Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247254 (US9447029, 1-7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247253 (US9447029, 1-6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247250 (US9447029, 1-1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247256 (US9447029, 1-15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247257 (US9447029, 1-18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247260 (US9447029, 1-32) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247255 (US9447029, 1-14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247259 (US9447029, 1-29) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50171290 (5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi-Synthelabo Recherche Curated by PDSP Ki Database | J Pharmacol Exp Ther 310: 905-14 (2004) Article DOI: 10.1124/jpet.104.067884 BindingDB Entry DOI: 10.7270/Q2RR1WTX | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247264 (US9447029, 4-1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM247263 (US9447029, 3-3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NEWRON PHARMACEUTICALS S.P.A. US Patent | Assay Description Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa... | US Patent US9447029 (2016) BindingDB Entry DOI: 10.7270/Q26T0KJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM50187673 (5-(3,3,6-trimethyl-indan-5-yloxy)-furan-2-carboxyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research & Development Curated by ChEMBL | Assay Description Binding affinity to verapamil site of N type calcium channel | J Med Chem 49: 3362-7 (2006) Article DOI: 10.1021/jm060012g BindingDB Entry DOI: 10.7270/Q2F76C54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human)) | BDBM21280 (5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)met...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi Recherche Curated by PDSP Ki Database | J Pharmacol Exp Ther 284: 644-50 (1998) BindingDB Entry DOI: 10.7270/Q2D50KHT | ||||||||||||
More data for this Ligand-Target Pair |