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Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'van der graaf' and Initial = 'p'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50039676
PNG
(4-Fluorosulfonyl-benzoic acid 3-(8-cyclopentyl-2,6...)
Show SMILES CCCn1c(=O)n(CCCOC(=O)c2ccc(cc2)S(F)(=O)=O)c2nc([nH]c2c1=O)C1CCCC1
Show InChI InChI=1S/C23H27FN4O6S/c1-2-12-28-21(29)18-20(26-19(25-18)15-6-3-4-7-15)27(23(28)31)13-5-14-34-22(30)16-8-10-17(11-9-16)35(24,32)33/h8-11,15H,2-7,12-14H2,1H3,(H,25,26)
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12n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Binding affinity towards rat Adenosine A1 receptor using [3H]-DPCPX


Bioorg Med Chem Lett 11: 815-8 (2001)


BindingDB Entry DOI: 10.7270/Q2TB17FM
More data for this
Ligand-Target Pair
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM25400
PNG
((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12
Show InChI InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
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230n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Binding affinity towards rat Adenosine A1 receptor using [3H]-DPCPX


Bioorg Med Chem Lett 11: 815-8 (2001)


BindingDB Entry DOI: 10.7270/Q2TB17FM
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50197517
PNG
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 0.600n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rat NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50197517
PNG
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 0.800n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rabbit NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197517
PNG
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 2.30n/an/an/an/a7.0n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197513
PNG
((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C22H31NO5/c1-28-11-8-18(19(25)26)12-21(9-4-5-10-21)20(27)23-22(15-24)13-16-6-2-3-7-17(16)14-22/h2-3,6-7,18,24H,4-5,8-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1
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n/an/a 3.70n/an/an/an/a7.0n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197519
PNG
((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C21H30FNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 4.60n/an/an/an/a7.0n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197517
PNG
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 5.40n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197507
PNG
((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)N[C@@H]1C[C@H]1c1ccc(OC)cc1)C(O)=O
Show InChI InChI=1S/C22H31NO5/c1-27-12-9-16(20(24)25)14-22(10-3-4-11-22)21(26)23-19-13-18(19)15-5-7-17(28-2)8-6-15/h5-8,16,18-19H,3-4,9-14H2,1-2H3,(H,23,26)(H,24,25)/t16-,18+,19-/m1/s1
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n/an/a 6.10n/an/an/an/a7.0n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197513
PNG
((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C22H31NO5/c1-28-11-8-18(19(25)26)12-21(9-4-5-10-21)20(27)23-22(15-24)13-16-6-2-3-7-17(16)14-22/h2-3,6-7,18,24H,4-5,8-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1
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n/an/a 10n/an/an/an/a7.4n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7.4


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 10.2n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rabbit NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Oryctolagus cuniculus (rabbit))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 10.2n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rabbit NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197517
PNG
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C21H30ClNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 10.5n/an/an/an/a7.4n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7.4


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190771
PNG
((R)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)/t18-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197519
PNG
((S)-2-{1-[3-(4-fluoro-phenyl)-propylcarbamoyl]-cyc...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)NCCCc1ccc(F)cc1)C(O)=O
Show InChI InChI=1S/C21H30FNO4/c1-27-14-10-17(19(24)25)15-21(11-2-3-12-21)20(26)23-13-4-5-16-6-8-18(22)9-7-16/h6-9,17H,2-5,10-15H2,1H3,(H,23,26)(H,24,25)/t17-/m1/s1
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n/an/a 12.6n/an/an/an/a7.4n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7.4


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50197507
PNG
((S)-4-methoxy-2-{1-[(1R,2S)-2-(4-methoxy-phenyl)-c...)
Show SMILES COCC[C@H](CC1(CCCC1)C(=O)N[C@@H]1C[C@H]1c1ccc(OC)cc1)C(O)=O
Show InChI InChI=1S/C22H31NO5/c1-27-12-9-16(20(24)25)14-22(10-3-4-11-22)21(26)23-19-13-18(19)15-5-7-17(28-2)8-6-15/h5-8,16,18-19H,3-4,9-14H2,1-2H3,(H,23,26)(H,24,25)/t16-,18+,19-/m1/s1
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n/an/a 13.8n/an/an/an/a7.4n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7.4


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 14.3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rat NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neutral Endopeptidase (NEP)


(Rattus norvegicus (Rat))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 14.3n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of rat NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 18.9n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 18.9n/an/an/an/a7.0n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 19.7n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NEP


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 19.7n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 26n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190753
PNG
(2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(Cc2ccccc2)s1)C(O)=O
Show InChI InChI=1S/C21H27N3O3S/c1-2-8-16(18(25)26)14-21(11-6-7-12-21)19(27)22-20-24-23-17(28-20)13-15-9-4-3-5-10-15/h3-5,9-10,16H,2,6-8,11-14H2,1H3,(H,25,26)(H,22,24,27)
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n/an/a 30n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190746
PNG
((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1
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n/an/a 31.8n/an/an/an/a7.4n/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human kidney NEP at pH 7.4


Bioorg Med Chem 15: 142-59 (2006)


Article DOI: 10.1016/j.bmc.2006.10.002
BindingDB Entry DOI: 10.7270/Q2ZS2W4J
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190762
PNG
(2-((1-((5-(cyclopropylmethyl)-1,3,4-thiadiazol-2-y...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC2CC2)s1)C(O)=O
Show InChI InChI=1S/C18H27N3O3S/c1-2-5-13(15(22)23)11-18(8-3-4-9-18)16(24)19-17-21-20-14(25-17)10-12-6-7-12/h12-13H,2-11H2,1H3,(H,22,23)(H,19,21,24)
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n/an/a 38n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190737
PNG
(2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...)
Show SMILES CCc1nnc(NC(=O)C2(CC(CCc3ccccc3)C(O)=O)CCCC2)s1
Show InChI InChI=1S/C21H27N3O3S/c1-2-17-23-24-20(28-17)22-19(27)21(12-6-7-13-21)14-16(18(25)26)11-10-15-8-4-3-5-9-15/h3-5,8-9,16H,2,6-7,10-14H2,1H3,(H,25,26)(H,22,24,27)
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n/an/a 46n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190773
PNG
(2-[1-(5-ethyl-[1,3,4]thiadiazol-2-ylcarbamoyl)-cyc...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)
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n/an/a 60n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190752
PNG
(2-((1-((1-ethyl-1H-1,2,3-triazol-4-yl)carbamoyl)cy...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cn(CC)nn1)C(O)=O
Show InChI InChI=1S/C16H26N4O3/c1-3-7-12(14(21)22)10-16(8-5-6-9-16)15(23)17-13-11-20(4-2)19-18-13/h11-12H,3-10H2,1-2H3,(H,17,23)(H,21,22)
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n/an/a 82n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190764
PNG
(2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...)
Show SMILES CCCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C17H27N3O3S/c1-3-5-8-12(14(21)22)11-17(9-6-7-10-17)15(23)18-16-20-19-13(4-2)24-16/h12H,3-11H2,1-2H3,(H,21,22)(H,18,20,23)
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n/an/a 84n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190750
PNG
(2-((1-((4-benzylpyridin-2-yl)carbamoyl)cyclopentyl...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1cc(Cc2ccccc2)ccn1)C(O)=O
Show InChI InChI=1S/C24H30N2O3/c1-2-8-20(22(27)28)17-24(12-6-7-13-24)23(29)26-21-16-19(11-14-25-21)15-18-9-4-3-5-10-18/h3-5,9-11,14,16,20H,2,6-8,12-13,15,17H2,1H3,(H,27,28)(H,25,26,29)
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n/an/a 96n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190769
PNG
(CHEMBL377037 | rac-2-((1-((2-(hydroxymethyl)-2,3-d...)
Show SMILES CCCC(CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)
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n/an/a 96n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190739
PNG
((R)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...)
Show SMILES CCC[C@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O
Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)/t11-/m1/s1
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n/an/a 114n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190738
PNG
(2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cy...)
Show SMILES CCc1nnc(NC(=O)C2(CC(CCC(C)C)C(O)=O)CCCC2)s1
Show InChI InChI=1S/C18H29N3O3S/c1-4-14-20-21-17(25-14)19-16(24)18(9-5-6-10-18)11-13(15(22)23)8-7-12(2)3/h12-13H,4-11H2,1-3H3,(H,22,23)(H,19,21,24)
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n/an/a 120n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190758
PNG
(2-((1-((5-isobutyl-1,3,4-thiadiazol-2-yl)carbamoyl...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC(C)C)s1)C(O)=O
Show InChI InChI=1S/C18H29N3O3S/c1-4-7-13(15(22)23)11-18(8-5-6-9-18)16(24)19-17-21-20-14(25-17)10-12(2)3/h12-13H,4-11H2,1-3H3,(H,22,23)(H,19,21,24)
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n/an/a 124n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190757
PNG
(CHEMBL439508 | cis-2-((1-((4-carbamoylcyclohexyl)c...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(N)=O)C(O)=O |wU:13.13,16.20,(-5.69,-23.39,;-5.69,-24.93,;-4.36,-25.7,;-4.36,-27.24,;-3.03,-28.01,;-1.69,-27.24,;-2.94,-26.34,;-2.46,-24.87,;-.92,-24.87,;-.45,-26.34,;-.36,-28.01,;-.36,-29.55,;.97,-27.24,;2.31,-28.01,;3.63,-27.24,;4.97,-28.02,;4.96,-29.56,;3.62,-30.32,;2.3,-29.55,;6.29,-30.33,;7.63,-29.57,;6.29,-31.87,;-5.69,-28.01,;-7.03,-27.24,;-5.69,-29.55,)|
Show InChI InChI=1S/C19H32N2O4/c1-2-5-14(17(23)24)12-19(10-3-4-11-19)18(25)21-15-8-6-13(7-9-15)16(20)22/h13-15H,2-12H2,1H3,(H2,20,22)(H,21,25)(H,23,24)/t13-,14?,15+
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n/an/a 150n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190761
PNG
(CHEMBL209493 | rac-2-((1-((5-methyl-1,3,4-thiadiaz...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O
Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)
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n/an/a 176n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190780
PNG
(2-((1-((4-butylpyridin-2-yl)carbamoyl)cyclopentyl)...)
Show SMILES CCCCc1ccnc(NC(=O)C2(CC(CCC)C(O)=O)CCCC2)c1
Show InChI InChI=1S/C21H32N2O3/c1-3-5-9-16-10-13-22-18(14-16)23-20(26)21(11-6-7-12-21)15-17(8-4-2)19(24)25/h10,13-14,17H,3-9,11-12,15H2,1-2H3,(H,24,25)(H,22,23,26)
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n/an/a 184n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190777
PNG
(2-((1-(((1R,2R)-2-benzylcyclohexyl)carbamoyl)cyclo...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CCCC[C@@H]1Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C25H37NO3/c1-2-10-21(23(27)28)18-25(15-8-9-16-25)24(29)26-22-14-7-6-13-20(22)17-19-11-4-3-5-12-19/h3-5,11-12,20-22H,2,6-10,13-18H2,1H3,(H,26,29)(H,27,28)/t20-,21?,22-/m1/s1
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n/an/a 195n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190743
PNG
((S)-2-((1-((2-(hydroxymethyl)-2,3-dihydro-1H-inden...)
Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)NC1(CO)Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C22H31NO4/c1-2-7-18(19(25)26)12-21(10-5-6-11-21)20(27)23-22(15-24)13-16-8-3-4-9-17(16)14-22/h3-4,8-9,18,24H,2,5-7,10-15H2,1H3,(H,23,27)(H,25,26)/t18-/m0/s1
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n/an/a 205n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190782
PNG
(2-((1-(((1R,3S)-3-carbamoylcyclopentyl)carbamoyl)c...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@@H]1CC[C@@H](C1)C(N)=O)C(O)=O
Show InChI InChI=1S/C18H30N2O4/c1-2-5-13(16(22)23)11-18(8-3-4-9-18)17(24)20-14-7-6-12(10-14)15(19)21/h12-14H,2-11H2,1H3,(H2,19,21)(H,20,24)(H,22,23)/t12-,13?,14+/m0/s1
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190763
PNG
(3-(1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cyc...)
Show SMILES CCc1nnc(NC(=O)C2(CCC(O)=O)CCCC2)s1
Show InChI InChI=1S/C13H19N3O3S/c1-2-9-15-16-12(20-9)14-11(19)13(6-3-4-7-13)8-5-10(17)18/h2-8H2,1H3,(H,17,18)(H,14,16,19)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190775
PNG
(2-((1-((5-phenyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1nnc(s1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C20H25N3O3S/c1-2-8-15(17(24)25)13-20(11-6-7-12-20)18(26)21-19-23-22-16(27-19)14-9-4-3-5-10-14/h3-5,9-10,15H,2,6-8,11-13H2,1H3,(H,24,25)(H,21,23,26)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190742
PNG
((S)-2-((1-((5-methyl-1,3,4-thiadiazol-2-yl)carbamo...)
Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)Nc1nnc(C)s1)C(O)=O
Show InChI InChI=1S/C15H23N3O3S/c1-3-6-11(12(19)20)9-15(7-4-5-8-15)13(21)16-14-18-17-10(2)22-14/h11H,3-9H2,1-2H3,(H,19,20)(H,16,18,21)/t11-/m0/s1
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190736
PNG
((S)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Show SMILES CCC[C@@H](CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O
Show InChI InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m0/s1
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190767
PNG
(2-((1-((3-(dimethylcarbamoyl)cyclohexyl)carbamoyl)...)
Show SMILES CCCC(CC1(CCCC1)C(=O)NC1CCCC(C1)C(=O)N(C)C)C(O)=O
Show InChI InChI=1S/C21H36N2O4/c1-4-8-16(19(25)26)14-21(11-5-6-12-21)20(27)22-17-10-7-9-15(13-17)18(24)23(2)3/h15-17H,4-14H2,1-3H3,(H,22,27)(H,25,26)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190755
PNG
(2-((1-((2,3-dihydro-1H-inden-2-yl)carbamoyl)cyclop...)
Show SMILES CCCC(CC1(CCCC1)C(=O)NC1Cc2ccccc2C1)C(O)=O
Show InChI InChI=1S/C21H29NO3/c1-2-7-17(19(23)24)14-21(10-5-6-11-21)20(25)22-18-12-15-8-3-4-9-16(15)13-18/h3-4,8-9,17-18H,2,5-7,10-14H2,1H3,(H,22,25)(H,23,24)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190760
PNG
(2-((1-((1-benzyl-6-oxo-1,6-dihydropyridin-3-yl)car...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1ccc(=O)n(Cc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C24H30N2O4/c1-2-8-19(22(28)29)15-24(13-6-7-14-24)23(30)25-20-11-12-21(27)26(17-20)16-18-9-4-3-5-10-18/h3-5,9-12,17,19H,2,6-8,13-16H2,1H3,(H,25,30)(H,28,29)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190772
PNG
(CHEMBL213240 | cis-2-((1-((4-(dimethylcarbamoyl)cy...)
Show SMILES CCCC(CC1(CCCC1)C(=O)N[C@H]1CC[C@H](CC1)C(=O)N(C)C)C(O)=O |wU:13.13,16.20,(-6.79,-6.07,;-6.79,-7.61,;-5.46,-8.38,;-5.46,-9.92,;-4.12,-10.69,;-2.79,-9.92,;-4.04,-9.02,;-3.56,-7.55,;-2.02,-7.55,;-1.54,-9.02,;-1.46,-10.69,;-1.46,-12.23,;-.12,-9.92,;1.21,-10.69,;2.53,-9.92,;3.87,-10.7,;3.87,-12.24,;2.53,-13,;1.2,-12.23,;5.2,-13.02,;5.19,-14.56,;6.53,-12.25,;7.86,-13.03,;6.54,-10.71,;-6.79,-10.69,;-8.12,-9.92,;-6.79,-12.23,)|
Show InChI InChI=1S/C21H36N2O4/c1-4-7-16(19(25)26)14-21(12-5-6-13-21)20(27)22-17-10-8-15(9-11-17)18(24)23(2)3/h15-17H,4-14H2,1-3H3,(H,22,27)(H,25,26)/t15-,16?,17+
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n/an/a 370n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
Neprilysin


(Homo sapiens (Human))
BDBM50190766
PNG
(2-((1-((6-methoxypyridazin-3-yl)carbamoyl)cyclopen...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1ccc(OC)nn1)C(O)=O
Show InChI InChI=1S/C17H25N3O4/c1-3-6-12(15(21)22)11-17(9-4-5-10-17)16(23)18-13-7-8-14(24-2)20-19-13/h7-8,12H,3-6,9-11H2,1-2H3,(H,21,22)(H,18,19,23)
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Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP


J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair
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