Compile Data Set for Download or QSAR

Found 433 hits with Last Name = 'wu' and Initial = 'mh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM21973 (1-Methyltryptophan, 1 | 2-amino-3-(1-methyl-1H-ind...) Show SMILES Cn1cc(CC(N)C(O)=O)c2ccccc12 Show InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human recombinant IDO using L-tryptophan as substrate				Bioorg Med Chem Lett 24: 3403-6 (2014) Article DOI: 10.1016/j.bmcl.2014.05.084 BindingDB Entry DOI: 10.7270/Q23R0VH6
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134505 (US8846656, 21-D) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1C |r| Show InChI InChI=1/C32H42N4O/c1-20(2)25-12-11-21(3)29(18-25)35-15-14-28-27(19-35)32(36-16-13-26(37-7)17-24(36)6)34-31(33-28)30-22(4)9-8-10-23(30)5/h8-12,18,20,24,26H,13-17,19H2,1-7H3/t24-,26-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134531 (US8846656, 23-I) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H40N8O/c1-18-7-10-23-28(19(2)34-35-23)27(18)29-32-22-11-13-38(26-15-24(20-8-9-20)36-37(26)5)16-21(22)30(33-29)39-14-12-25(40-6)31(3,4)17-39/h7,10,15,20,25H,8-9,11-14,16-17H2,1-6H3,(H,34,35)/t25-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134569 (US8846656, 52-C) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CCN(CC(N)=O)C[C@H]3C)c2C1)-c1cccc2[nH]cc(C)c12 |r| Show InChI InChI=1/C33H41N7O/c1-20(2)24-10-9-21(3)29(15-24)39-12-11-27-26(18-39)33(40-14-13-38(17-23(40)5)19-30(34)41)37-32(36-27)25-7-6-8-28-31(25)22(4)16-35-28/h6-10,15-16,20,23,35H,11-14,17-19H2,1-5H3,(H2,34,41)/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134577 (US8846656, 55-M) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C30H37ClN8O/c1-16-6-9-23-25(18(3)34-35-23)24(16)28-32-22-11-12-38(30-26(31)27(19-7-8-19)36-37(30)4)15-21(22)29(33-28)39-13-10-20(40-5)14-17(39)2/h6,9,17,19-20H,7-8,10-15H2,1-5H3,(H,34,35)/t17-,20-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134589 (US8846656, 65-I) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CCC3C)c2C1)-c1c(C)ccc2[nH]nc(C)c12 Show InChI InChI=1/C30H36N6/c1-17(2)22-9-7-18(3)26(15-22)35-13-12-24-23(16-35)30(36-14-11-20(36)5)32-29(31-24)27-19(4)8-10-25-28(27)21(6)33-34-25/h7-10,15,17,20H,11-14,16H2,1-6H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134596 (US8846656, 69-L) Show SMILES Cc1n[nH]c2ccc(C)c(-c3nc4CCN(Cc4c(n3)N3CC[C@@H]4OC[C@]4(C)C3)c3c(Cl)c(nn3C)C3CC3)c12 |r| Show InChI InChI=1/C30H35ClN8O/c1-16-5-8-21-24(17(2)34-35-21)23(16)27-32-20-9-11-38(29-25(31)26(18-6-7-18)36-37(29)4)13-19(20)28(33-27)39-12-10-22-30(3,14-39)15-40-22/h5,8,18,22H,6-7,9-15H2,1-4H3,(H,34,35)/t22-,30-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134586 (US8846656, 65-A) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CC(C3)N(C)C)c2C1)-c1c(C)ccc2[nH]nc(C)c12 Show InChI InChI=1S/C31H39N7/c1-18(2)22-10-8-19(3)27(14-22)37-13-12-25-24(17-37)31(38-15-23(16-38)36(6)7)33-30(32-25)28-20(4)9-11-26-29(28)21(5)34-35-26/h8-11,14,18,23H,12-13,15-17H2,1-7H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134518 (US8846656, 21-AG) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(Cl)ccc1C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C30H35ClN6O/c1-17-6-8-21(31)15-26(17)36-12-11-24-23(16-36)30(37-13-10-22(38-5)14-19(37)3)33-29(32-24)27-18(2)7-9-25-28(27)20(4)34-35-25/h6-9,15,19,22H,10-14,16H2,1-5H3,(H,34,35)/t19-,22-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134574 (US8846656, 55-I) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C(F)F)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C29H35ClF2N8O/c1-15-7-8-19-22(16(2)35-36-19)21(15)26-33-18-9-11-39(28-23(30)24(25(31)32)37-38(28)5)13-17(18)27(34-26)40-12-10-20(41-6)29(3,4)14-40/h7-8,20,25H,9-14H2,1-6H3,(H,35,36)/t20-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134519 (US8846656, 21-AH) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(F)(F)F)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H35F3N6O/c1-17-6-8-21(31(32,33)34)15-26(17)39-12-11-24-23(16-39)30(40-13-10-22(41-5)14-19(40)3)36-29(35-24)27-18(2)7-9-25-28(27)20(4)37-38-25/h6-9,15,19,22H,10-14,16H2,1-5H3,(H,37,38)/t19-,22-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134511 (US8846656, 21-Q) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C33H42N6O/c1-19(2)24-10-8-20(3)29(17-24)38-14-13-27-26(18-38)33(39-15-12-25(40-7)16-22(39)5)35-32(34-27)30-21(4)9-11-28-31(30)23(6)36-37-28/h8-11,17,19,22,25H,12-16,18H2,1-7H3,(H,36,37)/t22-,25-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134523 (US8846656, 21-AL) Show SMILES CCO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C34H44N6O/c1-8-41-26-13-16-40(23(6)17-26)34-27-19-39(30-18-25(20(2)3)11-9-21(30)4)15-14-28(27)35-33(36-34)31-22(5)10-12-29-32(31)24(7)37-38-29/h9-12,18,20,23,26H,8,13-17,19H2,1-7H3,(H,37,38)/t23-,26-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134524 (US8846656, 21-AM) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CCCC[C@H]3C)c2C1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C32H40N6/c1-19(2)24-12-10-20(3)28(17-24)37-16-14-26-25(18-37)32(38-15-8-7-9-22(38)5)34-31(33-26)29-21(4)11-13-27-30(29)23(6)35-36-27/h10-13,17,19,22H,7-9,14-16,18H2,1-6H3,(H,35,36)/t22-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134582 (US8846656, 56-F) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(F)c(nn1C)C(F)F)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C29H35F3N8O/c1-15-7-8-19-22(16(2)35-36-19)21(15)26-33-18-9-11-39(28-23(30)24(25(31)32)37-38(28)5)13-17(18)27(34-26)40-12-10-20(41-6)29(3,4)14-40/h7-8,20,25H,9-14H2,1-6H3,(H,35,36)/t20-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134512 (US8846656, 21-R) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C1(C)COC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C34H42N6O2/c1-20-7-9-24(34(5)18-42-19-34)16-29(20)39-13-12-27-26(17-39)33(40-14-11-25(41-6)15-22(40)3)36-32(35-27)30-21(2)8-10-28-31(30)23(4)37-38-28/h7-10,16,22,25H,11-15,17-19H2,1-6H3,(H,37,38)/t22-,25-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134500 (US8846656, 19-AF) Show SMILES CO[C@@H]1CCN(C[C@H]1C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C33H42N6O/c1-19(2)24-10-8-20(3)28(16-24)38-14-12-26-25(18-38)33(39-15-13-29(40-7)22(5)17-39)35-32(34-26)30-21(4)9-11-27-31(30)23(6)36-37-27/h8-11,16,19,22,29H,12-15,17-18H2,1-7H3,(H,36,37)/t22-,29-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134530 (US8846656, 23-H) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C30H38N8O/c1-17-6-9-24-28(19(3)33-34-24)27(17)29-31-23-11-12-37(26-15-25(20-7-8-20)35-36(26)4)16-22(23)30(32-29)38-13-10-21(39-5)14-18(38)2/h6,9,15,18,20-21H,7-8,10-14,16H2,1-5H3,(H,33,34)/t18-,21-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134580 (US8846656, 56-C) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(F)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H39FN8O/c1-17-7-10-22-25(18(2)35-36-22)24(17)28-33-21-11-13-39(30-26(32)27(19-8-9-19)37-38(30)5)15-20(21)29(34-28)40-14-12-23(41-6)31(3,4)16-40/h7,10,19,23H,8-9,11-16H2,1-6H3,(H,35,36)/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134520 (US8846656, 21-AI) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C34H44N6O/c1-20(2)24-11-9-21(3)28(17-24)39-15-13-26-25(18-39)33(40-16-14-29(41-8)34(6,7)19-40)36-32(35-26)30-22(4)10-12-27-31(30)23(5)37-38-27/h9-12,17,20,29H,13-16,18-19H2,1-8H3,(H,37,38)/t29-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134546 (US8846656, 29) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CCN([C@H](C)C3)S(C)(=O)=O)c2C1)-c1cccc2[nH]cc(C)c12 |r| Show InChI InChI=1/C32H40N6O2S/c1-20(2)24-11-10-21(3)29(16-24)36-13-12-27-26(19-36)32(37-14-15-38(23(5)18-37)41(6,39)40)35-31(34-27)25-8-7-9-28-30(25)22(4)17-33-28/h7-11,16-17,20,23,33H,12-15,18-19H2,1-6H3/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134601 (US8846656, 71-B) Show SMILES CCn1nc(C2CC2)c(F)c1N1CCc2nc(nc(N3CC[C@@H](OC)C(C)(C)C3)c2C1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C32H41FN8O/c1-7-41-31(27(33)28(38-41)20-9-10-20)39-14-12-22-21(16-39)30(40-15-13-24(42-6)32(4,5)17-40)35-29(34-22)25-18(2)8-11-23-26(25)19(3)36-37-23/h8,11,20,24H,7,9-10,12-17H2,1-6H3,(H,36,37)/t24-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134590 (US8846656, 65-K) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CCOC[C@H]3C)c2C1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H38N6O/c1-18(2)23-9-7-19(3)27(15-23)36-12-11-25-24(16-36)31(37-13-14-38-17-21(37)5)33-30(32-25)28-20(4)8-10-26-29(28)22(6)34-35-26/h7-10,15,18,21H,11-14,16-17H2,1-6H3,(H,34,35)/t21-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134587 (US8846656, 65-B) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3CC[C@H](C3)N(C)C)c2C1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C32H41N7/c1-19(2)23-10-8-20(3)28(16-23)38-15-13-26-25(18-38)32(39-14-12-24(17-39)37(6)7)34-31(33-26)29-21(4)9-11-27-30(29)22(5)35-36-27/h8-11,16,19,24H,12-15,17-18H2,1-7H3,(H,35,36)/t24-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134591 (US8846656, 68-B) Show SMILES CCOC1CN(C1)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 Show InChI InChI=1S/C28H33ClN8O/c1-5-38-18-12-37(13-18)27-19-14-36(28-24(29)25(17-7-8-17)34-35(28)4)11-10-20(19)30-26(31-27)22-15(2)6-9-21-23(22)16(3)32-33-21/h6,9,17-18H,5,7-8,10-14H2,1-4H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134581 (US8846656, 56-E) Show SMILES CCO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(F)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C32H41FN8O/c1-7-42-24-13-15-41(17-32(24,4)5)30-21-16-40(31-27(33)28(20-9-10-20)38-39(31)6)14-12-22(21)34-29(35-30)25-18(2)8-11-23-26(25)19(3)36-37-23/h8,11,20,24H,7,9-10,12-17H2,1-6H3,(H,36,37)/t24-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134507 (US8846656, 21-K) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C1(C)COC1)-c1c(C)cccc1C |r| Show InChI InChI=1/C33H42N4O2/c1-21-10-11-25(33(5)19-39-20-33)17-29(21)36-14-13-28-27(18-36)32(37-15-12-26(38-6)16-24(37)4)35-31(34-28)30-22(2)8-7-9-23(30)3/h7-11,17,24,26H,12-16,18-20H2,1-6H3/t24-,26-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134509 (US8846656, 21-N) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(OC)ccc1C)-c1c(C)cccc1C |r| Show InChI InChI=1/C30H38N4O2/c1-19-10-11-23(35-5)17-27(19)33-14-13-26-25(18-33)30(34-15-12-24(36-6)16-22(34)4)32-29(31-26)28-20(2)8-7-9-21(28)3/h7-11,17,22,24H,12-16,18H2,1-6H3/t22-,24-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134579 (US8846656, 56-B) Show SMILES CO[C@@H]1C[C@@H]2CC[C@H](C1)N2c1nc(nc2CCN(Cc12)c1c(F)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r,THB:10:9:3.2.8:6.5| Show InChI InChI=1/C31H37FN8O/c1-16-5-10-24-26(17(2)35-36-24)25(16)29-33-23-11-12-39(31-27(32)28(18-6-7-18)37-38(31)3)15-22(23)30(34-29)40-19-8-9-20(40)14-21(13-19)41-4/h5,10,18-21H,6-9,11-15H2,1-4H3,(H,35,36)/t19-,20+,21+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134572 (US8846656, 55-G) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H39ClN8O/c1-17-7-10-22-25(18(2)35-36-22)24(17)28-33-21-11-13-39(30-26(32)27(19-8-9-19)37-38(30)5)15-20(21)29(34-28)40-14-12-23(41-6)31(3,4)16-40/h7,10,19,23H,8-9,11-16H2,1-6H3,(H,35,36)/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134551 (US8846656, 32-B) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(Cl)c12 |r| Show InChI InChI=1/C33H41ClN6O/c1-19(2)22-10-8-20(3)26(16-22)39-14-12-24-23(17-39)32(40-15-13-27(41-7)33(5,6)18-40)36-31(35-24)28-21(4)9-11-25-29(28)30(34)38-37-25/h8-11,16,19,27H,12-15,17-18H2,1-7H3,(H,37,38)/t27-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134502 (US8846656, 19-AI) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C34H44N6O/c1-20(2)24-11-9-21(3)28(17-24)39-15-13-26-25(18-39)33(40-16-14-29(41-8)34(6,7)19-40)36-32(35-26)30-22(4)10-12-27-31(30)23(5)37-38-27/h9-12,17,20,29H,13-16,18-19H2,1-8H3,(H,37,38)/t29-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134498 (US8846656, 19-AD) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1C |r| Show InChI InChI=1/C33H44N4O/c1-21(2)25-13-12-22(3)28(18-25)36-16-14-27-26(19-36)32(37-17-15-29(38-8)33(6,7)20-37)35-31(34-27)30-23(4)10-9-11-24(30)5/h9-13,18,21,29H,14-17,19-20H2,1-8H3/t29-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134529 (US8846656, 23-G) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(nn1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C30H40N8O/c1-17(2)25-15-26(36(6)35-25)37-12-11-23-22(16-37)30(38-13-10-21(39-7)14-19(38)4)32-29(31-23)27-18(3)8-9-24-28(27)20(5)33-34-24/h8-9,15,17,19,21H,10-14,16H2,1-7H3,(H,33,34)/t19-,21-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134479 (US8846656, 17-AM) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1cccc2[nH]cc(C)c12 |r| Show InChI InChI=1/C34H43N5O/c1-21(2)24-12-11-22(3)29(17-24)38-15-13-27-26(19-38)33(39-16-14-30(40-7)34(5,6)20-39)37-32(36-27)25-9-8-10-28-31(25)23(4)18-35-28/h8-12,17-18,21,30,35H,13-16,19-20H2,1-7H3/t30-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134571 (US8846656, 54-B) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C30H39ClN8O/c1-16(2)27-26(31)30(37(6)36-27)38-12-11-22-21(15-38)29(39-13-10-20(40-7)14-18(39)4)33-28(32-22)24-17(3)8-9-23-25(24)19(5)34-35-23/h8-9,16,18,20H,10-15H2,1-7H3,(H,34,35)/t18-,20-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134525 (US8846656, 22-C) Show SMILES CO[C@@H]1CCN([C@H](C)C1)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(cnc2[nH]ccc12)C(F)(F)F |r| Show InChI InChI=1/C32H37F3N6O/c1-18(2)21-7-6-19(3)27(15-21)40-12-10-26-24(17-40)31(41-13-9-22(42-5)14-20(41)4)39-30(38-26)28-23-8-11-36-29(23)37-16-25(28)32(33,34)35/h6-8,11,15-16,18,20,22H,9-10,12-14,17H2,1-5H3,(H,36,37)/t20-,22-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134576 (US8846656, 55-L) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H39ClN8O/c1-17-7-10-22-25(18(2)35-36-22)24(17)28-33-21-11-13-39(30-26(32)27(19-8-9-19)37-38(30)5)15-20(21)29(34-28)40-14-12-23(41-6)31(3,4)16-40/h7,10,19,23H,8-9,11-16H2,1-6H3,(H,35,36)/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134544 (US8846656, 28-B) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3C[C@H](C)N(CC(N)=O)C[C@H]3C)c2C1)-c1c(C)cccc1C |r| Show InChI InChI=1/C33H44N6O/c1-20(2)26-12-11-21(3)29(15-26)37-14-13-28-27(18-37)33(36-32(35-28)31-22(4)9-8-10-23(31)5)39-17-24(6)38(16-25(39)7)19-30(34)40/h8-12,15,20,24-25H,13-14,16-19H2,1-7H3,(H2,34,40)/t24-,25+/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134562 (US8846656, 41-G) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(cc(C)c2C1)-c1c(ccc2[nH]ncc12)C(C)C Show InChI InChI=1S/C29H34N4/c1-17(2)21-8-7-19(5)28(14-21)33-12-11-25-24(16-33)20(6)13-27(31-25)29-22(18(3)4)9-10-26-23(29)15-30-32-26/h7-10,13-15,17-18H,11-12,16H2,1-6H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134517 (US8846656, 21-AF) Show SMILES CO[C@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1ccc(F)c2[nH]cc(C)c12 |r| Show InChI InChI=1/C34H42FN5O/c1-20(2)23-9-8-21(3)28(16-23)39-14-12-27-25(18-39)33(40-15-13-29(41-7)34(5,6)19-40)38-32(37-27)24-10-11-26(35)31-30(24)22(4)17-36-31/h8-11,16-17,20,29,36H,12-15,18-19H2,1-7H3/t29-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134490 (US8846656, 19-F) Show SMILES CO[C@@H]1C[C@@H]2CC[C@H](C1)N2c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r,THB:10:9:3.2.8:6.5| Show InChI InChI=1/C34H42N6O/c1-19(2)23-9-7-20(3)30(15-23)39-14-13-28-27(18-39)34(40-24-10-11-25(40)17-26(16-24)41-6)36-33(35-28)31-21(4)8-12-29-32(31)22(5)37-38-29/h7-9,12,15,19,24-26H,10-11,13-14,16-18H2,1-6H3,(H,37,38)/t24-,25+,26+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134594 (US8846656, 69-I) Show SMILES CO[C@@H]1CN([C@H]1C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C28H33ClN8O/c1-14-6-9-20-23(15(2)32-33-20)22(14)26-30-19-10-11-36(28-24(29)25(17-7-8-17)34-35(28)4)12-18(19)27(31-26)37-13-21(38-5)16(37)3/h6,9,16-17,21H,7-8,10-13H2,1-5H3,(H,32,33)/t16-,21+/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134588 (US8846656, 65-H) Show SMILES COC1CN(C[C@@H]1N(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C33H43N7O/c1-19(2)23-11-9-20(3)27(15-23)39-14-13-25-24(16-39)33(40-17-28(38(6)7)29(18-40)41-8)35-32(34-25)30-21(4)10-12-26-31(30)22(5)36-37-26/h9-12,15,19,28-29H,13-14,16-18H2,1-8H3,(H,36,37)/t28-,29?/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134593 (US8846656, 69-H) Show SMILES C[C@H]1[C@H](O)CN1c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C27H31ClN8O/c1-13-5-8-19-22(14(2)31-32-19)21(13)25-29-18-9-10-35(27-23(28)24(16-6-7-16)33-34(27)4)11-17(18)26(30-25)36-12-20(37)15(36)3/h5,8,15-16,20,37H,6-7,9-12H2,1-4H3,(H,31,32)/t15-,20+/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134572 (US8846656, 55-G) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C31H39ClN8O/c1-17-7-10-22-25(18(2)35-36-22)24(17)28-33-21-11-13-39(30-26(32)27(19-8-9-19)37-38(30)5)15-20(21)29(34-28)40-14-12-23(41-6)31(3,4)16-40/h7,10,19,23H,8-9,11-16H2,1-6H3,(H,35,36)/t23-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134573 (US8846656, 55-H) Show SMILES CCO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1c(Cl)c(nn1C)C1CC1)-c1c(C)ccc2[nH]nc(C)c12 |r| Show InChI InChI=1/C32H41ClN8O/c1-7-42-24-13-15-41(17-32(24,4)5)30-21-16-40(31-27(33)28(20-9-10-20)38-39(31)6)14-12-22(21)34-29(35-30)25-18(2)8-11-23-26(25)19(3)36-37-23/h8,11,20,24H,7,9-10,12-17H2,1-6H3,(H,36,37)/t24-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134515 (US8846656, 21-AB) Show SMILES CO[C@@H]1CCN(CC1(C)C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(F)(F)F)-c1c(C)cccc1C |r| Show InChI InChI=1/C31H37F3N4O/c1-19-10-11-22(31(32,33)34)16-25(19)37-14-12-24-23(17-37)29(38-15-13-26(39-6)30(4,5)18-38)36-28(35-24)27-20(2)8-7-9-21(27)3/h7-11,16,26H,12-15,17-18H2,1-6H3/t26-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134501 (US8846656, 19-AH) Show SMILES CO[C@@H]1CCN(C[C@H]1C)c1nc(nc2CCN(Cc12)c1cc(ccc1C)C(C)C)-c1c(C)cccc1Cl |r| Show InChI InChI=1/C31H39ClN4O/c1-19(2)23-11-10-20(3)27(16-23)35-14-12-26-24(18-35)31(36-15-13-28(37-6)22(5)17-36)34-30(33-26)29-21(4)8-7-9-25(29)32/h7-11,16,19,22,28H,12-15,17-18H2,1-6H3/t22-,28-/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human))	BDBM134545 (US8846656, 28-D) Show SMILES CC(C)c1ccc(C)c(c1)N1CCc2nc(nc(N3C[C@H](C)N(CC(N)=O)C[C@H]3C)c2C1)-c1cccc2[nH]cc(C)c12 |r| Show InChI InChI=1/C34H43N7O/c1-20(2)25-11-10-21(3)30(14-25)39-13-12-28-27(18-39)34(41-17-23(5)40(16-24(41)6)19-31(35)42)38-33(37-28)26-8-7-9-29-32(26)22(4)15-36-29/h7-11,14-15,20,23-24,36H,12-13,16-19H2,1-6H3,(H2,35,42)/t23-,24+/s2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...				US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR
					More data for this Ligand-Target Pair

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