Compile Data Set for Download or QSAR

Found 195 hits of ic50 data for polymerid = 106,1114,50001207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin thioesterase OTUB1 (Homo sapiens)	BDBM50591324 (CHEMBL5185273) Show SMILES CN1CC[C@H](C1)Oc1ccc(F)c(-c2nc3c(o2)C(=O)c2ccccc2C3=O)c1Cl |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Caspase-4 (Homo sapiens (Human))	BDBM50160974 (CHEMBL366927 | [3-(2-{5-tert-Butyl-3-[(4-methyl-fu...) Show SMILES CCCCCC[NH+](C)CC(=O)C(CC(O)=O)NC(=O)C(CC)n1cc(nc(NCc2nonc2C)c1=O)C(C)(C)C Show InChI InChI=1S/C28H45N7O6/c1-8-10-11-12-13-34(7)16-22(36)19(14-24(37)38)30-26(39)21(9-2)35-17-23(28(4,5)6)31-25(27(35)40)29-15-20-18(3)32-41-33-20/h17,19,21H,8-16H2,1-7H3,(H,29,31)(H,30,39)(H,37,38)/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory concentration against human caspase-4 in neuronal precursor (NT2) cells				Bioorg Med Chem Lett 15: 1173-80 (2005) Article DOI: 10.1016/j.bmcl.2004.12.006 BindingDB Entry DOI: 10.7270/Q2D50MGS
					More data for this Ligand-Target Pair
Ubiquitin thioesterase OTUB1 (Homo sapiens)	BDBM50591323 (CHEMBL5173239) Show SMILES CN1CC[C@H](C1)Oc1ccc(Cl)c(-c2nc3c(o2)C(=O)c2ccccc2C3=O)c1F |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Caspase-4 (Homo sapiens (Human))	BDBM50160957 (CHEMBL179503 | [3-(2-{5-tert-Butyl-3-[(4-methyl-fu...) Show SMILES CCCCC[NH+](C)CC(=O)C(CC(O)=O)NC(=O)C(CC)n1cc(nc(NCc2nonc2C)c1=O)C(C)(C)C Show InChI InChI=1S/C27H43N7O6/c1-8-10-11-12-33(7)15-21(35)18(13-23(36)37)29-25(38)20(9-2)34-16-22(27(4,5)6)30-24(26(34)39)28-14-19-17(3)31-40-32-19/h16,18,20H,8-15H2,1-7H3,(H,28,30)(H,29,38)(H,36,37)/p+1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory concentration against human caspase-4 in neuronal precursor (NT2) cells				Bioorg Med Chem Lett 15: 1173-80 (2005) Article DOI: 10.1016/j.bmcl.2004.12.006 BindingDB Entry DOI: 10.7270/Q2D50MGS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517033 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517030 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccc(C)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516997 ((R)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...) Show SMILES CC[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517021 ((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- hydroxypr...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517038 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517002 ((R)—N-(3-fluoro-4-((3-((1-hydroxypropan-2-yl)amino...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516967 (N-(3-fluoro-4-((3- (((1s,3s)-3- (hydroxymethyl)cyc...) Show SMILES OC[C@H]1CC(C1)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r,wU:2.1,(-12.34,2.12,;-11.94,.63,;-10.45,.23,;-9.12,1,;-8.35,-.33,;-9.68,-1.1,;-6.86,-.73,;-6.46,-2.22,;-7.37,-3.47,;-6.46,-4.71,;-5,-4.23,;-3.67,-5,;-2.33,-4.23,;-2.33,-2.69,;-3.67,-1.93,;-3.67,-.38,;-2.33,.38,;-1,-.38,;.34,.38,;.34,1.93,;1.67,2.69,;3,1.93,;3,.38,;4.34,2.69,;4.34,4.23,;5.67,5,;7,4.23,;7,2.69,;8.34,1.93,;8.34,.38,;9.67,-.38,;11.01,.38,;12.34,-.38,;11.01,1.93,;9.67,2.69,;5.67,1.93,;5.67,.38,;-1,2.69,;-2.33,1.93,;-3.67,2.69,;-5,-2.69,)| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517047 ((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C)cc(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516975 (N-(4-((3-((1,3- dihydroxypropan-2- yl)amino)-1H- p...) Show SMILES OCC(CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517009 (N-(3-fluoro-4-((3- (((2R,3R)-3- hydroxybutan-2- yl...) Show SMILES C[C@@H](O)[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517007 (N-(3-fluoro-4-((3-((2- hydroxy-2- methylpropyl)ami...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(NCC(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517051 ((R)-5-bromo-N-(3- fluoro-4-((3-((1- hydroxypropan-...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(Br)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517034 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nccn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517032 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4c(C)ccn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517014 ((R)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517006 ((S)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...) Show SMILES C[C@H](O)CNc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516981 (N-(4-((3-((4,4-difluoro-1- hydroxybutan-2- yl)amin...) Show SMILES OCC(CC(F)F)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Ubiquitin thioesterase OTUB1 (Homo sapiens)	BDBM50591321 (CHEMBL5172138) Show SMILES O=C1c2nc(oc2C(=O)c2ccccc12)-c1cccnc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES CCn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@@H](C)COC)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516979 (N-(3-fluoro-4-((3-((1- hydroxy-4-methoxybutan- 2-y...) Show SMILES COCCC(CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)c(F)c5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517049 ((R)-5-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccc(F)cc5)c4=O)C4CC4)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517099 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(C)cn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516998 ((S)-N-(3-fluoro-4-((3- ((1-hydroxybutan-2- yl)amin...) Show SMILES CC[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517028 ((S)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517090 ((R)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccc(C)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516966 (N-(3-fluoro-4-((3- (((1r,3r)-3- (hydroxymethyl)cyc...) Show SMILES OC[C@H]1CC(C1)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r,wD:2.1,(-12.34,2.12,;-11.94,.63,;-10.45,.23,;-9.68,-1.1,;-8.35,-.33,;-9.12,1,;-6.86,-.73,;-6.46,-2.22,;-7.37,-3.47,;-6.46,-4.71,;-5,-4.23,;-3.67,-5,;-2.33,-4.23,;-2.33,-2.69,;-3.67,-1.93,;-3.67,-.38,;-2.33,.38,;-1,-.38,;.34,.38,;.34,1.93,;1.67,2.69,;3,1.93,;3,.38,;4.34,2.69,;4.34,4.23,;5.67,5,;7,4.23,;7,2.69,;8.34,1.93,;8.34,.38,;9.67,-.38,;11.01,.38,;12.34,-.38,;11.01,1.93,;9.67,2.69,;5.67,1.93,;5.67,.38,;-1,2.69,;-2.33,1.93,;-3.67,2.69,;-5,-2.69,)| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516964 (N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...) Show SMILES CC(Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12)C(C)(C)O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517080 ((S)-1- (cyclopropylmethyl)-N- (3-fluoro-4-((3-((1-...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517003 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)(me...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N(C)[C@H](C)CO)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516985 ((R)-N-(3-fluoro-4-((3-((1- hydroxybutan-2- yl)amin...) Show SMILES CC[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517076 ((R)—N-(3-fluoro-4-((3-((1-methoxypropan-2-yl)amino...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517011 ((S)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@@H](C)C(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517040 ((R)-1-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517037 ((R)-N-(3-fluoro-4-((3- ((1-hydroxypropan-2- yl)ami...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4nn(C(C)C)c(=S)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516964 (N-(3-fluoro-4-((3-((3- hydroxy-3-methylbutan-2- yl...) Show SMILES CC(Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12)C(C)(C)O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516955 ((S)-N-(3-fluoro-4-((3- ((1-methoxypropan-2- yl)ami...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517082 ((S)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...) Show SMILES COC[C@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516991 (N-(3-fluoro-4-((3-((1- hydroxy-2- (hydroxymethyl)b...) Show SMILES CCC(CO)(CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM516986 ((S)-N-(3-fluoro-4-((3-((1- hydroxybutan-2- yl)amin...) Show SMILES CC[C@@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4ccnn(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517109 ((R)-1-(cyclopropylmethyl)-N-(3-fluoro-4-((3-((1-me...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(CC5CC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517010 ((R)-N-(3-fluoro-4-((3- ((3-hydroxy-3- methylbutan-...) Show SMILES CC(C)n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@H](C)C(C)(C)O)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517005 ((R)-N-(3-fluoro-4-((3- ((2- hydroxypropyl)amino)- ...) Show SMILES C[C@@H](O)CNc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517091 ((R)-1-cyclobutyl-N-(3- fluoro-4-((3-((1- methoxypr...) Show SMILES COC[C@@H](C)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C5CCC5)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517127 (N-(3-fluoro-4-((3- (methylamino)-1H- pyrazolo[3,4-...) Show SMILES CNc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517035 ((R)-6-cyclopropyl-N-(3- fluoro-4-((3-((1- hydroxyp...) Show SMILES C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cc(nn(-c5ccc(F)cc5)c4=O)C4CC4)cc3F)c12 |r| Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The affinity of compound binding to wild type and mutant human MET kinases is measured using Invitrogen's LanthaScreen™ Eu Kinase Binding technol...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BZ6962
					More data for this Ligand-Target Pair

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