BindingDB PrimarySearch

Found 1411 hits of ic50 data for polymerid = 1130
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50381960 (CHEMBL2022927) Show SMILES CN(CC#C)Cc1cc2cc(OCc3ccccc3)ccc2[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0250	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Qu�mica Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...				Eur J Med Chem 52: 251-62 (2012) Article DOI: 10.1016/j.ejmech.2012.03.022 BindingDB Entry DOI: 10.7270/Q25H7H97
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282502 (7-(4-Fluoro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(F)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Dart NeuroScience, LLC Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat whole brain homogenate in presence of clorgyline				Bioorg Med Chem 23: 770-8 (2015) Article DOI: 10.1016/j.bmc.2014.12.063 BindingDB Entry DOI: 10.7270/Q2J38V8K
Dart NeuroScience, LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50240393 (3,4-dimethyl-7-methoxycoumarin \| 7-Methoxy-3,4-dim...) Show SMILES COc1ccc2c(C)c(C)c(=O)oc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282510 (7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282504 (7-(5-Cyclopropyl-isoxazol-3-ylmethoxy)-3,4-dimethy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282506 (7-(5-Isopropyl-[1,3,4]thiadiazol-2-ylmethoxy)-3,4-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282514 (3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...) Show SMILES Cc1ccc(COc2ccc3c(C)c(C)c(=O)oc3c2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50367064 (CHEMBL1204338) Show SMILES CN1C(Cc2ccccc2N=C1C)c1ccccc1 \|c:11\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of rat brain mitochondrial monoamine oxidase B				J Med Chem 25: 340-6 (1982) BindingDB Entry DOI: 10.7270/Q2862H1K
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409078 (CHEMBL325761) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rat brain mitochondrial MAOB using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production by spectrophotometry				Bioorg Med Chem 24: 5929-5940 (2016) Article DOI: 10.1016/j.bmc.2016.09.050 BindingDB Entry DOI: 10.7270/Q2FN1854
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046943 (CHEMBL3319268) Show SMILES Clc1ccc(NC(=O)c2ccc3[nH]ccc3c2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409078 (CHEMBL325761) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B				J Med Chem 44: 3195-8 (2001) BindingDB Entry DOI: 10.7270/Q2HQ417K
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409078 (CHEMBL325761) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
North-West University Curated by ChEMBL					Assay Description Competitive inhibition of rat brain MAO-B				Bioorg Med Chem Lett 23: 5498-502 (2013) Article DOI: 10.1016/j.bmcl.2013.08.071 BindingDB Entry DOI: 10.7270/Q26H4MB3
North-West University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046944 (CHEMBL3319269) Show SMILES Cn1ccc2cc(ccc12)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409078 (CHEMBL325761) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.15	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%				J Med Chem 43: 4747-58 (2000) BindingDB Entry DOI: 10.7270/Q20K29RT
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046866 (CHEMBL3319256) Show SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...				Eur J Med Chem 127: 470-492 (2017) Article DOI: 10.1016/j.ejmech.2017.01.011 BindingDB Entry DOI: 10.7270/Q2GH9M6P
NTZ Lab Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282519 (7-(3-Isopropyl-[1,2,4]oxadiazol-5-ylmethoxy)-3,4-d...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046866 (CHEMBL3319256) Show SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of rat MAO-B				Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041 BindingDB Entry DOI: 10.7270/Q2VT1WFM
NTZ Lab Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046866 (CHEMBL3319256) Show SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046950 (CHEMBL3319244) Show SMILES Clc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282521 (7-(2-Isopropyl-thiazol-4-ylmethoxy)-3,4-dimethyl-c...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046950 (CHEMBL3319244) Show SMILES Clc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...				Eur J Med Chem 127: 470-492 (2017) Article DOI: 10.1016/j.ejmech.2017.01.011 BindingDB Entry DOI: 10.7270/Q2GH9M6P
NTZ Lab Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50232425 (CHEMBL4061639) Show SMILES Cn1ncc2cc(ccc12)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...				Eur J Med Chem 127: 470-492 (2017) Article DOI: 10.1016/j.ejmech.2017.01.011 BindingDB Entry DOI: 10.7270/Q2GH9M6P
NTZ Lab Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 60 minutes preincubation periods				J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical method				Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical method				Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282508 (3,4-Dimethyl-7-(4-trifluoromethyl-benzyloxy)-chrom...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.				Bioorg Med Chem Lett 4: 1195-1198 (1994) Article DOI: 10.1016/S0960-894X(01)80328-0 BindingDB Entry DOI: 10.7270/Q2QJ7HST
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029815 (3-[5-(4-Benzyloxy-phenyl)-tetrazol-2-yl]-propionit...) Show SMILES N#CCCn1nnc(n1)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris 7 Curated by ChEMBL					Assay Description In vitro inhibitory activity against rat brain Monoamine oxidase B				J Med Chem 38: 4786-92 (1996) BindingDB Entry DOI: 10.7270/Q2T72GFV
Université Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description In vitro inhibitory activity on rat brain MAO-B.				J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 30 minutes pre-incubation periods				J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046879 (CHEMBL3317469) Show SMILES Fc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046879 (CHEMBL3317469) Show SMILES Fc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
NTZ Lab Ltd. Curated by ChEMBL					Assay Description Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...				Eur J Med Chem 127: 470-492 (2017) Article DOI: 10.1016/j.ejmech.2017.01.011 BindingDB Entry DOI: 10.7270/Q2GH9M6P
NTZ Lab Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282510 (7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.57	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409099 (CHEMBL356977) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409099 (CHEMBL356977) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.57	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%				J Med Chem 43: 4747-58 (2000) BindingDB Entry DOI: 10.7270/Q20K29RT
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282510 (7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.57	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%				J Med Chem 43: 4747-58 (2000) BindingDB Entry DOI: 10.7270/Q20K29RT
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282510 (7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B				J Med Chem 44: 3195-8 (2001) BindingDB Entry DOI: 10.7270/Q2HQ417K
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046878 (CHEMBL3319247) Show SMILES Fc1cc(NC(=O)c2ccc3[nH]ncc3c2)ccc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50046880 (CHEMBL3319246) Show SMILES Clc1cc(Cl)cc(NC(=O)c2ccc3[nH]ncc3c2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrate				J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D
University of Bonn Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) Show SMILES O=c1oc(nn1CCC#N)-c1ccc(OCc2ccccc2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris 7 Curated by ChEMBL					Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 20 minutes pre-incubation periods				J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP
Universit£ Paris 7 Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
CV Technologies Inc. Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit Monoamine oxidase B activity in rat whole brain in vitro				Bioorg Med Chem Lett 11: 2715-7 (2001) BindingDB Entry DOI: 10.7270/Q2Z60NC5
CV Technologies Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50541069 (CHEMBL4635389) Show SMILES COc1cc2cc(CN(C)CC#C)c(=O)oc2cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de Lisboa Curated by ChEMBL					Assay Description Inhibition of rat MAO B using kynuramine as substrate preincubated for 30 mins followed by substrate addition				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126880 BindingDB Entry DOI: 10.7270/Q2639T8F
Universidade de Lisboa Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409097 (CHEMBL108697) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3cccc(F)c3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B				J Med Chem 44: 3195-8 (2001) BindingDB Entry DOI: 10.7270/Q2HQ417K
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409097 (CHEMBL108697) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3cccc(F)c3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
University of Geneva Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409097 (CHEMBL108697) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3cccc(F)c3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%				J Med Chem 43: 4747-58 (2000) BindingDB Entry DOI: 10.7270/Q20K29RT
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM15579 (CHEMBL972 \| DEPRENYL \| L-Deprenyl \| N-methyl-N-[(2...) Show SMILES C[C@H](Cc1ccccc1)N(C)CC#C \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM19188 (7-(3-chlorobenzyloxy)-4-(methylamino)methyl-coumar...) Show SMILES CNCc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay in presence of human platelet rich plasma				J Med Chem 52: 6685-706 (2009) Article DOI: 10.1021/jm9010127 BindingDB Entry DOI: 10.7270/Q2DR2VJ6
Universita degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282502 (7-(4-Fluoro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(F)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B				J Med Chem 44: 3195-8 (2001) BindingDB Entry DOI: 10.7270/Q2HQ417K
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50409109 (CHEMBL108928) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B				J Med Chem 44: 3195-8 (2001) BindingDB Entry DOI: 10.7270/Q2HQ417K
Universit£ de Lausanne Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50282510 (7-(4-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one ...) Show SMILES Cc1c(C)c(=O)oc2cc(OCc3ccc(Cl)cc3)ccc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rat brain mitochondrial MAOB using kynuramine as substrate assessed as decrease in 4-hydroxyquinoline production by spectrophotometry				Bioorg Med Chem 24: 5929-5940 (2016) Article DOI: 10.1016/j.bmc.2016.09.050 BindingDB Entry DOI: 10.7270/Q2FN1854
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair

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