Compile Data Set for Download or QSAR

Found 53 hits of ic50 data for polymerid = 10602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431244 (CHEMBL2333064) Show SMILES CCCCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OC)c1=O Show InChI InChI=1S/C15H22FN3O5/c1-3-4-5-6-7-8-9-17-13(21)18-10-11(16)12(20)19(14(18)22)15(23)24-2/h10H,3-9H2,1-2H3,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431246 (CHEMBL2333062 | US9428465, 32) Show SMILES CCCCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C14H20F3N3O3/c1-2-3-4-5-6-7-8-18-12(22)20-9-10(14(15,16)17)11(21)19-13(20)23/h9H,2-8H2,1H3,(H,18,22)(H,19,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431246 (CHEMBL2333062 | US9428465, 32) Show SMILES CCCCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C14H20F3N3O3/c1-2-3-4-5-6-7-8-18-12(22)20-9-10(14(15,16)17)11(21)19-13(20)23/h9H,2-8H2,1H3,(H,18,22)(H,19,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431255 (CHEMBL2333053) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OC)c1=O Show InChI InChI=1S/C13H18FN3O5/c1-3-4-5-6-7-15-11(19)16-8-9(14)10(18)17(12(16)20)13(21)22-2/h8H,3-7H2,1-2H3,(H,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM319796 (US10174015, Compound 9) Show SMILES Clc1cccc(CCCCCC(=O)N2CCOC2=O)c1 Show InChI InChI=1S/C15H18ClNO3/c16-13-7-4-6-12(11-13)5-2-1-3-8-14(18)17-9-10-20-15(17)19/h4,6-7,11H,1-3,5,8-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431271 (CHEMBL2333033 | US9428465, 4) Show SMILES CCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C12H16F3N3O3/c1-2-3-4-5-6-16-10(20)18-7-8(12(13,14)15)9(19)17-11(18)21/h7H,2-6H2,1H3,(H,16,20)(H,17,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431271 (CHEMBL2333033 | US9428465, 4) Show SMILES CCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C12H16F3N3O3/c1-2-3-4-5-6-16-10(20)18-7-8(12(13,14)15)9(19)17-11(18)21/h7H,2-6H2,1H3,(H,16,20)(H,17,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat acid ceramidase				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01561 BindingDB Entry DOI: 10.7270/Q2G73JC2
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431254 (CHEMBL2333054) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OCC)c1=O Show InChI InChI=1S/C14H20FN3O5/c1-3-5-6-7-8-16-12(20)17-9-10(15)11(19)18(13(17)21)14(22)23-4-2/h9H,3-8H2,1-2H3,(H,16,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431271 (CHEMBL2333033 | US9428465, 4) Show SMILES CCCCCCNC(=O)n1cc(c(=O)[nH]c1=O)C(F)(F)F Show InChI InChI=1S/C12H16F3N3O3/c1-2-3-4-5-6-16-10(20)18-7-8(12(13,14)15)9(19)17-11(18)21/h7H,2-6H2,1H3,(H,16,20)(H,17,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431260 (CHEMBL2333048) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C)c1=O Show InChI InChI=1S/C12H18FN3O3/c1-3-4-5-6-7-14-11(18)16-8-9(13)10(17)15(2)12(16)19/h8H,3-7H2,1-2H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431253 (CHEMBL2333055) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OCC(C)C)c1=O Show InChI InChI=1S/C16H24FN3O5/c1-4-5-6-7-8-18-14(22)19-9-12(17)13(21)20(15(19)23)16(24)25-10-11(2)3/h9,11H,4-8,10H2,1-3H3,(H,18,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat acid ceramidase				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01561 BindingDB Entry DOI: 10.7270/Q2G73JC2
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431253 (CHEMBL2333055) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)OCC(C)C)c1=O Show InChI InChI=1S/C16H24FN3O5/c1-4-5-6-7-8-18-14(22)19-9-12(17)13(21)20(15(19)23)16(24)25-10-11(2)3/h9,11H,4-8,10H2,1-3H3,(H,18,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431258 (CHEMBL2333050) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(CC)c1=O Show InChI InChI=1S/C13H20FN3O3/c1-3-5-6-7-8-15-12(19)17-9-10(14)11(18)16(4-2)13(17)20/h9H,3-8H2,1-2H3,(H,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431252 (CHEMBL2333056) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)c2ccccc2)c1=O Show InChI InChI=1S/C18H20FN3O4/c1-2-3-4-8-11-20-17(25)21-12-14(19)16(24)22(18(21)26)15(23)13-9-6-5-7-10-13/h5-7,9-10,12H,2-4,8,11H2,1H3,(H,20,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431256 (CHEMBL2333052) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(C(=O)C(C)C)c1=O Show InChI InChI=1S/C15H22FN3O4/c1-4-5-6-7-8-17-14(22)18-9-11(16)13(21)19(15(18)23)12(20)10(2)3/h9-10H,4-8H2,1-3H3,(H,17,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431275 (CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431275 (CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat acid ceramidase				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01561 BindingDB Entry DOI: 10.7270/Q2G73JC2
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM241944 (US9428465, 16) Show SMILES CCCCCCNC(=O)n1cc(C)c(=O)n(CC2CC2)c1=O Show InChI InChI=1S/C16H25N3O3/c1-3-4-5-6-9-17-15(21)19-10-12(2)14(20)18(16(19)22)11-13-7-8-13/h10,13H,3-9,11H2,1-2H3,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431248 (CHEMBL2333060) Show SMILES CCCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O Show InChI InChI=1S/C13H20FN3O3/c1-2-3-4-5-6-7-8-15-12(19)17-9-10(14)11(18)16-13(17)20/h9H,2-8H2,1H3,(H,15,19)(H,16,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431262 (CHEMBL2333042 | US9428465, 5) Show SMILES CCCCCCNC(=O)n1cc(Br)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16BrN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431262 (CHEMBL2333042 | US9428465, 5) Show SMILES CCCCCCNC(=O)n1cc(Br)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16BrN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431259 (CHEMBL2333049) Show SMILES CCCCCCNC(=O)n1ccc(=O)n(C)c1=O Show InChI InChI=1S/C12H19N3O3/c1-3-4-5-6-8-13-11(17)15-9-7-10(16)14(2)12(15)18/h7,9H,3-6,8H2,1-2H3,(H,13,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM319818 (US10174015, Compound 31) Show SMILES Oc1ccc(CCCCCC(=O)N2CCOC2=O)cc1 Show InChI InChI=1S/C15H19NO4/c17-13-8-6-12(7-9-13)4-2-1-3-5-14(18)16-10-11-20-15(16)19/h6-9,17H,1-5,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431257 (CHEMBL2333051) Show SMILES CCCCCCNC(=O)n1cc(F)c(=O)n(CC2CC2)c1=O Show InChI InChI=1S/C15H22FN3O3/c1-2-3-4-5-8-17-14(21)19-10-12(16)13(20)18(15(19)22)9-11-6-7-11/h10-11H,2-9H2,1H3,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431272 (CHEMBL2333032 | US9428465, 3) Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat acid ceramidase				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01561 BindingDB Entry DOI: 10.7270/Q2G73JC2
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431272 (CHEMBL2333032 | US9428465, 3) Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431272 (CHEMBL2333032 | US9428465, 3) Show SMILES CCCCCCNC(=O)n1cc(Cl)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16ClN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50456926 (CHEMBL4213415) Show SMILES O=C(N1CCOC1=O)c1ccc(OC2CCCCC2)cc1 Show InChI InChI=1S/C16H19NO4/c18-15(17-10-11-20-16(17)19)12-6-8-14(9-7-12)21-13-4-2-1-3-5-13/h6-9,13H,1-5,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431263 (CHEMBL2333041 | US9428465, 8) Show SMILES CCCCCCNC(=O)n1cc(I)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16IN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431263 (CHEMBL2333041 | US9428465, 8) Show SMILES CCCCCCNC(=O)n1cc(I)c(=O)[nH]c1=O Show InChI InChI=1S/C11H16IN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	147	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431264 (CHEMBL2333040 | US9428465, 14) Show SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H21N3O3/c1-2-3-4-8-11-18-16(22)20-12-14(15(21)19-17(20)23)13-9-6-5-7-10-13/h5-7,9-10,12H,2-4,8,11H2,1H3,(H,18,22)(H,19,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	177	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431264 (CHEMBL2333040 | US9428465, 14) Show SMILES CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C17H21N3O3/c1-2-3-4-8-11-18-16(22)20-12-14(15(21)19-17(20)23)13-9-6-5-7-10-13/h5-7,9-10,12H,2-4,8,11H2,1H3,(H,18,22)(H,19,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM319789 (US10174015, Compound 2) Show SMILES O=C(CCCCCc1ccccc1)N1CCOC1=O Show InChI InChI=1S/C15H19NO3/c17-14(16-11-12-19-15(16)18)10-6-2-5-9-13-7-3-1-4-8-13/h1,3-4,7-8H,2,5-6,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431247 (CHEMBL2333061) Show SMILES CCCCCCCCNC(=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C13H21N3O3/c1-2-3-4-5-6-7-9-14-12(18)16-10-8-11(17)15-13(16)19/h8,10H,2-7,9H2,1H3,(H,14,18)(H,15,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431249 (CHEMBL2333059) Show SMILES CCCCCCCNC(=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O3/c1-2-3-4-5-6-8-13-11(17)15-9-7-10(16)14-12(15)18/h7,9H,2-6,8H2,1H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431269 (CHEMBL2333035 | US9428465, 7) Show SMILES CCCCCCNC(=O)n1cc(CO)c(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O4/c1-2-3-4-5-6-13-11(18)15-7-9(8-16)10(17)14-12(15)19/h7,16H,2-6,8H2,1H3,(H,13,18)(H,14,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431269 (CHEMBL2333035 | US9428465, 7) Show SMILES CCCCCCNC(=O)n1cc(CO)c(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O4/c1-2-3-4-5-6-13-11(18)15-7-9(8-16)10(17)14-12(15)19/h7,16H,2-6,8H2,1H3,(H,13,18)(H,14,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	420	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431274 (CHEMBL2333065) Show SMILES CCCCCCNC(=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C11H17N3O3/c1-2-3-4-5-7-12-10(16)14-8-6-9(15)13-11(14)17/h6,8H,2-5,7H2,1H3,(H,12,16)(H,13,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	426	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431245 (CHEMBL2333063) Show SMILES CCCCCCCCCNC(=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C14H23N3O3/c1-2-3-4-5-6-7-8-10-15-13(19)17-11-9-12(18)16-14(17)20/h9,11H,2-8,10H2,1H3,(H,15,19)(H,16,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	464	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431270 (CHEMBL2333034) Show SMILES CCCCCCNC(=O)n1cc(CC)c(=O)[nH]c1=O Show InChI InChI=1S/C13H21N3O3/c1-3-5-6-7-8-14-12(18)16-9-10(4-2)11(17)15-13(16)19/h9H,3-8H2,1-2H3,(H,14,18)(H,15,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	733	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431266 (CHEMBL2333038 | US9428465, 12) Show SMILES CCCCCCNC(=O)n1cc(N2CCOCC2)c(=O)[nH]c1=O Show InChI InChI=1S/C15H24N4O4/c1-2-3-4-5-6-16-14(21)19-11-12(13(20)17-15(19)22)18-7-9-23-10-8-18/h11H,2-10H2,1H3,(H,16,21)(H,17,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	875	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431266 (CHEMBL2333038 | US9428465, 12) Show SMILES CCCCCCNC(=O)n1cc(N2CCOCC2)c(=O)[nH]c1=O Show InChI InChI=1S/C15H24N4O4/c1-2-3-4-5-6-16-14(21)19-11-12(13(20)17-15(19)22)18-7-9-23-10-8-18/h11H,2-10H2,1H3,(H,16,21)(H,17,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	880	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431268 (CHEMBL2333036 | US9428465, 9) Show SMILES CCCCCCNC(=O)n1cc(OC)c(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O4/c1-3-4-5-6-7-13-11(17)15-8-9(19-2)10(16)14-12(15)18/h8H,3-7H2,1-2H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431268 (CHEMBL2333036 | US9428465, 9) Show SMILES CCCCCCNC(=O)n1cc(OC)c(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O4/c1-3-4-5-6-7-13-11(17)15-8-9(19-2)10(16)14-12(15)18/h8H,3-7H2,1-2H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431265 (CHEMBL2333039 | US9428465, 13) Show SMILES CCCCCCNC(=O)n1cc(N2CCN(C)CC2)c(=O)[nH]c1=O Show InChI InChI=1S/C16H27N5O3/c1-3-4-5-6-7-17-15(23)21-12-13(14(22)18-16(21)24)20-10-8-19(2)9-11-20/h12H,3-11H2,1-2H3,(H,17,23)(H,18,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431265 (CHEMBL2333039 | US9428465, 13) Show SMILES CCCCCCNC(=O)n1cc(N2CCN(C)CC2)c(=O)[nH]c1=O Show InChI InChI=1S/C16H27N5O3/c1-3-4-5-6-7-17-15(23)21-12-13(14(22)18-16(21)24)20-10-8-19(2)9-11-20/h12H,3-11H2,1-2H3,(H,17,23)(H,18,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431273 (CHEMBL2333031) Show SMILES CCCCCCNC(=O)n1cc(C)c(=O)[nH]c1=O Show InChI InChI=1S/C12H19N3O3/c1-3-4-5-6-7-13-11(17)15-8-9(2)10(16)14-12(15)18/h8H,3-7H2,1-2H3,(H,13,17)(H,14,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431250 (CHEMBL2333058) Show SMILES CCCCCNC(=O)n1ccc(=O)[nH]c1=O Show InChI InChI=1S/C10H15N3O3/c1-2-3-4-6-11-9(15)13-7-5-8(14)12-10(13)16/h5,7H,2-4,6H2,1H3,(H,11,15)(H,12,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431261 (CHEMBL2333044 | US9428465, 11) Show SMILES CCCCCCNC(=O)n1cc(NC)c(=O)[nH]c1=O Show InChI InChI=1S/C12H20N4O3/c1-3-4-5-6-7-14-11(18)16-8-9(13-2)10(17)15-12(16)19/h8,13H,3-7H2,1-2H3,(H,14,18)(H,15,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...				J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5
					More data for this Ligand-Target Pair
Acid ceramidase (Rattus norvegicus (Rat))	BDBM50431261 (CHEMBL2333044 | US9428465, 11) Show SMILES CCCCCCNC(=O)n1cc(NC)c(=O)[nH]c1=O Show InChI InChI=1S/C12H20N4O3/c1-3-4-5-6-7-14-11(18)16-8-9(13-2)10(17)15-12(16)19/h8,13H,3-7H2,1-2H3,(H,14,18)(H,15,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	4.5	n/a
Fondazione Istituto Italiano Di Technologia US Patent					Assay Description r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...				US Patent US9428465 (2016) BindingDB Entry DOI: 10.7270/Q26972GB
					More data for this Ligand-Target Pair

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