Compile Data Set for Download or QSAR

Found 1278 hits of ic50 for UniProtKB: P21396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM174835 (US9114126, 2027BA1) Show SMILES COc1cc(O)c2c(c1)oc1ccc(O)c(OC)c1c2=O Show InChI InChI=1S/C15H12O6/c1-19-7-5-9(17)12-11(6-7)21-10-4-3-8(16)15(20-2)13(10)14(12)18/h3-6,16-17H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars		n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
General Hospital of PLA Curated by ChEMBL					Assay Description Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assay				Bioorg Med Chem Lett 22: 3343-8 (2012) Article DOI: 10.1016/j.bmcl.2012.02.090 BindingDB Entry DOI: 10.7270/Q2JW8FWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro Inhibitory activity of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT (serotonin)				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50381960 (CHEMBL2022927) Show SMILES CN(CC#C)Cc1cc2cc(OCc3ccccc3)ccc2[nH]1 Show InChI InChI=1S/C20H20N2O/c1-3-11-22(2)14-18-12-17-13-19(9-10-20(17)21-18)23-15-16-7-5-4-6-8-16/h1,4-10,12-13,21H,11,14-15H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Qu�mica Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...				Eur J Med Chem 52: 251-62 (2012) Article DOI: 10.1016/j.ejmech.2012.03.022 BindingDB Entry DOI: 10.7270/Q25H7H97
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50367064 (CHEMBL1204338) Show SMILES CN1C(Cc2ccccc2N=C1C)c1ccccc1 |c:11| Show InChI InChI=1S/C17H18N2/c1-13-18-16-11-7-6-10-15(16)12-17(19(13)2)14-8-4-3-5-9-14/h3-11,17H,12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase A.				J Med Chem 25: 340-6 (1982) BindingDB Entry DOI: 10.7270/Q2862H1K
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) Show SMILES C#CCN[C@@H]1CCc2ccccc12 |r| Show InChI InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL					Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting				J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049682 (2-Methoxy-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10...) Show SMILES COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnc(C)o1 Show InChI InChI=1S/C17H12N2O5S/c1-9-18-19-17(24-9)10-3-5-12-15(7-10)25(21,22)14-6-4-11(23-2)8-13(14)16(12)20/h3-8H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50179019 (3-benzyl-N-(2-morpholinoethyl)quinoxalin-2-amine |...) Show SMILES C(CN1CCOCC1)Nc1nc2ccccc2nc1Cc1ccccc1 Show InChI InChI=1S/C21H24N4O/c1-2-6-17(7-3-1)16-20-21(22-10-11-25-12-14-26-15-13-25)24-19-9-5-4-8-18(19)23-20/h1-9H,10-16H2,(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Alexandria Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondria MAOA				Bioorg Med Chem Lett 16: 1753-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.088 BindingDB Entry DOI: 10.7270/Q2DZ07V3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50075965 (CHEMBL3415613) Show SMILES OC(=O)C([O-])=O.C[NH+](CC#C)CC(=C)c1cccc(COc2ccccc2)c1 Show InChI InChI=1S/C20H21NO/c1-4-13-21(3)15-17(2)19-10-8-9-18(14-19)16-22-20-11-6-5-7-12-20/h1,5-12,14H,2,13,15-16H2,3H3/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL					Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting				J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50179021 (3-(4-chlorobenzyl)-N-(2-morpholinoethyl)quinoxalin...) Show SMILES Clc1ccc(Cc2nc3ccccc3nc2NCCN2CCOCC2)cc1 Show InChI InChI=1S/C21H23ClN4O/c22-17-7-5-16(6-8-17)15-20-21(23-9-10-26-11-13-27-14-12-26)25-19-4-2-1-3-18(19)24-20/h1-8H,9-15H2,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alexandria Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondria MAOA				Bioorg Med Chem Lett 16: 1753-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.088 BindingDB Entry DOI: 10.7270/Q2DZ07V3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049686 (2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...) Show SMILES COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 Show InChI InChI=1S/C16H12N4O4S/c1-20-18-16(17-19-20)9-3-5-11-14(7-9)25(22,23)13-6-4-10(24-2)8-12(13)15(11)21/h3-8H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049704 (2-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,11-dioxa-dib...) Show SMILES Cc1nnc(o1)-c1ccc2c(OOc3ccccc3C2=O)c1 Show InChI InChI=1S/C16H10N2O4/c1-9-17-18-16(20-9)10-6-7-12-14(8-10)22-21-13-5-3-2-4-11(13)15(12)19/h2-8H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049701 (3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,10-dioxo-10H...) Show SMILES Cc1nnc(o1)-c1ccc2C(=O)c3ccccc3S(=O)(=O)c2c1 Show InChI InChI=1S/C16H10N2O4S/c1-9-17-18-16(22-9)10-6-7-12-14(8-10)23(20,21)13-5-3-2-4-11(13)15(12)19/h2-8H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50059304 (9,10,10-Trioxo-7-propoxy-9,10-dihydro-10lambda*6*-...) Show SMILES CCCOc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)C(=O)NC Show InChI InChI=1S/C18H17NO5S/c1-3-8-24-12-5-7-15-14(10-12)17(20)13-6-4-11(18(21)19-2)9-16(13)25(15,22)23/h4-7,9-10H,3,8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Monoamine oxidase A (MAO A) in rat brain.				J Med Chem 40: 2466-73 (1997) Article DOI: 10.1021/jm9608063 BindingDB Entry DOI: 10.7270/Q2RN38JM
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50075969 (CHEMBL3415617) Show SMILES OC(=O)C([O-])=O.C[NH+](CC#C)CC(=C)c1cccc(OCc2cccc(F)c2)c1 Show InChI InChI=1S/C20H20FNO/c1-4-11-22(3)14-16(2)18-8-6-10-20(13-18)23-15-17-7-5-9-19(21)12-17/h1,5-10,12-13H,2,11,14-15H2,3H3/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL					Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting				J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049703 (6-(2-Methyl-2H-tetrazol-5-yl)-10,10-dioxo-2-propox...) Show SMILES CCCOc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 Show InChI InChI=1S/C18H16N4O4S/c1-3-8-26-12-5-7-15-14(10-12)17(23)13-6-4-11(9-16(13)27(15,24)25)18-19-21-22(2)20-18/h4-7,9-10H,3,8H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049666 (5-(10,10-Dioxo-10H-10lambda*6*-phenoxathiin-2-yl)-...) Show SMILES Cn1nnc(n1)-c1ccc2Oc3ccccc3S(=O)(=O)c2c1 Show InChI InChI=1S/C14H10N4O3S/c1-18-16-14(15-17-18)9-6-7-11-13(8-9)22(19,20)12-5-3-2-4-10(12)21-11/h2-8H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049671 (2-Methyl-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10-...) Show SMILES Cc1nnc(o1)-c1ccc2C(=O)c3cc(C)ccc3S(=O)(=O)c2c1 Show InChI InChI=1S/C17H12N2O4S/c1-9-3-6-14-13(7-9)16(20)12-5-4-11(8-15(12)24(14,21)22)17-19-18-10(2)23-17/h3-8H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50179017 (1-(3-(4-chlorobenzyl)quinoxalin-2-yl)hydrazine | C...) Show SMILES NNc1nc2ccccc2nc1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C15H13ClN4/c16-11-7-5-10(6-8-11)9-14-15(20-17)19-13-4-2-1-3-12(13)18-14/h1-8H,9,17H2,(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Alexandria Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondria MAOA				Bioorg Med Chem Lett 16: 1753-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.088 BindingDB Entry DOI: 10.7270/Q2DZ07V3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	CHEMBL5271774 Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50088564 (CHEMBL3577041) Show SMILES COC(=O)[C@@H](NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1)C(C)C |r| Show InChI InChI=1S/C23H25N3O6/c1-13(2)19(23(31)32-4)26-21(29)15-9-11-16(12-10-15)25-22(30)20(28)17-7-5-6-8-18(17)24-14(3)27/h5-13,19H,1-4H3,(H,24,27)(H,25,30)(H,26,29)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition				Bioorg Med Chem Lett 25: 70-4 (2015) Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition				Bioorg Med Chem Lett 25: 70-4 (2015) Article DOI: 10.1016/j.bmcl.2014.11.007 BindingDB Entry DOI: 10.7270/Q24F1SGH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50179020 (2-(3-benzylquinoxalin-2-ylamino)ethanol | CHEMBL20...) Show SMILES OCCNc1nc2ccccc2nc1Cc1ccccc1 Show InChI InChI=1S/C17H17N3O/c21-11-10-18-17-16(12-13-6-2-1-3-7-13)19-14-8-4-5-9-15(14)20-17/h1-9,21H,10-12H2,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Alexandria Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondria MAOA				Bioorg Med Chem Lett 16: 1753-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.088 BindingDB Entry DOI: 10.7270/Q2DZ07V3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C |r| Show InChI InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50224952 (CHEMBL441014) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC=C=C Show InChI InChI=1S/C14H17Cl2NO/c1-3-4-8-17(2)9-5-10-18-14-7-6-12(15)11-13(14)16/h4,6-7,11H,1,5,8-10H2,2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of Monoamine oxidase at rat hyphalamic mitochondrial 5-HT by displacing 2.5 uM of [14C]5-HT.				J Med Chem 26: 1036-42 (1983) BindingDB Entry DOI: 10.7270/Q2K076FV
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50288969 (4-(7-Bromo-5-methoxy-benzofuran-2-yl)-piperidine |...) Show SMILES COc1cc(Br)c2oc(cc2c1)C1CCNCC1 Show InChI InChI=1S/C14H16BrNO2/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11/h6-9,16H,2-5H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225462 (CHEMBL554775) Show SMILES Cl.COc1cccc(c1)C(\CN)=C/F Show InChI InChI=1S/C10H12FNO/c1-13-10-4-2-3-8(5-10)9(6-11)7-12/h2-6H,7,12H2,1H3/b9-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049687 (2-Isopropyl-6-(2-methyl-2H-tetrazol-5-yl)-10,10-di...) Show SMILES CC(C)c1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 Show InChI InChI=1S/C18H16N4O3S/c1-10(2)11-5-7-15-14(8-11)17(23)13-6-4-12(9-16(13)26(15,24)25)18-19-21-22(3)20-18/h4-10H,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50282522 (4-Chloro-benzenesulfonic acid 3,4-dimethyl-2-oxo-2...) Show SMILES Cc1c(C)c(=O)oc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C17H13ClO5S/c1-10-11(2)17(19)22-16-9-13(5-8-15(10)16)23-24(20,21)14-6-3-12(18)4-7-14/h3-9H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50359391 (CHEMBL1929421) Show SMILES CN(CC#C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C Show InChI InChI=1S/C29H37N3O/c1-4-16-30(2)23-27-20-26-21-28(12-13-29(26)31(27)3)33-19-8-11-24-14-17-32(18-15-24)22-25-9-6-5-7-10-25/h1,5-7,9-10,12-13,20-21,24H,8,11,14-19,22-23H2,2-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation counting				J Med Chem 54: 8251-70 (2011) Article DOI: 10.1021/jm200853t BindingDB Entry DOI: 10.7270/Q20P10G5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50359391 (CHEMBL1929421) Show SMILES CN(CC#C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C Show InChI InChI=1S/C29H37N3O/c1-4-16-30(2)23-27-20-26-21-28(12-13-29(26)31(27)3)33-19-8-11-24-14-17-32(18-15-24)22-25-9-6-5-7-10-25/h1,5-7,9-10,12-13,20-21,24H,8,11,14-19,22-23H2,2-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondrial MAOA [14C]-5-HT as substrate preincubated for 30 mins followed by substrate addition by liquid scintillation co...				Eur J Med Chem 176: 228-247 (2019) Article DOI: 10.1016/j.ejmech.2019.05.020 BindingDB Entry DOI: 10.7270/Q2KH0RNP
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50359391 (CHEMBL1929421) Show SMILES CN(CC#C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C Show InChI InChI=1S/C29H37N3O/c1-4-16-30(2)23-27-20-26-21-28(12-13-29(26)31(27)3)33-19-8-11-24-14-17-32(18-15-24)22-25-9-6-5-7-10-25/h1,5-7,9-10,12-13,20-21,24H,8,11,14-19,22-23H2,2-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondrial MAOA using [14C]-5-HT as substrate preincubated for 30 mins followed by substrate addition measured after 10 mi...				Eur J Med Chem 158: 463-477 (2018) Article DOI: 10.1016/j.ejmech.2018.09.031 BindingDB Entry DOI: 10.7270/Q26H4M3Z
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50059303 (7-Isopropyl-9,10,10-trioxo-9,10-dihydro-10lambda*6...) Show SMILES CNC(=O)c1ccc2C(=O)c3cc(ccc3S(=O)(=O)c2c1)C(C)C Show InChI InChI=1S/C18H17NO4S/c1-10(2)11-5-7-15-14(8-11)17(20)13-6-4-12(18(21)19-3)9-16(13)24(15,22)23/h4-10H,1-3H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Monoamine oxidase A (MAO A) in rat brain.				J Med Chem 40: 2466-73 (1997) Article DOI: 10.1021/jm9608063 BindingDB Entry DOI: 10.7270/Q2RN38JM
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50282520 (4-Bromo-benzenesulfonic acid 3,4-dimethyl-2-oxo-2H...) Show SMILES Cc1c(C)c(=O)oc2cc(OS(=O)(=O)c3ccc(Br)cc3)ccc12 Show InChI InChI=1S/C17H13BrO5S/c1-10-11(2)17(19)22-16-9-13(5-8-15(10)16)23-24(20,21)14-6-3-12(18)4-7-14/h3-9H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50064684 (3-Ethyl-phenoxathiine 10,10-dioxide | CHEMBL67629) Show SMILES CCc1ccc2c(Oc3ccccc3S2(=O)=O)c1 Show InChI InChI=1S/C14H12O3S/c1-2-10-7-8-14-12(9-10)17-11-5-3-4-6-13(11)18(14,15)16/h3-9H,2H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
The Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A.				J Med Chem 41: 2118-25 (1998) Article DOI: 10.1021/jm970862j BindingDB Entry DOI: 10.7270/Q25T3JM8
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50075994 (CHEMBL3415785) Show SMILES OC(=O)C([O-])=O.COc1ccc(OCc2cccc(c2)C(=C)C[NH+](C)CC#C)cc1 Show InChI InChI=1S/C21H23NO2/c1-5-13-22(3)15-17(2)19-8-6-7-18(14-19)16-24-21-11-9-20(23-4)10-12-21/h1,6-12,14H,2,13,15-16H2,3-4H3/p+1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL					Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting				J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50359396 (CHEMBL1929420 | US8999994, 5) Show SMILES CN(CC#C)Cc1cc2cc(OCCC3CCN(Cc4ccccc4)CC3)ccc2n1C Show InChI InChI=1S/C28H35N3O/c1-4-15-29(2)22-26-19-25-20-27(10-11-28(25)30(26)3)32-18-14-23-12-16-31(17-13-23)21-24-8-6-5-7-9-24/h1,5-11,19-20,23H,12-18,21-22H2,2-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Universitat Aut£noma de Barcelona Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation counting				J Med Chem 54: 8251-70 (2011) Article DOI: 10.1021/jm200853t BindingDB Entry DOI: 10.7270/Q20P10G5
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50427725 (CHEMBL2324222) Show SMILES CNC(=O)\C=C1\COc2c1ccc(OS(=O)(=O)c1ccc(OC)cc1)c2C Show InChI InChI=1S/C19H19NO6S/c1-12-17(26-27(22,23)15-6-4-14(24-3)5-7-15)9-8-16-13(10-18(21)20-2)11-25-19(12)16/h4-10H,11H2,1-3H3,(H,20,21)/b13-10-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...				J Med Chem 56: 2651-64 (2013) Article DOI: 10.1021/jm4000769 BindingDB Entry DOI: 10.7270/Q28K7BD4
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50225466 (CHEMBL544509) Show SMILES Cl.NC\C(=C\F)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H9F4N/c11-5-8(6-15)7-2-1-3-9(4-7)10(12,13)14/h1-5H,6,15H2/b8-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rat brain mitochondrial Monoamine oxidase				J Med Chem 28: 186-93 (1985) BindingDB Entry DOI: 10.7270/Q26M3910
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50049680 (6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethoxy-10,10-di...) Show SMILES CCOc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)C1=NCCN1 |t:23| Show InChI InChI=1S/C18H16N2O4S/c1-2-24-12-4-6-15-14(10-12)17(21)13-5-3-11(18-19-7-8-20-18)9-16(13)25(15,22)23/h3-6,9-10H,2,7-8H2,1H3,(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain mitochondrial monoamine oxidase A				J Med Chem 39: 1857-63 (1996) Article DOI: 10.1021/jm950595m BindingDB Entry DOI: 10.7270/Q2TM796B
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50064680 (2-Ethyl-phenoxathiine 10,10-dioxide | CHEMBL67850) Show SMILES CCc1ccc2Oc3ccccc3S(=O)(=O)c2c1 Show InChI InChI=1S/C14H12O3S/c1-2-10-7-8-12-14(9-10)18(15,16)13-6-4-3-5-11(13)17-12/h3-9H,2H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Wellcome Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A.				J Med Chem 41: 2118-25 (1998) Article DOI: 10.1021/jm970862j BindingDB Entry DOI: 10.7270/Q25T3JM8
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM10804 ((3R)-3-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1...) Show SMILES CN(CC#C)[C@@H]1CCc2ccc(O)cc12 |r| Show InChI InChI=1S/C13H15NO/c1-3-8-14(2)13-7-5-10-4-6-11(15)9-12(10)13/h1,4,6,9,13,15H,5,7-8H2,2H3/t13-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50179018 (1-(3-benzyl-6,7-dichloroquinoxalin-2-yl)hydrazine ...) Show SMILES NNc1nc2cc(Cl)c(Cl)cc2nc1Cc1ccccc1 Show InChI InChI=1S/C15H12Cl2N4/c16-10-7-12-13(8-11(10)17)20-15(21-18)14(19-12)6-9-4-2-1-3-5-9/h1-5,7-8H,6,18H2,(H,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Alexandria Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondria MAOA				Bioorg Med Chem Lett 16: 1753-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.088 BindingDB Entry DOI: 10.7270/Q2DZ07V3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI InChI=1S/C17H19N3O2/c1-5-11-20(4)12-13-8-9-15(22-17(21)19(2)3)16-14(13)7-6-10-18-16/h1,6-10H,11-12H2,2-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Qu�mica M�dica, (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of rat MAO-A				J Med Chem 57: 10455-63 (2014) Article DOI: 10.1021/jm501501a BindingDB Entry DOI: 10.7270/Q2WS8VX3
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI InChI=1S/C17H19N3O2/c1-5-11-20(4)12-13-8-9-15(22-17(21)19(2)3)16-14(13)7-6-10-18-16/h1,6-10H,11-12H2,2-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del Estado de Morelos Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain MAOA using kynuramine as substrate preincubated for 15 mins followed by substrate addition and measured after 15 mins ...				J Nat Prod 82: 785-791 (2019) Article DOI: 10.1021/acs.jnatprod.8b00677 BindingDB Entry DOI: 10.7270/Q21N84NP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	CHEMBL5270286 Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50282507 (CHEMBL18504 | Esuprone | Ethanesulfonic acid 3,4-d...) Show SMILES CCS(=O)(=O)Oc1ccc2c(C)c(C)c(=O)oc2c1 Show InChI InChI=1S/C13H14O5S/c1-4-19(15,16)18-10-5-6-11-8(2)9(3)13(14)17-12(11)7-10/h5-7H,4H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM10807 (1-[methyl(prop-2-yn-1-yl)amino]-2,3-dihydro-1H-ind...) Show SMILES CN(CC#C)C1CCc2c1cccc2O Show InChI InChI=1S/C13H15NO/c1-3-9-14(2)12-8-7-11-10(12)5-4-6-13(11)15/h1,4-6,12,15H,7-9H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Teva Pharmaceutical Industries					Assay Description Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....				J Med Chem 45: 5260-79 (2002) Article DOI: 10.1021/jm020120c BindingDB Entry DOI: 10.7270/Q2GQ6W07
					More data for this Ligand-Target Pair

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