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Compile Data Set for Download or QSAR

Found 5 hits with Last Name = 'tonus' and Initial = 'f'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50439334
PNG
(CHEMBL2419761)
Show SMILES C1COc2cc3c(Nc4cccc(c4)-c4ccccc4)ncnc3cc2O1
Show InChI InChI=1S/C22H17N3O2/c1-2-5-15(6-3-1)16-7-4-8-17(11-16)25-22-18-12-20-21(27-10-9-26-20)13-19(18)23-14-24-22/h1-8,11-14H,9-10H2,(H,23,24,25)
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n/an/a 24n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of Abl (unknown origin)


Eur J Med Chem 67: 373-83 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.057
BindingDB Entry DOI: 10.7270/Q2SN0BCC
More data for this
Ligand-Target Pair
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50439335
PNG
(CHEMBL2419760)
Show SMILES C1Oc2cc3ncnc(Nc4cccc(c4)-c4ccccc4)c3cc2O1
Show InChI InChI=1S/C21H15N3O2/c1-2-5-14(6-3-1)15-7-4-8-16(9-15)24-21-17-10-19-20(26-13-25-19)11-18(17)22-12-23-21/h1-12H,13H2,(H,22,23,24)
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n/an/a 51n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of Abl (unknown origin)


Eur J Med Chem 67: 373-83 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.057
BindingDB Entry DOI: 10.7270/Q2SN0BCC
More data for this
Ligand-Target Pair
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))
BDBM50439333
PNG
(CHEMBL2419762)
Show SMILES C1COc2cc3ncnc(Nc4cccc(c4)-c4ccccc4)c3cc2OC1
Show InChI InChI=1S/C23H19N3O2/c1-2-6-16(7-3-1)17-8-4-9-18(12-17)26-23-19-13-21-22(28-11-5-10-27-21)14-20(19)24-15-25-23/h1-4,6-9,12-15H,5,10-11H2,(H,24,25,26)
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n/an/a 56n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of Abl (unknown origin)


Eur J Med Chem 67: 373-83 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.057
BindingDB Entry DOI: 10.7270/Q2SN0BCC
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50439334
PNG
(CHEMBL2419761)
Show SMILES C1COc2cc3c(Nc4cccc(c4)-c4ccccc4)ncnc3cc2O1
Show InChI InChI=1S/C22H17N3O2/c1-2-5-15(6-3-1)16-7-4-8-17(11-16)25-22-18-12-20-21(27-10-9-26-20)13-19(18)23-14-24-22/h1-8,11-14H,9-10H2,(H,23,24,25)
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n/an/a 100n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin)


Eur J Med Chem 67: 373-83 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.057
BindingDB Entry DOI: 10.7270/Q2SN0BCC
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50439335
PNG
(CHEMBL2419760)
Show SMILES C1Oc2cc3ncnc(Nc4cccc(c4)-c4ccccc4)c3cc2O1
Show InChI InChI=1S/C21H15N3O2/c1-2-5-14(6-3-1)15-7-4-8-16(9-15)24-21-17-10-19-20(26-13-25-19)11-18(17)22-12-23-21/h1-12H,13H2,(H,22,23,24)
PDB
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NCI pathway
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n/an/a 243n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin)


Eur J Med Chem 67: 373-83 (2013)


Article DOI: 10.1016/j.ejmech.2013.06.057
BindingDB Entry DOI: 10.7270/Q2SN0BCC
More data for this
Ligand-Target Pair