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Compile Data Set for Download or QSAR

Found 47 hits with Last Name = 'todd' and Initial = 'b'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50369584
PNG
(CHEMBL1790230)
Show SMILES CC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCNC1=O)cc2)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C
Show InChI InChI=1S/C43H54N6O6/c1-5-28(4)39-42(53)44-22-11-23-55-32-19-16-30(17-20-32)25-36(41(52)49-39)45-26-37(50)35(24-29-12-7-6-8-13-29)47-43(54)38(27(2)3)48-40(51)34-21-18-31-14-9-10-15-33(31)46-34/h6-10,12-21,27-28,35-39,45,50H,5,11,22-26H2,1-4H3,(H,44,53)(H,47,54)(H,48,51)(H,49,52)/t28-,35+,36+,37-,38+,39+/m1/s1
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0.300n/an/an/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibitory constant against HIV-1 protease


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092152
PNG
(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Show SMILES CCC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCCCNC1=O)cc2)NC[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Show InChI InChI=1S/C41H54N4O6/c1-3-27(2)37-41(50)42-20-10-5-11-21-51-33-18-16-29(17-19-33)23-35(40(49)44-37)43-26-32(46)24-31(22-28-12-6-4-7-13-28)39(48)45-38-34-15-9-8-14-30(34)25-36(38)47/h4,6-9,12-19,27,31-32,35-38,43,46-47H,3,5,10-11,20-26H2,1-2H3,(H,42,50)(H,44,49)(H,45,48)/t27?,31-,32+,35+,36-,37+,38+/m1/s1
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0.600n/an/an/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibitory constant against HIV-1 protease


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092151
PNG
((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Show SMILES CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C32H48N4O6S/c1-22(2)17-18-36(43(40,41)27-15-11-25(33)12-16-27)21-29(37)28-20-24-9-13-26(14-10-24)42-19-7-5-6-8-30(38)35-31(23(3)4)32(39)34-28/h9-16,22-23,28-29,31,37H,5-8,17-21,33H2,1-4H3,(H,34,39)(H,35,38)/t28-,29+,31-/m0/s1
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1.70n/an/an/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibitory constant against HIV-1 protease


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM577
PNG
((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...)
Show SMILES CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1 |r|
Show InChI InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1
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n/an/a 30n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092151
PNG
((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Show SMILES CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C32H48N4O6S/c1-22(2)17-18-36(43(40,41)27-15-11-25(33)12-16-27)21-29(37)28-20-24-9-13-26(14-10-24)42-19-7-5-6-8-30(38)35-31(23(3)4)32(39)34-28/h9-16,22-23,28-29,31,37H,5-8,17-21,33H2,1-4H3,(H,34,39)(H,35,38)/t28-,29+,31-/m0/s1
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n/an/a 45n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM517
PNG
((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)
Show SMILES CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r|
Show InChI InChI=1S/C36H47N5O4/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45)/t28-,29+,31+,32-,33+/m1/s1
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n/an/a 52n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in PBMC cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM517
PNG
((2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-h...)
Show SMILES CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r|
Show InChI InChI=1S/C36H47N5O4/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45)/t28-,29+,31+,32-,33+/m1/s1
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n/an/a 56n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092152
PNG
(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Show SMILES CCC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCCCNC1=O)cc2)NC[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Show InChI InChI=1S/C41H54N4O6/c1-3-27(2)37-41(50)42-20-10-5-11-21-51-33-18-16-29(17-19-33)23-35(40(49)44-37)43-26-32(46)24-31(22-28-12-6-4-7-13-28)39(48)45-38-34-15-9-8-14-30(34)25-36(38)47/h4,6-9,12-19,27,31-32,35-38,43,46-47H,3,5,10-11,20-26H2,1-2H3,(H,42,50)(H,44,49)(H,45,48)/t27?,31-,32+,35+,36-,37+,38+/m1/s1
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n/an/a 56n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092152
PNG
(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Show SMILES CCC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCCCNC1=O)cc2)NC[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Show InChI InChI=1S/C41H54N4O6/c1-3-27(2)37-41(50)42-20-10-5-11-21-51-33-18-16-29(17-19-33)23-35(40(49)44-37)43-26-32(46)24-31(22-28-12-6-4-7-13-28)39(48)45-38-34-15-9-8-14-30(34)25-36(38)47/h4,6-9,12-19,27,31-32,35-38,43,46-47H,3,5,10-11,20-26H2,1-2H3,(H,42,50)(H,44,49)(H,45,48)/t27?,31-,32+,35+,36-,37+,38+/m1/s1
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n/an/a 60n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells of HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092151
PNG
((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Show SMILES CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C32H48N4O6S/c1-22(2)17-18-36(43(40,41)27-15-11-25(33)12-16-27)21-29(37)28-20-24-9-13-26(14-10-24)42-19-7-5-6-8-30(38)35-31(23(3)4)32(39)34-28/h9-16,22-23,28-29,31,37H,5-8,17-21,33H2,1-4H3,(H,34,39)(H,35,38)/t28-,29+,31-/m0/s1
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n/an/a 90n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50369584
PNG
(CHEMBL1790230)
Show SMILES CC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCNC1=O)cc2)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C
Show InChI InChI=1S/C43H54N6O6/c1-5-28(4)39-42(53)44-22-11-23-55-32-19-16-30(17-20-32)25-36(41(52)49-39)45-26-37(50)35(24-29-12-7-6-8-13-29)47-43(54)38(27(2)3)48-40(51)34-21-18-31-14-9-10-15-33(31)46-34/h6-10,12-21,27-28,35-39,45,50H,5,11,22-26H2,1-4H3,(H,44,53)(H,47,54)(H,48,51)(H,49,52)/t28-,35+,36+,37-,38+,39+/m1/s1
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n/an/a 95n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092152
PNG
(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Show SMILES CCC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCCCNC1=O)cc2)NC[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Show InChI InChI=1S/C41H54N4O6/c1-3-27(2)37-41(50)42-20-10-5-11-21-51-33-18-16-29(17-19-33)23-35(40(49)44-37)43-26-32(46)24-31(22-28-12-6-4-7-13-28)39(48)45-38-34-15-9-8-14-30(34)25-36(38)47/h4,6-9,12-19,27,31-32,35-38,43,46-47H,3,5,10-11,20-26H2,1-2H3,(H,42,50)(H,44,49)(H,45,48)/t27?,31-,32+,35+,36-,37+,38+/m1/s1
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n/an/a 100n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-2 strain (ROD)


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM150
PNG
((4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis({...)
Show SMILES OCc1ccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3ccc(CO)cc3)C2=O)cc1
Show InChI InChI=1S/C35H38N2O5/c38-23-29-15-11-27(12-16-29)21-36-31(19-25-7-3-1-4-8-25)33(40)34(41)32(20-26-9-5-2-6-10-26)37(35(36)42)22-28-13-17-30(24-39)18-14-28/h1-18,31-34,38-41H,19-24H2/t31-,32-,33+,34+/m1/s1
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n/an/a 110n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in cord blood mononuclear cells (CBMC) infected with HIV -1 TC354...


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092152
PNG
(2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-dia...)
Show SMILES CCC(C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCCCNC1=O)cc2)NC[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12
Show InChI InChI=1S/C41H54N4O6/c1-3-27(2)37-41(50)42-20-10-5-11-21-51-33-18-16-29(17-19-33)23-35(40(49)44-37)43-26-32(46)24-31(22-28-12-6-4-7-13-28)39(48)45-38-34-15-9-8-14-30(34)25-36(38)47/h4,6-9,12-19,27,31-32,35-38,43,46-47H,3,5,10-11,20-26H2,1-2H3,(H,42,50)(H,44,49)(H,45,48)/t27?,31-,32+,35+,36-,37+,38+/m1/s1
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n/an/a 110n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in PBMC cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092151
PNG
((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Show SMILES CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C32H48N4O6S/c1-22(2)17-18-36(43(40,41)27-15-11-25(33)12-16-27)21-29(37)28-20-24-9-13-26(14-10-24)42-19-7-5-6-8-30(38)35-31(23(3)4)32(39)34-28/h9-16,22-23,28-29,31,37H,5-8,17-21,33H2,1-4H3,(H,34,39)(H,35,38)/t28-,29+,31-/m0/s1
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n/an/a 430n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in PBMC cells infected with HIV-1 237288 strain


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)
BDBM50092151
PNG
((10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENES...)
Show SMILES CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1ccc(N)cc1
Show InChI InChI=1S/C32H48N4O6S/c1-22(2)17-18-36(43(40,41)27-15-11-25(33)12-16-27)21-29(37)28-20-24-9-13-26(14-10-24)42-19-7-5-6-8-30(38)35-31(23(3)4)32(39)34-28/h9-16,22-23,28-29,31,37H,5-8,17-21,33H2,1-4H3,(H,34,39)(H,35,38)/t28-,29+,31-/m0/s1
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n/an/a 500n/an/an/an/an/an/a



The University of Queensland

Curated by ChEMBL


Assay Description
Inhibition of virion associated RT activity relative to untreated, infected control in MT2 cells infected with HIV-2 strain (ROD)


J Med Chem 43: 3495-504 (2000)


BindingDB Entry DOI: 10.7270/Q2KH0P1S
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59162
PNG
(8047577)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O
Show InChI InChI=1S/C21H10Cl2F3NO2S2/c22-12-4-6-15(16(23)9-12)17-7-5-14(29-17)10-18-19(28)27(20(30)31-18)13-3-1-2-11(8-13)21(24,25)26/h1-10H/b18-10-
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n/an/a 2.10E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59159
PNG
(6190013)
Show SMILES [#8-]-[#7+](=O)-c1cc(Cl)c(cc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C15H7Cl2N3O5S/c16-9-5-11(20(23)24)10(17)4-7(9)12-2-1-6(25-12)3-8-13(21)18-15(26)19-14(8)22/h1-5H,(H2,18,19,21,22,26)
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n/an/a 2.11E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59162
PNG
(8047577)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O
Show InChI InChI=1S/C21H10Cl2F3NO2S2/c22-12-4-6-15(16(23)9-12)17-7-5-14(29-17)10-18-19(28)27(20(30)31-18)13-3-1-2-11(8-13)21(24,25)26/h1-10H/b18-10-
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n/an/a 2.44E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59162
PNG
(8047577)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O
Show InChI InChI=1S/C21H10Cl2F3NO2S2/c22-12-4-6-15(16(23)9-12)17-7-5-14(29-17)10-18-19(28)27(20(30)31-18)13-3-1-2-11(8-13)21(24,25)26/h1-10H/b18-10-
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n/an/a 2.56E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59164
PNG
(8048422)
Show SMILES [#8-]-[#6](=O)-c1cc(ccc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C16H9ClN2O5S/c17-11-3-1-7(5-9(11)15(22)23)12-4-2-8(24-12)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 3.89E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59164
PNG
(8048422)
Show SMILES [#8-]-[#6](=O)-c1cc(ccc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C16H9ClN2O5S/c17-11-3-1-7(5-9(11)15(22)23)12-4-2-8(24-12)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 4.17E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59154
PNG
(5739991)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C14H7BrN2O4S2/c15-12-6-5-10(21-12)7-11-13(18)16(14(22)23-11)8-1-3-9(4-2-8)17(19)20/h1-7H/b11-7-
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n/an/a 4.63E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59163
PNG
(6789536)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C\c2ccc(Sc3ccc(Cl)cc3)o2)C1=O
Show InChI InChI=1S/C20H11ClN2O4S3/c21-12-1-8-16(9-2-12)29-18-10-7-15(27-18)11-17-19(24)22(20(28)30-17)13-3-5-14(6-4-13)23(25)26/h1-11H/b17-11+
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n/an/a 4.81E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59161
PNG
(5738875)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(I)o2)C1=O
Show InChI InChI=1S/C15H7F3INO2S2/c16-15(17,18)8-2-1-3-9(6-8)20-13(21)11(24-14(20)23)7-10-4-5-12(19)22-10/h1-7H/b11-7-
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n/an/a 5.00E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59163
PNG
(6789536)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C\c2ccc(Sc3ccc(Cl)cc3)o2)C1=O
Show InChI InChI=1S/C20H11ClN2O4S3/c21-12-1-8-16(9-2-12)29-18-10-7-15(27-18)11-17-19(24)22(20(28)30-17)13-3-5-14(6-4-13)23(25)26/h1-11H/b17-11+
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n/an/a 5.60E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59161
PNG
(5738875)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(I)o2)C1=O
Show InChI InChI=1S/C15H7F3INO2S2/c16-15(17,18)8-2-1-3-9(6-8)20-13(21)11(24-14(20)23)7-10-4-5-12(19)22-10/h1-7H/b11-7-
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n/an/a 5.65E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59163
PNG
(6789536)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C\c2ccc(Sc3ccc(Cl)cc3)o2)C1=O
Show InChI InChI=1S/C20H11ClN2O4S3/c21-12-1-8-16(9-2-12)29-18-10-7-15(27-18)11-17-19(24)22(20(28)30-17)13-3-5-14(6-4-13)23(25)26/h1-11H/b17-11+
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n/an/a 5.85E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59165
PNG
(8056354)
Show SMILES [#8-]-[#6](=O)-c1cccc(-c2ccc(\[#6]=[#6]-3/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-3=O)o2)c1Cl
Show InChI InChI=1S/C16H9ClN2O5S/c17-12-8(2-1-3-9(12)15(22)23)11-5-4-7(24-11)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 6.29E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59165
PNG
(8056354)
Show SMILES [#8-]-[#6](=O)-c1cccc(-c2ccc(\[#6]=[#6]-3/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-3=O)o2)c1Cl
Show InChI InChI=1S/C16H9ClN2O5S/c17-12-8(2-1-3-9(12)15(22)23)11-5-4-7(24-11)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 6.51E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59153
PNG
(5737176)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C15H7BrF3NO2S2/c16-12-5-4-10(22-12)7-11-13(21)20(14(23)24-11)9-3-1-2-8(6-9)15(17,18)19/h1-7H/b11-7-
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n/an/a 6.66E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59164
PNG
(8048422)
Show SMILES [#8-]-[#6](=O)-c1cc(ccc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C16H9ClN2O5S/c17-11-3-1-7(5-9(11)15(22)23)12-4-2-8(24-12)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 6.70E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59165
PNG
(8056354)
Show SMILES [#8-]-[#6](=O)-c1cccc(-c2ccc(\[#6]=[#6]-3/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-3=O)o2)c1Cl
Show InChI InChI=1S/C16H9ClN2O5S/c17-12-8(2-1-3-9(12)15(22)23)11-5-4-7(24-11)6-10-13(20)18-16(25)19-14(10)21/h1-6H,(H,22,23)(H2,18,19,20,21,25)/p-1
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n/an/a 6.80E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59161
PNG
(5738875)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(I)o2)C1=O
Show InChI InChI=1S/C15H7F3INO2S2/c16-15(17,18)8-2-1-3-9(6-8)20-13(21)11(24-14(20)23)7-10-4-5-12(19)22-10/h1-7H/b11-7-
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n/an/a 6.83E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59159
PNG
(6190013)
Show SMILES [#8-]-[#7+](=O)-c1cc(Cl)c(cc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C15H7Cl2N3O5S/c16-9-5-11(20(23)24)10(17)4-7(9)12-2-1-6(25-12)3-8-13(21)18-15(26)19-14(8)22/h1-5H,(H2,18,19,21,22,26)
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n/an/a 7.50E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59159
PNG
(6190013)
Show SMILES [#8-]-[#7+](=O)-c1cc(Cl)c(cc1Cl)-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)o1
Show InChI InChI=1S/C15H7Cl2N3O5S/c16-9-5-11(20(23)24)10(17)4-7(9)12-2-1-6(25-12)3-8-13(21)18-15(26)19-14(8)22/h1-5H,(H2,18,19,21,22,26)
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n/an/a 8.48E+3n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59153
PNG
(5737176)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C15H7BrF3NO2S2/c16-12-5-4-10(22-12)7-11-13(21)20(14(23)24-11)9-3-1-2-8(6-9)15(17,18)19/h1-7H/b11-7-
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n/an/a 8.50E+3n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59153
PNG
(5737176)
Show SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C15H7BrF3NO2S2/c16-12-5-4-10(22-12)7-11-13(21)20(14(23)24-11)9-3-1-2-8(6-9)15(17,18)19/h1-7H/b11-7-
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n/an/a 9.25E+3n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59154
PNG
(5739991)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C14H7BrN2O4S2/c15-12-6-5-10(21-12)7-11-13(18)16(14(22)23-11)8-1-3-9(4-2-8)17(19)20/h1-7H/b11-7-
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n/an/a 1.04E+4n/an/an/an/a8.0n/a



University of Washington



Assay Description
Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59154
PNG
(5739991)
Show SMILES [O-][N+](=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(Br)o2)C1=O
Show InChI InChI=1S/C14H7BrN2O4S2/c15-12-6-5-10(21-12)7-11-13(18)16(14(22)23-11)8-1-3-9(4-2-8)17(19)20/h1-7H/b11-7-
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n/an/a 1.17E+4n/an/an/an/a7.9n/a



University of Washington



Assay Description
Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59157
PNG
(6126765)
Show SMILES COc1cc(\C=C2\SC(=S)N(CC(=O)Nc3ccccn3)C2=O)cc(OC)c1OC
Show InChI InChI=1S/C20H19N3O5S2/c1-26-13-8-12(9-14(27-2)18(13)28-3)10-15-19(25)23(20(29)30-15)11-17(24)22-16-6-4-5-7-21-16/h4-10H,11H2,1-3H3,(H,21,22,24)/b15-10+
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n/an/a 1.19E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59160
PNG
(6209549)
Show SMILES COc1cc(C=Nn2c(O)csc2=S)ccc1OCCOc1ccc(cc1)C(C)(C)C |w:6.6|
Show InChI InChI=1S/C23H26N2O4S2/c1-23(2,3)17-6-8-18(9-7-17)28-11-12-29-19-10-5-16(13-20(19)27-4)14-24-25-21(26)15-31-22(25)30/h5-10,13-15,26H,11-12H2,1-4H3
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n/an/a 1.24E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59155
PNG
(5924029)
Show SMILES Fc1ccc(C=NNC(=N)NN=Cc2ccc(F)cc2)cc1 |w:11.10,6.6|
Show InChI InChI=1S/C15H13F2N5/c16-13-5-1-11(2-6-13)9-19-21-15(18)22-20-10-12-3-7-14(17)8-4-12/h1-10H,(H3,18,21,22)
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n/an/a 2.45E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59156
PNG
(6072484 | cid_726942)
Show SMILES CCOc1ccc(cc1)-c1cc(C)n2nc(cc2n1)C(N)=O
Show InChI InChI=1S/C16H16N4O2/c1-3-22-12-6-4-11(5-7-12)13-8-10(2)20-15(18-13)9-14(19-20)16(17)21/h4-9H,3H2,1-2H3,(H2,17,21)
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n/an/a 2.68E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59152
PNG
(5523453)
Show SMILES CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc2CC(C)CCc12
Show InChI InChI=1S/C20H22N2O3S2/c1-3-25-19(24)16-14-10-9-12(2)11-15(14)27-18(16)22-20(26)21-17(23)13-7-5-4-6-8-13/h4-8,12H,3,9-11H2,1-2H3,(H2,21,22,23,26)
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n/an/a 2.77E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59158
PNG
(6168356)
Show SMILES CCOc1ccc(Cl)cc1\C=C1\SC(=S)N(CC)C1=O
Show InChI InChI=1S/C14H14ClNO2S2/c1-3-16-13(17)12(20-14(16)19)8-9-7-10(15)5-6-11(9)18-4-2/h5-8H,3-4H2,1-2H3/b12-8+
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n/an/a 4.96E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair
Coagulation Factor VIII


(Homo sapiens (Human))
BDBM59151
PNG
(5247489)
Show SMILES CC(C=Cc1ccco1)=NCCCCNC(=O)C=Cc1ccco1 |w:18.19,9.10,2.1|
Show InChI InChI=1S/C19H22N2O3/c1-16(8-9-17-6-4-14-23-17)20-12-2-3-13-21-19(22)11-10-18-7-5-15-24-18/h4-11,14-15H,2-3,12-13H2,1H3,(H,21,22)
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n/an/a 5.61E+4n/an/an/an/an/a37



University of Washington



Assay Description
Inhibition of factor VIII C2 domain.


Chem Biol 11: 1413-22 (2004)


Article DOI: 10.1016/j.chembiol.2004.08.006
BindingDB Entry DOI: 10.7270/Q29W0CX1
More data for this
Ligand-Target Pair