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Compile Data Set for Download or QSAR

Found 26 hits with Last Name = 'von kleist' and Initial = 'l'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lanosterol synthase


(Rattus norvegicus)
BDBM50180953
PNG
(CHEMBL3818719)
Show SMILES CCN(CC)C(=O)c1cc2cc(O)c(O)c([N+]([O-])=O)c2cc1C(=O)N(CC)CC
Show InChI InChI=1S/C20H25N3O6/c1-5-21(6-2)19(26)14-9-12-10-16(24)18(25)17(23(28)29)13(12)11-15(14)20(27)22(7-3)8-4/h9-11,24-25H,5-8H2,1-4H3
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n/an/a 54n/an/an/an/an/an/a



Caprotec Bioanalytics GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ...


J Med Chem 59: 4664-75 (2016)


BindingDB Entry DOI: 10.7270/Q2WD42HW
More data for this
Ligand-Target Pair
Lanosterol synthase


(Rattus norvegicus)
BDBM50108877
PNG
((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)
Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
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n/an/a 127n/an/an/an/an/an/a



Caprotec Bioanalytics GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ...


J Med Chem 59: 4664-75 (2016)


BindingDB Entry DOI: 10.7270/Q2WD42HW
More data for this
Ligand-Target Pair
Lanosterol synthase


(Rattus norvegicus)
BDBM50180952
PNG
(CHEMBL3818350)
Show SMILES CCN1C(=O)S\C(=C\c2cc(O)c(O)c(c2)[N+]([O-])=O)C1=O
Show InChI InChI=1S/C12H10N2O6S/c1-2-13-11(17)9(21-12(13)18)5-6-3-7(14(19)20)10(16)8(15)4-6/h3-5,15-16H,2H2,1H3/b9-5+
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n/an/a 179n/an/an/an/an/an/a



Caprotec Bioanalytics GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ...


J Med Chem 59: 4664-75 (2016)


BindingDB Entry DOI: 10.7270/Q2WD42HW
More data for this
Ligand-Target Pair
Lanosterol synthase


(Rattus norvegicus)
BDBM50108879
PNG
((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...)
Show SMILES CCN(CC)C(=O)C(=C\c1cc(O)c(O)c(c1)[N+]([O-])=O)\C#N
Show InChI InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
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Caprotec Bioanalytics GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ...


J Med Chem 59: 4664-75 (2016)


BindingDB Entry DOI: 10.7270/Q2WD42HW
More data for this
Ligand-Target Pair
Lanosterol synthase


(Rattus norvegicus)
BDBM50180954
PNG
(CHEMBL3819488)
Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CC(=O)NCCCCCC(=O)N(C)Cc3ccc(cc3)C(=O)c3cc(O)c(O)c(c3)[N+]([O-])=O)NC(=O)c3ccc(cc3)N=[N+]=[N-])[C@@]1([H])NC(=O)N2 |r|
Show InChI InChI=1/C52H69N11O14S/c1-62(32-34-12-14-35(15-13-34)48(68)37-29-41(63(73)74)49(69)42(64)30-37)46(67)11-3-2-6-20-55-45(66)31-39(57-50(70)36-16-18-38(19-17-36)60-61-53)51(71)56-22-8-24-76-26-28-77-27-25-75-23-7-21-54-44(65)10-5-4-9-43-47-40(33-78-43)58-52(72)59-47/h12-19,29-30,39-40,43,47,64,69H,2-11,20-28,31-33H2,1H3,(H,54,65)(H,55,66)(H,56,71)(H,57,70)(H2,58,59,72)/t39-,40-,43-,47-/s2
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n/an/a 648n/an/an/an/an/an/a



Caprotec Bioanalytics GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ...


J Med Chem 59: 4664-75 (2016)


BindingDB Entry DOI: 10.7270/Q2WD42HW
More data for this
Ligand-Target Pair
Dynamin-1


(Homo sapiens (Human))
BDBM50388829
PNG
(CHEMBL2062753)
Show SMILES CN(C)CCCOc1ccc(\C=C2/SC(=S)N(CC=C)C2=O)cc1
Show InChI InChI=1S/C18H22N2O2S2/c1-4-10-20-17(21)16(24-18(20)23)13-14-6-8-15(9-7-14)22-12-5-11-19(2)3/h4,6-9,13H,1,5,10-12H2,2-3H3/b16-13-
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n/an/a 5.90E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...


ACS Med Chem Lett 3: 352-356 (2012)


Article DOI: 10.1021/ml200284s
BindingDB Entry DOI: 10.7270/Q2V40W83
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446548
PNG
(CHEMBL3110181)
Show SMILES [O-]S(=O)(=O)c1cc2C(=O)N(Cc3ccccc3)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C19H13NO5S/c21-18-15-8-4-7-13-9-14(26(23,24)25)10-16(17(13)15)19(22)20(18)11-12-5-2-1-3-6-12/h1-10H,11H2,(H,23,24,25)/p-1
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n/an/a 6.90E+3n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Dynamin-1


(Homo sapiens (Human))
BDBM50388828
PNG
(CHEMBL2062743)
Show SMILES CCN1C(=S)S\C(=C/c2ccc(OCCCN(C)C)cc2)C1=O
Show InChI InChI=1S/C17H22N2O2S2/c1-4-19-16(20)15(23-17(19)22)12-13-6-8-14(9-7-13)21-11-5-10-18(2)3/h6-9,12H,4-5,10-11H2,1-3H3/b15-12-
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n/an/a 7.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...


ACS Med Chem Lett 3: 352-356 (2012)


Article DOI: 10.1021/ml200284s
BindingDB Entry DOI: 10.7270/Q2V40W83
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446543
PNG
(CHEMBL3110178)
Show SMILES [O-]S(=O)(=O)c1cc2C(=O)N(Cc3ccc(Cl)cc3)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C19H12ClNO5S/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23/h1-9H,10H2,(H,24,25,26)/p-1
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n/an/a 1.00E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446549
PNG
(CHEMBL3110180)
Show SMILES Nc1ccccc1CN1C(=O)c2cccc3cc(cc(C1=O)c23)S([O-])(=O)=O
Show InChI InChI=1S/C19H14N2O5S/c20-16-7-2-1-4-12(16)10-21-18(22)14-6-3-5-11-8-13(27(24,25)26)9-15(17(11)14)19(21)23/h1-9H,10,20H2,(H,24,25,26)/p-1
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n/an/a 1.00E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446544
PNG
(CHEMBL3110188)
Show SMILES [O-]S(=O)(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C19H12FNO5S/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23/h1-9H,10H2,(H,24,25,26)/p-1
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n/an/a 1.20E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446542
PNG
(CHEMBL3110179)
Show SMILES [O-]S(=O)(=O)c1cc2C(=O)N(Cc3ccc(Br)cc3)C(=O)c3cccc(c1)c23
Show InChI InChI=1S/C19H12BrNO5S/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23/h1-9H,10H2,(H,24,25,26)/p-1
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n/an/a 1.50E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446540
PNG
(CHEMBL3110184)
Show SMILES Cc1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C20H15NO5S/c1-12-5-7-13(8-6-12)11-21-19(22)16-4-2-3-14-9-15(27(24,25)26)10-17(18(14)16)20(21)23/h2-10H,11H2,1H3,(H,24,25,26)/p-1
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n/an/a 1.50E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446546
PNG
(CHEMBL3110183)
Show SMILES COc1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C20H15NO6S/c1-27-14-7-5-12(6-8-14)11-21-19(22)16-4-2-3-13-9-15(28(24,25)26)10-17(18(13)16)20(21)23/h2-10H,11H2,1H3,(H,24,25,26)/p-1
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n/an/a 1.60E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446551
PNG
(CHEMBL3110174)
Show SMILES Nc1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C19H14N2O5S/c20-13-6-4-11(5-7-13)10-21-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23/h1-9H,10,20H2,(H,24,25,26)/p-1
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n/an/a 1.80E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Dynamin-1


(Homo sapiens (Human))
BDBM50388827
PNG
(CHEMBL2062731)
Show SMILES SC1=NC(=O)C(S1)=Cc1cc(Cl)cc(Cl)c1 |w:7.8,t:1|
Show InChI InChI=1S/C10H5Cl2NOS2/c11-6-1-5(2-7(12)4-6)3-8-9(14)13-10(15)16-8/h1-4H,(H,13,14,15)
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n/an/a 1.81E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...


ACS Med Chem Lett 3: 352-356 (2012)


Article DOI: 10.1021/ml200284s
BindingDB Entry DOI: 10.7270/Q2V40W83
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446547
PNG
(CHEMBL3110182)
Show SMILES Oc1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C19H13NO6S/c21-13-6-4-11(5-7-13)10-20-18(22)15-3-1-2-12-8-14(27(24,25)26)9-16(17(12)15)19(20)23/h1-9,21H,10H2,(H,24,25,26)/p-1
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n/an/a 2.20E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446553
PNG
(CHEMBL3110161)
Show SMILES OC(=O)c1ccc(N2C(=O)c3cccc4cc(cc(C2=O)c34)[N+]([O-])=O)c(O)c1
Show InChI InChI=1S/C19H10N2O7/c22-15-7-10(19(25)26)4-5-14(15)20-17(23)12-3-1-2-9-6-11(21(27)28)8-13(16(9)12)18(20)24/h1-8,22H,(H,25,26)
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n/an/a 8.00E+4n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446552
PNG
(CHEMBL3110162)
Show SMILES OC(=O)c1cc(O)ccc1N1C(=O)c2cccc3cc(cc(C1=O)c23)[N+]([O-])=O
Show InChI InChI=1S/C19H10N2O7/c22-11-4-5-15(13(8-11)19(25)26)20-17(23)12-3-1-2-9-6-10(21(27)28)7-14(16(9)12)18(20)24/h1-8,22H,(H,25,26)
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Dynamin-1


(Homo sapiens (Human))
BDBM50388830
PNG
(CHEMBL2062756)
Show SMILES OC(=O)CN1C(=S)S\C(=C/c2csc3ccc(Cl)cc23)C1=O
Show InChI InChI=1S/C14H8ClNO3S3/c15-8-1-2-10-9(4-8)7(6-21-10)3-11-13(19)16(5-12(17)18)14(20)22-11/h1-4,6H,5H2,(H,17,18)/b11-3-
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n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re...


ACS Med Chem Lett 3: 352-356 (2012)


Article DOI: 10.1021/ml200284s
BindingDB Entry DOI: 10.7270/Q2V40W83
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446555
PNG
(CHEMBL3110160)
Show SMILES CCN1C(=O)c2cccc3c(N)c(cc(C1=O)c23)S([O-])(=O)=O
Show InChI InChI=1S/C14H12N2O5S/c1-2-16-13(17)8-5-3-4-7-11(8)9(14(16)18)6-10(12(7)15)22(19,20)21/h3-6H,2,15H2,1H3,(H,19,20,21)/p-1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446545
PNG
(CHEMBL3110186)
Show SMILES OC(=O)c1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C20H13NO7S/c22-18-15-3-1-2-13-8-14(29(26,27)28)9-16(17(13)15)19(23)21(18)10-11-4-6-12(7-5-11)20(24)25/h1-9H,10H2,(H,24,25)(H,26,27,28)/p-1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446541
PNG
(CHEMBL3110185)
Show SMILES CN(C)c1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C21H18N2O5S/c1-22(2)15-8-6-13(7-9-15)12-23-20(24)17-5-3-4-14-10-16(29(26,27)28)11-18(19(14)17)21(23)25/h3-11H,12H2,1-2H3,(H,26,27,28)/p-1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446550
PNG
(CHEMBL3110177)
Show SMILES Nc1cccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)c1
Show InChI InChI=1S/C19H14N2O5S/c20-13-5-1-3-11(7-13)10-21-18(22)15-6-2-4-12-8-14(27(24,25)26)9-16(17(12)15)19(21)23/h1-9H,10,20H2,(H,24,25,26)/p-1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446556
PNG
(CHEMBL3110158)
Show SMILES Nc1ccc(CN2C(=O)c3cccc4c(N)c(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C19H15N3O5S/c20-11-6-4-10(5-7-11)9-22-18(23)13-3-1-2-12-16(13)14(19(22)24)8-15(17(12)21)28(25,26)27/h1-8H,9,20-21H2,(H,25,26,27)/p-1
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n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446554
PNG
(CHEMBL3110159)
Show SMILES CCCN1C(=O)c2cccc3c(N)c(cc(C1=O)c23)S([O-])(=O)=O
Show InChI InChI=1S/C15H14N2O5S/c1-2-6-17-14(18)9-5-3-4-8-12(9)10(15(17)19)7-11(13(8)16)23(20,21)22/h3-5,7H,2,6,16H2,1H3,(H,20,21,22)/p-1
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n/an/a 1.20E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
BindingDB Entry DOI: 10.7270/Q2HQ41DT
More data for this
Ligand-Target Pair