Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...) | BDBM50021776 (2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-pur...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GLSynthesis Inc. Curated by ChEMBL | Assay Description Inhibition of Herpes simplex virus 1 recombinant thymidine kinase | Antimicrob Agents Chemother 51: 2028-34 (2007) Article DOI: 10.1128/AAC.01284-06 BindingDB Entry DOI: 10.7270/Q2RN38R9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thymidine kinase (Human herpesvirus 2) | BDBM50021776 (2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-pur...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GLSynthesis Inc. Curated by ChEMBL | Assay Description Inhibition of Herpes simplex virus 2 recombinant thymidine kinase | Antimicrob Agents Chemother 51: 2028-34 (2007) Article DOI: 10.1128/AAC.01284-06 BindingDB Entry DOI: 10.7270/Q2RN38R9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidine kinase (Macacine herpesvirus 1) | BDBM50021776 (2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-pur...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
GLSynthesis Inc. Curated by ChEMBL | Assay Description Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylation | Antimicrob Agents Chemother 51: 2028-34 (2007) Article DOI: 10.1128/AAC.01284-06 BindingDB Entry DOI: 10.7270/Q2RN38R9 | |||||||||||
More data for this Ligand-Target Pair |