-19)12-5-4-9-17-7-2-1-3-8-17/h1-3,6-8,10-11,18-19H,4-5,9,12-16H2
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2.22E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]cytisine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279277
PNG
(1-Phenyl-2-(cytisin-12-yl)-1-ethanone | CHEMBL5020...)
Show SMILES O=C(CN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2)c1ccccc1 |r|
Show InChI InChI=1S/C19H20N2O2/c22-18(15-5-2-1-3-6-15)13-20-10-14-9-16(12-20)17-7-4-8-19(23)21(17)11-14/h1-8,14,16H,9-13H2
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2.25E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279333
PNG
(3-(Cytisin-12-yl)propionamide | CHEMBL483804)
Show SMILES NC(=O)CCN1C[C@@H]2C[C@H](C1)c1cccc(=O)n1C2 |r|
Show InChI InChI=1S/C14H19N3O2/c15-13(18)4-5-16-7-10-6-11(9-16)12-2-1-3-14(19)17(12)8-10/h1-3,10-11H,4-9H2,(H2,15,18)
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3.60E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279246
PNG
(CHEMBL499636 | N-(4-Phenylbutyl)cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCCCc4ccccc4)C3)Cn12 |r|
Show InChI InChI=1S/C21H26N2O/c24-21-11-6-10-20-19-13-18(15-23(20)21)14-22(16-19)12-5-4-9-17-7-2-1-3-8-17/h1-3,6-8,10-11,18-19H,4-5,9,12-16H2
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3.90E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of (+/-)-[3H]epibatidine from alpha4beta2 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor


(Rattus norvegicus (Rat))
BDBM50279210
PNG
(CHEMBL525735 | N-[2-(Pyridin-4-yl)ethyl]cytisine)
Show SMILES O=c1cccc2[C@@H]3C[C@@H](CN(CCc4ccncc4)C3)Cn12 |r|
Show InChI InChI=1S/C18H21N3O/c22-18-3-1-2-17-16-10-15(12-21(17)18)11-20(13-16)9-6-14-4-7-19-8-5-14/h1-5,7-8,15-16H,6,9-13H2
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4.20E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Genova

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nicotinic acetylcholine receptor in rat brain cortex membrane homogenates


J Med Chem 52: 4345-57 (2009)


Article DOI: 10.1021/jm900225j
BindingDB Entry DOI: 10.7270/Q2K64J03
More data for this
Ligand-Target Pair
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