BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits of kd data for polymerid = 1236,50002997   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 8


(Homo sapiens (Human))
BDBM50225425
PNG
(CHEMBL440982 | di-(4-acetamido)phenyl 2-((S)-2,6-d...)
Show SMILES CC(=O)Nc1ccc(OP(=O)(Oc2ccc(NC(C)=O)cc2)C2N(Cc3ccccc23)C(=O)[C@@H](N)CCCCN)cc1
Show InChI InChI=1S/C30H36N5O6P/c1-20(36)33-23-10-14-25(15-11-23)40-42(39,41-26-16-12-24(13-17-26)34-21(2)37)30-27-8-4-3-7-22(27)19-35(30)29(38)28(32)9-5-6-18-31/h3-4,7-8,10-17,28,30H,5-6,9,18-19,31-32H2,1-2H3,(H,33,36)(H,34,37)/t28-,30?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 770n/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


J Med Chem 50: 5568-70 (2007)


Article DOI: 10.1021/jm701005a
BindingDB Entry DOI: 10.7270/Q2S75G2R
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))
BDBM50225423
PNG
(CHEMBL236781 | bis(4-acetamidophenyl) 1-((S)-2,6-d...)
Show SMILES CC(=O)Nc1ccc(OP(=O)(Oc2ccc(NC(C)=O)cc2)C2CCCN2C(=O)[C@@H](N)CCCCN)cc1
Show InChI InChI=1S/C26H36N5O6P/c1-18(32)29-20-8-12-22(13-9-20)36-38(35,37-23-14-10-21(11-15-23)30-19(2)33)25-7-5-17-31(25)26(34)24(28)6-3-4-16-27/h8-15,24-25H,3-7,16-17,27-28H2,1-2H3,(H,29,32)(H,30,33)/t24-,25?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 7.30E+3n/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


J Med Chem 50: 5568-70 (2007)


Article DOI: 10.1021/jm701005a
BindingDB Entry DOI: 10.7270/Q2S75G2R
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))
BDBM50225420
PNG
(CHEMBL238050 | di-(4-acetamido)phenyl 2-((2S,3R)-2...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1P(=O)(Oc1ccc(NC(C)=O)cc1)Oc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C30H35N4O6P/c1-5-19(2)28(31)29(37)34-18-22-8-6-7-9-27(22)30(34)41(38,39-25-14-10-23(11-15-25)32-20(3)35)40-26-16-12-24(13-17-26)33-21(4)36/h6-17,19,28,30H,5,18,31H2,1-4H3,(H,32,35)(H,33,36)/t19-,28+,30?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 9.10E+3n/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


J Med Chem 50: 5568-70 (2007)


Article DOI: 10.1021/jm701005a
BindingDB Entry DOI: 10.7270/Q2S75G2R
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8


(Homo sapiens (Human))
BDBM50225422
PNG
(CHEMBL237860 | diphenyl 2-((2S,3R)-2-amino-3-methy...)
Show SMILES CC[C@@H](C)[C@H](N)C(=O)N1Cc2ccccc2C1P(=O)(Oc1ccccc1)Oc1ccccc1
Show InChI InChI=1S/C26H29N2O4P/c1-3-19(2)24(27)25(29)28-18-20-12-10-11-17-23(20)26(28)33(30,31-21-13-6-4-7-14-21)32-22-15-8-5-9-16-22/h4-17,19,24,26H,3,18,27H2,1-2H3/t19-,24+,26?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.90E+4n/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


J Med Chem 50: 5568-70 (2007)


Article DOI: 10.1021/jm701005a
BindingDB Entry DOI: 10.7270/Q2S75G2R
More data for this
Ligand-Target Pair