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Compile Data Set for Download or QSAR

Found 485 hits of ec50 data for polymerid = 1022   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 4
PNG
((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-me...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00100n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 41
PNG
(4-[(Z)-1-(2-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00100n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 79
PNG
(CHEM-US-00174)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00300n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 85
PNG
(CHEM-US-00182)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00500n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 80
PNG
(CHEM-US-00175)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00700n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 76
PNG
(4-[[3-[2-(Pyridin-4-ylmethoxy)phenyl]-1H-pyrazol-4...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.00700n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 78
PNG
(CHEM-US-00173)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0110n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 77
PNG
(CHEM-US-00172)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0110n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 5
PNG
((E)-2-(4-Chlorophenoxy)-1-(2,4- dimethoxyphenyl)-3...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0120n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 84
PNG
(4-[[3-(2-Fluoro-3-hydroxyphenyl)-1H-pyrazol-4-yl]o...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0170n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 25
PNG
((E)-1-[(2-Chlorobenzoyl)-2- (dimethylamino)vinylox...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0180n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 86
PNG
(CHEM-US-00183)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0280n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 33
PNG
(Methyl 3-[(E)-2-(4-cyanophenoxy)- 3-(dimethylamino...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0310n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 52
PNG
(CHEM-US-00129)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0320n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 74
PNG
(4-[[3-[3-[[3-Fluoro-3-(hydroxymethyl)azetidin-1-yl...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0360n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 70
PNG
(CHEM-US-00162)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0380n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 54
PNG
(CHEM-US-00131)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0460n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 69
PNG
(4-[[3-[3-[(6-Fluoropyridin-2-yl)oxymethyl]phenyl]-...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0480n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 51
PNG
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0510n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 50
PNG
(4-[[3-[3-(Pyridin-2-ylmethoxy)phenyl]-1H-pyrazol-4...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0520n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 6
PNG
((E)-2-(4-Chlorophenoxy)-1-(2- chlorophenyl)-3-(dim...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0520n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 36
PNG
(4-[(Z)-1-(3-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0530n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 35
PNG
(4-[(Z)-1-(2-Chloro-3-fluoro- benzoyl)- (dimethylam...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0690n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 8
PNG
((E)-2-(4-Chlorophenoxy)-1-[2- (difluoromethoxy)phe...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0760n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 48
PNG
(4-[[3-(3-Hydroxyphenyl)-1H-pyrazol-4-yl]oxy]benzon...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0830n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 49
PNG
(4-[[3-[3-(Hydroxymethyl)phenyl]-1H-pyrazol-4-yl]ox...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0850n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 56
PNG
(CHEM-US-00133)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.0940n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (Human))
BDBM249226
PNG
(US9458135, 14)
Show SMILES CN1C(=O)CCc2cc(ccc12)-c1cncc(CSc2cccc(C)n2)c1
Show InChI InChI=1S/C22H21N3OS/c1-15-4-3-5-21(24-15)27-14-16-10-19(13-23-12-16)17-6-8-20-18(11-17)7-9-22(26)25(20)2/h3-6,8,10-13H,7,9,14H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.100n/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...


US Patent US9458135 (2016)

More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 59
PNG
(4-[[5-(3-Butoxyphenyl)-1H-pyrazol-4-yl]oxy]benzoni...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.102n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 28
PNG
(4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.134n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 75
PNG
(4-[[3-[3-(Morpholin-4-ylmethyl)phenyl]-1H-pyrazol-...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.139n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 47
PNG
(CHEM-US-00117)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.159n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 15
PNG
((E)-2-(4-Chlorophenoxy)-1-(2,4- difluorophenyl)-3-...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.159n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 29
PNG
((E)-1-[(2,3-Difluorobenzoyl)-2-(dimethylamino)viny...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.161n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 9
PNG
((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-fl...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.167n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 81
PNG
(CHEM-US-00176)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.171n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 30
PNG
(4-[(E)-1-(3-Chloro-2-fluoro- benzoyl)-2- (dimethyl...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.191n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 53
PNG
(CHEM-US-00130)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.198n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 34
PNG
((E)-1-(2-Chloro-3-fluoro-phenyl)-2- (4-chloropheno...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.262n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 55
PNG
(CHEM-US-00132)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.288n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 38
PNG
(Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dim...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.321n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 42
PNG
(5-(2-Chloro-4-methylsulfonylphenyl)-4-(4-chlorophe...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.345n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 24
PNG
((E)-2-(4-Chloro-2-fluoro-phenoxy)- 1-(2-chlorophen...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.350n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 19
PNG
((E)-1-(2-Chlorophenyl)-2-[(6- chloro-3-pyridyl)oxy...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
n/an/an/an/a 0.387n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial


(Homo sapiens (Human))
BDBM101354
PNG
(US9695151, 20)
Show SMILES CCS(=O)(=O)N1CCC(CC1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C
Show InChI InChI=1S/C23H29ClN4O3S/c1-5-32(30,31)27-10-8-17(9-11-27)26(4)18-13-19(15-25-14-18)28-22(29)20-7-6-16(24)12-21(20)23(28,2)3/h6-7,12-15,17H,5,8-11H2,1-4H3
PDB

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PC cid
PC sid
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US Patent
n/an/an/an/a 0.400n/an/an/a37



Hoffmann-La Roche Inc.

US Patent


Assay Description
G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...


US Patent US9695151 (2017)

More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 73
PNG
(CHEM-US-00165)
PDB

KEGG

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Article
n/an/an/an/a 0.411n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 11
PNG
((E)-1-(4-Chloro-2-fluoro-phenyl)-2- (4-chloropheno...)
PDB

KEGG

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Article
n/an/an/an/a 0.433n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 18
PNG
(4-[(Z)-2-(Dimethylamino)-1-(4- methylsulfonylbenzo...)
PDB

KEGG

UniProtKB/SwissProt

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Article
n/an/an/an/a 0.462n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 17
PNG
((E)-1-(2-Chloro-4-methylsulfanyl- phenyl)-2-(4-chl...)
PDB

KEGG

UniProtKB/SwissProt

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Article
n/an/an/an/a 0.522n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
Cytochrome P450 11B1


(Homo sapiens (Human))
US9790217, 32
PNG
(4-[(Z)-1-(3-Chlorobenzoyl)-2- (dimethylamino)vinyl...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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UniChem
Article
n/an/an/an/a 0.542n/an/an/an/a



Abbott Laboratories





J Med Chem 50: 1983-7 (2007)


Article DOI: 10.1021/jm061436d
More data for this
Ligand-Target Pair
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