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Compile Data Set for Download or QSAR

Found 142 hits with Last Name = 'whitesides' and Initial = 'gm'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288900
PNG
((2-{2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]-a...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(O)=O
Show InChI InChI=1S/C15H19N5O8S/c16-29(27,28)10-3-1-9(2-4-10)15(26)20-7-13(23)18-5-11(21)17-6-12(22)19-8-14(24)25/h1-4H,5-8H2,(H,17,21)(H,18,23)(H,19,22)(H,20,26)(H,24,25)(H2,16,27,28)
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n/an/an/an/an/an/a 2.50E+5n/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for binding human carbonic anhydrase II (Kon=Kd x Koff)


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288892
PNG
(2-(4-Sulfamoyl-benzoylamino)-hexanoic acid | CHEMB...)
Show SMILES CCCCC(NC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C13H18N2O5S/c1-2-3-4-11(13(17)18)15-12(16)9-5-7-10(8-6-9)21(14,19)20/h5-8,11H,2-4H2,1H3,(H,15,16)(H,17,18)(H2,14,19,20)
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n/an/an/an/an/an/a 0.0220n/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for binding human carbonic anhydrase II (Kon=Kd x Koff)


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288910
PNG
(3-(4-Chloro-phenyl)-2-{2-[2-(4-sulfamoyl-benzoylam...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(O)=O |r|
Show InChI InChI=1S/C22H24ClN5O8S/c23-15-5-1-13(2-6-15)9-17(22(33)34)28-20(31)12-26-18(29)10-25-19(30)11-27-21(32)14-3-7-16(8-4-14)37(24,35)36/h1-8,17H,9-12H2,(H,25,30)(H,26,29)(H,27,32)(H,28,31)(H,33,34)(H2,24,35,36)/t17-/m0/s1
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n/an/an/a 96n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288878
PNG
(3-(4-Chloro-phenyl)-2-(4-sulfamoyl-benzoylamino)-p...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C16H15ClN2O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9H2,(H,19,20)(H,21,22)(H2,18,23,24)
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n/an/an/a 14n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288870
PNG
(2-(2-{2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]...)
Show SMILES CCCC[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C19H27N5O8S/c1-2-3-4-14(19(29)30)24-17(27)11-22-15(25)9-21-16(26)10-23-18(28)12-5-7-13(8-6-12)33(20,31)32/h5-8,14H,2-4,9-11H2,1H3,(H,21,26)(H,22,25)(H,23,28)(H,24,27)(H,29,30)(H2,20,31,32)/t14-/m0/s1
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n/an/an/an/an/a 0.0930n/an/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for binding human carbonic anhydrase II


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50101343
PNG
((4-Sulfamoyl-benzoylamino)-acetic acid | CHEMBL513...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C9H10N2O5S/c10-17(15,16)7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)(H2,10,15,16)
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n/an/an/an/an/an/a 3.61E+7n/an/a



TBA

Curated by ChEMBL


Assay Description
Kinetic constant for binding human carbonic anhydrase II (Kon=Kd x Koff)


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038950
PNG
(CHEMBL303188 | [2-(4-Sulfamoyl-benzoylamino)-acety...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)OCc1ccccc1
Show InChI InChI=1S/C18H19N3O6S/c19-28(25,26)15-8-6-14(7-9-15)18(24)21-10-16(22)20-11-17(23)27-12-13-4-2-1-3-5-13/h1-9H,10-12H2,(H,20,22)(H,21,24)(H2,19,25,26)
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n/an/an/a 71n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038951
PNG
(CHEMBL63189 | N-Pyridin-3-ylmethyl-4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1cccnc1
Show InChI InChI=1S/C13H13N3O3S/c14-20(18,19)12-5-3-11(4-6-12)13(17)16-9-10-2-1-7-15-8-10/h1-8H,9H2,(H,16,17)(H2,14,18,19)
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n/an/an/a 4n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038953
PNG
(CHEMBL67475 | N-Pyridin-4-ylmethyl-4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C13H13N3O3S/c14-20(18,19)12-3-1-11(2-4-12)13(17)16-9-10-5-7-15-8-6-10/h1-8H,9H2,(H,16,17)(H2,14,18,19)
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n/an/an/a 1.40n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038952
PNG
(4-Sulfamoyl-benzamide | CHEMBL67797)
Show SMILES NC(=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C7H8N2O3S/c8-7(10)5-1-3-6(4-2-5)13(9,11)12/h1-4H,(H2,8,10)(H2,9,11,12)
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n/an/an/a 120n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038954
PNG
(CHEMBL67854 | {2-[(R)-3-Phenyl-2-(4-sulfamoyl-benz...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)OCc1ccccc1
Show InChI InChI=1S/C27H28N4O7S/c28-39(36,37)22-13-11-21(12-14-22)26(34)31-23(15-19-7-3-1-4-8-19)27(35)30-16-24(32)29-17-25(33)38-18-20-9-5-2-6-10-20/h1-14,23H,15-18H2,(H,29,32)(H,30,35)(H,31,34)(H2,28,36,37)/t23-/m1/s1
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n/an/an/a 36n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038955
PNG
(CHEMBL65268 | N-(2-Methyl-benzyl)-4-sulfamoyl-benz...)
Show SMILES Cc1ccccc1CNC(=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H16N2O3S/c1-11-4-2-3-5-13(11)10-17-15(18)12-6-8-14(9-7-12)21(16,19)20/h2-9H,10H2,1H3,(H,17,18)(H2,16,19,20)
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n/an/an/a 2.20n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038957
PNG
(CHEMBL65213 | N-Pyridin-2-ylmethyl-4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccn1
Show InChI InChI=1S/C13H13N3O3S/c14-20(18,19)12-6-4-10(5-7-12)13(17)16-9-11-3-1-2-8-15-11/h1-8H,9H2,(H,16,17)(H2,14,18,19)
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n/an/an/a 4.30n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM12020
PNG
(2,3,4-trifluoro-SBB | 4-(AMINOSULFONYL)-N-[(2,3,4-...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccc(F)c(F)c1F
Show InChI InChI=1S/C14H11F3N2O3S/c15-11-6-3-9(12(16)13(11)17)7-19-14(20)8-1-4-10(5-2-8)23(18,21)22/h1-6H,7H2,(H,19,20)(H2,18,21,22)
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n/an/an/a 2.30n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038956
PNG
(CHEMBL63926 | {2-[(S)-2-Phenyl-2-(4-sulfamoyl-benz...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)OCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H26N4O7S/c27-38(35,36)21-13-11-20(12-14-21)25(33)30-24(19-9-5-2-6-10-19)26(34)29-15-22(31)28-16-23(32)37-17-18-7-3-1-4-8-18/h1-14,24H,15-17H2,(H,28,31)(H,29,34)(H,30,33)(H2,27,35,36)/t24-/m0/s1
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n/an/an/a 0.900n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038958
PNG
(CHEMBL63627 | N-(4-Dimethylamino-benzyl)-4-sulfamo...)
Show SMILES CN(C)c1ccc(CNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C16H19N3O3S/c1-19(2)14-7-3-12(4-8-14)11-18-16(20)13-5-9-15(10-6-13)23(17,21)22/h3-10H,11H2,1-2H3,(H,18,20)(H2,17,21,22)
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n/an/an/a 1.40n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038959
PNG
(CHEMBL433456 | {2-[(S)-3-Phenyl-2-(4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)OCc1ccccc1
Show InChI InChI=1S/C27H28N4O7S/c28-39(36,37)22-13-11-21(12-14-22)26(34)31-23(15-19-7-3-1-4-8-19)27(35)30-16-24(32)29-17-25(33)38-18-20-9-5-2-6-10-20/h1-14,23H,15-18H2,(H,29,32)(H,30,35)(H,31,34)(H2,28,36,37)/t23-/m0/s1
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n/an/an/a 5.30n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038961
PNG
(CHEMBL67676 | N-Methyl-4-sulfamoyl-benzamide)
Show SMILES CNC(=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C8H10N2O3S/c1-10-8(11)6-2-4-7(5-3-6)14(9,12)13/h2-5H,1H3,(H,10,11)(H2,9,12,13)
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n/an/an/a 150n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038960
PNG
(CHEMBL302587 | {2-[(S)-3-Phenyl-2-(4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(O)=O
Show InChI InChI=1S/C20H22N4O7S/c21-32(30,31)15-8-6-14(7-9-15)19(28)24-16(10-13-4-2-1-3-5-13)20(29)23-11-17(25)22-12-18(26)27/h1-9,16H,10-12H2,(H,22,25)(H,23,29)(H,24,28)(H,26,27)(H2,21,30,31)/t16-/m0/s1
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n/an/an/a 21n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038962
PNG
(CHEMBL302105 | N-Adamantan-1-ylmethyl-4-sulfamoyl-...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:17:18:22:16.15.21,21:20:23:16.15.17,21:16:23:20.22.19,THB:17:16:22:18.23.19,19:20:15:18.23.17,19:18:15:20.22.21|
Show InChI InChI=1S/C18H24N2O3S/c19-24(22,23)16-3-1-15(2-4-16)17(21)20-11-18-8-12-5-13(9-18)7-14(6-12)10-18/h1-4,12-14H,5-11H2,(H,20,21)(H2,19,22,23)
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n/an/an/a 2.10n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038963
PNG
(CHEMBL67687 | {2-[2-(4-Sulfamoyl-benzoylamino)-ace...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)NCC(=O)OCc1ccccc1
Show InChI InChI=1S/C20H22N4O7S/c21-32(29,30)16-8-6-15(7-9-16)20(28)24-11-18(26)22-10-17(25)23-12-19(27)31-13-14-4-2-1-3-5-14/h1-9H,10-13H2,(H,22,26)(H,23,25)(H,24,28)(H2,21,29,30)
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n/an/an/a 75n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038965
PNG
(CHEMBL63396 | N-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Pen...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Show InChI InChI=1S/C15H9F15N2O3S/c16-9(17,5-32-8(33)6-1-3-7(4-2-6)36(31,34)35)10(18,19)11(20,21)12(22,23)13(24,25)14(26,27)15(28,29)30/h1-4H,5H2,(H,32,33)(H2,31,34,35)
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n/an/an/a 0.300n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038964
PNG
(CHEMBL294548 | N-Octyl-4-sulfamoyl-benzamide)
Show SMILES CCCCCCCCNC(=O)c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H24N2O3S/c1-2-3-4-5-6-7-12-17-15(18)13-8-10-14(11-9-13)21(16,19)20/h8-11H,2-7,12H2,1H3,(H,17,18)(H2,16,19,20)
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n/an/an/a 2.5n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038966
PNG
(CHEMBL293628 | N-Cyclohexylmethyl-4-sulfamoyl-benz...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC1CCCCC1
Show InChI InChI=1S/C14H20N2O3S/c15-20(18,19)13-8-6-12(7-9-13)14(17)16-10-11-4-2-1-3-5-11/h6-9,11H,1-5,10H2,(H,16,17)(H2,15,18,19)
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n/an/an/a 1.10n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM12013
PNG
(4-(AMINOSULFONYL)-N-PHENYLMETHYLBENZAMIDE | CHEMBL...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)14(17)16-10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19)
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n/an/an/a 1.10n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038967
PNG
(CHEMBL65489 | N-Phenylsulfanylmethyl-4-sulfamoyl-b...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCSc1ccccc1
Show InChI InChI=1S/C14H14N2O3S2/c15-21(18,19)13-8-6-11(7-9-13)14(17)16-10-20-12-4-2-1-3-5-12/h1-9H,10H2,(H,16,17)(H2,15,18,19)
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n/an/an/a 1.70n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038971
PNG
(CHEMBL305376 | N-(4-Nitro-benzyl)-4-sulfamoyl-benz...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C14H13N3O5S/c15-23(21,22)13-7-3-11(4-8-13)14(18)16-9-10-1-5-12(6-2-10)17(19)20/h1-8H,9H2,(H,16,18)(H2,15,21,22)
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n/an/an/a 2n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038970
PNG
(CHEMBL63626 | N-(Furan-2-carbonyl)-4-sulfamoyl-ben...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NC(=O)c1ccco1
Show InChI InChI=1S/C12H10N2O5S/c13-20(17,18)9-5-3-8(4-6-9)11(15)14-12(16)10-2-1-7-19-10/h1-7H,(H2,13,17,18)(H,14,15,16)
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n/an/an/a 5.60n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038969
PNG
((2-{2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]-a...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)OCc1ccccc1
Show InChI InChI=1S/C22H25N5O8S/c23-36(33,34)17-8-6-16(7-9-17)22(32)27-12-20(30)25-10-18(28)24-11-19(29)26-13-21(31)35-14-15-4-2-1-3-5-15/h1-9H,10-14H2,(H,24,28)(H,25,30)(H,26,29)(H,27,32)(H2,23,33,34)
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n/an/an/a 210n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038968
PNG
(CHEMBL293626 | N-Naphthalen-1-ylmethyl-4-sulfamoyl...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1cccc2ccccc12
Show InChI InChI=1S/C18H16N2O3S/c19-24(22,23)16-10-8-14(9-11-16)18(21)20-12-15-6-3-5-13-4-1-2-7-17(13)15/h1-11H,12H2,(H,20,21)(H2,19,22,23)
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n/an/an/a 0.600n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50038972
PNG
(CHEMBL304720 | {2-[2-(4-Sulfamoyl-benzoylamino)-ac...)
Show SMILES CCCCc1ccc(COC(=O)CNC(=O)CNC(=O)CNC(=O)c2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C24H30N4O7S/c1-2-3-4-17-5-7-18(8-6-17)16-35-23(31)15-27-21(29)13-26-22(30)14-28-24(32)19-9-11-20(12-10-19)36(25,33)34/h5-12H,2-4,13-16H2,1H3,(H,26,30)(H,27,29)(H,28,32)(H2,25,33,34)
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n/an/an/a 53n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM10880
PNG
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O
Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
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n/an/an/a 6.80n/an/an/an/an/a



Harvard University

Curated by ChEMBL


Assay Description
Dissociation constant against human Carbonic anhydrase II (HCA II)


J Med Chem 37: 2100-5 (1994)


BindingDB Entry DOI: 10.7270/Q2TX3DDV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288856
PNG
(3-(4-Amino-phenyl)-2-(4-sulfamoyl-benzoylamino)-pr...)
Show SMILES Nc1ccc(CC(NC(=O)c2ccc(cc2)S(N)(=O)=O)C(O)=O)cc1
Show InChI InChI=1S/C16H17N3O5S/c17-12-5-1-10(2-6-12)9-14(16(21)22)19-15(20)11-3-7-13(8-4-11)25(18,23)24/h1-8,14H,9,17H2,(H,19,20)(H,21,22)(H2,18,23,24)
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n/an/an/a 64n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288857
PNG
(3-(4-Chloro-phenyl)-2-[2-(4-sulfamoyl-benzoylamino...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(Cc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C18H18ClN3O6S/c19-13-5-1-11(2-6-13)9-15(18(25)26)22-16(23)10-21-17(24)12-3-7-14(8-4-12)29(20,27)28/h1-8,15H,9-10H2,(H,21,24)(H,22,23)(H,25,26)(H2,20,27,28)
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n/an/an/a 100n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288858
PNG
(3-Methyl-2-{2-[2-(4-sulfamoyl-benzoylamino)-acetyl...)
Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C17H24N4O7S/c1-3-10(2)15(17(25)26)21-14(23)9-19-13(22)8-20-16(24)11-4-6-12(7-5-11)29(18,27)28/h4-7,10,15H,3,8-9H2,1-2H3,(H,19,22)(H,20,24)(H,21,23)(H,25,26)(H2,18,27,28)/t10-,15-/m0/s1
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n/an/an/a 230n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288859
PNG
(4-Methylsulfanyl-2-(2-{2-[2-(4-sulfamoyl-benzoylam...)
Show SMILES CSCC[C@@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C16H22N4O7S2/c1-28-7-6-12(16(24)25)20-14(22)9-18-13(21)8-19-15(23)10-2-4-11(5-3-10)29(17,26)27/h2-5,12H,6-9H2,1H3,(H,18,21)(H,19,23)(H,20,22)(H,24,25)(H2,17,26,27)/t12-/m1/s1
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n/an/an/a 160n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288860
PNG
(4-Carbamoyl-2-{2-[2-(4-sulfamoyl-benzoylamino)-ace...)
Show SMILES NC(=O)CC[C@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C16H21N5O8S/c17-12(22)6-5-11(16(26)27)21-14(24)8-19-13(23)7-20-15(25)9-1-3-10(4-2-9)30(18,28)29/h1-4,11H,5-8H2,(H2,17,22)(H,19,23)(H,20,25)(H,21,24)(H,26,27)(H2,18,28,29)/t11-/m0/s1
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n/an/an/a 270n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288861
PNG
(3,3-Dimethyl-2-{2-[2-(4-sulfamoyl-benzoylamino)-ac...)
Show SMILES CC(C)[C@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C16H22N4O7S/c1-9(2)14(16(24)25)20-13(22)8-18-12(21)7-19-15(23)10-3-5-11(6-4-10)28(17,26)27/h3-6,9,14H,7-8H2,1-2H3,(H,18,21)(H,19,23)(H,20,22)(H,24,25)(H2,17,26,27)/t14-/m0/s1
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n/an/an/a 260n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288862
PNG
(4-Methylsulfanyl-2-[2-(4-sulfamoyl-benzoylamino)-a...)
Show SMILES CSCCC(NC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C14H19N3O6S2/c1-24-7-6-11(14(20)21)17-12(18)8-16-13(19)9-2-4-10(5-3-9)25(15,22)23/h2-5,11H,6-8H2,1H3,(H,16,19)(H,17,18)(H,20,21)(H2,15,22,23)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288863
PNG
(3-Hydroxy-2-{2-[2-(4-sulfamoyl-benzoylamino)-acety...)
Show SMILES C[C@@H](O)[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C17H23N5O9S/c1-9(23)15(17(28)29)22-14(26)8-20-12(24)6-19-13(25)7-21-16(27)10-2-4-11(5-3-10)32(18,30)31/h2-5,9,15,23H,6-8H2,1H3,(H,19,25)(H,20,24)(H,21,27)(H,22,26)(H,28,29)(H2,18,30,31)/t9-,15+/m1/s1
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288864
PNG
(3-Phenyl-2-[2-(4-sulfamoyl-benzoylamino)-acetylami...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C18H19N3O6S/c19-28(26,27)14-8-6-13(7-9-14)17(23)20-11-16(22)21-15(18(24)25)10-12-4-2-1-3-5-12/h1-9,15H,10-11H2,(H,20,23)(H,21,22)(H,24,25)(H2,19,26,27)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288865
PNG
(2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]-penta...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(CCC(O)=O)C(O)=O
Show InChI InChI=1S/C14H17N3O8S/c15-26(24,25)9-3-1-8(2-4-9)13(21)16-7-11(18)17-10(14(22)23)5-6-12(19)20/h1-4,10H,5-7H2,(H,16,21)(H,17,18)(H,19,20)(H,22,23)(H2,15,24,25)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288866
PNG
(3-Naphthalen-2-yl-2-[2-(4-sulfamoyl-benzoylamino)-...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(Cc1ccc2ccccc2c1)C(O)=O
Show InChI InChI=1S/C22H21N3O6S/c23-32(30,31)18-9-7-16(8-10-18)21(27)24-13-20(26)25-19(22(28)29)12-14-5-6-15-3-1-2-4-17(15)11-14/h1-11,19H,12-13H2,(H,24,27)(H,25,26)(H,28,29)(H2,23,30,31)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288867
PNG
(2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]-succi...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(CC(O)=O)C(O)=O
Show InChI InChI=1S/C13H15N3O8S/c14-25(23,24)8-3-1-7(2-4-8)12(20)15-6-10(17)16-9(13(21)22)5-11(18)19/h1-4,9H,5-6H2,(H,15,20)(H,16,17)(H,18,19)(H,21,22)(H2,14,23,24)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288868
PNG
(5-Guanidino-2-(2-{2-[2-(4-sulfamoyl-benzoylamino)-...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C17H25N7O7S/c18-17(19)21-7-1-2-12(16(28)29)24-14(26)9-22-13(25)8-23-15(27)10-3-5-11(6-4-10)32(20,30)31/h3-6,12H,1-2,7-9H2,(H,22,25)(H,23,27)(H,24,26)(H,28,29)(H4,18,19,21)(H2,20,30,31)/t12-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288869
PNG
(2-(2-{2-[2-(4-Sulfamoyl-benzoylamino)-acetylamino]...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C18H23N5O10S/c19-34(32,33)11-3-1-10(2-4-11)17(29)22-8-14(25)20-7-13(24)21-9-15(26)23-12(18(30)31)5-6-16(27)28/h1-4,12H,5-9H2,(H,20,25)(H,21,24)(H,22,29)(H,23,26)(H,27,28)(H,30,31)(H2,19,32,33)/t12-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288871
PNG
(3-Methyl-2-{2-[2-(4-sulfamoyl-benzoylamino)-acetyl...)
Show SMILES CC(C)(C)[C@H](NC(=O)CNC(=O)CNC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O |r|
Show InChI InChI=1S/C17H24N4O7S/c1-17(2,3)14(16(25)26)21-13(23)9-19-12(22)8-20-15(24)10-4-6-11(7-5-10)29(18,27)28/h4-7,14H,8-9H2,1-3H3,(H,19,22)(H,20,24)(H,21,23)(H,25,26)(H2,18,27,28)/t14-/m1/s1
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n/an/an/a 240n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288872
PNG
(3-(4-Nitro-phenyl)-2-[2-(4-sulfamoyl-benzoylamino)...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCC(=O)NC(Cc1ccc(cc1)[N+]([O-])=O)C(O)=O
Show InChI InChI=1S/C18H18N4O8S/c19-31(29,30)14-7-3-12(4-8-14)17(24)20-10-16(23)21-15(18(25)26)9-11-1-5-13(6-2-11)22(27)28/h1-8,15H,9-10H2,(H,20,24)(H,21,23)(H,25,26)(H2,19,29,30)
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n/an/an/a 150n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50101337
PNG
((S)-4-Methyl-2-(4-sulfamoyl-benzoylamino)-pentanoi...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C13H18N2O5S/c1-8(2)7-11(13(17)18)15-12(16)9-3-5-10(6-4-9)21(14,19)20/h3-6,8,11H,7H2,1-2H3,(H,15,16)(H,17,18)(H2,14,19,20)/t11-/m0/s1
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50288873
PNG
(1-(4-Sulfamoyl-benzoyl)-pyrrolidine-2-carboxylic a...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)N1CCCC1C(O)=O
Show InChI InChI=1S/C12H14N2O5S/c13-20(18,19)9-5-3-8(4-6-9)11(15)14-7-1-2-10(14)12(16)17/h3-6,10H,1-2,7H2,(H,16,17)(H2,13,18,19)
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TBA

Curated by ChEMBL


Assay Description
Dissociation constant against human carbonic anhydrase II at 37 degree centigrade


Bioorg Med Chem Lett 6: 559-564 (1996)


Article DOI: 10.1016/0960-894X(96)00069-8
BindingDB Entry DOI: 10.7270/Q2V124SF
More data for this
Ligand-Target Pair
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