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Compile Data Set for Download or QSAR

Found 177 hits with Last Name = 'zhong' and Initial = 'j'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent dopamine transporter


(Homo sapiens (Human))
BDBM50398789
PNG
(CHEMBL2180073)
Show SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 |r|
Show InChI InChI=1S/C21H25N5O3/c1-14(25-12-17(13-25)29-16-5-3-2-4-6-16)19-23-20-18(21(27)24-19)11-22-26(20)15-7-9-28-10-8-15/h2-6,11,14-15,17H,7-10,12-13H2,1H3,(H,23,24,27)/t14-/m1/s1
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293n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))
BDBM50398807
PNG
(CHEMBL2180074)
Show SMILES CC(N1CC(C1)Oc1ccc(F)cc1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C21H24FN5O3/c1-13(26-11-17(12-26)30-16-4-2-14(22)3-5-16)19-24-20-18(21(28)25-19)10-23-27(20)15-6-8-29-9-7-15/h2-5,10,13,15,17H,6-9,11-12H2,1H3,(H,24,25,28)
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1.20E+3n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))
BDBM50398804
PNG
(CHEMBL2177497)
Show SMILES CC(N1CC(C1)Oc1ccc(cc1)C#N)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C22H24N6O3/c1-14(27-12-18(13-27)31-17-4-2-15(10-23)3-5-17)20-25-21-19(22(29)26-20)11-24-28(21)16-6-8-30-9-7-16/h2-5,11,14,16,18H,6-9,12-13H2,1H3,(H,25,26,29)
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>1.00E+4n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Sodium-dependent dopamine transporter


(Homo sapiens (Human))
BDBM50398800
PNG
(CHEMBL2180069)
Show SMILES C[C@@H](N1CC(C1)Oc1ncccn1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 |r|
Show InChI InChI=1S/C19H23N7O3/c1-12(25-10-14(11-25)29-19-20-5-2-6-21-19)16-23-17-15(18(27)24-16)9-22-26(17)13-3-7-28-8-4-13/h2,5-6,9,12-14H,3-4,7-8,10-11H2,1H3,(H,23,24,27)/t12-/m1/s1
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>1.00E+4n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DAT


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398800
PNG
(CHEMBL2180069)
Show SMILES C[C@@H](N1CC(C1)Oc1ncccn1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 |r|
Show InChI InChI=1S/C19H23N7O3/c1-12(25-10-14(11-25)29-19-20-5-2-6-21-19)16-23-17-15(18(27)24-16)9-22-26(17)13-3-7-28-8-4-13/h2,5-6,9,12-14H,3-4,7-8,10-11H2,1H3,(H,23,24,27)/t12-/m1/s1
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n/an/a 7n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398790
PNG
(CHEMBL2180072)
Show SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C21H25N5O2/c1-14(25-12-17(13-25)28-16-9-3-2-4-10-16)19-23-20-18(21(27)24-19)11-22-26(20)15-7-5-6-8-15/h2-4,9-11,14-15,17H,5-8,12-13H2,1H3,(H,23,24,27)/t14-/m1/s1
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n/an/a 11n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398802
PNG
(CHEMBL2180066)
Show SMILES CC(N1CC(C1)Oc1ccc(C#N)c(Cl)c1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C22H23ClN6O3/c1-13(28-11-17(12-28)32-16-3-2-14(9-24)19(23)8-16)20-26-21-18(22(30)27-20)10-25-29(21)15-4-6-31-7-5-15/h2-3,8,10,13,15,17H,4-7,11-12H2,1H3,(H,26,27,30)
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n/an/a 19n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398789
PNG
(CHEMBL2180073)
Show SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 |r|
Show InChI InChI=1S/C21H25N5O3/c1-14(25-12-17(13-25)29-16-5-3-2-4-6-16)19-23-20-18(21(27)24-19)11-22-26(20)15-7-9-28-10-8-15/h2-6,11,14-15,17H,7-10,12-13H2,1H3,(H,23,24,27)/t14-/m1/s1
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n/an/a 22n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444153
PNG
(CHEMBL3093304)
Show SMILES OC(=O)c1cc(ccc1N1CCC(Cc2ccc(F)cc2)C1)C(F)(F)F
Show InChI InChI=1S/C19H17F4NO2/c20-15-4-1-12(2-5-15)9-13-7-8-24(11-13)17-6-3-14(19(21,22)23)10-16(17)18(25)26/h1-6,10,13H,7-9,11H2,(H,25,26)
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n/an/a 25n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398799
PNG
(CHEMBL2180070)
Show SMILES C[C@@H](N1CC(C1)c1ncccn1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C19H23N7O/c1-12(25-10-13(11-25)17-20-7-4-8-21-17)16-23-18-15(19(27)24-16)9-22-26(18)14-5-2-3-6-14/h4,7-9,12-14H,2-3,5-6,10-11H2,1H3,(H,23,24,27)/t12-/m1/s1
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n/an/a 32n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398803
PNG
(CHEMBL2180065)
Show SMILES CC(N1CC(C1)Oc1ccc(C#N)c(F)c1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C22H23FN6O3/c1-13(28-11-17(12-28)32-16-3-2-14(9-24)19(23)8-16)20-26-21-18(22(30)27-20)10-25-29(21)15-4-6-31-7-5-15/h2-3,8,10,13,15,17H,4-7,11-12H2,1H3,(H,26,27,30)
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n/an/a 43n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398790
PNG
(CHEMBL2180072)
Show SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C21H25N5O2/c1-14(25-12-17(13-25)28-16-9-3-2-4-10-16)19-23-20-18(21(27)24-19)11-22-26(20)15-7-5-6-8-15/h2-4,9-11,14-15,17H,5-8,12-13H2,1H3,(H,23,24,27)/t14-/m1/s1
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n/an/a 45n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398801
PNG
(CHEMBL2180067)
Show SMILES CC(N1CC(C1)Oc1ccc(F)c(c1)C#N)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C22H23FN6O3/c1-13(28-11-17(12-28)32-16-2-3-19(23)14(8-16)9-24)20-26-21-18(22(30)27-20)10-25-29(21)15-4-6-31-7-5-15/h2-3,8,10,13,15,17H,4-7,11-12H2,1H3,(H,26,27,30)
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n/an/a 47n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398807
PNG
(CHEMBL2180074)
Show SMILES CC(N1CC(C1)Oc1ccc(F)cc1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C21H24FN5O3/c1-13(26-11-17(12-26)30-16-4-2-14(22)3-5-16)19-24-20-18(21(28)25-19)10-23-27(20)15-6-8-29-9-7-15/h2-5,10,13,15,17H,6-9,11-12H2,1H3,(H,24,25,28)
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n/an/a 50n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398806
PNG
(CHEMBL2180075)
Show SMILES CC(N1CC(C1)Oc1cc(F)ccc1F)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C21H23F2N5O3/c1-12(27-10-15(11-27)31-18-8-13(22)2-3-17(18)23)19-25-20-16(21(29)26-19)9-24-28(20)14-4-6-30-7-5-14/h2-3,8-9,12,14-15H,4-7,10-11H2,1H3,(H,25,26,29)
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n/an/a 57n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361134
PNG
(CHEMBL1933609)
Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C15H12N4O3/c1-10-14(11-5-7-12(8-6-11)19(21)22)15(20)18(17-10)13-4-2-3-9-16-13/h2-9,17H,1H3
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n/an/a 60n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398800
PNG
(CHEMBL2180069)
Show SMILES C[C@@H](N1CC(C1)Oc1ncccn1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1 |r|
Show InChI InChI=1S/C19H23N7O3/c1-12(25-10-14(11-25)29-19-20-5-2-6-21-19)16-23-17-15(18(27)24-16)9-22-26(17)13-3-7-28-8-4-13/h2,5-6,9,12-14H,3-4,7-8,10-11H2,1H3,(H,23,24,27)/t12-/m1/s1
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n/an/a 63n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398805
PNG
(CHEMBL2177496)
Show SMILES CC(N1CC(C1)Oc1ccc(F)c(Cl)c1)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C21H23ClFN5O3/c1-12(27-10-15(11-27)31-14-2-3-18(23)17(22)8-14)19-25-20-16(21(29)26-19)9-24-28(20)13-4-6-30-7-5-13/h2-3,8-9,12-13,15H,4-7,10-11H2,1H3,(H,25,26,29)
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n/an/a 64n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398804
PNG
(CHEMBL2177497)
Show SMILES CC(N1CC(C1)Oc1ccc(cc1)C#N)c1nc2n(ncc2c(=O)[nH]1)C1CCOCC1
Show InChI InChI=1S/C22H24N6O3/c1-14(27-12-18(13-27)31-17-4-2-15(10-23)3-5-17)20-25-21-19(22(29)26-20)11-24-28(21)16-6-8-30-9-7-16/h2-5,11,14,16,18H,6-9,12-13H2,1H3,(H,25,26,29)
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n/an/a 70n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231517
PNG
(US9346818, I-2)
Show SMILES Fc1ccccc1CN1CCC(CCN2C(=O)c3cc4OCOc4cc3C2=O)CC1
Show InChI InChI=1S/C23H23FN2O4/c24-19-4-2-1-3-16(19)13-25-8-5-15(6-9-25)7-10-26-22(27)17-11-20-21(30-14-29-20)12-18(17)23(26)28/h1-4,11-12,15H,5-10,13-14H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231516
PNG
(US9346818, I-1)
Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)C(=O)c2cc3OCOc3cc12
Show InChI InChI=1S/C23H24N2O4/c26-22-18-12-20-21(29-15-28-20)13-19(18)23(27)25(22)11-8-16-6-9-24(10-7-16)14-17-4-2-1-3-5-17/h1-5,12-13,16H,6-11,14-15H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444147
PNG
(CHEMBL3093396)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCOCc1ccccc1)C(F)(F)F |r|
Show InChI InChI=1S/C21H22F3NO4/c22-21(23,24)16-6-7-19(18(12-16)20(26)27)25-9-8-17(13-25)29-11-10-28-14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,26,27)/t17-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM8960
PNG
((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Show SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
Show InChI InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
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n/an/a 94n/an/an/an/an/an/a



Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Endothelial lipase


(Homo sapiens (Human))
BDBM50444138
PNG
(CHEMBL3093392)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r|
Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Phosphodiesterase 1C (PDE1C)


(Homo sapiens (Human))
BDBM50398790
PNG
(CHEMBL2180072)
Show SMILES C[C@@H](N1CC(C1)Oc1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C21H25N5O2/c1-14(25-12-17(13-25)28-16-9-3-2-4-10-16)19-23-20-18(21(27)24-19)11-22-26(20)15-7-5-6-8-15/h2-4,9-11,14-15,17H,5-8,12-13H2,1H3,(H,23,24,27)/t14-/m1/s1
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n/an/a 116n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE1C


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444140
PNG
(CHEMBL3093394)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ncccc1F)C(F)(F)F |r|
Show InChI InChI=1S/C18H16F4N2O3/c19-14-2-1-6-23-15(14)10-27-12-5-7-24(9-12)16-4-3-11(18(20,21)22)8-13(16)17(25)26/h1-4,6,8,12H,5,7,9-10H2,(H,25,26)/t12-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444141
PNG
(CHEMBL3093393)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r|
Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human endothelial lipase using HDL as substrate assessed as release of free fatty acids preincubated for 30 mins followed by substrate ...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444150
PNG
(CHEMBL3093307)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cc1)C(F)(F)F |r|
Show InChI InChI=1S/C19H17F4NO3/c20-14-4-1-12(2-5-14)11-27-15-7-8-24(10-15)17-6-3-13(19(21,22)23)9-16(17)18(25)26/h1-6,9,15H,7-8,10-11H2,(H,25,26)/t15-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398791
PNG
(CHEMBL2177504)
Show SMILES COc1ccccc1OC1CCN(C1)[C@H](C)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C23H29N5O3/c1-15(27-12-11-17(14-27)31-20-10-6-5-9-19(20)30-2)21-25-22-18(23(29)26-21)13-24-28(22)16-7-3-4-8-16/h5-6,9-10,13,15-17H,3-4,7-8,11-12,14H2,1-2H3,(H,25,26,29)/t15-,17?/m1/s1
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Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361135
PNG
(CHEMBL1933610)
Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C16H12F3N3O/c1-10-14(11-5-7-12(8-6-11)16(17,18)19)15(23)22(21-10)13-4-2-3-9-20-13/h2-9,21H,1H3
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Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361105
PNG
(CHEMBL1933782)
Show SMILES Cc1ccc2nc(sc2c1)-n1[nH]c2CCc3ccccc3-c2c1=O
Show InChI InChI=1S/C19H15N3OS/c1-11-6-8-14-16(10-11)24-19(20-14)22-18(23)17-13-5-3-2-4-12(13)7-9-15(17)21-22/h2-6,8,10,21H,7,9H2,1H3
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Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231533
PNG
(US9346818, I-18)
Show SMILES Fc1ccccc1CN1CCC(CCN2C(=O)c3cc4OCOc4cc3C22CC2)CC1
Show InChI InChI=1S/C25H27FN2O3/c26-21-4-2-1-3-18(21)15-27-10-5-17(6-11-27)7-12-28-24(29)19-13-22-23(31-16-30-22)14-20(19)25(28)8-9-25/h1-4,13-14,17H,5-12,15-16H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444148
PNG
(CHEMBL3093309)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCC1CC1)C(F)(F)F |r|
Show InChI InChI=1S/C17H20F3NO3/c18-17(19,20)12-3-4-15(14(9-12)16(22)23)21-7-5-13(10-21)24-8-6-11-1-2-11/h3-4,9,11,13H,1-2,5-8,10H2,(H,22,23)/t13-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231551
PNG
(US9346818, I-36)
Show SMILES O=C1N(CCC2CCN(Cc3ccccn3)CC2)C(=O)c2cc3OCOc3cc12
Show InChI InChI=1S/C22H23N3O4/c26-21-17-11-19-20(29-14-28-19)12-18(17)22(27)25(21)10-6-15-4-8-24(9-5-15)13-16-3-1-2-7-23-16/h1-3,7,11-12,15H,4-6,8-10,13-14H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231519
PNG
(US9346818, I-4)
Show SMILES Fc1ccc(CN2CCC(CCN3C(=O)c4cc5OCOc5cc4C3=O)CC2)cc1
Show InChI InChI=1S/C23H23FN2O4/c24-17-3-1-16(2-4-17)13-25-8-5-15(6-9-25)7-10-26-22(27)18-11-20-21(30-14-29-20)12-19(18)23(26)28/h1-4,11-12,15H,5-10,13-14H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361122
PNG
(CHEMBL1933598)
Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H13F3N4O2/c1-10-14(16(26)24(23-10)13-7-2-3-8-21-13)15(25)22-12-6-4-5-11(9-12)17(18,19)20/h2-9,23H,1H3,(H,22,25)
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Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444144
PNG
(CHEMBL3093302)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r|
Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231532
PNG
(US9346818, I-17 | US9346818, I-34)
Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)C2(CC2)c2cc3OCOc3cc12
Show InChI InChI=1S/C25H28N2O3/c28-24-20-14-22-23(30-17-29-22)15-21(20)25(9-10-25)27(24)13-8-18-6-11-26(12-7-18)16-19-4-2-1-3-5-19/h1-5,14-15,18H,6-13,16-17H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361123
PNG
(CHEMBL1933599)
Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1C(=O)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C16H13N5O4/c1-10-14(16(23)20(19-10)13-4-2-3-9-17-13)15(22)18-11-5-7-12(8-6-11)21(24)25/h2-9,19H,1H3,(H,18,22)
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Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231532
PNG
(US9346818, I-17 | US9346818, I-34)
Show SMILES O=C1N(CCC2CCN(Cc3ccccc3)CC2)C2(CC2)c2cc3OCOc3cc12
Show InChI InChI=1S/C25H28N2O3/c28-24-20-14-22-23(30-17-29-22)15-21(20)25(9-10-25)27(24)13-8-18-6-11-26(12-7-18)16-19-4-2-1-3-5-19/h1-5,14-15,18H,6-13,16-17H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444158
PNG
(CHEMBL3093401)
Show SMILES Fc1ccc(O[C@H]2CCN(C2)c2ccc(cc2-c2nnn[nH]2)C(F)(F)F)cc1 |r|
Show InChI InChI=1S/C18H15F4N5O/c19-12-2-4-13(5-3-12)28-14-7-8-27(10-14)16-6-1-11(18(20,21)22)9-15(16)17-23-25-26-24-17/h1-6,9,14H,7-8,10H2,(H,23,24,25,26)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Natural resistance-associated macrophage protein 2


(Homo sapiens (Human))
BDBM50361114
PNG
(CHEMBL1933791)
Show SMILES COc1ccc(cc1)-c1ccc2-c3c(CCc2c1)[nH]n(-c1ccccn1)c3=O
Show InChI InChI=1S/C23H19N3O2/c1-28-18-9-5-15(6-10-18)16-7-11-19-17(14-16)8-12-20-22(19)23(27)26(25-20)21-4-2-3-13-24-21/h2-7,9-11,13-14,25H,8,12H2,1H3
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Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching method


Bioorg Med Chem Lett 22: 90-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.069
BindingDB Entry DOI: 10.7270/Q2RJ4JX6
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444139
PNG
(CHEMBL3093395)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1cncc(F)c1)C(F)(F)F |r|
Show InChI InChI=1S/C18H16F4N2O3/c19-13-5-11(7-23-8-13)10-27-14-3-4-24(9-14)16-2-1-12(18(20,21)22)6-15(16)17(25)26/h1-2,5-8,14H,3-4,9-10H2,(H,25,26)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444141
PNG
(CHEMBL3093393)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccc(F)cn1)C(F)(F)F |r|
Show InChI InChI=1S/C18H16F4N2O3/c19-12-2-3-13(23-8-12)10-27-14-5-6-24(9-14)16-4-1-11(18(20,21)22)7-15(16)17(25)26/h1-4,7-8,14H,5-6,9-10H2,(H,25,26)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Phosphodiesterase 9A


(Homo sapiens (Human))
BDBM50398792
PNG
(CHEMBL2177503)
Show SMILES C[C@@H](N1CCC(C1)c1ccccc1)c1nc2n(ncc2c(=O)[nH]1)C1CCCC1 |r|
Show InChI InChI=1S/C22H27N5O/c1-15(26-12-11-17(14-26)16-7-3-2-4-8-16)20-24-21-19(22(28)25-20)13-23-27(21)18-9-5-6-10-18/h2-4,7-8,13,15,17-18H,5-6,9-12,14H2,1H3,(H,24,25,28)/t15-,17?/m1/s1
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Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assay


J Med Chem 55: 9055-68 (2012)


Article DOI: 10.1021/jm3009635
BindingDB Entry DOI: 10.7270/Q2CR5VHK
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444149
PNG
(CHEMBL3093308)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCC1CC1)C(F)(F)F |r|
Show InChI InChI=1S/C16H18F3NO3/c17-16(18,19)11-3-4-14(13(7-11)15(21)22)20-6-5-12(8-20)23-9-10-1-2-10/h3-4,7,10,12H,1-2,5-6,8-9H2,(H,21,22)/t12-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444151
PNG
(CHEMBL3093306)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(Cl)nc1)C(F)(F)F |r|
Show InChI InChI=1S/C17H14ClF3N2O3/c18-15-4-2-11(8-22-15)26-12-5-6-23(9-12)14-3-1-10(17(19,20)21)7-13(14)16(24)25/h1-4,7-8,12H,5-6,9H2,(H,24,25)/t12-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Endothelial lipase


(Homo sapiens (Human))
BDBM50444138
PNG
(CHEMBL3093392)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCc1ccccn1)C(F)(F)F |r|
Show InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1
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Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
BindingDB Entry DOI: 10.7270/Q2P55PZ8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231525
PNG
(US9346818, I-10)
Show SMILES CC1N(CCC2CCN(Cc3ccccc3F)CC2)C(=O)c2cc3OCOc3cc12
Show InChI InChI=1/C24H27FN2O3/c1-16-19-12-22-23(30-15-29-22)13-20(19)24(28)27(16)11-8-17-6-9-26(10-7-17)14-18-4-2-3-5-21(18)25/h2-5,12-13,16-17H,6-11,14-15H2,1H3
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Mus musculus (mouse))
BDBM231540
PNG
(US9346818, I-25)
Show SMILES Fc1cccc(F)c1CN1CCC(CCN2C(=O)c3cc4OCOc4cc3C22CC2)CC1
Show InChI InChI=1S/C25H26F2N2O3/c26-20-2-1-3-21(27)18(20)14-28-9-4-16(5-10-28)6-11-29-24(30)17-12-22-23(32-15-31-22)13-19(17)25(29)7-8-25/h1-3,12-13,16H,4-11,14-15H2
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Zhejiang Hisun Pharmaceutical Co., Ltd.

US Patent


Assay Description
Modified Ellman method (Alvin V. et al. JWS-USC-75-IX Improves Information Processing and Cognitive Function in Animal Models[J]. Journal of Pharmaco...


US Patent US9346818 (2016)


BindingDB Entry DOI: 10.7270/Q2WD3ZFC
More data for this
Ligand-Target Pair
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