Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil elastase (Homo sapiens (Human)) | BDBM50303364 (1-(4-((Benzo[d]oxazol-2-ylthio)methyl)phenyl)-3,3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50303363 (2-(4-(3,3-Diethyl-2,4-dioxoazetidin-1-yl)benzylthi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50235614 (3,3-diethyl-1-(4-tolyl)azetidine-2,4-dione | 3,3-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 48.2 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50235612 (1-(4-chlorophenyl)-3,3-diethylazetidine-2,4-dione ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 57.9 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50303365 (1-(2-((Benzo[d]oxazol-2-ylthio)methyl)phenyl)-3,3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 205 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50303362 (1-(2-((Benzo[d]thiazol-2-ylthio)methyl)phenyl)-3,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 283 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50303367 (1-(2-((5-Phenyl-1,3,4-oxadiazol-2-ylthio)methyl)ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 353 | n/a | n/a | n/a | n/a | n/a |
University of Lisbon Curated by ChEMBL | Assay Description Inhibition of human leukocyte elastase after 20 mins | J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50084227 (2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a |
University of Leipzig Curated by ChEMBL | Assay Description Inhibitory activity of the compound was tested against human leukocyte elastase | J Med Chem 42: 5437-47 (2000) BindingDB Entry DOI: 10.7270/Q2K936RG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50084228 (2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Leipzig Curated by ChEMBL | Assay Description Inhibitory activity of the compound was tested against human leukocyte elastase | J Med Chem 42: 5437-47 (2000) BindingDB Entry DOI: 10.7270/Q2K936RG | |||||||||||
More data for this Ligand-Target Pair |