Compile Data Set for Download or QSAR

Found 2698 hits of ic50 for UniProtKB: P68400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II subunit alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM218843 (US9303033, A1, Example 5) Show SMILES Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 Show InChI InChI=1S/C16H12ClN7O2/c17-9-2-1-3-10(5-9)20-13-6-12(18)24-14(22-13)8(7-19-24)4-11-15(25)23-16(26)21-11/h1-7H,18H2,(H,20,22)(H2,21,23,25,26)/b11-4-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142829 (US8940736, 391) Show SMILES Cc1nc(Nc2nc(Nc3ccc4n(C)nc(C#N)c4c3)nn3c(cnc23)[N+]#[C-])nn1C Show InChI InChI=1S/C19H15N13/c1-10-23-18(28-30(10)3)25-16-17-22-9-15(21-2)32(17)29-19(26-16)24-11-5-6-14-12(7-11)13(8-20)27-31(14)4/h5-7,9H,1,3-4H3,(H2,24,25,26,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142817 (US8940736, 285) Show SMILES COC(=O)N[C@@H]1CCN(C[C@@H]1F)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H22ClFN10O2/c1-37-23(36)31-16-4-5-34(11-15(16)25)18-7-12(8-26)6-17(19(18)24)30-22-32-20(29-13-2-3-13)21-28-10-14(9-27)35(21)33-22/h6-7,10,13,15-16H,2-5,11H2,1H3,(H,31,36)(H2,29,30,32,33)/t15-,16+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142774 (US8940736, 6) Show SMILES Cn1nc(C#N)c2cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)ccc12 Show InChI InChI=1S/C18H14N10/c1-27-15-5-4-11(6-13(15)14(8-20)25-27)23-18-24-16(22-10-2-3-10)17-21-9-12(7-19)28(17)26-18/h4-6,9-10H,2-3H2,1H3,(H2,22,23,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142835 (US8940736, 402) Show SMILES OCc1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C17H13ClN8O/c18-14-10(8-27)3-9(5-19)4-13(14)23-17-24-15(22-11-1-2-11)16-21-7-12(6-20)26(16)25-17/h3-4,7,11,27H,1-2,8H2,(H2,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142775 (US8940736, 7) Show SMILES OC1CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C20H18ClN9O/c21-17-15(5-11(7-22)6-16(17)29-4-3-14(31)10-29)26-20-27-18(25-12-1-2-12)19-24-9-13(8-23)30(19)28-20/h5-6,9,12,14,31H,1-4,10H2,(H2,25,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142806 (US8940736, 229) Show SMILES CC(=O)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C23H22ClN9O/c1-13(34)32-6-4-15(5-7-32)18-8-14(10-25)9-19(20(18)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)33(22)31-23/h8-9,12,15-16H,2-7H2,1H3,(H2,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142793 (US8940736, 161) Show SMILES COC1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O/c1-36-18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142784 (US8940736, 117) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCC(CC1)NC1CCS(=O)(=O)C1)C#N Show InChI InChI=1S/C25H27ClN10O2S/c26-22-20(32-25-33-23(31-16-1-2-16)24-29-13-19(12-28)36(24)34-25)9-15(11-27)10-21(22)35-6-3-17(4-7-35)30-18-5-8-39(37,38)14-18/h9-10,13,16-18,30H,1-8,14H2,(H2,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142832 (US8940736, 395) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142777 (US8940736, 49) Show SMILES Clc1c(NN2CCOCC2)cc(cc1Nc1nc(NC2CC2)c2ncc(C#N)n2n1)C#N Show InChI InChI=1S/C20H19ClN10O/c21-17-15(7-12(9-22)8-16(17)28-30-3-5-32-6-4-30)26-20-27-18(25-13-1-2-13)19-24-11-14(10-23)31(19)29-20/h7-8,11,13,28H,1-6H2,(H2,25,26,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142834 (US8940736, 399) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1C=C)C#N Show InChI InChI=1S/C18H13ClN8/c1-2-11-5-10(7-20)6-14(15(11)19)24-18-25-16(23-12-3-4-12)17-22-9-13(8-21)27(17)26-18/h2,5-6,9,12H,1,3-4H2,(H2,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142792 (US8940736, 160) Show SMILES CS(=O)(=O)C1CCN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C24H25ClN10O2S/c1-38(36,37)18-4-5-33(13-18)17-11-34(12-17)20-7-14(8-26)6-19(21(20)25)30-24-31-22(29-15-2-3-15)23-28-10-16(9-27)35(23)32-24/h6-7,10,15,17-18H,2-5,11-13H2,1H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142831 (US8940736, 394) Show SMILES CCNc1nc(Nc2ccc3n(nc(C#N)c3c2)C2CCN(C[C@H](C)O)CC2)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C24H27N11O/c1-3-27-22-23-28-13-18(11-25)35(23)32-24(30-22)29-16-4-5-21-19(10-16)20(12-26)31-34(21)17-6-8-33(9-7-17)14-15(2)36/h4-5,10,13,15,17,36H,3,6-9,14H2,1-2H3,(H2,27,29,30,32)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142816 (US8940736, 281) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1OP(O)(O)=O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H24ClN10O6P/c1-39-23(35)30-15-4-5-33(11-18(15)40-41(36,37)38)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18H,2-5,11H2,1H3,(H,30,35)(H2,36,37,38)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142794 (US8940736, 163) Show SMILES COC(=O)N[C@@H]1CN(C[C@H]1C)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C26H28ClN11O2/c1-14-10-36(13-20(14)33-26(39)40-2)18-11-37(12-18)21-6-15(7-28)5-19(22(21)27)32-25-34-23(31-16-3-4-16)24-30-9-17(8-29)38(24)35-25/h5-6,9,14,16,18,20H,3-4,10-13H2,1-2H3,(H,33,39)(H2,31,32,34,35)/t14-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.270	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142820 (US8940736, 319) Show SMILES CC(=O)N1CC(C1)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C26H27ClN10O/c1-15(38)36-13-20(14-36)35-6-4-17(5-7-35)21-8-16(10-28)9-22(23(21)27)32-26-33-24(31-18-2-3-18)25-30-12-19(11-29)37(25)34-26/h8-9,12,17-18,20H,2-7,13-14H2,1H3,(H2,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142778 (US8940736, 55) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1N1CCN(CC1)C1CCOC1)C#N Show InChI InChI=1S/C24H25ClN10O/c25-21-19(30-24-31-22(29-16-1-2-16)23-28-13-18(12-27)35(23)32-24)9-15(11-26)10-20(21)34-6-4-33(5-7-34)17-3-8-36-14-17/h9-10,13,16-17H,1-8,14H2,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142818 (US8940736, 313) Show SMILES FC1CN(CCN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1Cl)C#N)C1COC1 Show InChI InChI=1S/C24H24ClFN10O/c1-28-20-9-29-23-22(30-16-2-3-16)32-24(33-36(20)23)31-18-6-14(8-27)7-19(21(18)25)35-5-4-34(10-15(26)11-35)17-12-37-13-17/h6-7,9,15-17H,2-5,10-13H2,(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142795 (US8940736, 167) Show SMILES OC1CN(C1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C22H21ClN10O/c23-19-17(3-12(5-24)4-18(19)32-8-15(9-32)31-10-16(34)11-31)28-22-29-20(27-13-1-2-13)21-26-7-14(6-25)33(21)30-22/h3-4,7,13,15-16,34H,1-2,8-11H2,(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142790 (US8940736, 133) Show SMILES O[C@H]1C[C@H](C1)NC1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r,wU:3.5,1.0,(10.45,-1.86,;9.11,-2.63,;8.72,-4.11,;7.23,-3.72,;7.63,-2.23,;5.89,-4.49,;4.56,-3.72,;3.23,-4.49,;1.89,-3.72,;1.89,-2.18,;3.23,-1.41,;4.56,-2.18,;.56,-1.41,;.56,.13,;-.77,.9,;-2.11,.13,;-2.11,-1.41,;-3.44,-2.18,;-4.78,-1.41,;-4.78,.13,;-6.11,.9,;-6.11,2.44,;-7.44,3.21,;-8.21,4.55,;-8.98,3.21,;-7.44,.13,;-8.91,.61,;-9.81,-.64,;-8.91,-1.88,;-9.68,-3.21,;-10.45,-4.55,;-7.44,-1.41,;-6.11,-2.18,;-.77,-2.18,;-.77,-3.72,;-.77,2.44,;-.77,3.98,)| Show InChI InChI=1S/C25H27ClN10O/c26-22-20(32-25-33-23(31-15-1-2-15)24-29-13-18(12-28)36(24)34-25)7-14(11-27)8-21(22)35-5-3-16(4-6-35)30-17-9-19(37)10-17/h7-8,13,15-17,19,30,37H,1-6,9-10H2,(H2,31,32,33,34)/t17-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142779 (US8940736, 57) Show SMILES C[C@@H](O)CN1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H25ClN10O/c1-14(35)13-32-4-6-33(7-5-32)19-9-15(10-25)8-18(20(19)24)29-23-30-21(28-16-2-3-16)22-27-12-17(11-26)34(22)31-23/h8-9,12,14,16,35H,2-7,13H2,1H3,(H2,28,29,30,31)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142802 (US8940736, 207) Show SMILES CN1CCC(=CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |c:4| Show InChI InChI=1S/C22H20ClN9/c1-31-6-4-14(5-7-31)17-8-13(10-24)9-18(19(17)23)28-22-29-20(27-15-2-3-15)21-26-12-16(11-25)32(21)30-22/h4,8-9,12,15H,2-3,5-7H2,1H3,(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142827 (US8940736, 382) Show SMILES CN1CCN(CC1)C1CN(C1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1F)C#N Show InChI InChI=1S/C24H26FN11/c1-27-20-12-28-23-22(29-16-3-4-16)31-24(32-36(20)23)30-18-9-15(11-26)10-19(21(18)25)35-13-17(14-35)34-7-5-33(2)6-8-34/h9-10,12,16-17H,3-8,13-14H2,2H3,(H2,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.390	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142796 (US8940736, 173) Show SMILES COC(=O)N[C@@H]1CCN(C[C@H]1O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H23ClN10O3/c1-37-23(36)30-15-4-5-33(11-18(15)35)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18,35H,2-5,11H2,1H3,(H,30,36)(H2,28,29,31,32)/t15-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Tartu Curated by ChEMBL					Assay Description Displacement of 5-TAMRA-labeled ARC-1530 from CK2alpha (unknown origin) (1 to 335 residues) after 15 to 60 mins by luminescence assay				Bioorg Med Chem 26: 5062-5068 (2018) Article DOI: 10.1016/j.bmc.2018.09.003 BindingDB Entry DOI: 10.7270/Q26112V7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142822 (US8940736, 328) Show SMILES CCNc1nc(Nc2cc(cc(N3CC[C@H](NC(=O)OC)[C@@H](O)C3)c2Cl)C#N)nn2c(cnc12)[N+]#[C-] |r| Show InChI InChI=1S/C22H23ClN10O3/c1-4-26-19-20-27-10-17(25-2)33(20)31-21(30-19)28-14-7-12(9-24)8-15(18(14)23)32-6-5-13(16(34)11-32)29-22(35)36-3/h7-8,10,13,16,34H,4-6,11H2,1,3H3,(H,29,35)(H2,26,28,30,31)/t13-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142797 (US8940736, 174) Show SMILES COC(=O)N[C@H]1CCN(C[C@@H]1O)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C23H23ClN10O3/c1-37-23(36)30-15-4-5-33(11-18(15)35)17-7-12(8-25)6-16(19(17)24)29-22-31-20(28-13-2-3-13)21-27-10-14(9-26)34(21)32-22/h6-7,10,13,15,18,35H,2-5,11H2,1H3,(H,30,36)(H2,28,29,31,32)/t15-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.720	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM92757 (CX-5279) Show SMILES [O-]C(=O)c1ccc2c(c1)nc(Nc1cccc(c1)C(F)(F)F)c1nc(NC3CC3)ncc21 Show InChI InChI=1S/C22H16F3N5O2/c23-22(24,25)12-2-1-3-14(9-12)27-19-18-16(10-26-21(30-18)28-13-5-6-13)15-7-4-11(20(31)32)8-17(15)29-19/h1-4,7-10,13H,5-6H2,(H,27,29)(H,31,32)(H,26,28,30)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
Venetian Institute of Molecular Medicine					Assay Description Phosphorylation assay using casein kinase 2.				Biochemistry 50: 8478-88 (2011) Article DOI: 10.1021/bi2008382 BindingDB Entry DOI: 10.7270/Q2125R86
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human CK2alpha in presence of ATP at Km concentration by radiometric filter-binding assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112770 BindingDB Entry DOI: 10.7270/Q2DN48PP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113318 BindingDB Entry DOI: 10.7270/Q25Q5115
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CK2alpha by radiometric assay				J Med Chem 54: 635-54 (2011) Article DOI: 10.1021/jm101251q BindingDB Entry DOI: 10.7270/Q2J67H7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assay				J Med Chem 54: 635-54 (2011) Article DOI: 10.1021/jm101251q BindingDB Entry DOI: 10.7270/Q2J67H7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112267 BindingDB Entry DOI: 10.7270/Q2M330H3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142791 (US8940736, 150) Show SMILES COC(=O)N[C@@H]1CN(C[C@@H]1C)C1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C28H32ClN11O2/c1-16-14-39(15-22(16)35-28(41)42-2)19-5-7-38(8-6-19)23-10-17(11-30)9-21(24(23)29)34-27-36-25(33-18-3-4-18)26-32-13-20(12-31)40(26)37-27/h9-10,13,16,18-19,22H,3-8,14-15H2,1-2H3,(H,35,41)(H2,33,34,36,37)/t16-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.31	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142837 (US8940736, 409) Show SMILES Clc1c(NC2CCN(CC2)C2COC2)cc(cc1Nc1nc(NC2CC2)c2ncc(C#N)n2n1)C#N Show InChI InChI=1S/C24H25ClN10O/c25-21-19(29-16-3-5-34(6-4-16)18-12-36-13-18)7-14(9-26)8-20(21)31-24-32-22(30-15-1-2-15)23-28-11-17(10-27)35(23)33-24/h7-8,11,15-16,18,29H,1-6,12-13H2,(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.32	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142825 (US8940736, 364) Show SMILES CCNc1nc(Nc2cc(cc(N3CCC(CC3)NC[C@@H](C)O)c2Cl)C#N)nn2c(cnc12)[N+]#[C-] |r| Show InChI InChI=1S/C23H27ClN10O/c1-4-27-21-22-29-13-19(26-3)34(22)32-23(31-21)30-17-9-15(11-25)10-18(20(17)24)33-7-5-16(6-8-33)28-12-14(2)35/h9-10,13-14,16,28,35H,4-8,12H2,1-2H3,(H2,27,30,31,32)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.33	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142804 (US8940736, 221) Show SMILES OCC1(CO)CC(C1)N1CCC(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C27H30ClN9O2/c28-23-21(17-3-5-36(6-4-17)19-9-27(10-19,14-38)15-39)7-16(11-29)8-22(23)33-26-34-24(32-18-1-2-18)25-31-13-20(12-30)37(25)35-26/h7-8,13,17-19,38-39H,1-6,9-10,14-15H2,(H2,32,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.34	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142807 (US8940736, 238) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)cc(cc1C1CCN(CC1)C(=O)OC1COC1)C#N Show InChI InChI=1S/C25H24ClN9O3/c26-21-19(15-3-5-34(6-4-15)25(36)38-18-12-37-13-18)7-14(9-27)8-20(21)31-24-32-22(30-16-1-2-16)23-29-11-17(10-28)35(23)33-24/h7-8,11,15-16,18H,1-6,12-13H2,(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.35	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142780 (US8940736, 60) Show SMILES COC(=O)N1CCC(CC1)N1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C27H30ClN11O2/c1-41-27(40)38-6-4-19(5-7-38)36-8-10-37(11-9-36)22-13-17(14-29)12-21(23(22)28)33-26-34-24(32-18-2-3-18)25-31-16-20(15-30)39(25)35-26/h12-13,16,18-19H,2-11H2,1H3,(H2,32,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.35	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142799 (US8940736, 179) Show SMILES O[C@@H]1CN(CC[C@H]1NC(=O)OC1COC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N |r| Show InChI InChI=1S/C25H25ClN10O4/c26-21-18(31-24-33-22(30-14-1-2-14)23-29-9-15(8-28)36(23)34-24)5-13(7-27)6-19(21)35-4-3-17(20(37)10-35)32-25(38)40-16-11-39-12-16/h5-6,9,14,16-17,20,37H,1-4,10-12H2,(H,32,38)(H2,30,31,33,34)/t17-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.36	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142826 (US8940736, 374) Show SMILES CCNc1nc(Nc2cc(cc(N3CC[C@@H]4[C@@H](C3)OCCN4C3COC3)c2Cl)C#N)nn2c(cnc12)C#N |r| Show InChI InChI=1S/C25H27ClN10O2/c1-2-29-23-24-30-11-16(10-28)36(24)33-25(32-23)31-18-7-15(9-27)8-20(22(18)26)34-4-3-19-21(12-34)38-6-5-35(19)17-13-37-14-17/h7-8,11,17,19,21H,2-6,12-14H2,1H3,(H2,29,31,32,33)/t19-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.37	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142782 (US8940736, 108) Show SMILES FC1(F)CC(C1)NC1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)c1Cl)C#N Show InChI InChI=1S/C25H25ClF2N10/c1-30-20-13-31-23-22(33-15-2-3-15)35-24(36-38(20)23)34-18-8-14(12-29)9-19(21(18)26)37-6-4-16(5-7-37)32-17-10-25(27,28)11-17/h8-9,13,15-17,32H,2-7,10-11H2,(H2,33,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.37	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142800 (US8940736, 184) Show SMILES CN1CCN(CC(=O)N[C@@H]2CCN(C[C@H]2O)c2cc(cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)C#N)CC1 |r| Show InChI InChI=1S/C28H33ClN12O2/c1-38-6-8-39(9-7-38)16-24(43)34-20-4-5-40(15-23(20)42)22-11-17(12-30)10-21(25(22)29)35-28-36-26(33-18-2-3-18)27-32-14-19(13-31)41(27)37-28/h10-11,14,18,20,23,42H,2-9,15-16H2,1H3,(H,34,43)(H2,33,35,36,37)/t20-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.37	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142843 (US8940736, 428) Show SMILES CCNc1nc(Nc2cc(cc(N3CCN(CC(F)F)CC3)c2Cl)C#N)nn2c(cnc12)C#N Show InChI InChI=1S/C21H21ClF2N10/c1-2-27-19-20-28-11-14(10-26)34(20)31-21(30-19)29-15-7-13(9-25)8-16(18(15)22)33-5-3-32(4-6-33)12-17(23)24/h7-8,11,17H,2-6,12H2,1H3,(H2,27,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.39	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142836 (US8940736, 408) Show SMILES CCNc1nc(Nc2cc(cc(N3CCN(CC3)C3COC3)c2Cl)C#N)nn2c(cnc12)C#N Show InChI InChI=1S/C22H23ClN10O/c1-2-26-20-21-27-11-15(10-25)33(21)30-22(29-20)28-17-7-14(9-24)8-18(19(17)23)32-5-3-31(4-6-32)16-12-34-13-16/h7-8,11,16H,2-6,12-13H2,1H3,(H2,26,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.39	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142776 (US8940736, 23) Show SMILES CN1CC2(C1)CN(C2)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C#N Show InChI InChI=1S/C22H21ClN10/c1-31-9-22(10-31)11-32(12-22)17-5-13(6-24)4-16(18(17)23)28-21-29-19(27-14-2-3-14)20-26-8-15(7-25)33(20)30-21/h4-5,8,14H,2-3,9-12H2,1H3,(H2,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142819 (US8940736, 314) Show SMILES Clc1c(Nc2nc(NC3CC3)c3ncc([N+]#[C-])n3n2)cc(cc1N1CCN(C2COC2)C(C1)C(=O)N1CCOCC1)C#N Show InChI InChI=1S/C28H30ClN11O3/c1-31-23-13-32-26-25(33-18-2-3-18)35-28(36-40(23)26)34-20-10-17(12-30)11-21(24(20)29)38-4-5-39(19-15-43-16-19)22(14-38)27(41)37-6-8-42-9-7-37/h10-11,13,18-19,22H,2-9,14-16H2,(H2,33,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142814 (US8940736, 274) Show SMILES CC1(COC1)N1CCN(CC1)c1cc(cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl)C(F)F Show InChI InChI=1S/C24H26ClF2N9O/c1-24(12-37-13-24)35-6-4-34(5-7-35)18-9-14(20(26)27)8-17(19(18)25)31-23-32-21(30-15-2-3-15)22-29-11-16(10-28)36(22)33-23/h8-9,11,15,20H,2-7,12-13H2,1H3,(H2,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.42	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM142824 (US8940736, 348) Show SMILES CCNc1nc(Nc2cc(cc(C3CCNCC3)c2Cl)C#N)nn2c(cnc12)[N+]#[C-] Show InChI InChI=1S/C20H20ClN9/c1-3-25-18-19-26-11-16(23-2)30(19)29-20(28-18)27-15-9-12(10-22)8-14(17(15)21)13-4-6-24-7-5-13/h8-9,11,13,24H,3-7H2,1H3,(H2,25,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.42	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8940736 (2015) BindingDB Entry DOI: 10.7270/Q2QV3K72
					More data for this Ligand-Target Pair

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