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Compile Data Set for Download or QSAR

Found 437 hits with Last Name = 'wrasidlo' and Initial = 'w'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50221566
PNG
(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5O2/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31)
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n/an/a 0.5n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97975
PNG
(US8481536, 565)
Show SMILES CN(CCN1CCCC1)C(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(Cl)ccc(O)c2F)cc1
Show InChI InChI=1S/C28H28ClFN6O2/c1-17-15-19(24-21(29)9-10-23(37)25(24)30)16-22-26(17)32-28(34-33-22)31-20-7-5-18(6-8-20)27(38)35(2)13-14-36-11-3-4-12-36/h5-10,15-16,37H,3-4,11-14H2,1-2H3,(H,31,32,34)
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n/an/a 0.542n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM97937
PNG
(US8481536, 507 | US8481536, 612)
Show SMILES Cc1cc2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2cc1-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5O2/c1-17-14-24-25(16-21(17)22-15-19(33)6-9-23(22)27)30-31-26(29-24)28-18-4-7-20(8-5-18)34-13-12-32-10-2-3-11-32/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31)
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n/an/a 0.700n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221549
PNG
(4-(7-(6-chloro-2-fluoro-3-hydroxyphenyl)-5-methylb...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1c(Cl)ccc(O)c1F
Show InChI InChI=1S/C26H26ClFN6O3S/c1-16-14-17(23-20(27)8-9-22(35)24(23)28)15-21-25(16)31-26(33-32-21)30-18-4-6-19(7-5-18)38(36,37)29-10-13-34-11-2-3-12-34/h4-9,14-15,29,35H,2-3,10-13H2,1H3,(H,30,31,33)
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n/an/a 0.700n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97969
PNG
(US8481536, 559)
Show SMILES Cc1ccc(O)cc1-c1cc(C)c2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2c1
Show InChI InChI=1S/C27H30N6O3S/c1-18-5-8-22(34)17-24(18)20-15-19(2)26-25(16-20)31-32-27(30-26)29-21-6-9-23(10-7-21)37(35,36)28-11-14-33-12-3-4-13-33/h5-10,15-17,28,34H,3-4,11-14H2,1-2H3,(H,29,30,32)
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n/an/a 0.955n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50193874
PNG
(7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidi...)
Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1
Show InChI InChI=1S/C28H31N5O/c1-19-7-6-8-20(2)26(19)22-17-21(3)27-25(18-22)31-32-28(30-27)29-23-9-11-24(12-10-23)34-16-15-33-13-4-5-14-33/h6-12,17-18H,4-5,13-16H2,1-3H3,(H,29,30,32)
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n/an/a 1n/an/an/an/an/an/a



TargeGen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Yes


Bioorg Med Chem Lett 16: 5546-50 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.035
BindingDB Entry DOI: 10.7270/Q2SN08MP
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97966
PNG
(US8481536, 555)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN3CCCC3)nc12)-c1c(Cl)ccc(O)c1F
Show InChI InChI=1S/C27H27ClFN5O3S/c1-17-15-18(24-21(28)9-10-23(35)25(24)29)16-22-26(17)31-27(33-32-22)30-19-5-7-20(8-6-19)38(36,37)14-4-13-34-11-2-3-12-34/h5-10,15-16,35H,2-4,11-14H2,1H3,(H,30,31,33)
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n/an/a 1n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221566
PNG
(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5O2/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31)
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n/an/a 1.10n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97965
PNG
(US8481536, 554)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1c(Cl)ccc(O)c1Cl
Show InChI InChI=1S/C26H25Cl2N5O2/c1-16-14-17(23-20(27)8-9-22(34)24(23)28)15-21-25(16)30-26(32-31-21)29-18-4-6-19(7-5-18)35-13-12-33-10-2-3-11-33/h4-9,14-15,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 1.10n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97942
PNG
(US8481536, 514)
Show SMILES Oc1ccc(Cl)c(c1)-c1cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc2cc1Cl
Show InChI InChI=1S/C25H23Cl2N5O2/c26-21-8-5-17(33)13-19(21)20-14-24-23(15-22(20)27)29-25(31-30-24)28-16-3-6-18(7-4-16)34-12-11-32-9-1-2-10-32/h3-8,13-15,33H,1-2,9-12H2,(H,28,29,31)
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n/an/a 1.20n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221563
PNG
((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C25H23ClN6O2/c1-15-12-17(20-14-19(33)6-7-21(20)26)13-22-23(15)29-25(31-30-22)28-18-4-2-16(3-5-18)24(34)32-10-8-27-9-11-32/h2-7,12-14,27,33H,8-11H2,1H3,(H,28,29,31)
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n/an/a 1.20n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM97982
PNG
(US8481536, 574)
Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCC4CCCC4)cc3)nnc2c1
Show InChI InChI=1S/C29H32N4O/c1-19-7-6-8-20(2)27(19)23-17-21(3)28-26(18-23)32-33-29(31-28)30-24-11-13-25(14-12-24)34-16-15-22-9-4-5-10-22/h6-8,11-14,17-18,22H,4-5,9-10,15-16H2,1-3H3,(H,30,31,33)
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n/an/a 1.20n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97974
PNG
(US8481536, 564)
Show SMILES CN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(Cl)ccc(O)c2F)cc1
Show InChI InChI=1S/C27H28ClFN6O3S/c1-17-15-18(24-21(28)9-10-23(36)25(24)29)16-22-26(17)31-27(33-32-22)30-19-5-7-20(8-6-19)39(37,38)34(2)13-14-35-11-3-4-12-35/h5-10,15-16,36H,3-4,11-14H2,1-2H3,(H,30,31,33)
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n/an/a 1.20n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM97907
PNG
(US8481536, 471 | US8481536, 606)
Show SMILES CN(C)CCNC(=O)c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)c1
Show InChI InChI=1S/C25H25ClN6O2/c1-15-11-17(20-14-19(33)7-8-21(20)26)13-22-23(15)29-25(31-30-22)28-18-6-4-5-16(12-18)24(34)27-9-10-32(2)3/h4-8,11-14,33H,9-10H2,1-3H3,(H,27,34)(H,28,29,31)
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n/an/a 1.24n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50221553
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H27ClN6O3S/c1-17-14-18(22-16-20(34)6-9-23(22)27)15-24-25(17)30-26(32-31-24)29-19-4-7-21(8-5-19)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 1.28n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97959
PNG
(US8481536, 546)
Show SMILES CC(C)N(CCO)Cc1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C26H28ClN5O2/c1-16(2)32(10-11-33)15-18-4-6-20(7-5-18)28-26-29-25-17(3)12-19(13-24(25)30-31-26)22-14-21(34)8-9-23(22)27/h4-9,12-14,16,33-34H,10-11,15H2,1-3H3,(H,28,29,31)
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n/an/a 1.5n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221546
PNG
(4-(7-(2,6-dichloro-3-hydroxyphenyl)-5-methylbenzo[...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1c(Cl)ccc(O)c1Cl
Show InChI InChI=1S/C26H26Cl2N6O3S/c1-16-14-17(23-20(27)8-9-22(35)24(23)28)15-21-25(16)31-26(33-32-21)30-18-4-6-19(7-5-18)38(36,37)29-10-13-34-11-2-3-12-34/h4-9,14-15,29,35H,2-3,10-13H2,1H3,(H,30,31,33)
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n/an/a 1.5n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221566
PNG
(4-chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)etho...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5O2/c1-17-14-18(22-16-20(33)6-9-23(22)27)15-24-25(17)29-26(31-30-24)28-19-4-7-21(8-5-19)34-13-12-32-10-2-3-11-32/h4-9,14-16,33H,2-3,10-13H2,1H3,(H,28,29,31)
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n/an/a 1.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97926
PNG
(US8481536, 493 | US8481536, 609)
Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H27ClN6O3S/c1-17-14-24-25(16-21(17)22-15-19(34)6-9-23(22)27)31-32-26(30-24)29-18-4-7-20(8-5-18)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 1.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97964
PNG
(US8481536, 553)
Show SMILES CN(CCN1CCCC1)C(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C28H29ClN6O2/c1-18-15-20(23-17-22(36)9-10-24(23)29)16-25-26(18)31-28(33-32-25)30-21-7-5-19(6-8-21)27(37)34(2)13-14-35-11-3-4-12-35/h5-10,15-17,36H,3-4,11-14H2,1-2H3,(H,30,31,33)
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n/an/a 1.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221553
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H27ClN6O3S/c1-17-14-18(22-16-20(34)6-9-23(22)27)15-24-25(17)30-26(32-31-24)29-19-4-7-21(8-5-19)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 1.70n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97930
PNG
(US8481536, 497)
Show SMILES Cc1cc(cc2nnc(Nc3cccc(OCCN4CCCC4)c3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5O2/c1-17-13-18(22-16-20(33)7-8-23(22)27)14-24-25(17)29-26(31-30-24)28-19-5-4-6-21(15-19)34-12-11-32-9-2-3-10-32/h4-8,13-16,33H,2-3,9-12H2,1H3,(H,28,29,31)
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n/an/a 1.80n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97940
PNG
(US8481536, 510)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(nc3)N3CCN(CCO)CC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C25H26ClN7O2/c1-16-12-17(20-14-19(35)3-4-21(20)26)13-22-24(16)29-25(31-30-22)28-18-2-5-23(27-15-18)33-8-6-32(7-9-33)10-11-34/h2-5,12-15,34-35H,6-11H2,1H3,(H,28,29,31)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM97926
PNG
(US8481536, 493 | US8481536, 609)
Show SMILES Cc1cc2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2cc1-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H27ClN6O3S/c1-17-14-24-25(16-21(17)22-15-19(34)6-9-23(22)27)31-32-26(30-24)29-18-4-7-20(8-5-18)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 1.90n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM97929
PNG
(US8481536, 496 | US8481536, 610)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(nc3)N3CCOCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C23H21ClN6O2/c1-14-10-15(18-12-17(31)3-4-19(18)24)11-20-22(14)27-23(29-28-20)26-16-2-5-21(25-13-16)30-6-8-32-9-7-30/h2-5,10-13,31H,6-9H2,1H3,(H,26,27,29)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97972
PNG
(US8481536, 562)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN3CCCC3)nc12)-c1c(Cl)ccc(O)c1Cl
Show InChI InChI=1S/C27H27Cl2N5O3S/c1-17-15-18(24-21(28)9-10-23(35)25(24)29)16-22-26(17)31-27(33-32-22)30-19-5-7-20(8-6-19)38(36,37)14-4-13-34-11-2-3-12-34/h5-10,15-16,35H,2-4,11-14H2,1H3,(H,30,31,33)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97967
PNG
(US8481536, 557)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)C3CCNCC3)nc12)-c1c(Cl)ccc(O)c1Cl
Show InChI InChI=1S/C25H23Cl2N5O3S/c1-14-12-15(22-19(26)6-7-21(33)23(22)27)13-20-24(14)30-25(32-31-20)29-16-2-4-17(5-3-16)36(34,35)18-8-10-28-11-9-18/h2-7,12-13,18,28,33H,8-11H2,1H3,(H,29,30,32)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM97983
PNG
(US8481536, 578)
Show SMILES CCN(CC)COc1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1
Show InChI InChI=1S/C27H31N5O/c1-6-32(7-2)17-33-23-13-9-12-22(16-23)28-27-29-26-20(5)14-21(15-24(26)30-31-27)25-18(3)10-8-11-19(25)4/h8-16H,6-7,17H2,1-5H3,(H,28,29,31)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97938
PNG
(US8481536, 508)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(nc3)C(=O)NCCN3CCCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN7O2/c1-16-12-17(20-14-19(35)5-6-21(20)27)13-23-24(16)31-26(33-32-23)30-18-4-7-22(29-15-18)25(36)28-8-11-34-9-2-3-10-34/h4-7,12-15,35H,2-3,8-11H2,1H3,(H,28,36)(H,30,31,33)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221556
PNG
(4-chloro-3-(5-methyl-3-(4-(piperidin-4-ylsulfonyl)...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)C3CCNCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C25H24ClN5O3S/c1-15-12-16(21-14-18(32)4-7-22(21)26)13-23-24(15)29-25(31-30-23)28-17-2-5-19(6-3-17)35(33,34)20-8-10-27-11-9-20/h2-7,12-14,20,27,32H,8-11H2,1H3,(H,28,29,31)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221555
PNG
(4-chloro-3-(5-methyl-3-(4-(3-(pyrrolidin-1-yl)prop...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN3CCCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C27H28ClN5O3S/c1-18-15-19(23-17-21(34)7-10-24(23)28)16-25-26(18)30-27(32-31-25)29-20-5-8-22(9-6-20)37(35,36)14-4-13-33-11-2-3-12-33/h5-10,15-17,34H,2-4,11-14H2,1H3,(H,29,30,32)
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n/an/a 2.90n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221557
PNG
((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C26H25ClN6O2/c1-16-13-18(21-15-20(34)7-8-22(21)27)14-23-24(16)29-26(31-30-23)28-19-5-3-17(4-6-19)25(35)33-11-9-32(2)10-12-33/h3-8,13-15,34H,9-12H2,1-2H3,(H,28,29,31)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221559
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES CN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C27H29ClN6O3S/c1-18-15-19(23-17-21(35)7-10-24(23)28)16-25-26(18)30-27(32-31-25)29-20-5-8-22(9-6-20)38(36,37)33(2)13-14-34-11-3-4-12-34/h5-10,15-17,35H,3-4,11-14H2,1-2H3,(H,29,30,32)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221552
PNG
(CHEMBL249819 | US8481536, 545 | {4-[7-(2-chloro-5-...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)N3CCS(=O)(=O)CC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C25H22ClN5O4S/c1-15-12-17(20-14-19(32)6-7-21(20)26)13-22-23(15)28-25(30-29-22)27-18-4-2-16(3-5-18)24(33)31-8-10-36(34,35)11-9-31/h2-7,12-14,32H,8-11H2,1H3,(H,27,28,30)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221550
PNG
(4-(7-(2,6-difluoro-3-hydroxyphenyl)-5-methylbenzo[...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1c(F)ccc(O)c1F
Show InChI InChI=1S/C26H26F2N6O3S/c1-16-14-17(23-20(27)8-9-22(35)24(23)28)15-21-25(16)31-26(33-32-21)30-18-4-6-19(7-5-18)38(36,37)29-10-13-34-11-2-3-12-34/h4-9,14-15,29,35H,2-3,10-13H2,1H3,(H,30,31,33)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50198817
PNG
(4-(7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]t...)
Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nnc2c1
Show InChI InChI=1S/C28H32N6O2S/c1-19-7-6-8-20(2)26(19)22-17-21(3)27-25(18-22)32-33-28(31-27)30-23-9-11-24(12-10-23)37(35,36)29-13-16-34-14-4-5-15-34/h6-12,17-18,29H,4-5,13-16H2,1-3H3,(H,30,31,33)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50221559
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES CN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C27H29ClN6O3S/c1-18-15-19(23-17-21(35)7-10-24(23)28)16-25-26(18)30-27(32-31-25)29-20-5-8-22(9-6-20)38(36,37)33(2)13-14-34-11-3-4-12-34/h5-10,15-17,35H,3-4,11-14H2,1-2H3,(H,29,30,32)
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TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221565
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES CCN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C28H31ClN6O3S/c1-3-35(15-14-34-12-4-5-13-34)39(37,38)23-9-6-21(7-10-23)30-28-31-27-19(2)16-20(17-26(27)32-33-28)24-18-22(36)8-11-25(24)29/h6-11,16-18,36H,3-5,12-15H2,1-2H3,(H,30,31,33)
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n/an/a 3.20n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97935
PNG
(US8481536, 502)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(nc3)N3CCNCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C23H22ClN7O/c1-14-10-15(18-12-17(32)3-4-19(18)24)11-20-22(14)28-23(30-29-20)27-16-2-5-21(26-13-16)31-8-6-25-7-9-31/h2-5,10-13,25,32H,6-9H2,1H3,(H,27,28,30)
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n/an/a 3.30n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97956
PNG
(US8481536, 542)
Show SMILES Cc1cc(cc2nnc(Nc3cccc(SCCN4CCCC4)c3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H26ClN5OS/c1-17-13-18(22-16-20(33)7-8-23(22)27)14-24-25(17)29-26(31-30-24)28-19-5-4-6-21(15-19)34-12-11-32-9-2-3-10-32/h4-8,13-16,33H,2-3,9-12H2,1H3,(H,28,29,31)
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n/an/a 3.40n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97889
PNG
(US8481536, 448 | US8481536, 596)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2nnc3cc(c(C)cc3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C26H25ClN6O2/c1-16-13-23-24(15-20(16)21-14-19(34)7-8-22(21)27)30-31-26(29-23)28-18-5-3-17(4-6-18)25(35)33-11-9-32(2)10-12-33/h3-8,13-15,34H,9-12H2,1-2H3,(H,28,29,31)
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n/an/a 3.40n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM97881
PNG
(US8481536, 438 | US8481536, 593)
Show SMILES COc1ccc(Cl)c(c1)-c1cc2nnc(Nc3ccc(cc3)C(=O)N3CCN(C)CC3)nc2cc1C
Show InChI InChI=1S/C27H27ClN6O2/c1-17-14-24-25(16-21(17)22-15-20(36-3)8-9-23(22)28)31-32-27(30-24)29-19-6-4-18(5-7-19)26(35)34-12-10-33(2)11-13-34/h4-9,14-16H,10-13H2,1-3H3,(H,29,30,32)
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n/an/a 3.5n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221563
PNG
((4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)C(=O)N3CCNCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C25H23ClN6O2/c1-15-12-17(20-14-19(33)6-7-21(20)26)13-22-23(15)29-25(31-30-22)28-18-4-2-16(3-5-18)24(34)32-10-8-27-9-11-32/h2-7,12-14,27,33H,8-11H2,1H3,(H,28,29,31)
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n/an/a 3.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221553
PNG
(4-(7-(2-chloro-5-hydroxyphenyl)-5-methylbenzo[e][1...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1cc(O)ccc1Cl
Show InChI InChI=1S/C26H27ClN6O3S/c1-17-14-18(22-16-20(34)6-9-23(22)27)15-24-25(17)30-26(32-31-24)29-19-4-7-21(8-5-19)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 3.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97981
PNG
(US8481536, 571)
Show SMILES CN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(cc(C)c3n2)-c2c(Cl)ccc(O)c2Cl)cc1
Show InChI InChI=1S/C27H28Cl2N6O3S/c1-17-15-18(24-21(28)9-10-23(36)25(24)29)16-22-26(17)31-27(33-32-22)30-19-5-7-20(8-6-19)39(37,38)34(2)13-14-35-11-3-4-12-35/h5-10,15-16,36H,3-4,11-14H2,1-2H3,(H,30,31,33)
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n/an/a 3.60n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM97889
PNG
(US8481536, 448 | US8481536, 596)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2nnc3cc(c(C)cc3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C26H25ClN6O2/c1-16-13-23-24(15-20(16)21-14-19(34)7-8-22(21)27)30-31-26(29-23)28-18-5-3-17(4-6-18)25(35)33-11-9-32(2)10-12-33/h3-8,13-15,34H,9-12H2,1-2H3,(H,28,29,31)
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n/an/a 3.70n/an/an/an/an/an/a



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Yes


(Homo sapiens (Human))
BDBM50193891
PNG
(7-(2,6-dimethylphenyl)-5-methyl-N-(3-(2-(pyrrolidi...)
Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(OCCN4CCCC4)c3)nnc2c1
Show InChI InChI=1S/C28H31N5O/c1-19-8-6-9-20(2)26(19)22-16-21(3)27-25(17-22)31-32-28(30-27)29-23-10-7-11-24(18-23)34-15-14-33-12-4-5-13-33/h6-11,16-18H,4-5,12-15H2,1-3H3,(H,29,30,32)
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n/an/a 3.70n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97963
PNG
(US8481536, 552)
Show SMILES CN(CCN1CCCC1)S(=O)(=O)c1ccc(Nc2nnc3cc(c(C)cc3n2)-c2cc(O)ccc2Cl)cc1
Show InChI InChI=1S/C27H29ClN6O3S/c1-18-15-25-26(17-22(18)23-16-20(35)7-10-24(23)28)31-32-27(30-25)29-19-5-8-21(9-6-19)38(36,37)33(2)13-14-34-11-3-4-12-34/h5-10,15-17,35H,3-4,11-14H2,1-2H3,(H,29,30,32)
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n/an/a 3.70n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM97973
PNG
(US8481536, 563)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)CCCN3CCCC3)nc12)-c1c(F)ccc(O)c1F
Show InChI InChI=1S/C27H27F2N5O3S/c1-17-15-18(24-21(28)9-10-23(35)25(24)29)16-22-26(17)31-27(33-32-22)30-19-5-7-20(8-6-19)38(36,37)14-4-13-34-11-2-3-12-34/h5-10,15-16,35H,2-4,11-14H2,1H3,(H,30,31,33)
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n/an/a 3.80n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50221562
PNG
(4-(7-(2-bromo-5-hydroxyphenyl)-5-methylbenzo[e][1,...)
Show SMILES Cc1cc(cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc12)-c1cc(O)ccc1Br
Show InChI InChI=1S/C26H27BrN6O3S/c1-17-14-18(22-16-20(34)6-9-23(22)27)15-24-25(17)30-26(32-31-24)29-19-4-7-21(8-5-19)37(35,36)28-10-13-33-11-2-3-12-33/h4-9,14-16,28,34H,2-3,10-13H2,1H3,(H,29,30,32)
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n/an/a 4.10n/an/an/an/an/a25



TargeGen, Inc.

US Patent


Assay Description
Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.


US Patent US8481536 (2013)


BindingDB Entry DOI: 10.7270/Q2GB22PZ
More data for this
Ligand-Target Pair
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